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... Hence, cellulose, hemicelluloses, and lignin, collectively known as lignocellulosic biomass, will become an important raw material for the biorefinery. Cellulose is an unbranched, crystalline microfibril constructed from 7,000 to 15,000 a-D glucose molecules. Embedded in hemicelluloses it acts as re ...
... Hence, cellulose, hemicelluloses, and lignin, collectively known as lignocellulosic biomass, will become an important raw material for the biorefinery. Cellulose is an unbranched, crystalline microfibril constructed from 7,000 to 15,000 a-D glucose molecules. Embedded in hemicelluloses it acts as re ...
Amino Acids Metabolism: Disposal of Nitrogen.
... -This toxic ammonia is converted into amino group of glutamine that transported to liver or kidneys. - Glutamine: non-toxic transport form of NH4+ and also source of amino group in many biosynthesis reactions. - The amide nitrogen of glutamine is released as ammonia only in liver and kidney’s mitoch ...
... -This toxic ammonia is converted into amino group of glutamine that transported to liver or kidneys. - Glutamine: non-toxic transport form of NH4+ and also source of amino group in many biosynthesis reactions. - The amide nitrogen of glutamine is released as ammonia only in liver and kidney’s mitoch ...
Proton NMR chemical shifts and coupling constants for brain
... where model spectra are generated for each metabolite by computer simulation to obtain a list of the relative frequencies, phases, and amplitudes of all resonances for each metabolite. This procedure requires information on the chemical shifts of each multiplet group, J-couplings, field strength, an ...
... where model spectra are generated for each metabolite by computer simulation to obtain a list of the relative frequencies, phases, and amplitudes of all resonances for each metabolite. This procedure requires information on the chemical shifts of each multiplet group, J-couplings, field strength, an ...
Cytochrome P450 gene test to establish the correct warfarin dose in
... currently in the blood. Item number 66812: “Quantitation by any method or methods, in blood, urine or other body fluid, of a drug being used therapeutically by the patient from whom the specimen was taken”, fee $35.45. To identify patients who may metabolise warfarin poorly, a molecular assay must ...
... currently in the blood. Item number 66812: “Quantitation by any method or methods, in blood, urine or other body fluid, of a drug being used therapeutically by the patient from whom the specimen was taken”, fee $35.45. To identify patients who may metabolise warfarin poorly, a molecular assay must ...
Determination of 17 AQC derivatized Amino acids in
... highly reactive amine derivatization reagent can be used in an easy one step procedure.6 The compound reacts with amino acids to form stable urea derivatives which are readily amenable for analysis by reversed phase HPLC. Primary and secondary amino acids are derivatized quickly and they are stable ...
... highly reactive amine derivatization reagent can be used in an easy one step procedure.6 The compound reacts with amino acids to form stable urea derivatives which are readily amenable for analysis by reversed phase HPLC. Primary and secondary amino acids are derivatized quickly and they are stable ...
Using NMR Metabolomics to Investigate Tricarboxylic Acid Cycle
... necessitates the need for changes in the expression of genes coding for enzymes required for growth in the new environment. This environmental adaptation often includes activating transcription of virulence genes; hence, most virulence genes are regulated by environmental and nutritional signals (2) ...
... necessitates the need for changes in the expression of genes coding for enzymes required for growth in the new environment. This environmental adaptation often includes activating transcription of virulence genes; hence, most virulence genes are regulated by environmental and nutritional signals (2) ...
Consequences of biotransformation of plant secondary metabolites
... relatively nontoxic PSMs would eventually produce nonspecific adverse effects at high concentrations. Enzyme systems have evolved to enable animals to transform dietary lipophilic compounds into water-soluble, excretable metabolites (Williams, 1959; Scheline, 1991; Sipes and Gandolfi, 1991). The pri ...
... relatively nontoxic PSMs would eventually produce nonspecific adverse effects at high concentrations. Enzyme systems have evolved to enable animals to transform dietary lipophilic compounds into water-soluble, excretable metabolites (Williams, 1959; Scheline, 1991; Sipes and Gandolfi, 1991). The pri ...
Deriving phylogenetic trees from the similarity analysis of metabolic
... result in phylogenetic trees with the wrong topology. The recently completed sequences of several organism genomes provide an enormous amount of data with which to address some of these problems. Phylogenetic analysis can also be performed using the whole genome [14, 29], leading to more precise stu ...
... result in phylogenetic trees with the wrong topology. The recently completed sequences of several organism genomes provide an enormous amount of data with which to address some of these problems. Phylogenetic analysis can also be performed using the whole genome [14, 29], leading to more precise stu ...
