Lecture 7 Host Defense Against Infection
... Located in serosa, under epithelial surfaces and adjacent to blood vessels, nerves and glands Capable of phagocytosis Process and present antigen using MHC class I or II receptors LPS can directly induce release of mast cell mediators Complement (C3a and C5a) induce mast cells to release mediators ...
... Located in serosa, under epithelial surfaces and adjacent to blood vessels, nerves and glands Capable of phagocytosis Process and present antigen using MHC class I or II receptors LPS can directly induce release of mast cell mediators Complement (C3a and C5a) induce mast cells to release mediators ...
Dental Microbiology #211 IMMUNOLOGY Lecture 1
... A substance capable of inducing an adaptive immune response is called an Antigen. In order to induce an immune response an antigen (Ag) must be foreign to the host. Microorganisms express a large variety of proteins carbohydrates and lipids that are foreign to the host. Red blood cells, proteins fro ...
... A substance capable of inducing an adaptive immune response is called an Antigen. In order to induce an immune response an antigen (Ag) must be foreign to the host. Microorganisms express a large variety of proteins carbohydrates and lipids that are foreign to the host. Red blood cells, proteins fro ...
Notes on Allergy
... Results in prolonged TH1 bias on subsequent exposure to foreign substances, including potential allergens ...
... Results in prolonged TH1 bias on subsequent exposure to foreign substances, including potential allergens ...
Viruses and host defenses
... Infect and measure responses over time Use mutant animals/genetic defects in humans Infect and block specific defenses Do in vitro studies ...
... Infect and measure responses over time Use mutant animals/genetic defects in humans Infect and block specific defenses Do in vitro studies ...
9.2 Types of Antibodies and Vaccines ppt
... Many parents are afraid to let their kids play in the dirt and get sick when they are young. While it is important that we protect our children, not letting them interact with dirt or ever get sick can have really bad consequences. Discuss why children need to interact with dirt and get sick sometim ...
... Many parents are afraid to let their kids play in the dirt and get sick when they are young. While it is important that we protect our children, not letting them interact with dirt or ever get sick can have really bad consequences. Discuss why children need to interact with dirt and get sick sometim ...
Immune-system-preview-nobelprize-org
... Click on 02 on the right hand side. After completing your task, click on Read More on the lower left hand side. Answer the following questions. 1. What is a vaccine? ...
... Click on 02 on the right hand side. After completing your task, click on Read More on the lower left hand side. Answer the following questions. 1. What is a vaccine? ...
Document
... • Contact one – eczematous reaction at the point of contact with allergen, usually hapten, occurs within 72 hours of antigen challenge • Tuberculin one – an area of red firm swelling of the ...
... • Contact one – eczematous reaction at the point of contact with allergen, usually hapten, occurs within 72 hours of antigen challenge • Tuberculin one – an area of red firm swelling of the ...
your body`s defense against infection lesson 2
... antibodies Proteins that attach to antigens, keeping them from harming the body ...
... antibodies Proteins that attach to antigens, keeping them from harming the body ...
How is a vaccine prepared?
... 4. Transplant Problems • Transplanted organs have foreign antigens on their cells because they come from another person. • Immune system recognizes antigens as foreign and attacks, causing rejection. • Transplant patients take drugs to reduce the effectiveness of their immune system, but as a resul ...
... 4. Transplant Problems • Transplanted organs have foreign antigens on their cells because they come from another person. • Immune system recognizes antigens as foreign and attacks, causing rejection. • Transplant patients take drugs to reduce the effectiveness of their immune system, but as a resul ...
Type II hypersensitivity
... This type involves the death of cells bearing Ab attached to antigen , Abs are of IgG & possibly IgM classes react directly with antigen on the surface of tissue cells (SELF). Complement participate in this reaction & promote cytolysis or cytotoxic reaction. E.g. hemolytic reaction drug, allergies, ...
... This type involves the death of cells bearing Ab attached to antigen , Abs are of IgG & possibly IgM classes react directly with antigen on the surface of tissue cells (SELF). Complement participate in this reaction & promote cytolysis or cytotoxic reaction. E.g. hemolytic reaction drug, allergies, ...
Mechanisms of Disordered Immune Regulation
... Autoimmunity, Hematologic or lymphoproliferative disorders (lymphadenopathy, splenomegaly, nodular hyperplasia) High incidence of malignancy - lymphoreticular and gastrointestinal Prognosis is not good as XLA ...
