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The Immune System
The Immune System

... • Our tissues contain their own antigens (proteins capable of generating antibodies). • Our immune system recognizes these antigens as belonging to ourselves, and does not produce antibodies against them. • When a tissue or organ is transplanted, the recipient’s immune system will not recognize it a ...
1 We discussed function of white blood cells ,different type of white
1 We discussed function of white blood cells ,different type of white

Hypersensitivity
Hypersensitivity

... of IgG which binds to antigen (allergen) before it reaches IgE coated cells. – Monocolonal anti-IgE – inject, binds to receptors on mast cells blocking them from the IgE. ...
Early cytokine release in response to live largely complement independent
Early cytokine release in response to live largely complement independent

and the T cells - immunology.unideb.hu
and the T cells - immunology.unideb.hu

... Tc ...
Chapter 18
Chapter 18

... Antigens and Antibodies • Antigens – unique molecules on cell surface • used to distinguish self from foreign • foreign antigens generate immune response ...
E. The Immune Response
E. The Immune Response

Immune system notes
Immune system notes

... system as a “foreign” invader. WBC’s have protein markers called antibodies on their cell’ membrane ...
Name___________________________ Immune System Anatomy
Name___________________________ Immune System Anatomy

... the immune system not only attacks the pathogens. It also attacks body cells with the similar molecules. ...
Altered Immune Responses - rivier.instructure.com.
Altered Immune Responses - rivier.instructure.com.

... Cell- mediated Immunity • Cytokines – Immune response involves complex interactions of T-cells, B-cells, monocytes, and neutrophils - depends on Cytokines – Acts as messenger between the cell types – Instruct cells to alter their proliferation, differentiation, secretion, or activity – 60 different ...
Blood
Blood

... • Depending on the pathogen, infection will cause changes in the proportion of WBC’s in the blood ...
Intravenous Immunoglobulin in Autoimmune Neuromuscular
Intravenous Immunoglobulin in Autoimmune Neuromuscular

... Intravenous immunoglobulin (IVIG) modulates multiple immunologicevents (blue boxes) involved in the pathogenesis of autoimmune neuromusculardiseases. Diseases for which specific therapeutic actions of IVIG are supportedby experimental evidence are listed in each box. In autoimmune neuromusculardisea ...
Resistance of The Body to Infection Immunity and Allergy
Resistance of The Body to Infection Immunity and Allergy

... immunity or B-cell immunity (because B lymphocytes produce the antibodies). The second type is achieved through the formation of large numbers of activated T lymphocytes that are specifically crafted in the lymph nodes to destroy the foreign agent. This type of immunity is called cell-mediated immun ...
Immune Response to Infectious Diseases Objective Questions 1
Immune Response to Infectious Diseases Objective Questions 1

... 1. What are the major groups of pathogens? Provide examples of diseases caused by each of the groups. 2. In general, why are infectious diseases such a huge problem world wide? 3. What is the basic structure of a virus? 4. Explain the viral replication process, in generic terms. 5. Describe the host ...
Nature of the Immune System
Nature of the Immune System

Immune System – Part 2
Immune System – Part 2

... Antigen-binding site VARIES between each unique antibody The CONSTANT region defines Ab class and effector action ...
Detailed Outline and Resources for Lesson Planning
Detailed Outline and Resources for Lesson Planning

... o Secondary lymphoid organs are sites of immune responses and include (Fig 12-1):  Lymph nodes  Filtering stations for foreign particles (macrophages eat)  Pathogens recognized by lymphocytes set off response and node swells  Spleen  Left upper quadrant above stomach  Similar function to nodes ...
7.5 Immune response – questions and answers Q1. Bk Ch7 S7.6 Q1
7.5 Immune response – questions and answers Q1. Bk Ch7 S7.6 Q1

... Active immunity involves the body producing antibodies in response to the presence of a foreign antigen. Passive immunity occurs when antibodies specific to a particular pathogen are injected into a person rather than the person producing the antibodies. Active immunity is long lasting because the b ...
13_Immune_system_-_Specifics_of_children`s_immunity_
13_Immune_system_-_Specifics_of_children`s_immunity_

... they are eliminated by exocytosis; • Some peptides however, undergo a very important separate process at this stage; • Instead of being eliminated, they attach to a host molecule and end up being expressed on the surface of the cell within a groove on the molecule (antigen presentation). ...
An Agent-Based Model Demonstrates that the
An Agent-Based Model Demonstrates that the

Complement: a key system for immune surveillance and homeostasis
Complement: a key system for immune surveillance and homeostasis

Epitope mapping
Epitope mapping

... Examples of substances recognized as foreign (non-self) Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones o ...
3 pharmacy B cells
3 pharmacy B cells

... IMMUNCOMPLEX complexe of (1)antigens-(2)antibodies (3)complement components complex ...
Immune Activity Questions:
Immune Activity Questions:

... Immune Activity Questions: Questions: Attach your individual’s questions to the team’s project. 1. Discuss some of the ways microbes evade the body's immune system. 2. Distinguish between antigen and antibody. Then explain how antibodies and macrophages work together during an antigen-antibody react ...
Microbiology – Chapter 15
Microbiology – Chapter 15

... 6. Small molecules that are too small to cause an immune response are called haptens. Penicillin is an example. By itself, too small to be antigenic, but it combines with serum proteins and then can become antigenic (penicillin allergy ) ...
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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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