Carbamoyl phosphate synthetase - Department of Biochemistry
... no effect by itself, although it does bind with good affinity to the enzyme [3]. Indeed, the small effect that IMP does have changes from activation to inhibition if the temperarare is lowered below -35°C [4]. ...
... no effect by itself, although it does bind with good affinity to the enzyme [3]. Indeed, the small effect that IMP does have changes from activation to inhibition if the temperarare is lowered below -35°C [4]. ...
The Wine Expert: Fermentation of Fructose
... the yeast were phenotypically characterized, the genotype was also studied. The genes for Hexokinase I and Hexokinase II were sequenced since it was assumed that these two enzymes have key functions. Within the coding region of Hexokinase I it was determined that a mutation occured at position 513 w ...
... the yeast were phenotypically characterized, the genotype was also studied. The genes for Hexokinase I and Hexokinase II were sequenced since it was assumed that these two enzymes have key functions. Within the coding region of Hexokinase I it was determined that a mutation occured at position 513 w ...
3 - Dr. Jerry Cronin
... maintain high intracellular K+ concentration and high extracellular Na+ concentration • Maintains electrochemical gradients essential for functions of muscle and nerve tissues • Allows all cells to maintain fluid volume ...
... maintain high intracellular K+ concentration and high extracellular Na+ concentration • Maintains electrochemical gradients essential for functions of muscle and nerve tissues • Allows all cells to maintain fluid volume ...
0 - Microbiology
... not use glucose supplied externally (Doudoroff et al., 1949). Similarly, work on a variety of bacteria showed that whole cells oxidized some added intermediates of the tricarboxylic acid cycle only after prolonged lag periods, yet extracts of these cells contained the enzyme required for the oxidati ...
... not use glucose supplied externally (Doudoroff et al., 1949). Similarly, work on a variety of bacteria showed that whole cells oxidized some added intermediates of the tricarboxylic acid cycle only after prolonged lag periods, yet extracts of these cells contained the enzyme required for the oxidati ...
Hormonal Control of Glucose Metabolism
... lactate, free fatty acids (FFA), and ketone bodies (acetoacetate and j3-hydroxybutyrate), the fluctuations of which vary more widely. The reason why plasma glucose concentration must be maintained in a narrow range of concentration is related to the deleterious effects of both hypoglycemia and hyper ...
... lactate, free fatty acids (FFA), and ketone bodies (acetoacetate and j3-hydroxybutyrate), the fluctuations of which vary more widely. The reason why plasma glucose concentration must be maintained in a narrow range of concentration is related to the deleterious effects of both hypoglycemia and hyper ...
The Growth of Micro-organisms in Relation to their
... as the energy source was the factor limiting growth, the dry weight of organism produced was proportional to the weight of energy source added. It is of particular interest that for a given carbohydrate the three organisms produced approximately the same dry wt. yields. DeMoss, Bard & Gunsalus (1951 ...
... as the energy source was the factor limiting growth, the dry weight of organism produced was proportional to the weight of energy source added. It is of particular interest that for a given carbohydrate the three organisms produced approximately the same dry wt. yields. DeMoss, Bard & Gunsalus (1951 ...
Lecture 24
... maintenance of protein structure and functionality is difficult. The expressed proteins have a short shelf life, if not stored correctly, which makes protein storage difficult. One of the other challenges of using a prokaryotic system such as E. coli is that posttranslational modifications may not b ...
... maintenance of protein structure and functionality is difficult. The expressed proteins have a short shelf life, if not stored correctly, which makes protein storage difficult. One of the other challenges of using a prokaryotic system such as E. coli is that posttranslational modifications may not b ...
The origin of the eukaryotic cell: A genomic investigation
... and that it existed in the progenote, a cellular domain that was the ancestor to both the chronocyte and the prokaryotic cells. Therefore, when one finds a protein in eukaryotic cells that is structurally similar but has little or no sequential homology to those found in prokaryotic cells, the best ...
... and that it existed in the progenote, a cellular domain that was the ancestor to both the chronocyte and the prokaryotic cells. Therefore, when one finds a protein in eukaryotic cells that is structurally similar but has little or no sequential homology to those found in prokaryotic cells, the best ...
Protein Prenylation: Genes, Enzymes, Targets, and Functions
... macromoleculesare often mediated through the covalent attachment of specific chemicalmoieties. The posttranslational modificationof specific proteins by phosphorylation,glycosylation, acetylation, fatty acylation, and methylationhas beenstudied extensively, anda variety of critical biological functi ...
