Ammonia Do Ammonia Levels Correlate with Hepatic Encephalopathy?
... ornithine aspartate are encouraging, but the drug is not currently available in the United States. Flumazenil may also be helpful, but is currently indicated only for patients with acute HE and suspected benzodiazepine intake. No oral or long-acting preparations are currently available which would m ...
... ornithine aspartate are encouraging, but the drug is not currently available in the United States. Flumazenil may also be helpful, but is currently indicated only for patients with acute HE and suspected benzodiazepine intake. No oral or long-acting preparations are currently available which would m ...
Determination of De Novo Synthesized Amino Acids in Cellular
... C nuclear magnetic resonance spectroscopy was used to determine the absolute amounts of de novo synthesized amino acids in both the perchloric acid extracts and the hydrolyzed protein fractions of F98 glioma cells incubated for 2 h with 5 mmol/l [U-13C]glucose. 13C NMR spectra of the hydrolyzed prot ...
... C nuclear magnetic resonance spectroscopy was used to determine the absolute amounts of de novo synthesized amino acids in both the perchloric acid extracts and the hydrolyzed protein fractions of F98 glioma cells incubated for 2 h with 5 mmol/l [U-13C]glucose. 13C NMR spectra of the hydrolyzed prot ...
Manipulating redox and ATP balancing for improved production of
... ethanol. Higher cell density of AD12 in sorbitol also suggests that its growth is not limited by acetyl-coA requirement for biosynthesis. 3.2. Effect of the overexpression of A. succinogenes PEPCK Our observations suggest that at least 0.5 moles of ATP per mole of glucose is required for the growth ...
... ethanol. Higher cell density of AD12 in sorbitol also suggests that its growth is not limited by acetyl-coA requirement for biosynthesis. 3.2. Effect of the overexpression of A. succinogenes PEPCK Our observations suggest that at least 0.5 moles of ATP per mole of glucose is required for the growth ...
Chapter 1 Chirality in clinical analysis 1.1. Introduction
... The presence of chiral compounds in human fluids (e.g., serum, urine, spinal fluids) as metabolites of human metabolism or drug metabolism gives the vitality for monitoring levels of these molecules in biofluids. The existence of higher or lower levels of these specific molecules is a marker of huma ...
... The presence of chiral compounds in human fluids (e.g., serum, urine, spinal fluids) as metabolites of human metabolism or drug metabolism gives the vitality for monitoring levels of these molecules in biofluids. The existence of higher or lower levels of these specific molecules is a marker of huma ...
Importance of pH Homeostasis in Metabolic Health and Diseases
... also decreased in low pH media, along with a reduction in glucose uptake. These in vitro observations support the hypothesis that lower extracellular pH may cause insulin resistance in skeletal muscle cells. Other studies [48–50] have suggested a close correlation between organic acid production and ...
... also decreased in low pH media, along with a reduction in glucose uptake. These in vitro observations support the hypothesis that lower extracellular pH may cause insulin resistance in skeletal muscle cells. Other studies [48–50] have suggested a close correlation between organic acid production and ...
Comments on metabolic needs for glucose and the role of
... 2.58 compared with 2.26 with palmitate as substrate, an advantage for glucose of about 14% (Rolfe & Brown, 1997). Therefore there is a real advantage to the oxidation of glucose, compared with fatty acids, when O2 supply may be a limitation, a phenomenon which may account for the improved performanc ...
... 2.58 compared with 2.26 with palmitate as substrate, an advantage for glucose of about 14% (Rolfe & Brown, 1997). Therefore there is a real advantage to the oxidation of glucose, compared with fatty acids, when O2 supply may be a limitation, a phenomenon which may account for the improved performanc ...
energy supply components - The Company of Biologists
... important metabolic sequences; its main metabolic fate is reconversion to the phosphagenform. (Again, arginine may be an exception, seeHochachkaef a/. 19836.) P;, however, is another matter. It is a highly reactive metabolite involved in numerous enzyme reactions in intermediary metabolism. Just as ...
... important metabolic sequences; its main metabolic fate is reconversion to the phosphagenform. (Again, arginine may be an exception, seeHochachkaef a/. 19836.) P;, however, is another matter. It is a highly reactive metabolite involved in numerous enzyme reactions in intermediary metabolism. Just as ...
