exuberance in the development of cortical
... The comparison of juvenile and adult connections is complicated by variations with age in the uptake, transport and diffusion of axonally transported substances that are used to trace them. Some tracers (for example, lipophilic molecules such as carbocyanine dyes) label young, unmyelinated axons wel ...
... The comparison of juvenile and adult connections is complicated by variations with age in the uptake, transport and diffusion of axonally transported substances that are used to trace them. Some tracers (for example, lipophilic molecules such as carbocyanine dyes) label young, unmyelinated axons wel ...
Carlisi_preprint_revisions2
... 2008), underpinned by abnormalities in fronto-striatal, fronto-temporo-parietal and frontocerebellar networks (Hart et al., 2012, Hart et al., 2013, Rubia et al., 2014a). Furthermore, they have deficits in timing functions (Noreika et al., 2013) and in “hot” EF, referring to EF involving motivation ...
... 2008), underpinned by abnormalities in fronto-striatal, fronto-temporo-parietal and frontocerebellar networks (Hart et al., 2012, Hart et al., 2013, Rubia et al., 2014a). Furthermore, they have deficits in timing functions (Noreika et al., 2013) and in “hot” EF, referring to EF involving motivation ...
Magnocellular and Parvocellular Contributions to
... particular response property in the cortex cannot be taken as conclusive evidence for input from 1 channel. Physiological approaches based on response latency (Maunsell and Schiller, 1984; Berson, 1985; Petersen et al., 1988) are similarly limited in that they can only provide conclusive evidence fo ...
... particular response property in the cortex cannot be taken as conclusive evidence for input from 1 channel. Physiological approaches based on response latency (Maunsell and Schiller, 1984; Berson, 1985; Petersen et al., 1988) are similarly limited in that they can only provide conclusive evidence fo ...
Effects of the Metabotropic Glutamate Receptor Antagonist MCPG
... In any case, the data are clear that MC PG treatment does not reliably block NMDA receptor-dependent LTD and LTP in CA1. These results seemed to exclude the hypothesis that activation of MC PG-sensitive mGluRs is a requirement for induction of these forms of synaptic plasticity. Because of the simil ...
... In any case, the data are clear that MC PG treatment does not reliably block NMDA receptor-dependent LTD and LTP in CA1. These results seemed to exclude the hypothesis that activation of MC PG-sensitive mGluRs is a requirement for induction of these forms of synaptic plasticity. Because of the simil ...
Galvanic Skin Response in Mood Disorders
... patients were included. Some studies did not use emotional stimuli, however were included as GSR measures were conducted separately from stimuli presentation. A greater proportion of studies reported results in support of a specific GSR profile for mood disorders as well as indicating GSR variation ...
... patients were included. Some studies did not use emotional stimuli, however were included as GSR measures were conducted separately from stimuli presentation. A greater proportion of studies reported results in support of a specific GSR profile for mood disorders as well as indicating GSR variation ...
Somatosensory processes subserving perception and action
... parietal cortex (APC) (Jones & Powell 1970; Jones et al. 1979; Whitsel et al. 1978). This area was originally referred to as the first somatosensory cortex (SI), but more recently it has been suggested that only Brodmann area (BA) 3b can be considered to be the homologue of the primary area SI in no ...
... parietal cortex (APC) (Jones & Powell 1970; Jones et al. 1979; Whitsel et al. 1978). This area was originally referred to as the first somatosensory cortex (SI), but more recently it has been suggested that only Brodmann area (BA) 3b can be considered to be the homologue of the primary area SI in no ...
The impact of continuity editing in narrative film on event segmentation
... neural mechanisms can be distinguished: stimulus-driven increases of processing and attention-driven regulation. Measures of brain activity obtained using fMRI are a valuable source of data for studying the operation of both mechanisms. By stimulus-driven increases, we mean additional neural activit ...
... neural mechanisms can be distinguished: stimulus-driven increases of processing and attention-driven regulation. Measures of brain activity obtained using fMRI are a valuable source of data for studying the operation of both mechanisms. By stimulus-driven increases, we mean additional neural activit ...
Response characteristics of neurons in the pulvinar of awake cats to
... In higher mammals visual information from the retina can reach the visual cortex either directly, via the dorsal lateral geniculate nucleus (LGNd), or by a more indirect pathway, via the superior colliculus and pretectal nuclear complex to the lateral posterior-pulvinar complex (LP-P) which in turn ...
... In higher mammals visual information from the retina can reach the visual cortex either directly, via the dorsal lateral geniculate nucleus (LGNd), or by a more indirect pathway, via the superior colliculus and pretectal nuclear complex to the lateral posterior-pulvinar complex (LP-P) which in turn ...