... Autoimmunity, Hematologic or lymphoproliferative disorders (lymphadenopathy, splenomegaly, nodular hyperplasia) High incidence of malignancy - lymphoreticular and gastrointestinal Prognosis is not good as XLA ...
the immune response
... Systemic lupus erythematosus (SLE) Arises from autoantibodies formed against fragments of single or double stranded DNA and some chromosomal proteins (e.g. histones). Because these molecules are widespread throughout the body, the inflammation is broadly distributed Nephritis Nephritis, Skin lesions ...
... Systemic lupus erythematosus (SLE) Arises from autoantibodies formed against fragments of single or double stranded DNA and some chromosomal proteins (e.g. histones). Because these molecules are widespread throughout the body, the inflammation is broadly distributed Nephritis Nephritis, Skin lesions ...
SLE (systemic lupus erythematosus)
... epitope. Any of these antibodies can bind thenucleosome particle to form an immune complex. Such potentially autoreactive B cells probably exist normally in the circulation but, provided that T-celltolerance is intact, they are never activated because this requires T cells to bereactive against the ...
... epitope. Any of these antibodies can bind thenucleosome particle to form an immune complex. Such potentially autoreactive B cells probably exist normally in the circulation but, provided that T-celltolerance is intact, they are never activated because this requires T cells to bereactive against the ...
Disease as a Failure of Homeostasis
... Inject the pathogen (VACCINE) into the organism The body responds by making ANTIBODIES and having the WBC’s ATTACK the invader Some WBC’s SPECIFIC for this pathogen remain in the body for a long time to continue PROTECTION from future attacks. ...
... Inject the pathogen (VACCINE) into the organism The body responds by making ANTIBODIES and having the WBC’s ATTACK the invader Some WBC’s SPECIFIC for this pathogen remain in the body for a long time to continue PROTECTION from future attacks. ...
128. immune_team_
... complement : • we check C2 and C3 levels, if both are decreased, it means they have been used a lot , so it’s the ...
... complement : • we check C2 and C3 levels, if both are decreased, it means they have been used a lot , so it’s the ...
L3 Defence Against Disease
... 2. Producing Antibodies – these tag and disable pathogens 3. Producing Antitoxins – these counteract the toxins produced by pathogens ...
... 2. Producing Antibodies – these tag and disable pathogens 3. Producing Antitoxins – these counteract the toxins produced by pathogens ...
Glossary of Terms
... T-cells generally see pieces of the antigen while B-cells can either bind to the whole antigen or to a piece of the antigen. Epitope:The small area on the antigen that the B-cell or T-cell actually recognizes and binds. Cytokine: Small molecules secreted during an immune response that help to signal ...
... T-cells generally see pieces of the antigen while B-cells can either bind to the whole antigen or to a piece of the antigen. Epitope:The small area on the antigen that the B-cell or T-cell actually recognizes and binds. Cytokine: Small molecules secreted during an immune response that help to signal ...
Non specific response to disease - Science Website
... Step 1 - When the pathogen enters, our body realises it is foreign because it has markers on its outer membrane. These markers are Antigens. (Our own cells have these but our body recognises that they are our own and not a threat) Step 2 - Antibodies in our blood attach to the foreign antigens and t ...
... Step 1 - When the pathogen enters, our body realises it is foreign because it has markers on its outer membrane. These markers are Antigens. (Our own cells have these but our body recognises that they are our own and not a threat) Step 2 - Antibodies in our blood attach to the foreign antigens and t ...
Humoral Immune Response
... Helper T cells – turn on immune response Suppressor T cells – turn off immune response Cytotoxic T cells directly attack antigen ...
... Helper T cells – turn on immune response Suppressor T cells – turn off immune response Cytotoxic T cells directly attack antigen ...
File - Biology with Radjewski
... When low blood-pressure causes (un-stretched) sensory neurons to provide feedback information that blood pressure has decreased, reflexes are activated to restore optimal blood pressure. The action required to return blood pressure to “normal” in this example include the activation of thirst, stimul ...
... When low blood-pressure causes (un-stretched) sensory neurons to provide feedback information that blood pressure has decreased, reflexes are activated to restore optimal blood pressure. The action required to return blood pressure to “normal” in this example include the activation of thirst, stimul ...
Complement system
The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.