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats
... different plasma concentrations of several amino acids between the groups, with lower methionine and higher glycine and serine in animals fed CP. Methionine serve as the precursor of the universal methyl donor S-adenosylmethionine (SAM), used in numerous methylation reactions throughout the body, wi ...
... different plasma concentrations of several amino acids between the groups, with lower methionine and higher glycine and serine in animals fed CP. Methionine serve as the precursor of the universal methyl donor S-adenosylmethionine (SAM), used in numerous methylation reactions throughout the body, wi ...
Synthetic biology for engineering acetyl coenzyme a
... can be used as biofuels, e.g., farnesene, pharmaceuticals, e.g., the antimalarial drug artemisinic acid, perfumes, and fine fragrances, e.g., santalene, and nutraceutical ingredients, e.g., -carotene and lycopene. ● Sterols such as ergosterol that can be used as dietary supplements. ● Polyketides t ...
... can be used as biofuels, e.g., farnesene, pharmaceuticals, e.g., the antimalarial drug artemisinic acid, perfumes, and fine fragrances, e.g., santalene, and nutraceutical ingredients, e.g., -carotene and lycopene. ● Sterols such as ergosterol that can be used as dietary supplements. ● Polyketides t ...
Lecture 03, NEW - terpenes + polyketides
... - provides a huge number of potential 3D structures - high degree of biological activity (3) Pathways can be elucidated using labeled precursors, such as mevalonate with a 13C at position 2 - carbon NMR experiments reveal where the label ends up in the completed molecule ...
... - provides a huge number of potential 3D structures - high degree of biological activity (3) Pathways can be elucidated using labeled precursors, such as mevalonate with a 13C at position 2 - carbon NMR experiments reveal where the label ends up in the completed molecule ...
Metabolic flux profiling of recombinant protein secreting Pichia
... Growth and product formation of recombinant P. pastoris strains There are only few physiological studies on the potential impact of recombinant protein production on the core metabolism of P. pastoris, particularly for those cases where the product is secreted [9, 15]. The aim of our study was to q ...
... Growth and product formation of recombinant P. pastoris strains There are only few physiological studies on the potential impact of recombinant protein production on the core metabolism of P. pastoris, particularly for those cases where the product is secreted [9, 15]. The aim of our study was to q ...
Intact PTH
... Biological activity resides in the N-terminal portion of the molecule (1–34). Metabolism is via the liver and kidneys. PTH is secreted by the parathyroid gland in response to a decrease in serum ionised calcium concentration. PTH acts to increase serum calcium and decrease phosphate and bicarbonate. ...
... Biological activity resides in the N-terminal portion of the molecule (1–34). Metabolism is via the liver and kidneys. PTH is secreted by the parathyroid gland in response to a decrease in serum ionised calcium concentration. PTH acts to increase serum calcium and decrease phosphate and bicarbonate. ...
Mapping Post-Transcriptional Modifications onto Transfer
... platforms for mapping tRNA modifications, direct analysis of intact tRNAs is typically beyond the capabilities of common mass spectrometry instrumentation requiring specialized high‐end capabilities [43]. Thus, an analytical strategy was developed by the McCloskey group, which utilizes ba ...
... platforms for mapping tRNA modifications, direct analysis of intact tRNAs is typically beyond the capabilities of common mass spectrometry instrumentation requiring specialized high‐end capabilities [43]. Thus, an analytical strategy was developed by the McCloskey group, which utilizes ba ...
- BioMed Central
... microarray technology allows for the investigation of all genes of an organism under various conditions, resulting in the generation of a massive amount of expression data. One of the greatest challenge we are faced with is to then analyse the data as a whole and extract the meaningful relationships ...
... microarray technology allows for the investigation of all genes of an organism under various conditions, resulting in the generation of a massive amount of expression data. One of the greatest challenge we are faced with is to then analyse the data as a whole and extract the meaningful relationships ...
Detection of cis-trans Isomers of a Synthetic Peptide Fragment of
... and “heated” samples can be understood if (in this example) the retention time of an isomer increases with the energy of that isomer. The NMR studies confirmed these findings and also yielded two new pieces of information. The existence of multiple forms of the peptide depended on the state of ioniz ...
... and “heated” samples can be understood if (in this example) the retention time of an isomer increases with the energy of that isomer. The NMR studies confirmed these findings and also yielded two new pieces of information. The existence of multiple forms of the peptide depended on the state of ioniz ...
FACTEURS DE COMPLEXITE DANS L’ETUDE DES …
... The role of fipronil metabolic pathways Plasma concentrations (ng/mL) ...
