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Antigenicity - immunology.unideb.hu
Antigenicity - immunology.unideb.hu

... • May form crosslinks between antigens (precipitation / agglutination – see later) • Neutralization: binding can block the enzyme or toxin or other virulence factors of pathogens and can avoid damage to host cells ...
13 The Lymphatic System and Immunity
13 The Lymphatic System and Immunity

B-Cells - misslongscience
B-Cells - misslongscience

... • To recall the second and third lines of defence Oh! What’s occurring? ...
Reminder: Answer all questions, and strive to be both brief and
Reminder: Answer all questions, and strive to be both brief and

... 47. Immune conjugates of antibody and radionuclides are used to treat cancer, but are limited by the a. need to use radioactive elements that are not poisonous to the patient b. desire to use elements that decay to non-radioactive products c. difficulty to chemically couple the radioactive atom to a ...
Secretor Status
Secretor Status

... The term ‘secretor’ or ‘non-secretor’ refers to the ability of an individual to secrete ABO blood group antigens in bodily fluids such as saliva, sweat, tears, serum and the gastrointestinal mucus secretions. The function of ABO antigens remain an enigma, however it has recently been suggested that ...
Document
Document

... Describe the different functions performed by the two subpopulations of NK cells in the blood and how they are distinguished. B. How does this compare with NK-cell subpopulations in other tissues? 3–38 The function of uterine NK cells (uNK) is to _____. a. kill virus-infected cells b. secrete growth ...
Toxins produced by gram positive bacteria(2)
Toxins produced by gram positive bacteria(2)

... Enterotoxins are superantigens that are even more heatstable than S. aureus; therefore, organisms are not always recovered from incriminated food. They polymerize into tubes that pierce membranes, resulting in the loss of important molecules and, eventually, in osmotic lysis . They stimulate the vom ...
Lecture 2: Innate Immunity
Lecture 2: Innate Immunity

Objectives 24 - U
Objectives 24 - U

... - final result is fragmentation of DNA, disintegration of nucleus and blebbing of membranes into apoptotic bodies which are internalized by macrophages - apoptosis does not elicit immune reaction; mediated through exhibition of phophatidyl serine (PtdSer) on cell surface  this phospholipid is in th ...
MICR 130 Chapter 16
MICR 130 Chapter 16

Chapter Objectives: Chapter 43 the Immune System
Chapter Objectives: Chapter 43 the Immune System

Nonspecific vs. Specific Defense Mechanisms
Nonspecific vs. Specific Defense Mechanisms

... » Most common type » Direct skin contact with... – Poison oak/ivy, heavy metals (e.g. Pb, Hg, Ba, etc.), misc. chemicals in cosmetics, deodorants, foods, etc. – 1-3 days to respond Symptoms are caused by lymphokines released by Killer T Cells » Treat with corticosteroid drugs (e.g. cortisone) » Why ...
Immune System Lecture_Spring 2002
Immune System Lecture_Spring 2002

... Cardinal signs: Redness, heat, swelling, pain ...
Complement and its role in innate and adaptive immune
Complement and its role in innate and adaptive immune

... system. Discovered in 1896 by Bordet as a heat-labile component of serum, it was so named for its ability to ‘complement’ the antibacterial properties of antibody in the heat-stabile fraction of serum. It is now appreciated that complement is a complex network of plasma and membrane-associated serum ...
Immune System Powerpoint
Immune System Powerpoint

... Both responses produce memory cells. – specialized T and B cells – provide acquired (active) immunity ...
Lymphatic and Immune System Information Sheet
Lymphatic and Immune System Information Sheet

... larger vessels that eventually drain into one of two lymphatic ducts, right lymphatic duct or thoracic duct. These vessels have valves that keep the lymph from flowing backwards and it is always flowing toward the thoracic cavity. The right lymphatic duct receives purified lymph from the right side ...
Immune System
Immune System

... - These classes perform different roles and help direct the appropriate immune response for each antigen they encounter 2. Specific antigen-binding site = how antibodies recognize specific antigens (the top of the “Y”) - variable region = antigen specific - 100,000’s of different varieties in this r ...
Immunology for Life Scientists. 2nd Edition Brochure
Immunology for Life Scientists. 2nd Edition Brochure

Unit 4 Mind Maps
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... Describe the role of cytokines Damage to connective tissue causes, __________ cells to release a chemical ...
Nanodiamond as Hemoglobin based Artificial Blood
Nanodiamond as Hemoglobin based Artificial Blood

Microsoft Word Version
Microsoft Word Version

... Auto-antibodies Auto-antibodies occur in people with certain diseases. These diseases are called autoimmune diseases. In these conditions you make antibodies to normal proteins or structures in a part of your body. The immune system 'mistakes' a protein in your body and treats it as a foreign antige ...
Name: Date: Period: _____ The Immune Response: Web Analysis
Name: Date: Period: _____ The Immune Response: Web Analysis

... 1. The immune system is a network of cells, tissues, and organs that work together to defend the body against pathogens. 2. Once the body senses a pathogen, the immune system signals to the cells to produce chemicals that either regulate their own growth and behavior, call to other immune cells, or ...
Introduction_to_the_Human_Immune_System
Introduction_to_the_Human_Immune_System

... •Initial response to microbes (surveillance and detection of non-self) •Recognizes structures characteristic of microbial pathogens •Not on mammalian cells •Necessary for survival of microbe •Receptors are encoded in germline DNA •will also recognize stressed or injured tisssue ...
Laboratory Applications of Poultry Lecture and Lab Overview
Laboratory Applications of Poultry Lecture and Lab Overview

... B. Glick and his group discovered bursa function, 1956 Produce antibodies ...
AQA Immunity Booklet Answers
AQA Immunity Booklet Answers

... When an antigen is recognised by a type of white blood cell known as a lymphocyte, the resulting process is known as immunity, the ability of our body to protect itself from a disease that we have already experienced. There are two interlinked types of immunity; Cell mediated immunity and humoural i ...
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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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