
Further characterization of the lipoic acid enantiomers
... Most of the world’s supply of SLA is ...
... Most of the world’s supply of SLA is ...
High-dose vitamin therapy stimulates variant enzymes with
... (15), another pioneer in the field of biochemical nutrition, also recognized that higher doses of vitamins may be necessary to accommodate for what he calls biochemical individuality: “Individuality in nutritional needs is the basis for the genetotrophic approach and for the belief that nutrition ap ...
... (15), another pioneer in the field of biochemical nutrition, also recognized that higher doses of vitamins may be necessary to accommodate for what he calls biochemical individuality: “Individuality in nutritional needs is the basis for the genetotrophic approach and for the belief that nutrition ap ...
Aspects of Lipid Metabolism in Crustaceans Department of
... (NIH Training Grant GM-903). We would like to thank members of the staff of the Bermuda Biological Station for Research for their help in collecting G. lateralis and providing facilities for some of the experiments conducted there. ...
... (NIH Training Grant GM-903). We would like to thank members of the staff of the Bermuda Biological Station for Research for their help in collecting G. lateralis and providing facilities for some of the experiments conducted there. ...
Cisplatin in vivo influence on lipid content of chromatin on rat brain
... These lipid quantity alterations in chromatin of brain cells are consequences of deep and multiform transformation of nuclear lipids metabolism caused by antitumor drug cisplatin. It was known for a long time that cell nuclei are sites for active metabolism of lipids, because lipids exchanged differ ...
... These lipid quantity alterations in chromatin of brain cells are consequences of deep and multiform transformation of nuclear lipids metabolism caused by antitumor drug cisplatin. It was known for a long time that cell nuclei are sites for active metabolism of lipids, because lipids exchanged differ ...
Glucose-6-Phosphate Fluorometric Assay Kit
... isomerase to provide cellular energy or carbon skeletons for biosynthesis; 2) be converted into glucose-1-phosphate by phosphoglucomutase, the first step in glycogen synthesis; 3) be metabolized by glucose-6-phosphate dehydrogenase (G6PDH) to NADPH, thereby entering the hexose monophosphate shunt to ...
... isomerase to provide cellular energy or carbon skeletons for biosynthesis; 2) be converted into glucose-1-phosphate by phosphoglucomutase, the first step in glycogen synthesis; 3) be metabolized by glucose-6-phosphate dehydrogenase (G6PDH) to NADPH, thereby entering the hexose monophosphate shunt to ...
Intermediary metabolism
... to be found in free-living bacterivorous nematodes such as C. elegans, which live under mostly temperate conditions. During the 1960s and -70s there was much interest in comparative biochemistry and a great deal of work was done on the metabolism of nematodes, albeit predominantly focusing on parasi ...
... to be found in free-living bacterivorous nematodes such as C. elegans, which live under mostly temperate conditions. During the 1960s and -70s there was much interest in comparative biochemistry and a great deal of work was done on the metabolism of nematodes, albeit predominantly focusing on parasi ...
Sugar Synthesis from CO2 in Escherichia coli
... Cell 166, 1–11, June 30, 2016 ª 2016 The Author(s). Published by Elsevier Inc. 1 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). ...
... Cell 166, 1–11, June 30, 2016 ª 2016 The Author(s). Published by Elsevier Inc. 1 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). ...
Metabolism of Plasma Membrane Lipids in
... synthesis, these bacteria also scavenge and degrade host cell membrane lipids to acetylCoA, via broad families of β-oxidation and other catabolic enzymes, for incorporation into their own metabolic pathways and to fuel cellular processes. The plasma membrane provides the platform for lipid metabolis ...
... synthesis, these bacteria also scavenge and degrade host cell membrane lipids to acetylCoA, via broad families of β-oxidation and other catabolic enzymes, for incorporation into their own metabolic pathways and to fuel cellular processes. The plasma membrane provides the platform for lipid metabolis ...
Metabolomics - Circulation: Cardiovascular Genetics
... routinely used but has motivated the search for more clinically applicable metabolic approaches to cardioprotection. For many decades, even before description of the complete citric acid cycle (CAC), ischemia and hypoxia were recognized to stimulate the degradation of myocardial aspartate and glutam ...