... macromoleculesare often mediated through the covalent attachment of specific chemicalmoieties. The posttranslational modificationof specific proteins by phosphorylation,glycosylation, acetylation, fatty acylation, and methylationhas beenstudied extensively, anda variety of critical biological functi ...
Reactions of glycolysis and gluconeogenesis
... Bypass 3: Conversion of Glucose-6-phosphate to Glucose o Glucose-6-phosphate cannot be converted to glucose by reverse action of hexokinase or glucokinase because of the high positive DGo of that reaction; phosphate transfer from ATP makes that reaction virtually irreversible. o Another enzyme speci ...
... Bypass 3: Conversion of Glucose-6-phosphate to Glucose o Glucose-6-phosphate cannot be converted to glucose by reverse action of hexokinase or glucokinase because of the high positive DGo of that reaction; phosphate transfer from ATP makes that reaction virtually irreversible. o Another enzyme speci ...
Cell biology # 2 - Nutley Public Schools
... maintain high intracellular K+ concentration and high extracellular Na+ concentration • Maintains electrochemical gradients essential for functions of muscle and nerve tissues • Allows all cells to maintain fluid volume ...
... maintain high intracellular K+ concentration and high extracellular Na+ concentration • Maintains electrochemical gradients essential for functions of muscle and nerve tissues • Allows all cells to maintain fluid volume ...
the scf ubiquitin ligase: insights into a molecular machine
... (LRR)), the domain is an arc-shaped α–β-repeat structure that is also found in many protein-binding contexts, including the extracellular-binding domain of certain surface receptors11,12. In most cases, FBLs also seem to involve substrate phosphorylation for their interaction, but this does not seem ...
... (LRR)), the domain is an arc-shaped α–β-repeat structure that is also found in many protein-binding contexts, including the extracellular-binding domain of certain surface receptors11,12. In most cases, FBLs also seem to involve substrate phosphorylation for their interaction, but this does not seem ...
interaction of salinity and temperature on net protein synthesis and
... protein synthesis occurs for 30 min at 22C. The decrease in the rate of protein synthesis at 15C after 30 min of incubation in SSPU medium at 15 and 20%0 may either result in, or result from, the inability of cells to grow at these low salinities. Thus, at growth medium salinities of E-30%0, althoug ...
... protein synthesis occurs for 30 min at 22C. The decrease in the rate of protein synthesis at 15C after 30 min of incubation in SSPU medium at 15 and 20%0 may either result in, or result from, the inability of cells to grow at these low salinities. Thus, at growth medium salinities of E-30%0, althoug ...
Carbohydrate as nutrient in the infant and child: range of
... of infusion. Figure 1 shows a linear correlation between the total rate of appearance of glucose in circulation, as measured by isotopic tracer dilution, and the non-protein respiratory quotient (RQ), so that at glucose Ra of 30 mmol=kgmin (5.4 mg=kgmin or 7.8 g=kgd), the nonprotein RQ became equ ...
... of infusion. Figure 1 shows a linear correlation between the total rate of appearance of glucose in circulation, as measured by isotopic tracer dilution, and the non-protein respiratory quotient (RQ), so that at glucose Ra of 30 mmol=kgmin (5.4 mg=kgmin or 7.8 g=kgd), the nonprotein RQ became equ ...
Compartmentation of the Metabolism of Lactose
... Experimentally, the study of compartmentation in living cells presents certain problems arising from the difficulty of distinguishing between several reservoirs of a substance without fractionating the cell and thereby causing its death. Those attempts which have been made to investigate compartment ...
... Experimentally, the study of compartmentation in living cells presents certain problems arising from the difficulty of distinguishing between several reservoirs of a substance without fractionating the cell and thereby causing its death. Those attempts which have been made to investigate compartment ...
A New Subunit of Cytochrome b6f Complex Undergoes Reversible
... transition. Sequence analysis and biochemical characterization of subunit V shows that it has a one transmembrane ␣-helix topology with two large hydrophilic domains extending on the stromal and lumenal side of the thylakoid membranes, with a lumenal location of the N terminus. Subunit V is reversib ...