Thermal selection in Sceloporus occidentalis during exercise recovery
... and prevent animals from escaping while exercising. Animals were run at 0.447 meters per second; S. occidentalis can sprint above speeds of 0.894 meters per second, but it was suspected that exercising them at greater speeds would rapidly lead to exhaustion (Sinvervo et al. 1991). To sustain exercis ...
... and prevent animals from escaping while exercising. Animals were run at 0.447 meters per second; S. occidentalis can sprint above speeds of 0.894 meters per second, but it was suspected that exercising them at greater speeds would rapidly lead to exhaustion (Sinvervo et al. 1991). To sustain exercis ...
Organic solutes in Rubrobacter xylanophilus: the first
... conditions examined, trehalose and MG. In Thermus medium, the increase in the salinity from 0 to 2.5% NaCl resulted in an increase in the concentration of trehalose and MG, which remained fairly constant when the concentration of NaCl was raised to 4 and 5% (Fig. 2a). In M medium, trehalose and MG c ...
... conditions examined, trehalose and MG. In Thermus medium, the increase in the salinity from 0 to 2.5% NaCl resulted in an increase in the concentration of trehalose and MG, which remained fairly constant when the concentration of NaCl was raised to 4 and 5% (Fig. 2a). In M medium, trehalose and MG c ...
Document
... tomography has likewise stunned the scientific community with seemingly complete maps of the cellular interior, and at a yet unknown degree of ‘morphological’ resolution [3,4] (Figure 1a). With those experimental images at hand, we are beginning to appreciate the true extent of cellular macromolecul ...
... tomography has likewise stunned the scientific community with seemingly complete maps of the cellular interior, and at a yet unknown degree of ‘morphological’ resolution [3,4] (Figure 1a). With those experimental images at hand, we are beginning to appreciate the true extent of cellular macromolecul ...
Increasing Pyruvate Dehydrogenase Flux as a Treatment
... rat heart. As yet, there have not been any in vivo studies investigating whether DCA improves cardiac metabolism or function as a potential therapy for diabetic cardiomyopathy. Until recently, we have been limited in our ability to measure metabolism in vivo. However, advances in hyperpolarized 13C ...
... rat heart. As yet, there have not been any in vivo studies investigating whether DCA improves cardiac metabolism or function as a potential therapy for diabetic cardiomyopathy. Until recently, we have been limited in our ability to measure metabolism in vivo. However, advances in hyperpolarized 13C ...
... capsules. Targretin has worked so very well for me that my episodes alarming, and they continued to attribute my I wish it would have been considered as a first option. symptoms to dermatitis and inflamed eczema. Who was I Because of my age and Targretin’s drying effect, I consume to question them? ...
THE EFFECT OF HYBRIDIZATION ON METABOLISM AND HYPOXIA TOLERANCE IN SUNFISH
... (LOE) in 0.8 mg O2 /ml suggests that hybrids and bluegills have a lower hypoxia tolerance than pumpkinseeds. Hybrids showed a unique independence between size and LOE time. Analysis of tissue metabolite levels during normoxia, after LOE, and after a short-term hypoxia exposure suggest that differenc ...
... (LOE) in 0.8 mg O2 /ml suggests that hybrids and bluegills have a lower hypoxia tolerance than pumpkinseeds. Hybrids showed a unique independence between size and LOE time. Analysis of tissue metabolite levels during normoxia, after LOE, and after a short-term hypoxia exposure suggest that differenc ...
The Syndrome of Carnitine Deficiency: Morphological and Metabolic
... the illness began in childhood; there were intermittent episodes of hepatic enlargement and coma. An excessive lipid content was present in muscle tissue, especially in type I fibers, of both cases, and in the liver of the second patient. Ultrastructural studies of muscle tissue ...
... the illness began in childhood; there were intermittent episodes of hepatic enlargement and coma. An excessive lipid content was present in muscle tissue, especially in type I fibers, of both cases, and in the liver of the second patient. Ultrastructural studies of muscle tissue ...
Chapter 8
... Gluconeogenesis is the formation of new glucose molecules from precursors in the liver Precursor molecules include lactate, pyruvate, and ...
