ETO-Thesis-Final 061214. - JScholarship
... levels in blood plasma and increased protection from HIV infection. However, in patients infected despite PrEP, systemic drug levels could select for drug resistant mutations. Topically applied microbicides have the potential to overcome this disadvantage of oral dosage since the systemic concentrat ...
... levels in blood plasma and increased protection from HIV infection. However, in patients infected despite PrEP, systemic drug levels could select for drug resistant mutations. Topically applied microbicides have the potential to overcome this disadvantage of oral dosage since the systemic concentrat ...
Design and analysis of metabolic pathways supporting
... Electrosynthesis is a promising approach that enables the biological production of commodities, like fuels and fine chemicals, using renewably produced electricity. Several techniques have been proposed to mediate the transfer of electrons from the cathode to living cells. Of these, the electroproduc ...
... Electrosynthesis is a promising approach that enables the biological production of commodities, like fuels and fine chemicals, using renewably produced electricity. Several techniques have been proposed to mediate the transfer of electrons from the cathode to living cells. Of these, the electroproduc ...
medical chemistry and biochemistry
... 3. Identify the major recognized types of secondary structure and explain supersecondary motifs. 4. Describe the kind and relative strength of the forces that stabilize each order of protein structure and indicate the present state of knowledge concerning the stepwise process by which protein are th ...
... 3. Identify the major recognized types of secondary structure and explain supersecondary motifs. 4. Describe the kind and relative strength of the forces that stabilize each order of protein structure and indicate the present state of knowledge concerning the stepwise process by which protein are th ...
ROUTE OF DRUG ADMINISTRATION AND EXTRAHEPATIC DRUG
... The rate of elimination of the metabolite may be faster or slow er than the rate of formation of the metabolite from the drug. Generally, metabolites such as glucuronide, sulfate, or glycine conjugates are more polar or more w ater soluble than the parent drug and w ill be eliminated more rapidly th ...
... The rate of elimination of the metabolite may be faster or slow er than the rate of formation of the metabolite from the drug. Generally, metabolites such as glucuronide, sulfate, or glycine conjugates are more polar or more w ater soluble than the parent drug and w ill be eliminated more rapidly th ...
farmaceutski fakultet
... When the delivered metabolite is acknowledged to be the primary active entity. When the compound is metabolised to one or more toxicologically active metabolites which could make a significant contribution to tissue/organ responses. When measurement of metabolite concentrations in plasma or other bo ...
... When the delivered metabolite is acknowledged to be the primary active entity. When the compound is metabolised to one or more toxicologically active metabolites which could make a significant contribution to tissue/organ responses. When measurement of metabolite concentrations in plasma or other bo ...
Electrolytes and metabolic disorder.
... Conduction abnormalities caused by extracellular acidosis (with or without myocardial ischaemia) ...
... Conduction abnormalities caused by extracellular acidosis (with or without myocardial ischaemia) ...
nucleicacidmetabolism
... Resulting bases are sent either into salvage pathways or get degraded and excreted ...
... Resulting bases are sent either into salvage pathways or get degraded and excreted ...
PIPER INDUCED HEPATOTOXICITY IN RATS LONGUM
... Liver, an important organ actively involved in many metabolic functions and is the frequent target for a number of toxicants1.Hepatic damage is associated with distortion of these metabolic functions. The disorders associated with the liver are numerous and varied 2.Liver disease is still a worldwid ...
... Liver, an important organ actively involved in many metabolic functions and is the frequent target for a number of toxicants1.Hepatic damage is associated with distortion of these metabolic functions. The disorders associated with the liver are numerous and varied 2.Liver disease is still a worldwid ...
Chapter 9
... tracheostomy hole and have a strap that goes around the neck. – May not be available in an emergency setting ...
... tracheostomy hole and have a strap that goes around the neck. – May not be available in an emergency setting ...
University of Groningen Interactions between carbohydrate
... synthesizing these three types of substrates. The processes of oxidation and synthesis are ingeniously regulated. This thesis focuses on the interactions between carbohydrate and lipid metabolism, particularly related to the pathophysiology of glycogen storage disease and type II diabetes. Metabolic ...
