Slides
... §Saccharomyces cerevisiae and the Crabtree effect §S. cerevisiae is the only yeast that can produce ethanol and CO2 in such large quantities §S. cerevisiae ferments carbohydrates efficiently and dominates its environment due to the Crabtree effect §Unlike most fermenting organisms S. cerevisiae can ...
... §Saccharomyces cerevisiae and the Crabtree effect §S. cerevisiae is the only yeast that can produce ethanol and CO2 in such large quantities §S. cerevisiae ferments carbohydrates efficiently and dominates its environment due to the Crabtree effect §Unlike most fermenting organisms S. cerevisiae can ...
PROTEIN PHOSPHORYLATION AND CELLULAR REGULATION, I by
... of phosphorylase constitutes a physiologically significant regulatory mechanism. Resting muscle was reported to contain phosphorylase predominantly in the a form, whereas electrically stimulated muscle contained th e b form (4). As will be discussed later (see below) the reverse is actually true. Re ...
... of phosphorylase constitutes a physiologically significant regulatory mechanism. Resting muscle was reported to contain phosphorylase predominantly in the a form, whereas electrically stimulated muscle contained th e b form (4). As will be discussed later (see below) the reverse is actually true. Re ...
PDF - Oxford Academic
... Studies on the mammalian cell division cycle have revealed that pRb proteins act as ‘pocket domain’ proteins regulating G1 to S phase transition through phosphorylation-dependent interaction with the E2F family transcription factors, repressing or activating genes required for cell cycle progression ...
... Studies on the mammalian cell division cycle have revealed that pRb proteins act as ‘pocket domain’ proteins regulating G1 to S phase transition through phosphorylation-dependent interaction with the E2F family transcription factors, repressing or activating genes required for cell cycle progression ...
Sequence-based prediction of protein interaction
... To effectively utilize the large number of extracted features and to deal with the imbalanced data classification problems, we herein describe an integrative random forest method for predicting interaction sites. Random forest tree has been applied to protein–protein interaction prediction in our re ...
... To effectively utilize the large number of extracted features and to deal with the imbalanced data classification problems, we herein describe an integrative random forest method for predicting interaction sites. Random forest tree has been applied to protein–protein interaction prediction in our re ...
Supplementary information
... and non-specific manner, while ECFP-EYFP protein is only subject to molecular sieving effect, resulting from relatively cluttered nuclear environment. High mobility was also expected in the case of p53 L344P (Sup. 1A), reflecting its mostly monomeric quaternary structure as compared to the other tes ...
... and non-specific manner, while ECFP-EYFP protein is only subject to molecular sieving effect, resulting from relatively cluttered nuclear environment. High mobility was also expected in the case of p53 L344P (Sup. 1A), reflecting its mostly monomeric quaternary structure as compared to the other tes ...
Evidence for the presence of a glucosensor in hypothalamus
... of nutrients including glucose. In mammals, sensors to detect levels of glucose are found in pancreatic -cells (31) where phosphorylation of glucose by hexokinase-IV (HK-IV or glucokinase, GK) plays a central role (27). HK-IV or GK has appropriate kinetics (low affinity for glucose), lacks end-produ ...
... of nutrients including glucose. In mammals, sensors to detect levels of glucose are found in pancreatic -cells (31) where phosphorylation of glucose by hexokinase-IV (HK-IV or glucokinase, GK) plays a central role (27). HK-IV or GK has appropriate kinetics (low affinity for glucose), lacks end-produ ...
1 ENZYME KINETICS [APPLICATION OF UV
... influenced by several factors such as substrate concentration, temperature, pH and the presence of inhibitors. The substrate concentration factor can be explained in terms of collision theory: the more substrate molecules available, the quicker the enzyme molecules collide and bind with them. The te ...
... influenced by several factors such as substrate concentration, temperature, pH and the presence of inhibitors. The substrate concentration factor can be explained in terms of collision theory: the more substrate molecules available, the quicker the enzyme molecules collide and bind with them. The te ...
Glycolysis coloring sheet
... study tools. Polyethylene terephthalate (sometimes written poly(ethylene terephthalate)), commonly abbreviated PET, PETE, or the obsolete PETP or PET-P, is the most. Artisteer - web design generator for Joomla templates, Wordpress themes, Drupal themes, Blogger templates and DNN skins. This course c ...
... study tools. Polyethylene terephthalate (sometimes written poly(ethylene terephthalate)), commonly abbreviated PET, PETE, or the obsolete PETP or PET-P, is the most. Artisteer - web design generator for Joomla templates, Wordpress themes, Drupal themes, Blogger templates and DNN skins. This course c ...
Effects of signaling on subcellular localization of MITF
... Microphthalmia-associated transcription factor (MITF) is the master regulator of melanocytes and plays a crucial role in melanoma. MITF is known from the literature to be regulated by signaling, for example through the MAPK pathway which mediates signals with protein phosphorylations. The MAPK pathw ...
