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Antiamoebic Drugs
Antiamoebic Drugs

... 2- They’re preferably given subcutaneously, but it could be given intramuscularly. 3- THEY COULD NEVER EVER BE GIVEN INTRAVENOUSLY. 4- They have a plasma half-life of 5 days. 5- Emetine is concentrated in the liver, lungs, spleen, kidneys, cardiac muscles, and intestinal walls. 6- Emetine is metabol ...
Slides
Slides

... nausea, contraindicated if Cr Cl < 50 ml/min • Efficacy: A phase III study showed improved walking (25 ft) in 43% pts vs 9% placebo ...
Healing Is In The Headxe
Healing Is In The Headxe

... patient's beliefs and expectations seem to have a significant biochemical effect or you can say it may invoke a "conditioned response" as studied by Ivan Pavlov. We are conditioned to believe that medicine makes us better when we're ill, so any treatment that we receive may make us psychologically c ...
Document
Document

... • Alleles at a single locus may have effects on two or more traits • Classic example is the effects of the mutant allele at the beta-globin locus that gives rise to sickle-cell anemia ...
A Highly Efficacious Risedronate
A Highly Efficacious Risedronate

... are available in Indonesia. The novel BISP, Risedronate (RIS) is 5-fold more potent than ALE. Most recent studies on PMO demonstrated that RIS of 35 mg, or 50 mg Once a Week (OaW) provided the same efficacy and safety as the daily 5 mg regimen; therefore, the lower dose, 35 mg OaW can be considered ...
1896grading1848 - DB
1896grading1848 - DB

Jeopardy - lumen.luc.edu
Jeopardy - lumen.luc.edu

... This atypical has a significant risk of causing hyperprolactinemia, is the active metabolite of risperidone (Risperdal), and needs to be taken with food ...
AA - Bryn Mawr School Faculty Web Pages
AA - Bryn Mawr School Faculty Web Pages

... Species A biological species is: a grouping of organisms that can interbreed and are reproductively isolated from other such groups. Species are recognized on the basis of their morphology (size, shape, and appearance) and, more recently, by genetic analysis. For example, there are up to 20 000 spec ...
An Introduction to Drug Disposition: The Basic Principles of
An Introduction to Drug Disposition: The Basic Principles of

... Substrates for CYP2D enzymes possess a basic nitrogen grouping that is mainly ionized at physiological pH, a hydrophobic region and a functional group capable of P-450 oxidation 5-7 A from the basic nitrogen (69). Reactions catalyzed include aromatic hydroxylation (propranolol), aliphatic hydroxylat ...
Medical Assistant Pharmacology - Career and Technical Education
Medical Assistant Pharmacology - Career and Technical Education

...  hypoglycemic  laxative  muscle relaxant  sedative  vasodilator  vasopressor Review factors that affect drug action such as absorption, distribution, biotransformation, and elimination. therapeutic action and side effects of specific drugs Possible assignment activity: conduct an online search ...
Treatment of amebiasis
Treatment of amebiasis

... abscesses at the injection site. 2- GIT disturbances and diarrhea. 3- Muscle weakness and discomfort. 4- Serious toxicities: cardiac arrhythmias, heart failure, and hypotension. ...
Herbal Medicines in the Treatment of Depression and Anxiety , )
Herbal Medicines in the Treatment of Depression and Anxiety , )

... have weaker clinical effects than whole plant extract, a claim that would obviously require proof in each case. Although a multitude of pharmaceutical agents are available for the treatment of mental disorders, physicians find that many patients cannot tolerate the side effects, do not respond adequ ...
Document
Document

... • Adjust for renal, hepatic, and age-related factors. • 75% renal elimination • Extensive liver metabolism • T ½ - 135 mins ...
Institutional Diversion Prevention, Detection and Response
Institutional Diversion Prevention, Detection and Response

... Removing Dilaudid doses when there isn t an order (in anticipation of getting one) Wasting entire syringes of Dilaudid but returning other CS not used Dividing one time Dilaudid doses so that more than one syringe can be obtained Failing to waste Dilaudid Requesting orders for Dilaudid when other me ...
Allele
Allele

... Alleles for the trait are located on the X chromosome in humans. - works the same in women as all the other traits. ...
Can drug resistance in epilepsy be minimized?
Can drug resistance in epilepsy be minimized?