... synthesizing these three types of substrates. The processes of oxidation and synthesis are ingeniously regulated. This thesis focuses on the interactions between carbohydrate and lipid metabolism, particularly related to the pathophysiology of glycogen storage disease and type II diabetes. Metabolic ...
PHS 398/2590 (Rev. 06/09) - Cardiovascular Research Training
... G. William Wong is currently an Associate Professor in the Department of Physiology and Center for Metabolism and Obesity Research at The Johns Hopkins University School of Medicine. Dr. Wong received his Ph.D. degree from Harvard University, working on innate immunity, followed by post-doctoral tra ...
... G. William Wong is currently an Associate Professor in the Department of Physiology and Center for Metabolism and Obesity Research at The Johns Hopkins University School of Medicine. Dr. Wong received his Ph.D. degree from Harvard University, working on innate immunity, followed by post-doctoral tra ...
Chapter 02 The Chemistry of Biology - College Test bank
... Full file at http://collegetestbank.eu/Test-Bank-Microbiology-4th-Edition-Cowan ASM Objective: 03.02 The interactions of microorganisms among themselves and with their environment are determined by their metabolic abilities (e.g., quorum sensing, oxygen consumption, nitrogen transformations). ASM T ...
... Full file at http://collegetestbank.eu/Test-Bank-Microbiology-4th-Edition-Cowan ASM Objective: 03.02 The interactions of microorganisms among themselves and with their environment are determined by their metabolic abilities (e.g., quorum sensing, oxygen consumption, nitrogen transformations). ASM T ...
Carnitine Overview
... Finally the acyl-CoA is conveyed to the beta-oxidation and fragmented in chains containing two Carbons (acetyl-CoA), which subsequently enter in the Krebs cycle, the Electron Transport Chain, with the final result of energy production ...
... Finally the acyl-CoA is conveyed to the beta-oxidation and fragmented in chains containing two Carbons (acetyl-CoA), which subsequently enter in the Krebs cycle, the Electron Transport Chain, with the final result of energy production ...
Supplementary Materials Metabolic Flux Determination in Perfused
... Palsson 1994). It is generally assumed that the internal metabolites are at pseudo steady state, since metabolic transients are fast compared to environmental changes (Varma and Palsson 1994). Therefore, the mass balance is rewritten as follows: S .v 0 vi 0 ...
... Palsson 1994). It is generally assumed that the internal metabolites are at pseudo steady state, since metabolic transients are fast compared to environmental changes (Varma and Palsson 1994). Therefore, the mass balance is rewritten as follows: S .v 0 vi 0 ...
Bacterial physiological adaptations to contrasting edaphic
... used to define and explore the characteristic genes contributing to the differences between the pH defined soils. Of a total of 6194 annotated genes, 206 and 322 significant functional indicators were found for the low and high pH soils, respectively. A network depicting only strong positive correla ...
... used to define and explore the characteristic genes contributing to the differences between the pH defined soils. Of a total of 6194 annotated genes, 206 and 322 significant functional indicators were found for the low and high pH soils, respectively. A network depicting only strong positive correla ...
De novo lipogenesis in the liver in health and disease: more than
... ABSTRACT Hepatic de novo lipogenesis (DNL) is the biochemical process of synthesising fatty acids from acetyl-CoA subunits that are produced from a number of different pathways within the cell, most commonly carbohydrate catabolism. In addition to glucose which most commonly supplies carbon units fo ...
... ABSTRACT Hepatic de novo lipogenesis (DNL) is the biochemical process of synthesising fatty acids from acetyl-CoA subunits that are produced from a number of different pathways within the cell, most commonly carbohydrate catabolism. In addition to glucose which most commonly supplies carbon units fo ...
FREE Sample Here
... 30. Burning coal produces sulfur dioxide in the atmosphere. When combined with precipitation that falls into bodies of water, this leads to: A. an increase in pH level of the water. B. a greater concentration of OH- ions in the water. C. a decrease in the pH level of the water. D. no change in the p ...
... 30. Burning coal produces sulfur dioxide in the atmosphere. When combined with precipitation that falls into bodies of water, this leads to: A. an increase in pH level of the water. B. a greater concentration of OH- ions in the water. C. a decrease in the pH level of the water. D. no change in the p ...
