The Puzzle of the Krebs Citric Acid Cycle: Assembling the Pieces of
... computer program (Serratosa and Xicart 1990) was used to analyze some possible pathways. This program was designed as a heuristic tool to search for the most accurate reaction sequences in organic synthesis; it gives a retrosynthetic analysis generating the possible intermediate precursors of a give ...
... computer program (Serratosa and Xicart 1990) was used to analyze some possible pathways. This program was designed as a heuristic tool to search for the most accurate reaction sequences in organic synthesis; it gives a retrosynthetic analysis generating the possible intermediate precursors of a give ...
Alternative routes of acetyl-CoA synthesis identified
... oleaginous strains. These proteins were designated ‘orthologous oleaginous proteins’ (Table 1). Using information from the KEGG database, the orthologous oleaginous sequences were categorized into five classes (Table 1), including genes involved in metabolism (19.6 % of total orthologous oleaginous ...
... oleaginous strains. These proteins were designated ‘orthologous oleaginous proteins’ (Table 1). Using information from the KEGG database, the orthologous oleaginous sequences were categorized into five classes (Table 1), including genes involved in metabolism (19.6 % of total orthologous oleaginous ...
Full Text - Journal of The Royal Society Interface
... interact with any other cytoplasmic protein, catalyse reactions with any of the several hundreds of metabolites or otherwise interact with any important physiological process. In other words, it is rather difficult to predict the effect of expanding the cellular genome, in any case quantitatively, bu ...
... interact with any other cytoplasmic protein, catalyse reactions with any of the several hundreds of metabolites or otherwise interact with any important physiological process. In other words, it is rather difficult to predict the effect of expanding the cellular genome, in any case quantitatively, bu ...
Magnesium liquid - Pure Encapsulations
... metabolism and lipid metabolism. A meta-analysis of 20 randomized trials suggests that it also promotes healthy systolic and diastolic function. In addition, magnesium supports healthy glucose metabolism. In one 15-year study involving 4,637 young adults, higher intakes of magnesium were associated ...
... metabolism and lipid metabolism. A meta-analysis of 20 randomized trials suggests that it also promotes healthy systolic and diastolic function. In addition, magnesium supports healthy glucose metabolism. In one 15-year study involving 4,637 young adults, higher intakes of magnesium were associated ...
DOC-file of additional text
... apparent duplicates (Supplementary Table 12). The presence of reactions in endosymbionts is inferred from gene orthology in combination with known enzymatic functions in E.coli. Detailed results of all simulations are in Supplementary Table 13. ...
... apparent duplicates (Supplementary Table 12). The presence of reactions in endosymbionts is inferred from gene orthology in combination with known enzymatic functions in E.coli. Detailed results of all simulations are in Supplementary Table 13. ...
ab109902 – Pyruvate dehydrogenase (PDH) Enzyme Activity
... calculate the amount (%) of PDH activity that is inhibited by phosphorylation at the time of immunocapture. Note that PDH activity can also be inhibited by other factors, such as oxidative stress, that are not affected by phosphorylation state. ...
... calculate the amount (%) of PDH activity that is inhibited by phosphorylation at the time of immunocapture. Note that PDH activity can also be inhibited by other factors, such as oxidative stress, that are not affected by phosphorylation state. ...
Matrix-assisted Laser Desorption/Ionization Mass Spectrometry in
... serves to increase the amount of time, t, ions need to reach the detector while reducing their KE distribution, thereby reducing the temporal distribution t. Since resolution is defined by the mass of a peak divided by the width of a peak or m/m (or t/t since m is related to t), increasing t and ...
... serves to increase the amount of time, t, ions need to reach the detector while reducing their KE distribution, thereby reducing the temporal distribution t. Since resolution is defined by the mass of a peak divided by the width of a peak or m/m (or t/t since m is related to t), increasing t and ...
13C-fluxomics
... • Identification of (novel) pathways, enzymes • Linear pathways, cycles, reaction reversibilty • Compartmentation, channeling ...
... • Identification of (novel) pathways, enzymes • Linear pathways, cycles, reaction reversibilty • Compartmentation, channeling ...
32_Metabolism of ammonia. Biosynthesis of urea and its disorders
... Nitrogen is then transferred to pyruvate to form alanine, which is released into the blood. ...
... Nitrogen is then transferred to pyruvate to form alanine, which is released into the blood. ...
