Wnt Signaling Translocates Lys48-Linked
... GSK3 sites showed that Wnt signaling, through the inhibition of GSK3, stabilizes many proteins in addition to b-catenin (Taelman et al., 2010; Kong et al., 2013; Acebron et al., 2014). Because Wnt signaling is highest at the G2/M phase of the cell cycle, the important proposal was made that the resu ...
... GSK3 sites showed that Wnt signaling, through the inhibition of GSK3, stabilizes many proteins in addition to b-catenin (Taelman et al., 2010; Kong et al., 2013; Acebron et al., 2014). Because Wnt signaling is highest at the G2/M phase of the cell cycle, the important proposal was made that the resu ...
Plasmablast and Plasma Cell Production and Distribution in Trout
... then blocked by the addition of the blocking solution for 1 h. Biotinylated mAb 1–14 (0.5 g/ml) was then added to the membrane and incubated at room temperature for 1 h on a rotary table, followed by a 1-h incubation with 30 ng/ml streptavidin-HRP (Sigma-Aldrich) in PBS. Forty milliliters of the su ...
... then blocked by the addition of the blocking solution for 1 h. Biotinylated mAb 1–14 (0.5 g/ml) was then added to the membrane and incubated at room temperature for 1 h on a rotary table, followed by a 1-h incubation with 30 ng/ml streptavidin-HRP (Sigma-Aldrich) in PBS. Forty milliliters of the su ...
G α 12/13 regulate epiboly by inhibiting E
... defect was observed in E-cadherin–deficient embryos, with cells bulging and detaching from the embryonic surface (Babb and Marrs, 2004; Kane et al., 2005; McFarland et al., 2005; Shimizu et al., 2005). E-cadherin is a plasma membrane glycoprotein that is indirectly linked to the actin cytoskeleton t ...
... defect was observed in E-cadherin–deficient embryos, with cells bulging and detaching from the embryonic surface (Babb and Marrs, 2004; Kane et al., 2005; McFarland et al., 2005; Shimizu et al., 2005). E-cadherin is a plasma membrane glycoprotein that is indirectly linked to the actin cytoskeleton t ...
Live cell imaging reveals actin-cytoskeleton
... We apologise to the authors and readers for any confusion that this error might have caused. ...
... We apologise to the authors and readers for any confusion that this error might have caused. ...
SP600125 Selectively Inhibits Histone H3
... or mutations in chromatin modifying enzymes and regulatory proteins. The phosphorylation of histone H3 at serine 10 (histone H3-Ser10) is conserved through eukaryotes, and an increase in phosphorylation has been shown to correlate with gene activation and cell growth (2). In contrast to many studies ...
... or mutations in chromatin modifying enzymes and regulatory proteins. The phosphorylation of histone H3 at serine 10 (histone H3-Ser10) is conserved through eukaryotes, and an increase in phosphorylation has been shown to correlate with gene activation and cell growth (2). In contrast to many studies ...
Meiosis - Faculty Bennington
... Meiosis functions to reduce the number of chromosomes to one half. Each daughter cell that is produced will have one half as many chromosomes as the parent cell. Meiosis is part of the sexual process because gametes (sperm, eggs) have one half the chromosomes as diploid (2N) individuals. In animals, ...
... Meiosis functions to reduce the number of chromosomes to one half. Each daughter cell that is produced will have one half as many chromosomes as the parent cell. Meiosis is part of the sexual process because gametes (sperm, eggs) have one half the chromosomes as diploid (2N) individuals. In animals, ...
Bacterial Inhibition
... between bacteria and humans. However, some antibiotics interfere with the function of human mitochondria which possess ribosomes similar to those found in bacteria. In addition, the antibiotics kill the normal bacterial flora that live in the human digestive tract. These normal bacteria are actually ...
... between bacteria and humans. However, some antibiotics interfere with the function of human mitochondria which possess ribosomes similar to those found in bacteria. In addition, the antibiotics kill the normal bacterial flora that live in the human digestive tract. These normal bacteria are actually ...
sites of protein synthesis in nucleoli of root meristematic cells of
... Structural organization of the interphase nucleolus Light microscopy. A. cepa is a diploid species with a single pair of nucleolar chromosomes (Heitz, 1931). Two nucleoli, therefore, are formed at telophase and these, during interphase, may remain distinct (Fig. 1) or adhere to form a dumbbell-shape ...
... Structural organization of the interphase nucleolus Light microscopy. A. cepa is a diploid species with a single pair of nucleolar chromosomes (Heitz, 1931). Two nucleoli, therefore, are formed at telophase and these, during interphase, may remain distinct (Fig. 1) or adhere to form a dumbbell-shape ...
Centromere dynamics
... be visualized upon introduction of Lac repressor fused to GFP [32]. Placement of the lacO array at varying distance from the centromere revealed that chromosome arms were closely apposed, whereas about 10 kb of pericentric chromatin is stretched pole-ward in mitosis, before anaphase onset [33–36]. S ...