... routinely used but has motivated the search for more clinically applicable metabolic approaches to cardioprotection. For many decades, even before description of the complete citric acid cycle (CAC), ischemia and hypoxia were recognized to stimulate the degradation of myocardial aspartate and glutam ...
- David McDonald, Duke University
... bolic perturbations. In healthy neonates, cord blood concentrations of total acylcarnitines strongly correlated to birth weight, and lower umbilical artery pH caused accumulation of long-chain acylcarnitines [12]. The acylcarnitine profile may additionally be a useful parameter for identifying perina ...
... bolic perturbations. In healthy neonates, cord blood concentrations of total acylcarnitines strongly correlated to birth weight, and lower umbilical artery pH caused accumulation of long-chain acylcarnitines [12]. The acylcarnitine profile may additionally be a useful parameter for identifying perina ...
Unit 2 Homework Booklet [pdf 5MB]
... (c) The turnover number of an enzyme is the number of substrate molecules converted into product by an enzyme in one second when an enzyme is working at its maximum rate. The turnover number for penicillinase is 2000 per second. Calculate the time taken to catalyse the breakdown of one penicillin mo ...
... (c) The turnover number of an enzyme is the number of substrate molecules converted into product by an enzyme in one second when an enzyme is working at its maximum rate. The turnover number for penicillinase is 2000 per second. Calculate the time taken to catalyse the breakdown of one penicillin mo ...
13C MRS: An outstanding tool for metabolic studies
... information as compared with the classical radioactive 14C experiments (8 ). As a counterpart to these advantages, 13C MRS is significantly less sensitive than other conventional metabolic techniques, such as radioactive counting, mass spectrometry, and spectrophotometric or fluorimetric methods. The ...
... information as compared with the classical radioactive 14C experiments (8 ). As a counterpart to these advantages, 13C MRS is significantly less sensitive than other conventional metabolic techniques, such as radioactive counting, mass spectrometry, and spectrophotometric or fluorimetric methods. The ...
Metabolic effects of glutamine on insulin sensitivity
... of proinflammatory cytokines and oxidative stress than insulin or Gln alone. Considering the results of these experimental and human data, the clinical relevance of Gln supplementation becomes self-evident. In particular, considering the elevated number of patients affected by different diseases ass ...
... of proinflammatory cytokines and oxidative stress than insulin or Gln alone. Considering the results of these experimental and human data, the clinical relevance of Gln supplementation becomes self-evident. In particular, considering the elevated number of patients affected by different diseases ass ...
Pathophysiology of lactic acidosis, and its clinical importance after
... the course of the hypoperfusion state and the response to therapeutic interventions. Special Concerns in treatment: Lactic acidosis is observed frequently in patients who are critically ill. Despite a large number of potential etiologies, tissue hyperfusion is by far the most common etiology. •Aggre ...
... the course of the hypoperfusion state and the response to therapeutic interventions. Special Concerns in treatment: Lactic acidosis is observed frequently in patients who are critically ill. Despite a large number of potential etiologies, tissue hyperfusion is by far the most common etiology. •Aggre ...
Fermentation metabolism and its evolution in algae
... has been examined in more detail in Chlamydomonas reinhardtii (Chlamydomonas) than in any other photosynthetic protist. This green alga is metabolically flexible and can sustain energy generation and maintain cellular redox balance under a variety of different environmental conditions. Fermentation m ...
... has been examined in more detail in Chlamydomonas reinhardtii (Chlamydomonas) than in any other photosynthetic protist. This green alga is metabolically flexible and can sustain energy generation and maintain cellular redox balance under a variety of different environmental conditions. Fermentation m ...
Cells Phenotype of Human Tolerogenic Dendritic Glycolytic
... processes require energetic metabolic adaptations important for DC survival, migration, and ultimately the development of pathogenspecific immunity. Understanding the metabolic changes underpinning DC immune function could help develop new strategies for controlling immunogenicity. Studies in mice h ...
... processes require energetic metabolic adaptations important for DC survival, migration, and ultimately the development of pathogenspecific immunity. Understanding the metabolic changes underpinning DC immune function could help develop new strategies for controlling immunogenicity. Studies in mice h ...
Beta-ketothiolase deficiency
... severe hypoglycemia, had elevated lactate level, mild hyperammonemia, and ketonuria on the second day of life. No further acidotic episode occurred. The patient was severely retarded with marked restless, choreathetoid movements, marked hypotonia. In these 2 years, several patients with this disorde ...
