• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Review of the Available Evidence on “Newer”
Review of the Available Evidence on “Newer”

... respectively. Therefore, the availability of an AED showing to be effective in both types of seizures and on pediatric as well as adult patients would be a useful treatment option in clinical practice, since it could be offered to the majority of persons with epilepsy. Assessing the place in therapy ...
Strategies for Identifying and Avoiding Hypoglycemia in Your Type 2
Strategies for Identifying and Avoiding Hypoglycemia in Your Type 2

... to compensate by avoiding hypoglycemia at all costs and deliberately maintain a degree of hyperglycemia, having an adverse effect on their glycemic control. Hypoglycemia Can Have Serious Consequences for Patients’ Health Normal brain function requires an adequate, continuous supply of glucose in the ...
Presentazione di PowerPoint
Presentazione di PowerPoint

... “Inheritance of one trait is determined by pairs of ‘factors’ that segregate in the gamete formation” Each gamete contains only one factor from each pair ...
A review of the evidence for carbamazepine and oxcarbazepine in
A review of the evidence for carbamazepine and oxcarbazepine in

... and the prevention of future episodes. Mood stabilizers are currently the basis of most treatment regimens. Lithium is the classical mood stabilizer (its action was first noted by Cade in 1949), and there is good evidence suggesting that it prevents relapse and recurrence long term. In addition, pati ...
Vol 6 No 4
Vol 6 No 4

... pH and Buffering-Ophthalmic solutions are ordinarily buffered at the pH of maximum stability for the drug(s) they contain. The buffers are included to minimize any change in pH during the storage life of the drug; this can result from absorbed CO2 from the air or from hydroxyl ions from a glass cont ...
Effects of phenytoin and carbamazepine on calcium transport in
Effects of phenytoin and carbamazepine on calcium transport in

... terminal telopeptide I of type I collagen) levels are positively correlated with anti-epileptic drug therapy (Valimaki et al., 1994; Verrotti et al., 2000). Plausible mechanisms for antiepileptic drug-induced hypocalcemia include induction of vitamin D catabolism, inhibition of parathyroid hormonein ...
Systems biology of inborn errors of metabolism
Systems biology of inborn errors of metabolism

... Inborn errors of metabolism (IEMs) are the hereditary metabolic disorders often leading to life threatening conditions when left un-treated. IEMs not only demand better diagnostic methods and efficient therapeutic regimen, but also, a high level understanding of the precise biochemical pathology inv ...
EXFORGE 5/80 EXFORGE 5/160 EXFORGE 10/160
EXFORGE 5/80 EXFORGE 5/160 EXFORGE 10/160

... complete the core studies with well controlled blood pressure and no serious drug-related adverse experiences. The results demonstrated that amlodipine/valsartan 160/5, 160/10 and 5/320 mg are effective in providing long-term blood pressure. In patients whose blood pressure is adequately controlled ...
High-Throughput Screening - Journal of Applied Pharmaceutical
High-Throughput Screening - Journal of Applied Pharmaceutical

... steps like fluid addition, incubation and reading. Homogeneous assays are simpler consisting of the latter three usual steps, this may also be called true homogeneous assay. However at times homogeneous assays could be complex due to the need for multiple addition and different incubation times. Tho ...
SEROQUEL (quetiapine fumarate) TABLETS HIGHLIGHTS OF PRESCRIBING INFORMATION
SEROQUEL (quetiapine fumarate) TABLETS HIGHLIGHTS OF PRESCRIBING INFORMATION

... SEROQUEL dose should be increased up to 5 fold of the original dose when used in combination with a chronic treatment (e.g., greater than 7-14 days) of a potent CYP3A4 inducer (e.g., phenytoin, carbamazepine, rifampin, avasimibe, St. John’s wort etc.). The dose should be titrated based on the clinic ...
IN THE NAME OF GOD FAKHRADDIN FAIZI
IN THE NAME OF GOD FAKHRADDIN FAIZI

... be available as a specific antidote; basic life support measures may be necessary. ...
Seroquel - PI
Seroquel - PI