PDF
... has recently divided this level into two distinct levels—superficial feedforward sweeps, which are limited to visual areas, and deep feedforward sweeps, which reach the prefrontal cortex (Lamme, 2010). This distinction leads him to claim that consciousness and attention are orthogonal. This issue is ...
... has recently divided this level into two distinct levels—superficial feedforward sweeps, which are limited to visual areas, and deep feedforward sweeps, which reach the prefrontal cortex (Lamme, 2010). This distinction leads him to claim that consciousness and attention are orthogonal. This issue is ...
Levels of kinesin light chain and dynein intermediate
... New York) is specific for tau phosphorylated at Ser396/404 [37]. The following antibodies were also used: mouse monoclonal antibodies to Dynein intermediate chain (DIC) (MAB1618, Chemicon), to tubulin-!3 (T8660, Sigma), to "-tubulin (T9026, Sigma, DM1A) to GSK-3! (TPKI, Transduction Laboratories), t ...
... New York) is specific for tau phosphorylated at Ser396/404 [37]. The following antibodies were also used: mouse monoclonal antibodies to Dynein intermediate chain (DIC) (MAB1618, Chemicon), to tubulin-!3 (T8660, Sigma), to "-tubulin (T9026, Sigma, DM1A) to GSK-3! (TPKI, Transduction Laboratories), t ...
Are cortical spikes conveyed to contralateral
... method referenced to cortical spike discharges. The waveform of CCAP was characterized by a slow-rising negative potential change that preceded the cortical spike discharge and continued to increase after it occurred (Fig. 2). As shown in Fig. 4, the following common features among all 20 patients w ...
... method referenced to cortical spike discharges. The waveform of CCAP was characterized by a slow-rising negative potential change that preceded the cortical spike discharge and continued to increase after it occurred (Fig. 2). As shown in Fig. 4, the following common features among all 20 patients w ...
Alpha-beta and Gamma Rhythms Subserve Feedback and
... Visually induced responses Forty-three human subjects were instructed to attentively monitor a visual stimulus for unpredictable changes, in order to engage both bottom-up and top-down influences. This paradigm reliably induces gamma-band activity in visual cortex (Hoogenboom et al., 2006). While su ...
... Visually induced responses Forty-three human subjects were instructed to attentively monitor a visual stimulus for unpredictable changes, in order to engage both bottom-up and top-down influences. This paradigm reliably induces gamma-band activity in visual cortex (Hoogenboom et al., 2006). While su ...
Coordinated Optimization of Visual Cortical Maps
... layout observed for OP maps in the visual cortex [2–4]. Large scale empirical studies of the arrangement of pinwheel positions and spatial densities in the visual cortex of four species widely separated in mammalian evolution recently showed that orientation maps although spatially irregular precise ...
... layout observed for OP maps in the visual cortex [2–4]. Large scale empirical studies of the arrangement of pinwheel positions and spatial densities in the visual cortex of four species widely separated in mammalian evolution recently showed that orientation maps although spatially irregular precise ...
CRB1 Gene Mutations Are Associated with
... ation determines how commonly these two disorders occur together. Studies of LCA cases not infrequently report a concordance with keratoconus.1,24 Studies of keratoconus populations on the other hand, rarely find LCA cases.25 It is presumed that the visual disability resulting from LCA is generally ...
... ation determines how commonly these two disorders occur together. Studies of LCA cases not infrequently report a concordance with keratoconus.1,24 Studies of keratoconus populations on the other hand, rarely find LCA cases.25 It is presumed that the visual disability resulting from LCA is generally ...
Neuroanatomical correlates of the near response: voluntary
... inhibition of accommodation to blur induced optically by a ±5.0-D glass lens (Opt-blur; Fig. 2B and D): the subjects see alternately a sharp or a blurred image; (iii) VPA requiring large amplitude (~ ± 5 D), high-frequency (0.3 Hz), voluntary positive accommodation in the viewing eye in response to ...
... inhibition of accommodation to blur induced optically by a ±5.0-D glass lens (Opt-blur; Fig. 2B and D): the subjects see alternately a sharp or a blurred image; (iii) VPA requiring large amplitude (~ ± 5 D), high-frequency (0.3 Hz), voluntary positive accommodation in the viewing eye in response to ...
Ictal SPECT in patients with rapid eye movement
... Introduction Rapid eye movement (REM) sleep behaviour disorder is a parasomnia characterized by acting out dreams with screaming, hitting, thrashing and frequent self-injury. It has gained major attention because 81% of the patients with the idiopathic REM sleep behaviour disorder form convert withi ...
... Introduction Rapid eye movement (REM) sleep behaviour disorder is a parasomnia characterized by acting out dreams with screaming, hitting, thrashing and frequent self-injury. It has gained major attention because 81% of the patients with the idiopathic REM sleep behaviour disorder form convert withi ...
