• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Hardy-Weinberg Principle
Hardy-Weinberg Principle

... In order to apply the Hardy-Weinberg Equilibrium/Population Equilibrium the following conditions are required: – Large populations – Random mating – No mutation – No migration – Equal viability, fertility, and mating ability of all genotypes ...
ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS
ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS

... consequence of disturbance of the microcirculation, prescription of a diuretic is not helpful. The combined pre-capillary and post-capillary action of lercanidipine may reduce the frequency of this side effect. Peripheral oedema may also be reduced by co-administration of an ACE inhibitor or angiote ...
Linkage Disequilibrium
Linkage Disequilibrium

...  Most successful AM experiments have uncovered loci previously known to affect a trait  Other experiments with traits not evaluated extensively before have just defined associated regions o Causative genes have not been defined ...
Pharmacological
Pharmacological

... The study of how [and to what degree] genetic polymorphism (genetic diversity) impacts drug responsiveness o Idiosyncratic responses  Pharmacokinetic – drug metabolism  Pharmacodynamics – drug target sites o Drug response varies inside a population (shows a Gaussian distribution) Drug metabolism c ...
The use of oral hypoglycemic agents
The use of oral hypoglycemic agents

... drug interactions; and long-term benefits from longterm adherence rather than just short-term symptom relief – if there are any symptoms. In any case, a shared agenda between patient and professional is vital for successful treatment and monitoring of effects, both in the short term and long term. ...
Bez nadpisu - Univerzita Karlova v Praze
Bez nadpisu - Univerzita Karlova v Praze

...  type of C1 INH mutation associated rather with laboratory phenotype than clinical manifestation • missense mutation in the reactive center loop - 75% patients with HAE type II • large deletions, nonsense, frameshift and splicing mutations – causal usually in HAE type I • inframe del/ins, missense ...
Addressing unique medication adherence issues for
Addressing unique medication adherence issues for

... medications greatly contribute to a culherent patient include: comorbid subtheir illness and cognitive deficits that ture of nonadherence not only in schizostance abuse, poorer cognitive function- phrenia but also in many behavioral can interfere with treatment adherence. ing, reduced quality of lif ...
Variation, probability, and pedigree
Variation, probability, and pedigree

Study title: A series of N-of-1 trials to assess therapeutic
Study title: A series of N-of-1 trials to assess therapeutic

... The burden of major non-communicable diseases in Ethiopia is increasing. In 2011, the World Health Organization (WHO) estimated that 34% of the Ethiopian population will die from noncommunicable diseases, with a national cardiovascular disease prevalence of 15%, cancer and chronic obstructive pulmon ...
GENETIC TRAITS
GENETIC TRAITS

... observed if the second copy is also recessive, or being hidden if the second copy is dominant. • Trait: A genetically determined characteristic CLASS: Discussion (~ 5 minutes) • What is a trait? Anything that identifies as both unique (e.g. hair color, eye color, height) and human (e.g. face, one he ...
Dirithromycin (Dynabac): same as erythromycin base but once daily
Dirithromycin (Dynabac): same as erythromycin base but once daily

... - more complete absorption - longer duration of activity - TID administration ...
outline29476
outline29476

... apparent by the number of people affected by a particular disorder. 3. Genes, environment, and behaviors interact with each other to cause disease. A family history helps capture the effects of all 3 of these interactions on disease risk. 4. Benefits of taking a genetic family history B. Collection ...
PATTERNS OF INHERITANCE
PATTERNS OF INHERITANCE

... a. one gene affects many characteristics _______________________ b. allele that is located on an X chromosome _______________________ c. having a dominant and recessive allele for a trait _______________________ d. several alleles located on same chromosome; inherited together ______________________ ...
Classroom Expectations
Classroom Expectations

... To demonstrate the effect of different types of CNS depressants as : - General anaesthetics - Hypnotics ‫المنومات‬ - Sedatives ‫المسكنات‬ - tranquilizers ‫المهدئات‬ To learn how to distinguish between their signs if they are given as unknown drugs. ...
OpioidAnalgesics_2
OpioidAnalgesics_2

... • Morphine has many side effects. The most dangerous is respiratory depression. With higher doses or in frail patients, the respiratory rate decreases, the patient becomes increasingly sedated, and the pupils very small. • Common side effects are nausea and vomiting due to a central action of morphi ...
chapter 14
chapter 14

... terms. 21. Describe how environmental conditions can influence the phenotypic expression of a character. Explain what is meant by “a norm of reaction.” 22. Distinguish between the specific and broad interpretations of the terms phenotype and genotype. Mendelian Inheritance in Humans Explain why stud ...
Student Handout
Student Handout

... of Dipyridamole. These two drugs do not interact, so the pharmacokinetics in combination are the same as when each is administered in isolation. I presently weigh 188 pounds and have approximately 60 milliliters of blood per kilogram body weight a) Use the pharmacokinetic information below to develo ...
Assessment Schedule 2010 AS 90459 (Biology 2.3) Describe
Assessment Schedule 2010 AS 90459 (Biology 2.3) Describe

... processes linked to the decrease of diversity in the gene pool and the rapid increase in frequency of favourable alleles in the gene pool of the robins on Ulva island. ...
File
File

...  The hereditary determinants maintain their integrity from generation to generation 3. Each gamete contains one allele of each gene  Law of segregation 4. Males and females contribute equally to the genotype of the offspring  When gametes fuse together the offspring has one allele from each paren ...
The Vermont Legislative Research Shop Methadone
The Vermont Legislative Research Shop Methadone

... What is the relationship between heroin use, HIV, and methadone therapy? The relationship between heroin use through needle injection and contraction of the HIV virus is important to consider. Because patients are receiving controlled methadone treatment the risk of users being infected by HIV thro ...
Mendelian Genetics Problems
Mendelian Genetics Problems

... a) How are these fur traits inherited? b) Indicate the genotypes of each phenotype using appropriate symbols. Be sure to indicate the meaning of the symbols. 4. Diabetes has been found to be inherited (in many cases) through a recessive allele “d.” How can two nondiabetic parents have a diabetic chi ...
Club drugs: review of the `rave` - Indian Council of Medical Research
Club drugs: review of the `rave` - Indian Council of Medical Research

... alcohol or other CNS depressants55. GHB was first synthesized in France in 1960 as an anesthetic but later achieved popularity as a recreational drug and a nutritional supplement marketed to bodybuilders56. Nonprescription sales in the United States were banned in 1990 because of adverse effects, ...
The Role Of Vitamin Therapy In Drug Rehabilitation
The Role Of Vitamin Therapy In Drug Rehabilitation

... treatment are doing so for the third time, are using multiple substances, and have other health and social problems.2 Continuously high failure rates have caused some experts to conclude that addiction is an incurable disease. However, it is also possible that treatment models in current use are ina ...
Slide 1
Slide 1

... – FDA: the highest dose strength is soluble in 250 mL or less of aqueous media over a pH range of 1 to 7.5, at 37°C ± 1°C – EMA: the highest single dose administered is soluble in 250 mL or less of buffer solutions of pH 1 to 6.8, at 37°C ± 1°C – WHO: the highest dose* is soluble in 250 mL or less o ...
slides - UBC Botany
slides - UBC Botany

... • What are the causes and evolutionary consequences of non-random mating? • What is genetic drift and what are its evolutionary consequences? • How do we determine if these mechanisms are acting in a population? ...
< 1 ... 694 695 696 697 698 699 700 701 702 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report