... Gluconeogenesis is the formation of new glucose molecules from precursors in the liver Precursor molecules include lactate, pyruvate, and ...
- World Journal of Gastroenterology
... the classical concept of liver cellular damage, as their enzymatic activity might actually reflect key aspects of the physiology and pathophysiology of the liver function. In this study, we summarize the background information and recent findings on the biological role of ALT and AST, and review the ...
... the classical concept of liver cellular damage, as their enzymatic activity might actually reflect key aspects of the physiology and pathophysiology of the liver function. In this study, we summarize the background information and recent findings on the biological role of ALT and AST, and review the ...
The reference range for serum creatinine is as follows
... The assay of creatinine has been based on the reaction of creatinine with alkaline picrate. The reaction has been performed on a protein free filtrate. It has long been recognized that the red color formed in this reaction is not absolutely specific for creatinine, thus results obtained are too high ...
... The assay of creatinine has been based on the reaction of creatinine with alkaline picrate. The reaction has been performed on a protein free filtrate. It has long been recognized that the red color formed in this reaction is not absolutely specific for creatinine, thus results obtained are too high ...
Urinary Organic Acids - Peirson Center for Children
... Assessing Patient Biochemical & Nutritional Individuality ...
... Assessing Patient Biochemical & Nutritional Individuality ...
Hypolipidemic Drugs
... CHO can return to plasma from the tissues in HDL particles and the resulting cholesteryl esters are subsequently transferred to VLDL or LDL One species of LDL – lipoprotein - is associated with atherosclerosis (localised in atherosclerotic lesions). LDL can also activate platelets, constituting a fu ...
... CHO can return to plasma from the tissues in HDL particles and the resulting cholesteryl esters are subsequently transferred to VLDL or LDL One species of LDL – lipoprotein - is associated with atherosclerosis (localised in atherosclerotic lesions). LDL can also activate platelets, constituting a fu ...
Novel physiological and metabolic insights into the beneficial
... phases (Fig 2a, right panel). This EPS was subsequently degraded, but it reappeared during the stationary phase, which may relate to hindrance in the carbon and electron flow as discussed in the following sections. The overall carbon and electron recoveries under these conditions were ~90% after 16 ...
... phases (Fig 2a, right panel). This EPS was subsequently degraded, but it reappeared during the stationary phase, which may relate to hindrance in the carbon and electron flow as discussed in the following sections. The overall carbon and electron recoveries under these conditions were ~90% after 16 ...
Assessing in silico the recruitment and functional spectrum of
... diversity. For a high-level classification, metabolism is subdivided into primary (PM) and secondary (SM) metabolism. SM products are often not essential for survival of the organism and it is generally assumed that SM enzymes stem from PM homologs. Results: We wanted to assess evolutionary relation ...
... diversity. For a high-level classification, metabolism is subdivided into primary (PM) and secondary (SM) metabolism. SM products are often not essential for survival of the organism and it is generally assumed that SM enzymes stem from PM homologs. Results: We wanted to assess evolutionary relation ...
A network-based approach to cell metabolism: from structure to flux balances
... and the linkages to other cell constituents such as enzymes, proteins, and genes. This emerging paradigm for the study of cell metabolism is at the core of an emerging interdisciplinary field called Systems Biology [8–11], which uses a holistic approach to understand the relationships between struct ...
... and the linkages to other cell constituents such as enzymes, proteins, and genes. This emerging paradigm for the study of cell metabolism is at the core of an emerging interdisciplinary field called Systems Biology [8–11], which uses a holistic approach to understand the relationships between struct ...
Inhibitors are structural analogs of true substrate
... A 49-year-old driver complains about unbearable constricting pain behind the breastbone irradiating to the neck. The pain arose 2 hours ago. Objectively: the patient’s condition is grave, he is pale, heart tones are decreased. Laboratory studies revealed high activity of creatine kinase and LDH1. Wh ...
... A 49-year-old driver complains about unbearable constricting pain behind the breastbone irradiating to the neck. The pain arose 2 hours ago. Objectively: the patient’s condition is grave, he is pale, heart tones are decreased. Laboratory studies revealed high activity of creatine kinase and LDH1. Wh ...