Presentation
... – Post-streptococcal glomerulonephritis: immune complexes of Strep antigen + anti-Strep antibodies; formed in circulation or GBM – Not known why immune complex diseases develop in rare individuals after common infections ...
... – Post-streptococcal glomerulonephritis: immune complexes of Strep antigen + anti-Strep antibodies; formed in circulation or GBM – Not known why immune complex diseases develop in rare individuals after common infections ...
Acquired Haemolytic Anaemias
... Neoantigen type Formerly known as immune complex / innocent bystander Old theory suggested drug formed immune complex with anti-drug antibody attached non-specifically to red cell destruction by complement However where complex displays rare specificity for a particular antigen on RBC e.g. ...
... Neoantigen type Formerly known as immune complex / innocent bystander Old theory suggested drug formed immune complex with anti-drug antibody attached non-specifically to red cell destruction by complement However where complex displays rare specificity for a particular antigen on RBC e.g. ...
03-390 Final – Fall 2013 Name:_____________________________ each
... i) Describe how do the anti-VSG antibodies kill the parasite? 3pts By binding to the Variant Surface Glycoprotein the Abs -> opsonize the parasite -> facilitate phagocytosis by phagocytes -> activate the classical pathway of the complement system -> lysis by MAC and opsonization by C3b No hypersensi ...
... i) Describe how do the anti-VSG antibodies kill the parasite? 3pts By binding to the Variant Surface Glycoprotein the Abs -> opsonize the parasite -> facilitate phagocytosis by phagocytes -> activate the classical pathway of the complement system -> lysis by MAC and opsonization by C3b No hypersensi ...
I. BACTERIA Percent Shift from Gram Positive (facultative) to Gram
... tissues). PMNs release oxygen radicals to kill microbes in the phagolysozome) but these radicals when released (leaked) outside the PMNs can cause damage to surrounding host tissues. • Complement can damage host tissue (bystander membrane attack complex). • Our periodontal host cells (fibroblasts, e ...
... tissues). PMNs release oxygen radicals to kill microbes in the phagolysozome) but these radicals when released (leaked) outside the PMNs can cause damage to surrounding host tissues. • Complement can damage host tissue (bystander membrane attack complex). • Our periodontal host cells (fibroblasts, e ...
hypersensitivity - immunology.unideb.hu
... This is the so-called "speckled" pattern of staining which is more characteristic of the presence of autoantibodies to extractable nuclear antigens, particularly ribonucleoprotein. This pattern is not very specific, but may be seen with an entity called "mixed connective tissue disease" which is a m ...
... This is the so-called "speckled" pattern of staining which is more characteristic of the presence of autoantibodies to extractable nuclear antigens, particularly ribonucleoprotein. This pattern is not very specific, but may be seen with an entity called "mixed connective tissue disease" which is a m ...
anatomy of the immune system
... • are found in tissues like the skin, near blood vessels. • are activated after antigen binds to a specific type of antibody called IgE that is attached to receptors on the mast cell. • activated mast cells release substances that contribute to inflammation, such as histamine. ...
... • are found in tissues like the skin, near blood vessels. • are activated after antigen binds to a specific type of antibody called IgE that is attached to receptors on the mast cell. • activated mast cells release substances that contribute to inflammation, such as histamine. ...
10. practice 2011
... Immunofluorescence staining pattern with antibody to IgG staining immune complexes at the dermal-epidermal junction. If such a pattern is seen only in skin involved by a rash, then the diagnosis is probably DLE, but if this pattern appears even in skin uninvolved by a rash, then the diagnosis is SLE ...
... Immunofluorescence staining pattern with antibody to IgG staining immune complexes at the dermal-epidermal junction. If such a pattern is seen only in skin involved by a rash, then the diagnosis is probably DLE, but if this pattern appears even in skin uninvolved by a rash, then the diagnosis is SLE ...
1. dia
... Decreased bactericid ability based on oxygen is a diverse genetic deficiency where the synthesis of reactive oxygen radicals for killing intracellular pathogens is decreased in immunecompetent cells. (most frequently the sureoxide synthesis is disturbed). The deficiency leads to formation of granulo ...