... serum drug concentrations, a procedure known as “therapeutic drug monitoring (TDM)” (Eadie 1998). Therapeutic failure can result from prescription of insufficient dosages, but there are also cases where apparent drug resistance results from prescription of excessive dosages leading to adverse effect ...
Anna Jokiel Raskin - Cardiac Mechanics Research Group
Anna Jokiel Raskin - Cardiac Mechanics Research Group

... GPA 4.0 Designed (Auto-CAD), developed, optimized, and validated mouse cardiac tissue culture chamber (6-12 hour culture) that facilitates uni-axial straining while simultaneously measuring muscle force and strain. System is capable of inducing hypertrophy at the level of molecular biology in intact ...
Harvey M. Richey DO, FCCP Interim Regional Chairman Department of Medicine
Harvey M. Richey DO, FCCP Interim Regional Chairman Department of Medicine

... * Definitions of ratings: A: preferred; B: acceptable alternative; C: offer when A and B cannot be given; E: should never be given. When DOT is used, drugs may be given 5 days/week and the necessary number of doses adjusted accordingly. Although there are no studies that compare five with seven dail ...
Article: Prevent Med Errors
Article: Prevent Med Errors

... Food and Drug Administration (FDA) required that all newly approved drugs be packaged with a linear bar code, containing the National Drug Code number, within 60 days of approval. Despite the FDA mandate, the implementation of bar coding technology within healthcare systems has been slow. Inpatient ...
GENETICS PROBLEMS A man with a widow`s peak (WW) marries a
GENETICS PROBLEMS A man with a widow`s peak (WW) marries a

... 9. The fruit pods of peas can be yellow or green. In one of his experiments, Mendel crossed plants that were homozygous for the allele for yellow fruit pods with plants that were homozygous for the allele for green fruit pods. All fruit pods in the F1 generation were green. Which allele is dominant, ...
4-Antimanic (edited)..
4-Antimanic (edited)..

... are thus commonly prescribed even when psychotic symptoms are absent • They affect glucose and lipid levels and cause weight gain. ...
Choosing the Right Over-the-Counter Treatment for You and Your
Choosing the Right Over-the-Counter Treatment for You and Your

... with your pharmacist or physician about the medication, including its purpose, benefits, side effects, and any possible drug interactions. Your pharmacist can help you select the right OTC medications for you and your loved ones. Ask your pharmacist these six questions before taking any new OTC medi ...
ZYMAXID® Prescribing Information
ZYMAXID® Prescribing Information

... was found in the breast milk of rats following oral administration of gatifloxacin during lactation. However, systemic levels of gatifloxacin following topical ocular administration are low [see Clinical Pharmacology (12.3)], and it is not known whether gatifloxacin would be present in maternal milk ...
Specifications Breakout
Specifications Breakout

... – Good to show what companies are considering and monitoring, but if it adds no value to the critical evaluation of the ED study (i.e. unrelated to safety), is it useful to include? Some companies continue to monitor but not include in filing. – Sometimes additional testing is determined not to prov ...
Clinical Guidelines on the Identification, Evaluation, and Treatment
Clinical Guidelines on the Identification, Evaluation, and Treatment

... LDL-Lowering Therapy in Patients With CHD and CHD Risk Equivalents Baseline (or On-Treatment) LDL-C: 100–129 mg/dL Therapeutic Options: • LDL-lowering therapy – Initiate or intensify lifestyle therapies – Initiate or intensify LDL-lowering drugs • Treatment of metabolic syndrome – Emphasize weight r ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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