... transition. Sequence analysis and biochemical characterization of subunit V shows that it has a one transmembrane ␣-helix topology with two large hydrophilic domains extending on the stromal and lumenal side of the thylakoid membranes, with a lumenal location of the N terminus. Subunit V is reversib ...
SUCCINIC ACID PRODUCTION BY RUMEN BACTERIA By M. F.
... Cells were grown in 800 ml of bicarbonate-buffered medium containing 4% TA, 2% YE, and 2% glucose (Hopgood and Walker 1967). The cells were harvested, washed twice in O' 08M sodium bicarbonate buffer equilibrated with CO 2 , and suspended in 35 ml of the same buffer. The fermentations were carried o ...
... Cells were grown in 800 ml of bicarbonate-buffered medium containing 4% TA, 2% YE, and 2% glucose (Hopgood and Walker 1967). The cells were harvested, washed twice in O' 08M sodium bicarbonate buffer equilibrated with CO 2 , and suspended in 35 ml of the same buffer. The fermentations were carried o ...
pMAL FAQs
... determined by whether this folding pathway leads to a different 3-dimensional structure for the protein. Some proteins, like MBP itself, can fold properly either in the cytoplasm or when exported to the periplasm. However, the normal folding pathway for some proteins is incompatible with passage thr ...
... determined by whether this folding pathway leads to a different 3-dimensional structure for the protein. Some proteins, like MBP itself, can fold properly either in the cytoplasm or when exported to the periplasm. However, the normal folding pathway for some proteins is incompatible with passage thr ...
Informatics approaches to understanding TGFb pathway regulation
... protein subcellular localization (see key). Red T-bars represent the activity of proteins that block information transfer, such as I-Smads (Smad7) and members of the Ski/Sno family. The regulation of pathway components by polyubiquitylation (Ub) is also shown. ...
... protein subcellular localization (see key). Red T-bars represent the activity of proteins that block information transfer, such as I-Smads (Smad7) and members of the Ski/Sno family. The regulation of pathway components by polyubiquitylation (Ub) is also shown. ...
MAPK-mediated Phosphorylation of GATA-1 Promotes Expression and Cell Survival* Bcl-X □
... IL-3 Induces Hyperphosphorylation of GATA-1—The genetic pathway of apoptosis is highly conserved throughout evolution from nematodes to humans (25). Within the regulatory pyramid of this pathway, E4BP4 acts as one of the initial responses to extracellular stimulation, suppresses the suicidal reactio ...
... IL-3 Induces Hyperphosphorylation of GATA-1—The genetic pathway of apoptosis is highly conserved throughout evolution from nematodes to humans (25). Within the regulatory pyramid of this pathway, E4BP4 acts as one of the initial responses to extracellular stimulation, suppresses the suicidal reactio ...
Plk4/SAK/ZYG-1 in the regulation of centriole
... and is required for normal duplication [24,25,27,28]. Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, ...
... and is required for normal duplication [24,25,27,28]. Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, ...
Control of Mitotic Events by Nap1 and the Gin4 Kinase
... Since cyclin-dependent kinases are bound to different cyclins at each stage of the cell cycle, it seems likely that ...
... Since cyclin-dependent kinases are bound to different cyclins at each stage of the cell cycle, it seems likely that ...
TOR SIGNALLING IN BUGS, BRAIN AND BRAWN
... known as hamartin) and TSC2 (tuberin), the products of two tumour suppressor genes, have also been shown to bind mTOR29. TSC1 and TSC2 have a negative effect on TOR signalling, whereas all of the other TOR-binding proteins that have been described above seem to have a positive effect (see below)29–3 ...
... known as hamartin) and TSC2 (tuberin), the products of two tumour suppressor genes, have also been shown to bind mTOR29. TSC1 and TSC2 have a negative effect on TOR signalling, whereas all of the other TOR-binding proteins that have been described above seem to have a positive effect (see below)29–3 ...
Document
... • Oxidative phosphorylation accounts for almost 90% of the ATP generated by cellular respiration • A smaller amount of ATP is formed in glycolysis and the citric acid cycle by substrate-level phosphorylation • For EACH molecule of glucose degraded to CO2 and water by respiration, the cell makes up ...
... • Oxidative phosphorylation accounts for almost 90% of the ATP generated by cellular respiration • A smaller amount of ATP is formed in glycolysis and the citric acid cycle by substrate-level phosphorylation • For EACH molecule of glucose degraded to CO2 and water by respiration, the cell makes up ...
Phosphorylation
Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).