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LIMS for the Masses - University of Alberta
LIMS for the Masses - University of Alberta

... of the time-related “total” metabolic response of vertebrates to pathophysiological (nutritional, xenobiotic, surgical or toxic ...
Fungal Metabolism
Fungal Metabolism

... 4 Intermediate in biosynthesis of compound. Secondary metabolites; Organic compounds , with low molecular weight ,which are not essential for fungal growth but their natural production have certain significances. Furthermore, secondary metabolites are derived from a few common biosynthetic pathways ...
research abstract form
research abstract form

... Obesity is a chronic condition that primarily develops from an increase in body fat in the form of white adipose tissue (WAT) mass. The resulting adiposity is a risk factor for many diseases, including type 2 diabetes (T2D), cardiovascular diseases, and some forms of cancer. White adipocytes, the ma ...
The non-proteic extrusive secondary metabolites in ciliated protists F
The non-proteic extrusive secondary metabolites in ciliated protists F

... functional. The chemical nature of protists’ extrusive compounds characterized to date is extremely variable, including proteins, carbohydrates, lipids, and dozens of additional classes of secondary metabolites. However an increasing set of data are now available for particular group of protists, th ...
ULLA Summer School 2005
ULLA Summer School 2005

... accurate measurement and identification of complex mixtures of proteins and peptides can be made using highresolution protein separation techniques and identification by mass spectrometry. This allows an insight into the expression of proteins in complex biological systems under a variety of circums ...
Celem projektu była identyfikacja biomarkerów uzależnienia od
Celem projektu była identyfikacja biomarkerów uzależnienia od

... drug dependence. The research was focused on the identification of molecular mechanisms involved in these processes and clarification of the role of particular proteins in morphine dependence. Project puts special emphasis on phosphoproteins, and in general on phosphorylation, as a main mechanism in ...
ppt - University of Illinois Urbana
ppt - University of Illinois Urbana

... – http://www.expasy.org/cgi-bin/show_thumbnails.pl – http://www.expasy.org/cgi-bin/show_thumbnails.pl?2 – http://www.genome.ad.jp/kegg/pathway.html ...
Taícia P. Fill1, Edson Rodrigues Filho1
Taícia P. Fill1, Edson Rodrigues Filho1

... endophytic fungus Penicillium brasilianum which present important antiparasitic and antibacteriological activities[1]. In the present work, the biosynthesis of these compounds was evaluated through the addition of labeled precursors in the culture medium. In this sense, 13C Isotopically labeled phen ...
Separation Technique for the Determination of Highly Polar
Separation Technique for the Determination of Highly Polar

... Received: 8 June 2012; in revised form: 31 July 2012 / Accepted: 6 August 2012 / Published: 16 August 2012 ...
Achieving the highest quality data at the lowest levels in
Achieving the highest quality data at the lowest levels in

... Figure 2. Comprehensive structural elucidation of the m/z 458 metabolite aided by annotation of low level fragments in the elevated energy data (Annotation shown includes: m/z, mass error (Da), and proposed metabolite name). ...
toxicology-news-48-opioid-metabolism-lm
toxicology-news-48-opioid-metabolism-lm

... profiles of the drugs would always consist of: the parent compound, N-methylation metabolites, Omethylation metabolites, and other further brokendown metabolites. From previous studies [1], urinary profiles for hydrocodone after a single dose at 72 hours were: unchanged drug (12%), norhydrocodone (5 ...
Mass Spectrometry - University of Exeter
Mass Spectrometry - University of Exeter

... “Current Examples of Research“ 15:30 Tea/Coffee in Geoffrey Pope Informal opportunity to discuss your research and how MS may help Tour of the facility 16:30 Finish ...
Metabolism_PartII Group work
Metabolism_PartII Group work