Full version (PDF file)
... only 0.001 % of total glucose concentration, α-oxoaldehydes are characterized by extremely high chemical activity. They are up to 20,000-fold as reactive as glucose, thus being able to form AGE-structures even at very low concentrations. Physiologically, α-oxoaldehydes react directly with protein te ...
... only 0.001 % of total glucose concentration, α-oxoaldehydes are characterized by extremely high chemical activity. They are up to 20,000-fold as reactive as glucose, thus being able to form AGE-structures even at very low concentrations. Physiologically, α-oxoaldehydes react directly with protein te ...
Effects of Metformin and a Mammalian Target of Rapamycin (mTOR
... of metabolism and cell growth. mTOR is dysregulated in chronic diseases including diabetes and pancreatic cancer. Recent reports indicate that 50% of Pancreatic Ductal Adenocarcinoma (PDAC) patients are diabetic at the time of diagnosis. Furthermore, the anti-diabetic drug, metformin, which indirect ...
... of metabolism and cell growth. mTOR is dysregulated in chronic diseases including diabetes and pancreatic cancer. Recent reports indicate that 50% of Pancreatic Ductal Adenocarcinoma (PDAC) patients are diabetic at the time of diagnosis. Furthermore, the anti-diabetic drug, metformin, which indirect ...
Multiomics of tomato glandular trichomes reveals
... Metabolomics Central metabolites are mostly polar. Therefore, to better understand the connection between primary and secondary metabolism in glandular trichomes, non-targeted profiling for polar and semi-polar metabolites was carried out separately using two LC-MS methods and one GC ...
... Metabolomics Central metabolites are mostly polar. Therefore, to better understand the connection between primary and secondary metabolism in glandular trichomes, non-targeted profiling for polar and semi-polar metabolites was carried out separately using two LC-MS methods and one GC ...
Print - Stroke
... white matter. In referring to table 2, it will be noted that pial vessels possess strong LDH activity, suggesting an active role of the Embden-Meyerhof pathway in the metabolism of these arteriolar circuits. The strong activity of hexose monophosphate shunt enzymes in conjunction with high glycogen ...
... white matter. In referring to table 2, it will be noted that pial vessels possess strong LDH activity, suggesting an active role of the Embden-Meyerhof pathway in the metabolism of these arteriolar circuits. The strong activity of hexose monophosphate shunt enzymes in conjunction with high glycogen ...
Orphan nuclear receptors: therapeutic opportunities in skeletal muscle
... C203–C217, 2006; doi:10.1152/ajpcell.00476.2005.—Nuclear hormone receptors (NRs) are ligand-dependent transcription factors that bind DNA and translate physiological signals into gene regulation. The therapeutic utility of NRs is underscored by the diversity of drugs created to manage dysfunctional ...
... C203–C217, 2006; doi:10.1152/ajpcell.00476.2005.—Nuclear hormone receptors (NRs) are ligand-dependent transcription factors that bind DNA and translate physiological signals into gene regulation. The therapeutic utility of NRs is underscored by the diversity of drugs created to manage dysfunctional ...
Autocatalytic sets in E. coli metabolism
... For the purpose of identifying RAF sets within the E. coli metabolic network, the following transformations of the metabolic network were performed: i) Transport reactions and reactions localized within the E. coli periplasm (except those involved in oxidative phosphorylation) are removed from the n ...
... For the purpose of identifying RAF sets within the E. coli metabolic network, the following transformations of the metabolic network were performed: i) Transport reactions and reactions localized within the E. coli periplasm (except those involved in oxidative phosphorylation) are removed from the n ...
Autocatalytic sets in E. coli metabolism
... For the purpose of identifying RAF sets within the E. coli metabolic network, the following transformations of the metabolic network were performed: i) Transport reactions and reactions localized within the E. coli periplasm (except those involved in oxidative phosphorylation) are removed from the n ...
... For the purpose of identifying RAF sets within the E. coli metabolic network, the following transformations of the metabolic network were performed: i) Transport reactions and reactions localized within the E. coli periplasm (except those involved in oxidative phosphorylation) are removed from the n ...