... SEROQUEL dose should be increased up to 5 fold of the original dose when used in combination with a chronic treatment (e.g., greater than 7-14 days) of a potent CYP3A4 inducer (e.g., phenytoin, carbamazepine, rifampin, avasimibe, St. John’s wort etc.). The dose should be titrated based on the clinic ...
The Effectiveness of Digoxin in Treating Heart Failure
The Effectiveness of Digoxin in Treating Heart Failure

... (CHF) and half of those diagnosed will die within five (5) years. In addition, there is an exorbitant cost associated with heart failure, an estimated $30.7 billion yearly [1]. Katzung, states that positive inotropic drugs are effective for acute heart failure, however, other research have shown tha ...
NIDA for Teens Ecstasy Quiz
NIDA for Teens Ecstasy Quiz

English - Illumina
English - Illumina

... Gardner RJM, Sutherland GR, Schaffer LG. Chromosome Abnormalities and Genetic Counseling. 4th ed. New York, NY: Oxford University Press; 2012. ...
CP31 V01 Lyn Williams (Pharmacy)
CP31 V01 Lyn Williams (Pharmacy)

... This policy is the Trust approved document for managing the risks from extravasation which are associated with the administration of certain intravenous treatments including chemotherapy. It sets down general principles for dealing with an extravasation as well as drug-specific measures. 2.2 Equalit ...
6 Topiramate for the Management of Seizures in Children
6 Topiramate for the Management of Seizures in Children

Using Genetic Algorithms with Asexual Transposition
Using Genetic Algorithms with Asexual Transposition

... yet completely understood). She proved that certain phenomena present in living beings exposed to UV ...
MRI INTERVENTIONS, INC.
MRI INTERVENTIONS, INC.

... Forward Looking Statements Certain statements in this presentation may constitute forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements often can be identified by words such as “a ...
TASTE MASKING TECHNOLOGIES: A REVIEW  Review Article SHALINI SHARMA AND SHAILA LEWIS* 
TASTE MASKING TECHNOLOGIES: A REVIEW  Review Article SHALINI SHARMA AND SHAILA LEWIS* 

... bitternes of  quinine than  to sweetness  of sugar. Saccharine, on this  scale would rate about 0.001%.   Pharmaceutical  companies  can  save  themselves  much  grief  by  addressing  the  taste  factor  early  in  the  product  deelopment.  In  so  doing, they can get their medications to market m ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... studies.1to9 It is observed that subjects on olanzapine showed no increase in prolactin level, this observation is in agreement with the study by Kim KS et al where Switch over from risperidone to olanzapine showed normalisation of elevated prolactin and reversal of its adverse effects5 and their st ...
Slide Set
Slide Set

... terfenadine, astemizole, cisapride Caution is advised when EMEND is administered with the following chemotherapeutic agents: etoposide, vinorelbine, docetaxel, and paclitaxel ...
Marijuana
Marijuana

... In 1988 Judge Francis Young was quoted as saying : "In strict medical terms marijuana is far safer than many foods we commonly consume. For example, eating 10 raw potatoes can result in a toxic response. By comparison, it is physically impossible to eat enough marijuana to induce death. Marijuana i ...
“Synthesis, characterization and biomedical applications of microbial polymalic and polyglutamic acids derivatives.”
“Synthesis, characterization and biomedical applications of microbial polymalic and polyglutamic acids derivatives.”

... 20.2, 46.5, and 75.1, which are pretty close to the nominal values. Yields were higher than 90% for all the cases. The molecular weights of these copolyesters were practically coincident to the molecular weight of the parent polyacid indicating that very light degradation took place upon esterificat ...
Print - Arteriosclerosis, Thrombosis, and Vascular Biology
Print - Arteriosclerosis, Thrombosis, and Vascular Biology

... LDL derives from a defect in its synthesis from precursor VLDL. However, the present investigation and earlier data from Sigurdsson et al.7 do not support this view, but show that apo LDL production rates are normal. Rather, hypercatabolism is responsible for the effect. In theory, either the recept ...
< 1 ... 58 59 60 61 62 63 64 65 66 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report