Inhibitors are structural analogs of true substrate
... A 49-year-old driver complains about unbearable constricting pain behind the breastbone irradiating to the neck. The pain arose 2 hours ago. Objectively: the patient’s condition is grave, he is pale, heart tones are decreased. Laboratory studies revealed high activity of creatine kinase and LDH1. Wh ...
... A 49-year-old driver complains about unbearable constricting pain behind the breastbone irradiating to the neck. The pain arose 2 hours ago. Objectively: the patient’s condition is grave, he is pale, heart tones are decreased. Laboratory studies revealed high activity of creatine kinase and LDH1. Wh ...
Physiological characterisation of plants with - diss.fu
... used: wild type, black circles; RL40, white triangles; RL25, black squares. Values are presented as mean ± SE of determination on five individual plants per line; an asterisk indicates values that were determined by the t test to be significantly different (P< 0.05) from the wild type. ...
... used: wild type, black circles; RL40, white triangles; RL25, black squares. Values are presented as mean ± SE of determination on five individual plants per line; an asterisk indicates values that were determined by the t test to be significantly different (P< 0.05) from the wild type. ...
LDN research on MS in Scotland Dr Tom Gilhooly, USC 4th Annual
... Correlation NO levels and severity of disability/MRI appearance at 3 yrs 2008 – nitrosative stress assoc with sustained disability in MS ...
... Correlation NO levels and severity of disability/MRI appearance at 3 yrs 2008 – nitrosative stress assoc with sustained disability in MS ...
ALLOMETRIC SCALING IN CENTRARCHID FISH Enzyme Levels in Muscles
... body size. Maximal metabolic rate (MMR) allometrically scales with body mass with greater b values than basal metabolic rate. MMR is defined as “the energy needs of locomotor activity at its sustainable maximum during a run” (Weibel et al. 2004). Weibel and colleagues (2004) investigated MMR in 34 m ...
... body size. Maximal metabolic rate (MMR) allometrically scales with body mass with greater b values than basal metabolic rate. MMR is defined as “the energy needs of locomotor activity at its sustainable maximum during a run” (Weibel et al. 2004). Weibel and colleagues (2004) investigated MMR in 34 m ...
News release
... Amersham Biosciences, the life sciences business of Amersham plc (LSE, NYSE, OSE: AHM), is a world leader in developing and providing integrated systems and solutions for disease research, drug development and manufacture. Our systems are used to uncover the function of genes and proteins, for the d ...
... Amersham Biosciences, the life sciences business of Amersham plc (LSE, NYSE, OSE: AHM), is a world leader in developing and providing integrated systems and solutions for disease research, drug development and manufacture. Our systems are used to uncover the function of genes and proteins, for the d ...
Analysis of structural robustness of metabolic
... metabolism cannot be seen as easily as in these examples. To understand robustness in complex systems such as metabolic networks, theoretical tools are needed [4 –8]. Studies on robustness have manifold applications. In biotechnology, specific enzymes can be knocked out to suppress futile cycles. Fo ...
... metabolism cannot be seen as easily as in these examples. To understand robustness in complex systems such as metabolic networks, theoretical tools are needed [4 –8]. Studies on robustness have manifold applications. In biotechnology, specific enzymes can be knocked out to suppress futile cycles. Fo ...
Patterns of prokaryotic lateral gene transfers affecting parasitic
... A range of different methods have been used to detect LGTs, with varying degrees of agreement between methods [19]. Detailed phylogenetic analyses are probably the most rigorous approach [19], but can be time-consuming for large numbers of genes, requiring a trade-off between analytical sophisticati ...
... A range of different methods have been used to detect LGTs, with varying degrees of agreement between methods [19]. Detailed phylogenetic analyses are probably the most rigorous approach [19], but can be time-consuming for large numbers of genes, requiring a trade-off between analytical sophisticati ...
Patterns of prokaryotic lateral gene transfers affecting parasitic
... A range of different methods have been used to detect LGTs, with varying degrees of agreement between methods [19]. Detailed phylogenetic analyses are probably the most rigorous approach [19], but can be time-consuming for large numbers of genes, requiring a trade-off between analytical sophisticati ...
... A range of different methods have been used to detect LGTs, with varying degrees of agreement between methods [19]. Detailed phylogenetic analyses are probably the most rigorous approach [19], but can be time-consuming for large numbers of genes, requiring a trade-off between analytical sophisticati ...