... The role of fipronil metabolic pathways Plasma concentrations (ng/mL) ...
Integrative Physiology Cardiac-Specific Deletion of Acetyl CoA
... normalized to protein concentration. For global metabolite profiling, ventricular tissue was extracted in 2:1 chloroform: methanol and analyzed by GC⫻GC-TOFMS.31 The previously developed F-ratio method was used to analyze all samples at each mass channel. Detection of additional metabolic features w ...
... normalized to protein concentration. For global metabolite profiling, ventricular tissue was extracted in 2:1 chloroform: methanol and analyzed by GC⫻GC-TOFMS.31 The previously developed F-ratio method was used to analyze all samples at each mass channel. Detection of additional metabolic features w ...
References - The University of New Mexico
... While such simplified expressions of chemical reactions are conceptually easy to comprehend, the reality of the biochemistry of H+ balance in muscle energy metabolism is far more complex. All of the metabolites of the phosphagen and glycolytic energy systems have one or multiple sites for ionization ...
... While such simplified expressions of chemical reactions are conceptually easy to comprehend, the reality of the biochemistry of H+ balance in muscle energy metabolism is far more complex. All of the metabolites of the phosphagen and glycolytic energy systems have one or multiple sites for ionization ...
Emergency Care and Treatment (ECAT)
... more senior health care providers, thus helping to provide informed and concerted patient care. All emergency response personnel likely to be first at the scene of an incident, such as police, firefighters or defense force will benefit from this course. It is well-established that quick and appropri ...
... more senior health care providers, thus helping to provide informed and concerted patient care. All emergency response personnel likely to be first at the scene of an incident, such as police, firefighters or defense force will benefit from this course. It is well-established that quick and appropri ...
Cerebral Energy Metabolism in Hepatic Encephalopathy and
... Changes in Glucose Utilization Cerebral metabolic rate for glucose (CMRglc ) has consistently been reported to be decreased in patients with chronic HE (see review by Hazell and Butterworth, 1999), suggesting that hypometabolism could contribute to the neuropsychiatric symptoms commonly observed in ...
... Changes in Glucose Utilization Cerebral metabolic rate for glucose (CMRglc ) has consistently been reported to be decreased in patients with chronic HE (see review by Hazell and Butterworth, 1999), suggesting that hypometabolism could contribute to the neuropsychiatric symptoms commonly observed in ...
Biosketch - NC State University
... 5. Muoio DM, Dohm GL, Tapscott EB and Coleman RA. Counter-regulatory effects of leptin and insulin in muscles from lean and obese ob/ob mice. American Journal of Physiology. 1999 276; E913-E921. 6. Muoio DM, Seefeld K, Witters LA and Coleman RA. AMP-activated kinase reciprocally regulates triacylgly ...
... 5. Muoio DM, Dohm GL, Tapscott EB and Coleman RA. Counter-regulatory effects of leptin and insulin in muscles from lean and obese ob/ob mice. American Journal of Physiology. 1999 276; E913-E921. 6. Muoio DM, Seefeld K, Witters LA and Coleman RA. AMP-activated kinase reciprocally regulates triacylgly ...
Effect of LIVNITRO on Protein Anabolism
... LivNitro+ group was -0.11 ± 0.14 and 0.01 ± 0.11 in placebo group with significance of p<0.0001 between the group. On Day 18 the fall as compared to baseline in LivNitro+ group was -0.06 ± 0.17 and 0.05 ± 0.22 in placebo group with significance of p<0.0235. On Day 28 the fall as compared to baseline ...
... LivNitro+ group was -0.11 ± 0.14 and 0.01 ± 0.11 in placebo group with significance of p<0.0001 between the group. On Day 18 the fall as compared to baseline in LivNitro+ group was -0.06 ± 0.17 and 0.05 ± 0.22 in placebo group with significance of p<0.0235. On Day 28 the fall as compared to baseline ...
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... from litter-mates were allowed to equilibrate for 1 h in oxygenated KrebsRinger bicarbonate solution which contained 5 x 10~ 3 M glucose. The inhibitor was added to the medium after one hour of equilibration. One chamber was supplied with oxygen and the other an anaerobic gas phase consisting of 95 ...
... from litter-mates were allowed to equilibrate for 1 h in oxygenated KrebsRinger bicarbonate solution which contained 5 x 10~ 3 M glucose. The inhibitor was added to the medium after one hour of equilibration. One chamber was supplied with oxygen and the other an anaerobic gas phase consisting of 95 ...