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Marks` Basic Medical Biochemistry, 2e
Marks` Basic Medical Biochemistry, 2e

... A well-organized icon system quickly guides you to the information you need. Marginal notes provide brief clinical correlations, short questions and answers, and interesting asides. Each chapter ends with “Biochemical Comments” and “Clinical Comments”; both sections summarize the key biochemical and ...
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... substrate-level phosphorylation Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Acid-base balance
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... excretion of acid or alkali by the body, resulting in a stable concentration of H+ in body fluids An adult normally produces 1-2 mEq/kg/24 hr of hydrogen ions. Children produce 2-3 mEq/kg/24 hr of hydrogen ions. The 3 principal sources of hydrogen ions:  Dietary protein metabolism,  Incomplete met ...
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... chloride, chromium, copper, iron, lead magnesium, manganese, phosphorous, potassium, selenium, sodium and zinc. These mineral elements may be associated with the various vital processes in the body. Preliminary phytochemical screening of successive extracts of fruit reveals the presence of secondary ...
Role of Carnitine in Lipid Metabolism
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... fatty acid synthesis. Many questions remain concerning the regulation of the carnitine transport process during the normal physiological cycles of feasting and fasting as well as during a variety of disease states. Since the first description of human carnitine deficiency in 1973 (5), many camitine ...
THE USE OF TBE ETHANOL PATHWAY IN GOLDFISH CARASSIUS
THE USE OF TBE ETHANOL PATHWAY IN GOLDFISH CARASSIUS

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... included hydroquinone, muconic acid, and phenylmercapturic acid, which share benzene oxide as a common intermediate, demonstrating that the metabolic pathway of DAAB is similar to that of benzene. In studies with human liver slices, DAAB was reduced to benzene and aniline (Mathews and De Costa 1999) ...
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... glucose in glucose-6-phosphatase deficiency). The biodisposability and intestinal absorption of several nutrients, such as vitamins or trace éléments, may be very différent between synthetic diets and normal foodstuffs. Apart from the main effects intended by the treatment, it is important to be con ...
Cfe Higher Biology Metabolism and Survival
Cfe Higher Biology Metabolism and Survival

... • Enzyme reactions do not take place in isolation but in pathways. • Many of these pathways are reversible, but some are not. • Where pathways are irreversible, or energetically unfavourable, alternative pathways are usually available. • Pathways are either catabolic, which is where there is an over ...
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... and students who contributed to the SCHOLAR programme and who evaluated these materials. Grateful acknowledgement is made for permission to use the following material in the ...
Cfe Higher Biology Metabolism and Survival
Cfe Higher Biology Metabolism and Survival

... • Enzyme reactions do not take place in isolation but in pathways. • Many of these pathways are reversible, but some are not. • Where pathways are irreversible, or energetically unfavourable, alternative pathways are usually available. • Pathways are either catabolic, which is where there is an over ...
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... analysis is performed only occasionally in forensic casework. The identification and individualization of urine samples does not pose a medico-legal concern, unlike that of blood, saliva, or sperm (Sołtyszewski et al., 2006). Although the collection of urinary samples is straightforward, storage and ...
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Eurofins Legionella PCR (Polymerase Chain Reaction) Technical
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... result as Legionella bacteria are slow growing in the laboratory. A further 3 days are required for confirmation in the case of suspect colonies being identified on the agar plates. In contrast, the Legionella PCR technique is able to arrive at a confirmed positive or negative result in 24 hours. Th ...
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Chemical Characterization of Polar Species in Colombian

... Thousands of tons of vacuum residua are generated annually by refineries. These can be better exploited if their composition and chemical behavior is known, allowing to develop appropriated conversion processes (Müller at al., 2005). The conventional characterization of this type of complex samples ...
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Pharmacometabolomics

Pharmacometabolomics, also known as pharmacometabonomics, is a field which stems from metabolomics, the quantification and analysis of metabolites produced by the body. It refers to the direct measurement of metabolites in an individual’s bodily fluids, in order to predict or evaluate the metabolism of pharmaceutical compounds, and to better understand the pharmacokinetic profile of a drug. Alternatively, pharmacometabolomics can be applied to measure metabolite levels following the administration of a pharmaceutical compound, in order to monitor the effects of the compound on certain metabolic pathways(pharmacodynamics). This provides detailed mapping of drug effects on metabolism and the pathways that are implicated in mechanism of variation of response to treatment. In addition, the metabolic profile of an individual at baseline (metabotype) provides information about how individuals respond to treatment and highlights heterogeneity within a disease state. All three approaches require the quantification of metabolites found in bodily fluids and tissue, such as blood or urine, and can be used in the assessment of pharmaceutical treatment options for numerous disease states.
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