From CO2 to cell: energetic expense of creating biomass using the
... is a competitive substrate with CO2 for RubisCO and results in a wasteful oxygenase reaction. Aerobic cells must minimize the chances of the oxygenase reaction, which results in the loss of a carbon dioxide molecule as well as the consumption of ATP to regenerate RuBP (Tabita et al. 2008). The rCAC ...
... is a competitive substrate with CO2 for RubisCO and results in a wasteful oxygenase reaction. Aerobic cells must minimize the chances of the oxygenase reaction, which results in the loss of a carbon dioxide molecule as well as the consumption of ATP to regenerate RuBP (Tabita et al. 2008). The rCAC ...
Translating the basic knowledge of mitochondrial functions to
... the early energetic response of the heart to metabolic therapy, and this approach may provide a surrogate marker of long-term prognostic effects. ROLE OF L-CARNITINE IN METABOLIC THERAPY ...
... the early energetic response of the heart to metabolic therapy, and this approach may provide a surrogate marker of long-term prognostic effects. ROLE OF L-CARNITINE IN METABOLIC THERAPY ...
Title Metabolism of fluoroorganic compounds in microorganisms
... fluorocyclohexadiene intermediate by GC-MS and 19F NMR analyses of culture supernatants. A small number of reports describe investigations on the bacterial transformation of benzoate and catechol substituted with a trifluoromethyl group, which the most widely used fluorinated moiety in pharmaceutica ...
... fluorocyclohexadiene intermediate by GC-MS and 19F NMR analyses of culture supernatants. A small number of reports describe investigations on the bacterial transformation of benzoate and catechol substituted with a trifluoromethyl group, which the most widely used fluorinated moiety in pharmaceutica ...
Syllabus 2015/2016!
... Identify and describe the major functions and structures of the male reproductive system. ! Recognize, define, spell, and pronounce the terms related to the pathology and diagnostic and treatment procedures of the male reproductive system. ! Identify and describe the major functions and structures o ...
... Identify and describe the major functions and structures of the male reproductive system. ! Recognize, define, spell, and pronounce the terms related to the pathology and diagnostic and treatment procedures of the male reproductive system. ! Identify and describe the major functions and structures o ...
of Conformationally constrained chemotactic peptide analogs R.J.
... differ only in the nature of the acceptor C = O group. Theoretical analysis of Aib residues suggests that the differences in energies for the ,&turn (4 f60", f20", 3 - f 30" f20"; i+ 2 residue in type III(1) or I I I f ( I f )and type I1 or 11' &turns) and a y-turn conformation (4 & 80'3- f80") is 3 ...
... differ only in the nature of the acceptor C = O group. Theoretical analysis of Aib residues suggests that the differences in energies for the ,&turn (4 f60", f20", 3 - f 30" f20"; i+ 2 residue in type III(1) or I I I f ( I f )and type I1 or 11' &turns) and a y-turn conformation (4 & 80'3- f80") is 3 ...
Small-molecule metabolism: an enzyme mosaic
... Fig. 3. Fucose, rhamnose and L-arabinose catabolism. (a) Fucose and rhamnose. A superpathway exists in EcoCyc that consists of the fucose and rhamnose catabolism subpathways. An example of serial recruitment and of ‘parallel’ enzymes is shown (boxed). Serial recruitment has occurred because fucK (L- ...
... Fig. 3. Fucose, rhamnose and L-arabinose catabolism. (a) Fucose and rhamnose. A superpathway exists in EcoCyc that consists of the fucose and rhamnose catabolism subpathways. An example of serial recruitment and of ‘parallel’ enzymes is shown (boxed). Serial recruitment has occurred because fucK (L- ...
Epidemiology - PHG Foundation
... The prevalence of IMDs is increasing because of some of these factors, as well as improved treatment and survival; this has implications for the provision and planning of appropriate clinical services for patients with IMDs. One of the major problems is that UK-specific data are very limited. Given ...
... The prevalence of IMDs is increasing because of some of these factors, as well as improved treatment and survival; this has implications for the provision and planning of appropriate clinical services for patients with IMDs. One of the major problems is that UK-specific data are very limited. Given ...
Lipid Transport & Storage
... Brown adipose tissue is involved in metabolism particularly at times when heat generation is necessary ...
... Brown adipose tissue is involved in metabolism particularly at times when heat generation is necessary ...