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09_Fact_Path_Vir_2_2012_Dent - IS MU
09_Fact_Path_Vir_2_2012_Dent - IS MU

... T cells and activated macrophages (cell-mediated immunity) B cells and producers of antibodies (humoral immunity) ...
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Jess - PBL-J-2015

... A pathogen is then shed from body (exit). Pathogens can be spread between hosts, e.g. passing through the gastrointestinal tract, droplet spread from the respiratory system, direct spread from the urogenital system. ...
Suppressing the immune system
Suppressing the immune system

... The cells then enter the spleen, which filters the blood and helps remove old and dying blood cells. During this process immune cells learn to recognise the myelin antigen as harmless because in the spleen, the particles are engulfed by macrophages (white blood cells that engulf pathogens and unwant ...
PowerPoint 簡報
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... The general process of lymphocyte extravasation is similar to neutrophil extravasation. Naïve T-cells circulate indiscriminately to secondary lymphoid tissue throughout the body. ...
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... – Identify aberrant clonal expansions (Blood cancers) – Track clonal expansions (Immune response) ...
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... b. Their tissue origins c. The type of chemical they use to kill cells D. Stains that are used to identify them e. The researchers who described them ...
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Presentation 3 Innate Immunity

... • Understand the concept of innate immunity • Describe the characteristics of the response • Understand recognition processes • Describe the cells involved and their effector functions ...
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DEFENSE - Immune 15-16

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Review for Quarter 1 10-29-2013

... together to keep them from escaping phagocytosis. That way, a phagocyte can phagocytose more than one pathogen at a time. Interferons are produced by one of your cells that’s been invaded by viruses. Interferons tell uninfected nearby cells to get ready for the invasion. ...
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lec1

Non-specific host defenses
Non-specific host defenses

... Complement fixation • Antibodies interaction with complement proteins (Eg. Classical pathway) thereby delivering the compliment to ...
Innate and Adaptive Immunity - Molecular and Cell Biology
Innate and Adaptive Immunity - Molecular and Cell Biology

... signal transduction pathway. Binding of either type to the receptors causes Tyr PO4ylation of the different receptorassociated kinases, and of the different Stat proteins associated with these. Ifn-/ complex has a unique pathway activating p113; both activate p91/p84. These pathways then converge ...
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Lec

... "Complement" is a collective term to describe a system of about 20 different proteins, many of which are enzyme precursors. All these are present normally among the plasma proteins and also among the plasma proteins that leak out of the capillaries into the tissue spaces. The enzyme precursors are n ...
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Immunology 03 MED

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The Immune System - Clark Pleasant Community School Corp
The Immune System - Clark Pleasant Community School Corp

... • Variable part fits only one antigen • Very specific ...
Chapter 21 - Fundamentals of Microbiology
Chapter 21 - Fundamentals of Microbiology

Four Types of Adaptive Immunity
Four Types of Adaptive Immunity

... 1. IgD antibody receptor on B cell binds its specific antigen/epitope 2. B cell is activated and undergoes clonal selection: the B cell proliferates and differentiates into two types of cell populations: Memory B cells and Plasma Cells 3. Plasma cells secrete antibodies specific for the original epi ...
InfectiousDisease
InfectiousDisease

Immune System Guided Notes
Immune System Guided Notes

... ______________________ and ______________________ – released by T cells, increase immune response and directly destroy pathogens ...
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microbio 14

... losses of CTCTT sequences to form stop codons and oscillate gene expression ...
antibody antigen interaction
antibody antigen interaction

... Antigen-antibody reaction, is a specific chemical interaction between antibodies produced by B cells of the white blood cells and antigens during immune reaction. It is the fundamental reaction in the body by which the body is protected from complex foreign molecules. Biological Aspects of Antibody- ...
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bacterial Pathogenesis

... ► how long it takes the inoculum to result in clinical damage e. acquisition of Fe from transferrin, lactoferrin, or other Febinding proteins (e.g. siderophores as virulence factors) ...
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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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