... Microphthalmia-associated transcription factor (MITF) is the master regulator of melanocytes and plays a crucial role in melanoma. MITF is known from the literature to be regulated by signaling, for example through the MAPK pathway which mediates signals with protein phosphorylations. The MAPK pathw ...
Bio1A - Lec 9 slides File
... REQUIRED portions of the enzyme. • often required for proper protein folding • typically required at the active site -For bonding -Supplies electrons or functional groups for the reaction -Temporarily for E-S transient complexes ...
... REQUIRED portions of the enzyme. • often required for proper protein folding • typically required at the active site -For bonding -Supplies electrons or functional groups for the reaction -Temporarily for E-S transient complexes ...
Lecture 2 - cholesterol _CVS block
... Cholesterol synthesis • Synthesized in all tissues • Major sites for synthesis- liver, adrenal cortex, testes, ovaries and intestine • All carbon atoms are derived from acetyl CoA • Enzymes involved in biosynthesis are partly located in ER and partly in cytoplasm ...
... Cholesterol synthesis • Synthesized in all tissues • Major sites for synthesis- liver, adrenal cortex, testes, ovaries and intestine • All carbon atoms are derived from acetyl CoA • Enzymes involved in biosynthesis are partly located in ER and partly in cytoplasm ...
digestion of carbohydrates - KSU Faculty Member websites
... [1] The NAD-linked conversion of pyruvate to lactate ( anaerobic ) . [2] Oxidation via the respiratory chain ( generating 2 x 3 ATP ) . The oxidation of the aldehyde group of glyceraldehyde 3-phosphate to a carboxyl group is coupled to the attachment of pi to the carboxyl group . The high-energy pho ...
... [1] The NAD-linked conversion of pyruvate to lactate ( anaerobic ) . [2] Oxidation via the respiratory chain ( generating 2 x 3 ATP ) . The oxidation of the aldehyde group of glyceraldehyde 3-phosphate to a carboxyl group is coupled to the attachment of pi to the carboxyl group . The high-energy pho ...
1 ENZYME KINETICS [APPLICATION OF UV
... influenced by several factors such as substrate concentration, temperature, pH and the presence of inhibitors. The substrate concentration factor can be explained in terms of collision theory: the more substrate molecules available, the quicker the enzyme molecules collide and bind with them. The te ...
... influenced by several factors such as substrate concentration, temperature, pH and the presence of inhibitors. The substrate concentration factor can be explained in terms of collision theory: the more substrate molecules available, the quicker the enzyme molecules collide and bind with them. The te ...
CAJANUS CAJAN INDUCED LIVER DAMAGE Research Article
... animals by biuret method11. Standard kit was obtained from Span diagnostics. Statistical analysis The significance of difference among the groups was assed using one way analysis of variance (ANOVA) followed by Bonferroni’s multiple comparison test between the data of control and trea ...
... animals by biuret method11. Standard kit was obtained from Span diagnostics. Statistical analysis The significance of difference among the groups was assed using one way analysis of variance (ANOVA) followed by Bonferroni’s multiple comparison test between the data of control and trea ...
75. In yeast, if the electron transport system is shut down because of
... d) It doesn't matter; both process will produce the same results. __ 88. Which of the following molecules can enter the citric acid cycle? a) proteins b) amino acids c) fatty acids d) pyruvate e) all of the choices are correct __ 89. Which of the following molecules is NOT oxidized during the citric ...
... d) It doesn't matter; both process will produce the same results. __ 88. Which of the following molecules can enter the citric acid cycle? a) proteins b) amino acids c) fatty acids d) pyruvate e) all of the choices are correct __ 89. Which of the following molecules is NOT oxidized during the citric ...
Dynamic targeting of the replication machinery to sites of DNA damage
... clearly demonstrate that DNA-PK plays a direct role in promoting RPAp34 turnover at repair foci, presumably by altering its binding affinity for substrates such as singlestranded DNA or other repair factors. These results provide a dynamic framework for RPA modification in the regulation of repair a ...
... clearly demonstrate that DNA-PK plays a direct role in promoting RPAp34 turnover at repair foci, presumably by altering its binding affinity for substrates such as singlestranded DNA or other repair factors. These results provide a dynamic framework for RPA modification in the regulation of repair a ...
Activation Mechanism of Protein Kinase B by DNA
... higher organisms (Weterings and van Gent, 2004). As a result, two highly efficient DSB repair pathways have evolved in eukaryotic cells: homologous recombination (HR) and nonhomologous end joining (NHEJ) (Weterings and Chen, 2007). The core protein of the DNA-PK multi-protein complex is represented ...
... higher organisms (Weterings and van Gent, 2004). As a result, two highly efficient DSB repair pathways have evolved in eukaryotic cells: homologous recombination (HR) and nonhomologous end joining (NHEJ) (Weterings and Chen, 2007). The core protein of the DNA-PK multi-protein complex is represented ...