Changes in emotion after circumscribed surgical
... in humans, and to determine whether these regions can be dissociated in terms of their contribution to different aspects of emotional processing. In pursuing this aim we were able to obtain evidence from patients with surgically circumscribed lesions of different parts of the prefrontal cortex, as d ...
... in humans, and to determine whether these regions can be dissociated in terms of their contribution to different aspects of emotional processing. In pursuing this aim we were able to obtain evidence from patients with surgically circumscribed lesions of different parts of the prefrontal cortex, as d ...
Selectivity for the Shape, Size, and Orientation of Objects for
... the light (visual-motor neurons) or no activation in the dark (visualdominant neurons). Of these visually responsive neurons, more than half (n ⫽ 66) responded during the object-fixation task (object-type). Among these, 55 were tested for their shape selectivity during the object-fixation task, and ...
... the light (visual-motor neurons) or no activation in the dark (visualdominant neurons). Of these visually responsive neurons, more than half (n ⫽ 66) responded during the object-fixation task (object-type). Among these, 55 were tested for their shape selectivity during the object-fixation task, and ...
Retinotopic Organization and Functional Subdivisions of the Human
... crystal display projector (Epson, Long Beach, CA) outside the scanner room onto a translucent screen located at the end of the scanner bore. Subjects viewed the screen at a total path length of 60 cm through a mirror attached to the head coil. The screen subtended 30° of visual angle in the horizont ...
... crystal display projector (Epson, Long Beach, CA) outside the scanner room onto a translucent screen located at the end of the scanner bore. Subjects viewed the screen at a total path length of 60 cm through a mirror attached to the head coil. The screen subtended 30° of visual angle in the horizont ...
Selectivity for the Shape, Size, and Orientation of Objects for
... the light (visual-motor neurons) or no activation in the dark (visualdominant neurons). Of these visually responsive neurons, more than half (n ⫽ 66) responded during the object-fixation task (object-type). Among these, 55 were tested for their shape selectivity during the object-fixation task, and ...
... the light (visual-motor neurons) or no activation in the dark (visualdominant neurons). Of these visually responsive neurons, more than half (n ⫽ 66) responded during the object-fixation task (object-type). Among these, 55 were tested for their shape selectivity during the object-fixation task, and ...
Fut u re N
... falsifiable predictions made by the malignant synaptic growth hypothesis and describe the avenues of treatment that hold the greatest promise under this hypothesis. ...
... falsifiable predictions made by the malignant synaptic growth hypothesis and describe the avenues of treatment that hold the greatest promise under this hypothesis. ...
Precise visuotopic organization of the blind spot representation in
... specific penetration angles). We monitored the transition from the opercular surface to the roof of the calcarine sulcus by advancing the microelectrode in 200-m steps. We stopped advancing the microelectrode when the first transition from a central RF (typically ⬃5° eccentricity) to a peripheral R ...
... specific penetration angles). We monitored the transition from the opercular surface to the roof of the calcarine sulcus by advancing the microelectrode in 200-m steps. We stopped advancing the microelectrode when the first transition from a central RF (typically ⬃5° eccentricity) to a peripheral R ...
Patterns of sensory intermodality relationships in the cerebral cortex
... areas was determined according to Nissl stain cytoarchitecture (Welker, '71, '76; Welker and Sinha, '721, and by the lateral callosal band of labeling through which the border passed (Figs. 2B,C; Olavarria et al., '84). The medial border of area S1 was also delineated by bands of dense callosal labe ...
... areas was determined according to Nissl stain cytoarchitecture (Welker, '71, '76; Welker and Sinha, '721, and by the lateral callosal band of labeling through which the border passed (Figs. 2B,C; Olavarria et al., '84). The medial border of area S1 was also delineated by bands of dense callosal labe ...
AN INTEGRATIVE THEORY OF LOCUS
... accord well with the characteristic anatomy of these systems (widely distributed projections throughout the forebrain), and it is easy to understand how disturbances in such basic and pervasive functions would have profound disruptive effects on cognition, emotion, and behavior such as those associa ...
... accord well with the characteristic anatomy of these systems (widely distributed projections throughout the forebrain), and it is easy to understand how disturbances in such basic and pervasive functions would have profound disruptive effects on cognition, emotion, and behavior such as those associa ...
Adaptive Gain and Optimal Performance
... accord well with the characteristic anatomy of these systems (widely distributed projections throughout the forebrain), and it is easy to understand how disturbances in such basic and pervasive functions would have profound disruptive effects on cognition, emotion, and behavior such as those associa ...
... accord well with the characteristic anatomy of these systems (widely distributed projections throughout the forebrain), and it is easy to understand how disturbances in such basic and pervasive functions would have profound disruptive effects on cognition, emotion, and behavior such as those associa ...