... Decreased bactericid ability based on oxygen is a diverse genetic deficiency where the synthesis of reactive oxygen radicals for killing intracellular pathogens is decreased in immunecompetent cells. (most frequently the sureoxide synthesis is disturbed). The deficiency leads to formation of granulo ...
DISEASE NOTES
... than injury) that interferes with _____________________ _______________________, causing ________________, ____________________, or _______________ problems ...
... than injury) that interferes with _____________________ _______________________, causing ________________, ____________________, or _______________ problems ...
Document
... • Autoimmune diseases are failures of the immune system. – White blood cells cannot recognize healthy cells. – White blood cells attack healthy body cells. – Tissues fail because of attack. ...
... • Autoimmune diseases are failures of the immune system. – White blood cells cannot recognize healthy cells. – White blood cells attack healthy body cells. – Tissues fail because of attack. ...
31.5 Overreactions of the Immune System KEY CONCEPT unhealthy.
... In autoimmune diseases, white blood cells attack the body’s healthy cells. • Autoimmune diseases are failures of the immune system. – White blood cells cannot recognize healthy cells. – White blood cells attack healthy body cells. – Tissues fail because of attack. ...
... In autoimmune diseases, white blood cells attack the body’s healthy cells. • Autoimmune diseases are failures of the immune system. – White blood cells cannot recognize healthy cells. – White blood cells attack healthy body cells. – Tissues fail because of attack. ...
Adverse Immune Reactions and Immune Deficiencies
... X-linked Severe combined immune deficiencies (SCID). Patients suffer from total susceptibility to infections since neither T nor B cells are generated. Inherited defects of phagocytic function. Inherited defects of complement: Loss of specific complement components. Inability to form the MAC and/or ...
... X-linked Severe combined immune deficiencies (SCID). Patients suffer from total susceptibility to infections since neither T nor B cells are generated. Inherited defects of phagocytic function. Inherited defects of complement: Loss of specific complement components. Inability to form the MAC and/or ...
4th Lecture
... The liver macrophages, or Kupffer cells, are primarily responsible for particulate and microbial clearance from the blood. They express high levels of MHC class II, are actively phagocytic, and release several soluble mediators. Thus, they are the primary cells responsible for the acute phase resp ...
... The liver macrophages, or Kupffer cells, are primarily responsible for particulate and microbial clearance from the blood. They express high levels of MHC class II, are actively phagocytic, and release several soluble mediators. Thus, they are the primary cells responsible for the acute phase resp ...
10th practice 2012
... Immunofluorescence staining pattern with antibody to IgG staining immune complexes at the dermal-epidermal junction. If such a pattern is seen only in skin involved by a rash, then the diagnosis is probably DLE, but if this pattern appears even in skin uninvolved by a rash, then the diagnosis is SLE ...
... Immunofluorescence staining pattern with antibody to IgG staining immune complexes at the dermal-epidermal junction. If such a pattern is seen only in skin involved by a rash, then the diagnosis is probably DLE, but if this pattern appears even in skin uninvolved by a rash, then the diagnosis is SLE ...
Immune System
... coordinatio\n and alert system for pathogens. As a result, the immune system does not funtion and the body becomes easily infected with pathogens that a healthy immune system could have fought off. When an individual has 1/6 th the normal amount of helper T-cells, they are considered to have AIDS (a ...
... coordinatio\n and alert system for pathogens. As a result, the immune system does not funtion and the body becomes easily infected with pathogens that a healthy immune system could have fought off. When an individual has 1/6 th the normal amount of helper T-cells, they are considered to have AIDS (a ...
1999 examination
... Latex bead agglutination may occur with IgM antibodies and soluble antigens if the antigens are first attached to latex beads. ...
... Latex bead agglutination may occur with IgM antibodies and soluble antigens if the antigens are first attached to latex beads. ...
Human Body Systems
... Body creates an immune response after being exposed to a pathogen or a vaccine Memory cells are produced so this immunity lasts (sometimes even a lifetime) ...
... Body creates an immune response after being exposed to a pathogen or a vaccine Memory cells are produced so this immunity lasts (sometimes even a lifetime) ...
The Immune System - University of Arizona
... Antibody Structure – C Region • The C region is made up of a series of Ig• ...
... Antibody Structure – C Region • The C region is made up of a series of Ig• ...
Complement system
The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.