Lecture t
... in methane – covalent electrons are shared equally between the C and the Hs of methane and the two Os of O2 - they are equally electronegative BUT - O is a very electronegative element – one of the most potent oxidizing agents when CO2 is formed - electrons are shared less equally between C and O – ...
... in methane – covalent electrons are shared equally between the C and the Hs of methane and the two Os of O2 - they are equally electronegative BUT - O is a very electronegative element – one of the most potent oxidizing agents when CO2 is formed - electrons are shared less equally between C and O – ...
Heavy Metal Stress. Activation of Distinct Mitogen
... Cadmium- and copper-responsive genes have been shown to code for signal transduction components, such as the Arabidopsis mitogen-activated protein kinase kinase kinase (MAPKKK) MEKK1, transcription factors, stress-induced proteins, proteins participating in protein folding, and sulfur and glutathion ...
... Cadmium- and copper-responsive genes have been shown to code for signal transduction components, such as the Arabidopsis mitogen-activated protein kinase kinase kinase (MAPKKK) MEKK1, transcription factors, stress-induced proteins, proteins participating in protein folding, and sulfur and glutathion ...
Journal of Biotechnology Evaluation of 13C isotopic tracers for
... (MID) of each metabolite for a given set of fluxes. The sensitivity of the MIDs, in turn, to changes in the pathway fluxes ultimately determines the confidence of flux estimates, which are as important as the flux values themselves (Antoniewicz et al., 2006). Stationary MFA is conducted when the labeled ...
... (MID) of each metabolite for a given set of fluxes. The sensitivity of the MIDs, in turn, to changes in the pathway fluxes ultimately determines the confidence of flux estimates, which are as important as the flux values themselves (Antoniewicz et al., 2006). Stationary MFA is conducted when the labeled ...
The Concentration of Phosphatidylethanolamine in
... of type 2 diabetes is increasing, and therefore understanding the underlying physiology is of major importance. Up to 75% of patients with obesity and diabetes also suffer from nonalcoholic fatty liver disease (NAFLD) (1,2), indicating that the liver plays an important role in the etiology of obesit ...
... of type 2 diabetes is increasing, and therefore understanding the underlying physiology is of major importance. Up to 75% of patients with obesity and diabetes also suffer from nonalcoholic fatty liver disease (NAFLD) (1,2), indicating that the liver plays an important role in the etiology of obesit ...
Glycerol is a major substrate for glucose, glycogen, and
... 1971). Similarly, tissue glycogen begins to accumulate by embryonic day (e) 6 (via the uronic acid pathway), peaking on e12, declining 50% by e13, and then increasing >4-fold by e20 (Hazelwood, 1971). Even though several substrates can serve as precursors for glucose and glycogen synthesis (Langslow ...
... 1971). Similarly, tissue glycogen begins to accumulate by embryonic day (e) 6 (via the uronic acid pathway), peaking on e12, declining 50% by e13, and then increasing >4-fold by e20 (Hazelwood, 1971). Even though several substrates can serve as precursors for glucose and glycogen synthesis (Langslow ...
7 Dynamics of pyruvate metabolism in Lactococcus lactis
... The lactic acid bacterium Lactococcus lactis is commonly used in the dairy industry for the manufacture of fermented milk and cheese. This is mainly due to the ability of this organism to rapidly convert the sugars present in milk to lactic acid, whereby a preservative effect is obtained. L. lactis ...
... The lactic acid bacterium Lactococcus lactis is commonly used in the dairy industry for the manufacture of fermented milk and cheese. This is mainly due to the ability of this organism to rapidly convert the sugars present in milk to lactic acid, whereby a preservative effect is obtained. L. lactis ...
Biochemical Journal
... BRG1-associated factor 60; CDK, cyclin-dependent kinase; C/EBP, CCAAT/enhancer-binding protein; c-IAP1/2, cellular inhibitor of apoptosis 1/2; CREB, cAMP-response-element-binding protein; CSBP, cytokine-suppressive anti-inflammatory drug-binding protein; DDB2, damaged-DNA-binding complex 2; D domain ...
... BRG1-associated factor 60; CDK, cyclin-dependent kinase; C/EBP, CCAAT/enhancer-binding protein; c-IAP1/2, cellular inhibitor of apoptosis 1/2; CREB, cAMP-response-element-binding protein; CSBP, cytokine-suppressive anti-inflammatory drug-binding protein; DDB2, damaged-DNA-binding complex 2; D domain ...
Nutrition, Metabolism, and Body Temperature Regulation
... The monosaccharide glucose is the carbohydrate molecule ultimately used as fuel by body cells to produce ATP. Carbohydrate digestion also yields fructose and galactose, but these monosaccharides are converted to glucose by the liver before they enter the general circulation. Many body cells use fats ...
... The monosaccharide glucose is the carbohydrate molecule ultimately used as fuel by body cells to produce ATP. Carbohydrate digestion also yields fructose and galactose, but these monosaccharides are converted to glucose by the liver before they enter the general circulation. Many body cells use fats ...
Phosphorylation
Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).