• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Table – 7 shows comparison of time taken and total antihypertensive doses required to control BP between two groups, i.e. to achieve BP 150/90mm of Hg. The mean time required were 47.2 ± 13.5 mins in the Labetalol groups and 45.6 ± 14.5 minutes in the Nifedipine group. This comparison showed no diff ...
Update on the Management of Onychomycosis: Highlights of the
Update on the Management of Onychomycosis: Highlights of the

... to onychomycosis. The condition usually starts when trauma weakens the seal between the nail plate and the nail bed, allowing fungal organisms to penetrate the nail unit. The increased incidence of onychomycosis, which is associated with aging, may be due to slower growth of the nail, increased trau ...
prevpac - Takeda
prevpac - Takeda

... lansoprazole is given 30 minutes after food, compared to the fasting condition. There is no significant food effect if lansoprazole is given before meals. Distribution: Lansoprazole is 97% bound to plasma proteins. Plasma protein binding is constant over the concentration range of 0.05 to 5.0 mcg/mL ...
Consumption of antibacterial agents
Consumption of antibacterial agents

... daily dose (DDD). The DDD for an active pharmaceutical substance is the average maintenance dose used for its major indication in adults (9). All units except the proportion of prescription with antibacterial agents are normally adjusted for the population under risk over a given time period, usuall ...
JRRD Efficacy of gabapentin in treating chronic phantom limb and residual
JRRD Efficacy of gabapentin in treating chronic phantom limb and residual

... patients who received an 8-week trial of gabapentin (up to 3,600 mg/day) than in patients who received 8 weeks of placebo [16]. Quality of life (as measured by the 36-Item Short-Form Health Survey) and sleep were also significantly improved in the gabapentin-treated group compared with the placebo g ...
PRODUCT INFORMATION ViruPOS OPHTHALMIC OINTMENT
PRODUCT INFORMATION ViruPOS OPHTHALMIC OINTMENT

... The use of ViruPOS Ophthalmic Ointment should be considered only when the potential benefits outweigh the possibility of unknown risks. Systemic administration of aciclovir in internationally accepted standard tests did not produce embryotoxic or teratogenic effects in rabbits, rats or mice. Animal ...
UPDATE OF CANNABIS BACKGROUND PAPER
UPDATE OF CANNABIS BACKGROUND PAPER

... explanations which have been put forward by observers are discriminatory behaviour by law enforcement personnel, and/or people in low socio-economic groups having more incentive to engage in lucrative illegal activity. Official data demonstrates that Mäori are more likely to have lower incomes, high ...
this paper
this paper

... chronic administration of antidepressant drugs. Recently, the cAMP signaling pathway has been implicated in antidepressant action after chronic treatment. Increases in cAMP, via receptor adenylate cyclase activity, increase phosphorylation of the cAMP response element-binding protein (CREB). By bind ...
Frequently Asked Questions
Frequently Asked Questions

... What if the person is not even overdosing and I give them Naloxone? Will it hurt them? Naloxone has no effect on someone who has no opioids in their system. It will not help anyone who is not in an OD, but it will not hurt them either. Can someone overdose on Naloxone or what if I give too much Nalo ...
Presentations Indications Dosage and Administration
Presentations Indications Dosage and Administration

... Cranial lesions and high intracranial pressure. The respiratory depressant effects of methadone and its capacity to increase the cerebrospinal fluid pressure can be considerably increased in the presence of an increase of the intracranial pressure; furthermore narcotics produce undesirable effects, ...
Hypericum perforatum Monograph
Hypericum perforatum Monograph

... pregnancy or lactation,78 this statement appears to be based more on historical use than actual safety studies. One prospective study of 33 breast-feeding women and disease- and age-matched controls demonstrated taking St. John’s wort did not affect milk production or infant weight or growth.79 ...
November 2015 PBAC Meeting Agenda
November 2015 PBAC Meeting Agenda

... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and re-submissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be lis ...
core modules & forms of tobacco
core modules & forms of tobacco

