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Set 6 Immune System and Vaccines
Set 6 Immune System and Vaccines

... Immunodeficiency: for some reason the adaptive immune system does not work Autoimmune diseases: the immune system cannot distinguish self and non-self This is for disambiguation and clarification-AIDS (Module 4) is an example of an ...
Lecture (5) Dr
Lecture (5) Dr

... recognition molecules and has the capacity for long-term memory. ...
International Health
International Health

... the production of antibodies (soluble proteins that bind to foreign antigens) and cell-mediated responses in which specific cells recognize foreign pathogens and destroy them. In the case of viruses or tumors, this response is also vital to the recognition and destruction of virally-infected or tumo ...
and Factor H on fungal surface. Complement evasion Immune
and Factor H on fungal surface. Complement evasion Immune

... production is critical in inducing a protective immune response in primary infection with the pathogen. IFN-γ is pivotal for the host's innate resistance to systemic infection with H. capsulatum. ...
1. Type I allergy
1. Type I allergy

The Babraham Institute
The Babraham Institute

020909.M1-Immuno - Open.Michigan
020909.M1-Immuno - Open.Michigan

... 3. Innate and adaptive immunity. ...
Overview
Overview

... Your body’s ability to resist the pathogens that cause a particular disease is called immunity. You were born with some immunities that were passed on to you from your mother. These immunities lasted for a few months, after which you began to produce antibodies on your own. ...
Immunology Male et al., 8 th Ed. 2013.
Immunology Male et al., 8 th Ed. 2013.

... This course concentrates on the basic and clinical science of the immune system and its relationship to other sciences and biological systems of mammals. This course will concentrate on function-structure relationship of the immune system and its components such as the lymphoid tissue and cells, the ...
Name - Medical Mastermind Community
Name - Medical Mastermind Community

The Adaptive Immune Response B
The Adaptive Immune Response B

Ch 14 Lymphatic System
Ch 14 Lymphatic System

... and non-self thus making antibodies to it’s own cells Ex: type I diabetes mellitus, rheumatoid arthritis, systematic lupus erythematosus Why would the body do such a thing? - A virus while replicating “borrowed” proteins from the host cell and put it into it’s surface so when the immune while attack ...
Document
Document

Coagulation and innate immune responses: can we
Coagulation and innate immune responses: can we

... opsonic properties, and associated with increased expression of leukocyte adhesion molecules (LAMs). In parallel, DAMP-induced complement activation via 1 or more pathways (CP, classical; AP, alternative; LP, lectin) leads to generation of potent active complement factors, C3a and C5a, and the membr ...
Connective tissue mast cells
Connective tissue mast cells

Lymphatic System
Lymphatic System

... Generally same composition as plasma (except doesn’t contain plasma proteins) Some excess fluid stays in tissue and is not recollected by capillaries ...
immune response lecture3
immune response lecture3

... infection with Plasmodia. Duffy antigen Absence of Duffy antigen: Duffy antigen present on RBCs acts as a receptor for Plasmodium vivax. Its absence limits infection with this parasite. Haemoglobin S: its presence in RBCs provides immunity against Plasmodium falciparum because the parasite cannot fe ...
17 Specific Immune Response
17 Specific Immune Response

... – Express CD4 proteins in their plasma membranes – Amplify the response of B-cells and other helper T-cells – Activated by binding to antigen • Once activated, the Helper T-cell secretes IL-2 • IL-2 is a cytokine that that acts on B-cells and other T-cells ...
Lecture outline : Immunity This is a protective or defense mechanism
Lecture outline : Immunity This is a protective or defense mechanism

Ch. 24 Presentation
Ch. 24 Presentation

... pathogens, agents that cause disease.  The immune system is the body’s system of defenses against agents that cause disease.  Innate immunity is a series of defenses that – act immediately upon infection and – are the same whether or not the pathogen has been encountered before. ...
1. Diagnosis of patients with immunodeficiency
1. Diagnosis of patients with immunodeficiency

... Inherited defects of the complement system are very rare. If you refer to your second MB course in immunology you will recall that the central component of complement is C3, which is present in serum at a concentration of about 1g/L. C3 lies at the pivotal point in both the classical and alternative ...
Immunology in Rheumatic Diseases
Immunology in Rheumatic Diseases

... Respond to antigens by becoming plasma cell - make antibodies against the specific antigen ...
antigen recognition by b-cell and t
antigen recognition by b-cell and t

... IgG antibodies consist of four polypeptide chains. ...
Immunity
Immunity

... Table 23-3, p.385 ...
Immunity
Immunity

...  Primary lymphocytes respond to antigen by clonal selection, clonal expansion, and differentiation into effector cells and secondary (memory) lymphocytes  Secondary lymphocytes are able to respond more rapidly and effectively to subsequent exposures to the antigen ...
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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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