... severe hypoglycemia, had elevated lactate level, mild hyperammonemia, and ketonuria on the second day of life. No further acidotic episode occurred. The patient was severely retarded with marked restless, choreathetoid movements, marked hypotonia. In these 2 years, several patients with this disorde ...
Novel regulatory roles of omega-3 fatty acids in metabolic pathways
... Mice fed a high n-3 PUFA diet showed a lower expression of regucalcin compared to mice fed a low n-3 PUFA diet (Table 1). Regucalcin is mainly expressed in rodent liver, and higher expression of regucalcin is linked to metabolic disorders including diabetes and lipid metabolism [38,39]. Regucalcin h ...
... Mice fed a high n-3 PUFA diet showed a lower expression of regucalcin compared to mice fed a low n-3 PUFA diet (Table 1). Regucalcin is mainly expressed in rodent liver, and higher expression of regucalcin is linked to metabolic disorders including diabetes and lipid metabolism [38,39]. Regucalcin h ...
Cholesterol And Sterol Metabolism
... 1/30 Americans of N. European descent are carriers (heterozygous advantage??) Prevalence of SLO is 1:20-60,000 • Predicted prevalence: 1:5-18,000 • Spontaneous abortion • Underdiagnosed ? ...
... 1/30 Americans of N. European descent are carriers (heterozygous advantage??) Prevalence of SLO is 1:20-60,000 • Predicted prevalence: 1:5-18,000 • Spontaneous abortion • Underdiagnosed ? ...
PDF - Circulation Research
... The major fuels of respiration of the heart are fats and carbohydrates. More specifically, energy-providing substrates of the heart include TGs, long-chain FAs (LCFAs), glucose, glycogen, lactate, pyruvate, the ketone bodies acetoacetate and β-hydroxybutyrate, and a variety of amino acids, especiall ...
... The major fuels of respiration of the heart are fats and carbohydrates. More specifically, energy-providing substrates of the heart include TGs, long-chain FAs (LCFAs), glucose, glycogen, lactate, pyruvate, the ketone bodies acetoacetate and β-hydroxybutyrate, and a variety of amino acids, especiall ...
patient assessment - College of Licensed Practical Nurses of Alberta
... nurses (LPNs) receive instruction in this area during their formal education and many have ongoing reinforcement through in-service programs or continuing education offerings. Others have gained significant on the job experiential knowledge and skill, while yet others have advanced their skill throu ...
... nurses (LPNs) receive instruction in this area during their formal education and many have ongoing reinforcement through in-service programs or continuing education offerings. Others have gained significant on the job experiential knowledge and skill, while yet others have advanced their skill throu ...
Salcedo-SoraAndMcAul
... range of infectious diseases.5 However, due to increasing drug resistance their efficacy has been compromised forcing in some cases the withdrawal of formulations of antifolates unless they are combined with a further antimicrobial that works through a different mechanism of action.6 Furthermore, th ...
... range of infectious diseases.5 However, due to increasing drug resistance their efficacy has been compromised forcing in some cases the withdrawal of formulations of antifolates unless they are combined with a further antimicrobial that works through a different mechanism of action.6 Furthermore, th ...
Metabolic and Developmental Adaptations of
... tubers and developing seeds, internal oxygen concentrations can fall to relatively low levels, leading to adaptive responses such as decreased respiration, decreased adenylate energy state and inhibition of various biosynthetic processes (Geigenberger, 2003b). Previous work to analyze the role of ad ...
... tubers and developing seeds, internal oxygen concentrations can fall to relatively low levels, leading to adaptive responses such as decreased respiration, decreased adenylate energy state and inhibition of various biosynthetic processes (Geigenberger, 2003b). Previous work to analyze the role of ad ...
REVIEWS Perioperative use of metformin in cardiac surgery 723 Edmundas Širvinskas
... treatment with metformin or insulin was very effective for glycemic control and had a positive impact on the rate of vascular complications. Moreover, in obese patients, metformin significantly reduced mortality from cardiac causes; no episodes of hypoglycemia and weight gain were documented in these ...
... treatment with metformin or insulin was very effective for glycemic control and had a positive impact on the rate of vascular complications. Moreover, in obese patients, metformin significantly reduced mortality from cardiac causes; no episodes of hypoglycemia and weight gain were documented in these ...