... o Fermentation  Part B: Now label on each diagram how the harvested energy is stored during each catabolic process.  ATP • Substrate-level phosphorylation and/or • Oxidative phosphorylation  Proton motive force • Electron transport chain o Oxidation-reduction (redox) reactions o Active transport ...
Proteomics and Mass Spectrometry April 23
Proteomics and Mass Spectrometry April 23

... also in the analysis of complex mixtures (e.g. protein complexes, proteins in organelles or even entire cells). With recent developments in mass spectrometry, but also in separation science (such as two-dimensional electrophoresis and peptide chromatography), proteomics increasingly finds its place ...
Data Processing
Data Processing

... Samples: 50µL serum precipitated with 150µL cold methanol, 0.1% formic acid Internal Standard: 5µg/mL of d5-Hippuric acid (200µL) Column: Hypersil GOLD aQ 2.1x150mm, 1.9µm, 50°C ...
chebi-and-plants - Buffalo Ontology Site
chebi-and-plants - Buffalo Ontology Site

... Not exactly a biological role Not a binary relationship ...


... hamster ovary (CHO) cells. CHO cells were grown in parallel cultures over a period of six days with glucose and glutamine feeding. On days 2 and 5, isotopic tracers were introduced and (13)C-labeling of intracellular metabolites was measured by gas chromatography-mass spectrometry (GC-MS). Metabolit ...
Standard Assays Offered by the Lipomics Laboratory. • Lipid
Standard Assays Offered by the Lipomics Laboratory. • Lipid

...  Oxidative stress markers. Oxidative stress plays a central role in several disorders including diabetes, obesity and cardiovascular disease. Dr. Pennathur’s laboratory has pioneered analytical strategies to quantitatively measure amino acid oxidation markers which serve as molecular fingerprints o ...
Health assessment of freshwater mussels using metabolomics
Health assessment of freshwater mussels using metabolomics

... Objective: Assess the metabolic changes in freshwater mussels brought into captivity and subjected to food limitation Hypothesis: Freshwater mussels held in captivity experience nutritional deficiency which will be exhibited by changes in metabolites associated with energy-producing pathways. ...
Plant Metabolic Eng
Plant Metabolic Eng

... 4. Recommended background knowledge: Basic knowledge about some secondary metabolites : terpens, fatty acids, alkaloids, flavonoids ...
Cheminformatics and metabolism resources
Cheminformatics and metabolism resources

... Mutation ...
Rakesh Singh - FSU Office of Research
Rakesh Singh - FSU Office of Research

... Name: ...
Supplemental Methods Statistical analysis. All NMR spectra were
Supplemental Methods Statistical analysis. All NMR spectra were

... Intermediates metabolites from β-oxidation, amino acid, NAD, SCFA, TCA and Urea metabolic pathways assigned in urine and stool 1H NMR spectra were relatively quantified by peak integration. The urinary and fecal excretions of these metabolites were further analysed using Wilcoxon-Mann-Whitney tests ...
jeremy-nicholson - New England Drug Metabolism Discussion
jeremy-nicholson - New England Drug Metabolism Discussion

... Institute, US; Heart Foundations of Canada, Great Britain, Japan and the Netherlands; Chicago Health Research Foundation; Parastatal Insurance, Company, Belgium; and by many national agencies supporting local studies. ...
Introduction to NMR Metabolomics
Introduction to NMR Metabolomics

... Calculated with a statistical package, like R ...
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Metabolomics

Metabolomics is the scientific study of chemical processes involving metabolites. Specifically, metabolomics is the ""systematic study of the unique chemical fingerprints that specific cellular processes leave behind"", the study of their small-molecule metabolite profiles. The metabolome represents the collection of all metabolites in a biological cell, tissue, organ or organism, which are the end products of cellular processes. mRNA gene expression data and proteomic analyses reveal the set of gene products being produced in the cell, data that represents one aspect of cellular function. Conversely, metabolic profiling can give an instantaneous snapshot of the physiology of that cell. One of the challenges of systems biology and functional genomics is to integrate proteomic, transcriptomic, and metabolomic information to provide a better understanding of cellular biology.
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