... be visualized upon introduction of Lac repressor fused to GFP [32]. Placement of the lacO array at varying distance from the centromere revealed that chromosome arms were closely apposed, whereas about 10 kb of pericentric chromatin is stretched pole-ward in mitosis, before anaphase onset [33–36]. S ...
Specific localization of nesprin-1-α2, the short isoform of nesprin
... Background: Nesprin-1-giant (1008kD) is a protein of the outer nuclear membrane that links nuclei to the actin cytoskeleton via amino-terminal calponin homology domains. The short nesprin-1 isoform, nesprin-1-α2, is present only in skeletal and cardiac muscle and several pathogenic mutations occur w ...
... Background: Nesprin-1-giant (1008kD) is a protein of the outer nuclear membrane that links nuclei to the actin cytoskeleton via amino-terminal calponin homology domains. The short nesprin-1 isoform, nesprin-1-α2, is present only in skeletal and cardiac muscle and several pathogenic mutations occur w ...
Det här verket är upphovrättskyddat enligt Lagen (1960
... Hormone secretion. Since the hormones are bound to thyro globulin in peptide linkage (37), release of the hormones ne cessitates that the thyroglobulin is hydrolyzed. This degra dation is obviously not possible in the follicle lumen (43) but takes place in the follicle cells, which requires that ...
... Hormone secretion. Since the hormones are bound to thyro globulin in peptide linkage (37), release of the hormones ne cessitates that the thyroglobulin is hydrolyzed. This degra dation is obviously not possible in the follicle lumen (43) but takes place in the follicle cells, which requires that ...
Golgi clusters and vesicles mediate mitotic inheritance
... for a particular cell type and size, and they seed Golgi regrowth, we have argued that they are the partitioning units of the Golgi apparatus (Shima et al., 1997, 1998). An alternative view has recently been put forward by Lippincott-Schwartz and colleagues based on the hypothesis that the Golgi app ...
... for a particular cell type and size, and they seed Golgi regrowth, we have argued that they are the partitioning units of the Golgi apparatus (Shima et al., 1997, 1998). An alternative view has recently been put forward by Lippincott-Schwartz and colleagues based on the hypothesis that the Golgi app ...
On the mechanisms of nectar secretion: revisited
... photosynthate unloading and their further diffusion in the symplasm without entering the apoplasm. The situation in these systems appears to be similar to that occurring in nectaries devoid of their own phloem. Based on recent information regarding the cell ultrastructure and physiology of nectaries ...
... photosynthate unloading and their further diffusion in the symplasm without entering the apoplasm. The situation in these systems appears to be similar to that occurring in nectaries devoid of their own phloem. Based on recent information regarding the cell ultrastructure and physiology of nectaries ...
PHAGOLYSOSOME FORMATION IN NORMAL AND
... (approximately 85%) just below the interface between 10% sucrose and 5% sucrose . The remainder of the PVT was found at the 10-27.5% sucrose interface (Fig . 2). Since PVT centrifuged in discontinuous gradients without cell material being present also separated into two fractions, the two population ...
... (approximately 85%) just below the interface between 10% sucrose and 5% sucrose . The remainder of the PVT was found at the 10-27.5% sucrose interface (Fig . 2). Since PVT centrifuged in discontinuous gradients without cell material being present also separated into two fractions, the two population ...
F-actin Sequesters Elongation Factor from Interaction with
... been demonstrated to bind directly to actin filaments (Bektas et al., 1994). Colocalization of these components with the cytoskeleton supports the speculation that protein synthesis in vivo is channeled, i.e., the components are organized in a high degree of spatial order and intermediates are trans ...
... been demonstrated to bind directly to actin filaments (Bektas et al., 1994). Colocalization of these components with the cytoskeleton supports the speculation that protein synthesis in vivo is channeled, i.e., the components are organized in a high degree of spatial order and intermediates are trans ...
Localization of Phospholamban in Smooth Muscle
... smooth muscle cells is less than that observed in similar preparations of canine cardiac muscle (unpublished observations) and it often forms small patches. A striking feature of these cells is that the outer nuclear envelope is quite heavily labeled, indicating the presence of an abundant PL-like p ...
... smooth muscle cells is less than that observed in similar preparations of canine cardiac muscle (unpublished observations) and it often forms small patches. A striking feature of these cells is that the outer nuclear envelope is quite heavily labeled, indicating the presence of an abundant PL-like p ...
CONDUCTION INTRODUCTION
... Conduction of an action potential in myelinated fibers occurs by a process known as saltatory conduction. By this we mean that the action potential is conducted with great speed between nodes (due to greatly decreased time constant for conduction) and pauses to regenerate itself only at the nodes of ...
