IMMUNODEFICIENCY
... • Respiratory burst is normal. • Associated with NK cell defect, platelet and neurological disorders ...
... • Respiratory burst is normal. • Associated with NK cell defect, platelet and neurological disorders ...
Antibodies - INAYA Medical College
... – React optimally at a temperature of 37C, and are so called warm agglutinins. – These antibodies can cross the placental barrier, e.g. IgG ...
... – React optimally at a temperature of 37C, and are so called warm agglutinins. – These antibodies can cross the placental barrier, e.g. IgG ...
RH Factor
... – If type A, will have anti-B antibodies that will attack – If type B, will have anti-A antibodies that will attack ...
... – If type A, will have anti-B antibodies that will attack – If type B, will have anti-A antibodies that will attack ...
1. dia
... By IgM type antibodies. Differences in transport makes all the differece: Antibodies spec. to blood group antigens ...
... By IgM type antibodies. Differences in transport makes all the differece: Antibodies spec. to blood group antigens ...
Dental Microbiology #211 IMMUNOLOGY Lecture 1
... The notion of specificity can be explained in both chemical and geometric terms. Each antibody (Ab) molecule is specific for, and can interact only with one antigen (Ag) specificity. Eg: Ab produced in response to influenza virus type A will protect the host against the influenza A, but not against ...
... The notion of specificity can be explained in both chemical and geometric terms. Each antibody (Ab) molecule is specific for, and can interact only with one antigen (Ag) specificity. Eg: Ab produced in response to influenza virus type A will protect the host against the influenza A, but not against ...
The Immune System
... • An infectious disease is caused when a pathogen is passed from one organism to another, disrupting homeostasis in the organism’s body. – Agents called pathogens are the cause of infections. Some but not all types are bacteria, viruses, protozoans, fungi and parasites. ...
... • An infectious disease is caused when a pathogen is passed from one organism to another, disrupting homeostasis in the organism’s body. – Agents called pathogens are the cause of infections. Some but not all types are bacteria, viruses, protozoans, fungi and parasites. ...
Ch. 43 - Harford Community College
... cytokines and specific binding to class I MHC-antigen complexes on a target (infected, transplanted, or cancerous) cell. • The T cell then secretes perforins, which form pores in the target cell membrane, causing the cell to lyse. ...
... cytokines and specific binding to class I MHC-antigen complexes on a target (infected, transplanted, or cancerous) cell. • The T cell then secretes perforins, which form pores in the target cell membrane, causing the cell to lyse. ...
and t-lymphocyte immune deficiencies
... Genetic deficiencies of the classical complement pathway (C1, C2 and C4) are associated with a high prevalence of autoimmune disease, particularly severe systemic lupus erythematosus (SLE) Mannose-binding lectin deficiency is very common (5% of the population). Individuals with complete mannos ...
... Genetic deficiencies of the classical complement pathway (C1, C2 and C4) are associated with a high prevalence of autoimmune disease, particularly severe systemic lupus erythematosus (SLE) Mannose-binding lectin deficiency is very common (5% of the population). Individuals with complete mannos ...
introduction and overview
... responses Diversification: converting one response into multiple types Turning responses off so that they don’t get out of control Memory The ability to respond to a changing environment by inventing new Ag receptors ...
... responses Diversification: converting one response into multiple types Turning responses off so that they don’t get out of control Memory The ability to respond to a changing environment by inventing new Ag receptors ...
Chapter 19
... • Autograft: Use of one's own tissue • Isograft: Use of identical twin's tissue • Allograft: Use of tissue from another person • Xenotransplantation product: Use of non-human tissue • Graft-versus-host disease can result from transplanted bone marrow that contains immunocompetent cells ...
... • Autograft: Use of one's own tissue • Isograft: Use of identical twin's tissue • Allograft: Use of tissue from another person • Xenotransplantation product: Use of non-human tissue • Graft-versus-host disease can result from transplanted bone marrow that contains immunocompetent cells ...
Adverse Immune Reactions and Immune Deficiencies
... Autoimmune diseases Chronic inflammatory conditions that arise as a result of either Ab- or T cell-mediated responses to self-antigens ...
... Autoimmune diseases Chronic inflammatory conditions that arise as a result of either Ab- or T cell-mediated responses to self-antigens ...
Immunty to inf 2 MT
... Secrete factors that kill parasites without ingestion Secrete cytokines that activate other immune cells Synthesize nitric oxide that act as parasite toxin Activation of macrophages is a general feature of early stage of infection ...
... Secrete factors that kill parasites without ingestion Secrete cytokines that activate other immune cells Synthesize nitric oxide that act as parasite toxin Activation of macrophages is a general feature of early stage of infection ...
Immune System - Dr. Annette M. Parrott
... Immunoglobulin classes • IgD is attached to B-cell plasma membrane • IgM is released during primary response. Indicates current infection. • IgG is the most aboundant. Can cross placenta & blood vessel walls. • IgA found in body secretions prevents attachment to body surfaces. • IgE causes release ...
... Immunoglobulin classes • IgD is attached to B-cell plasma membrane • IgM is released during primary response. Indicates current infection. • IgG is the most aboundant. Can cross placenta & blood vessel walls. • IgA found in body secretions prevents attachment to body surfaces. • IgE causes release ...
Wk5- Intracell Sig
... – induces secretion of IL-10 to inhibit activated dendritic cells (adaptive immune response) and macrophages (innate immune response), as well as inhibiting production of inflammatory cytokines IL-12 and TNF-α. ...
... – induces secretion of IL-10 to inhibit activated dendritic cells (adaptive immune response) and macrophages (innate immune response), as well as inhibiting production of inflammatory cytokines IL-12 and TNF-α. ...
Chapter 24: The Immune System
... “work against foreign body” 1o Ab function: bind Ag to B lymphocyte and initiate production of additional antibodies (usually IgM) Other Ab functions: bind to pathogens and target them for destruction (via several different mechanisms!) ...
... “work against foreign body” 1o Ab function: bind Ag to B lymphocyte and initiate production of additional antibodies (usually IgM) Other Ab functions: bind to pathogens and target them for destruction (via several different mechanisms!) ...
Chapter 13- The Body`s Defense System
... 6.Some B-cells become Memory B-cells that wait for the next infection by the same pathogen. 7.Some B-cells become Plasma B-cells which fight pathogens by creating antibodies. Antibodies bind to antigens of pathogens and clump them together or activate compliment proteins to initiate the inflammatory ...
... 6.Some B-cells become Memory B-cells that wait for the next infection by the same pathogen. 7.Some B-cells become Plasma B-cells which fight pathogens by creating antibodies. Antibodies bind to antigens of pathogens and clump them together or activate compliment proteins to initiate the inflammatory ...
Complement system
The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.