... Conditioned stimuli Social interactions ...
Polyethylene Glycol 3350 (PEG 3350) Frequently Asked
Polyethylene Glycol 3350 (PEG 3350) Frequently Asked

... Generally speaking, if your child has been prescribed PEG 3350 as part of his/her treatment plan, and you feel this medicine provides benefit, you should feel safe continuing PEG 3350. At this time, PEG 3350 appears to be safe based on current medical literature. We recommend discussing any concerns ...
Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent
Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent

... experience anxiety or dissociative symptoms [67] or improved sleep quality, as assessed by standardized rating scales. We did not include in this review studies on cannabis extracts or CBD-rich extracts, as the other several compounds may have multiple interactions with CBD. However, some clinical t ...
Genomic variations and distinct evolutionary rate of rare alleles in
Genomic variations and distinct evolutionary rate of rare alleles in

... diminish from the population and takes many generations to give rise to a reasonable allelic frequency. Whereas, a common allele may be recent which emerge from a rapid population expansion [5]. Rare variants seem to have dominant effects containing haplotypes with functional alleles [9]. They relat ...
S02 Techno2 Hard Gelatin Capsules
S02 Techno2 Hard Gelatin Capsules

... D: Lubricants: reduce powder to metal adhesion, such as magnesium stearate. They exert their effect by coating the surface of other ingredients. Lubricants are usually hydrophobic materials that achieve their activity by coating the surface of pharmaceutical powders. At high levels they can reduce t ...
Nicotine Pharmacology and Principles of
Nicotine Pharmacology and Principles of

... Conditioned stimuli Social interactions ...
Cardizem LA
Cardizem LA

... and triazolam also increased (1.5- to 2.5-fold) during coadministration with diltiazem. These pharmacokinetic effects seen during diltiazem coadministration can result in increased clinical effects (e.g., prolonged sedation) of both midazolam and triazolam. Beta-blockers. Controlled and uncontrolled ...
The Health Consequences of Smoking - Rx for Change
The Health Consequences of Smoking - Rx for Change

... *Currently regulated by the FDA Center for Drug Evaluation and Research. It is anticipated that the FDA Center for Tobacco Control Products will regulate other nicotine-containing products , including electronic cigarette products that do not make a therapeutic claim, in the future. ...
Misoprostol in obstetrics and gynecology
Misoprostol in obstetrics and gynecology

... is given in Table 1. Some concepts are repeated in all articles, such as contraindications for the use of misoprostol. This is done so that each article can be consulted independently from the others. The exception is drug pharmacology, which called for a whole separate chapter. For the sake of brev ...
LC-Tandem MS Detection of Covalent Binding of Acetaminophen to
LC-Tandem MS Detection of Covalent Binding of Acetaminophen to

... DMD Fast Forward. Published on May 17, 2007 as DOI: 10.1124/dmd.106.014233 This article has not been copyedited and formatted. The final version may differ from this version. ...
Genotype C of hepatitis B virus can be classified into at least two
Genotype C of hepatitis B virus can be classified into at least two

... virulence and pathogenicity differ in each location (Lok, 2000; Kidd-Ljunggren et al., 2002). In addition, subgroups of HBV genotype have also been reported in genotypes A (A9 and A-A9) (Bowyer et al., 1997; Kramvis et al., 2002) and B (Ba and Bj) (Sugauchi et al., 2002a). The genotyping of HBV is i ...
I2326E-IF2326E- Savage NITROBID
I2326E-IF2326E- Savage NITROBID

... Dosing regimens for most chronically used drugs are designed to provide plasma concentrations that are continuously greater than a minimally effective concentration. This strategy is inappropriate for organic nitrates. Several well-controlled clinical trials have used exercise testing to assess the ...
Suprax (cefixime)
Suprax (cefixime)

... A false-positive reaction for ketones in the urine may occur with tests using nitroprusside but not with those using nitroferricyanide. The administration of beta-lactams may result in a false-positive reaction for glucose in the urine using Clinitest *, Benedict's solution, or Fehling's solution. I ...
< 1 ... 54 55 56 57 58 59 60 61 62 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report