... Conduction of an action potential in myelinated fibers occurs by a process known as saltatory conduction. By this we mean that the action potential is conducted with great speed between nodes (due to greatly decreased time constant for conduction) and pauses to regenerate itself only at the nodes of ...
An Ultrastructural Study of the Gastric Campylobacter
... mucus that normally lines the stomach. We have been unable to isolate the organism from samples of mucus taken from the small and large bowel at colonoscopy (D. M. Jones & J. Eldridge, unpublished observations). It is probably a commensal although clearly it has some association with gastritis. It h ...
... mucus that normally lines the stomach. We have been unable to isolate the organism from samples of mucus taken from the small and large bowel at colonoscopy (D. M. Jones & J. Eldridge, unpublished observations). It is probably a commensal although clearly it has some association with gastritis. It h ...
Resistance Gene-Dependent Activation of a Calcium
... The plant defense is triggered by a signaling network of parallel pathways that may be interlinked at single components. The increase in the cytosolic Ca2⫹ concentration, which occurs within seconds after elicitation, appears to be a master regulator required for many subsequent signaling steps. AOS ...
... The plant defense is triggered by a signaling network of parallel pathways that may be interlinked at single components. The increase in the cytosolic Ca2⫹ concentration, which occurs within seconds after elicitation, appears to be a master regulator required for many subsequent signaling steps. AOS ...
Slide PDF - The future of science
... • Transporters of lysosomal proteins residing at the TGN (M6PRs) • Proteins involved in lysosomal acidification (proton pump subunits) • Proteins involved in autophagy (UVRAG, VPSs) ...
... • Transporters of lysosomal proteins residing at the TGN (M6PRs) • Proteins involved in lysosomal acidification (proton pump subunits) • Proteins involved in autophagy (UVRAG, VPSs) ...
Formation of the leading edge boundary
... Understanding how LE cells become distinct from other dorsal ectodermal cells may provide additional clues to explain the restriction of JNK pathway activity. Perhaps the LE is intrinsically different from the remainder of the dorsal ectoderm at an early stage in embryogenesis, making LE cells uniqu ...
... Understanding how LE cells become distinct from other dorsal ectodermal cells may provide additional clues to explain the restriction of JNK pathway activity. Perhaps the LE is intrinsically different from the remainder of the dorsal ectoderm at an early stage in embryogenesis, making LE cells uniqu ...
1 - UvA-DARE - University of Amsterdam
... construct and showed that the exon 7+ polyA sequence is essential for the formation of the alternative splice form GFAPδ. Whether GFAPδ is expressed, is partly regulated by the splice regulators of the family of serine rich (SR) proteins. It has been shown that high expression of the SR protein poly ...
... construct and showed that the exon 7+ polyA sequence is essential for the formation of the alternative splice form GFAPδ. Whether GFAPδ is expressed, is partly regulated by the splice regulators of the family of serine rich (SR) proteins. It has been shown that high expression of the SR protein poly ...
Intelligent Monitoring System Satisfies Customer Needs for
... the string. The monitor will alarm when there is a sufficient imbalance in the half-string voltage caused by one or more blocks (or cells) that have deviated from the pack on voltage. Mid point monitoring has significant limitations. As the system voltage increases, mid-point voltage monitoring lose ...
... the string. The monitor will alarm when there is a sufficient imbalance in the half-string voltage caused by one or more blocks (or cells) that have deviated from the pack on voltage. Mid point monitoring has significant limitations. As the system voltage increases, mid-point voltage monitoring lose ...
The Mechanisms and Mechanics of Archenteron Elongation during
... The first result of the mechanical simulations is that when such shapes are modeled as elastic structures solely under the influence of filopodial pulling, the correct morphology cannot be obtained (Figs. Za, c). When the archenteron possesses the same mechanical properties as the rest of the embryo ...
... The first result of the mechanical simulations is that when such shapes are modeled as elastic structures solely under the influence of filopodial pulling, the correct morphology cannot be obtained (Figs. Za, c). When the archenteron possesses the same mechanical properties as the rest of the embryo ...
Cytokinesis
Cytokinesis (cyto- + kinesis) is the process during cell division in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the early stages of mitosis, and sometimes meiosis, splitting a mitotic cell in two, to ensure that chromosome number is maintained from one generation to the next. After cytokinesis two (daughter) cells will be formed that are exact copies of the (parent) original cell. After cytokinesis, each daughter cell is in the interphase portion of the cell cycle. In animal cells, one notable exception to the normal process of cytokinesis is oogenesis (the creation of an ovum in the ovarian follicle of the ovary), where the ovum takes almost all the cytoplasm and organelles, leaving very little for the resulting polar bodies, which then die. Another form of mitosis without cytokinesis occurs in the liver, yielding multinucleate cells. In plant cells, a dividing structure known as the cell plate forms within the centre of the cytoplasm and a new cell wall forms between the two daughter cells.Cytokinesis is distinguished from the prokaryotic process of binary fission.