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Read More - Klerksdorp Tshepong Hospital Complex
Read More - Klerksdorp Tshepong Hospital Complex

... bacteria without knowing they're are highly infectious as it was the case in the past. The GeneXpert is also a lot less resource intensive and as tests can be done locally. Also, sputum samples don't have to be sent for laboratory testing somewhere else. There is positive trails research in TB resea ...
Newsletters, ADR, MEDWATCH
Newsletters, ADR, MEDWATCH

... ADR or med error each year. • 4th to 6th leading cause of death each year ...
medication administration
medication administration

... It is the Poisons and Therapeutic Goods Act 1966 ( NSW ) who impose some limitation on the use of many potent drugs by restricting their distribution to certain groups or persons trained in handling them and permitting their administration only on medical authority. ...
Designer and look
Designer and look

... dealers began manufacturing it in illegal laboratories and selling it under the street name ecstasy.  The drug gained popularity in the late 1980s with the rise of raves—crowded, all-night dance parties usually held in secret locations such as warehouses.  As rave culture spread through Europe, th ...
ZkeQu&yChitt@enPeop& :7609 ?% MN21 4933 ALLEN’S HATCHERY, INC.
ZkeQu&yChitt@enPeop& :7609 ?% MN21 4933 ALLEN’S HATCHERY, INC.

... Dear Sir or Madam: The issues surrounding the availability of drugs for minor species and minor uses are many and varies depending on the species of animals involved. These comments are specifically concerning poultry. The first issue is: Can chicken and turkey breeder pullets be classified as minor ...
File
File

... Alleles are different forms of the same gene e.g. Blue eye colour, Brown eye colour Every body cell contains 2 matching sets of chromsomes (one set from each parent) Every body cell contains 2 alleles for a particular gene (one allele from each parent) The genotype is set of alleles that an organism ...
Prodrugs and active metabolites among antidepressive
Prodrugs and active metabolites among antidepressive

... individual drug response is in the focus of scientific interest it is worth to mention that individual genetic differences in drug metabolism may significantly modify drug response (Sárosi et al., 2008). Active metabolite(s) of drugs may significantly modify clinical effect as these metabolites may ...
FDA Advisory Panel Recommends Approval of Tysabri
FDA Advisory Panel Recommends Approval of Tysabri

... groups were treated for more than 2 years. Among patients treated with the active drug, the rate of clinical relapse was diminished by 68% and the number of new or enhancing MRI lesions was reduced by 83%. This was a striking improvement over other drugs for treatment of MS, which have been shown to ...
I Can PresCribE A Drug: Mnemonic
I Can PresCribE A Drug: Mnemonic

... therapy to ensure that all potential precautions have been considered. Third, the learner considers the patient’s medical history and other drug therapy the patient may be taking to ascertain if there are any significant drug-disease or drugdrug interactions with the therapeutic option in question. D ...
Topical Pain M Topical Pain Medications
Topical Pain M Topical Pain Medications

... base is used to assist the medications dications penetration through the skin. How to use Topical Pain Medications Use as directed by your health care provider. Please see your prescription for specific instructions. The following instructions are general guidelines. ...
Pharmacotherapy in the Elderly
Pharmacotherapy in the Elderly

... • Pharmacodynamic changes: vitamin K-dependent clotting factors deficiency • Pharmacokinetic changes: anticoagulants such as warfarin have a very narrow therapeutic window and are highly protein bound • drug interactions (eg., phenytoin) • adverse effect: excessive internal bleeding • Frequent monit ...
Drug Testing - ACL Laboratories
Drug Testing - ACL Laboratories

... topical analgesics such as Novocain, Xylocaine (lidocaine), benzocaine, etc. Although these compounds have analgesic properties, there is no structural similarity to cocaine or its metabolite (benzoylecgonine). Marijuana (THC) Prescription medication that contains delta-9-tetrahydronnabinol (THC): D ...
consisting of diuretics to remove excess water, beta blockers and
consisting of diuretics to remove excess water, beta blockers and

... We believe that this clinical candidate will be effective in the management of hyperkinetic movement disorders characterized by involuntary bodily movements as seen in patients suffering from Tardive Dyskinesia, and Huntington’s disease. Additionally, the modulation of dopamine pathways may also be ...
K2/Spice, Bath Salts, and other drugs, Vinnie Happ
K2/Spice, Bath Salts, and other drugs, Vinnie Happ

... results of 143 lab tests over the past four years of substances suspected of being Molly. Only 13% of the drugs were MDMA, while 41% were 4-MEC, a type of bath salt, and 20% were methylone. Veteran MDMA users say they ask that drugs be tested before they buy them, using kits that can be bought onlin ...
AMERICAN ACADEMY OF PEDIATRICS Uses of Drugs Not
AMERICAN ACADEMY OF PEDIATRICS Uses of Drugs Not

... medwatch). The law requires manufacturers to report all adverse experience reports they receive or are aware of (eg, published literature) to the FDA. Promising new uses for approved drugs might best be reported to the drug sponsor to encourage formal investigation. The full and ultimate role of a d ...
MENDEL AND THE GENE IDEA - Bio-Guru
MENDEL AND THE GENE IDEA - Bio-Guru

... With three or four or more pairs of genes, the phenotype distribution begins to resemble a bell-shaped curve; then it's easier to estimate or ...
Prescott`s Microbiology, 9th Edition 9 Antimicrobial Chemotherapy
Prescott`s Microbiology, 9th Edition 9 Antimicrobial Chemotherapy

... A. Inhibitors of cell wall synthesis are effective and selective because bacterial cell walls have unique structures not found in eukaryotic cells 1. Penicillins—inhibit cell wall synthesis; many types have been identified or synthesized including ampicillin, carbenicillin, and methicillin; they dif ...
April 1992 - North Carolina Board of Pharmacy
April 1992 - North Carolina Board of Pharmacy

... socia ted with either low-dose prolonged treatment OJ.' '.-,,cit!. moderate-to-high rlose treatments of varying duration:~. Because the Agency is concerned about this selious lIlcdl cal situation, FDA is requesting that all manufacturers of oraL injected, and inhaled corticosteroids include the foll ...
Hardy Weinberg Principle (equilibrium)
Hardy Weinberg Principle (equilibrium)

... Allelic frequencies in a gene pool will change due to natural selection of variations. ...
Nasal Drug Delivery in EMS
Nasal Drug Delivery in EMS

...  After an IV is established, naloxone (Narcan) is administered and the patient is successfully resuscitated.  Unfortunately, the medic suffers a contaminated needle stick while establishing the IV.  The patient admits to being infected with both HIV and hepatitis C. He remains alert for 2 hours ...
Maypole Health Centre PPG Meeting Drs Yap, Hughes and Michael
Maypole Health Centre PPG Meeting Drs Yap, Hughes and Michael

... Mr Cook asked when there would be available appointments on line for the Practice Nurse and Phlebotomist. Mike to look into this. Receptions are asking patients when booking in if they have registered for the online services. The partners are also asking the patients on consultation. Bowel Screenin ...
Happy New Year from the Medicine Management Team Community
Happy New Year from the Medicine Management Team Community

... Just In Case Boxes aim to improve identification of ‘Pre-emptive Medication’ within the patient’s home and to allow for safe and appropriate storage. As a collaborative approach Doncaster CCG has provided the boxes to DBHFT, RDaSH and those community pharmacies taking part in the palliative care LES ...
Guidelines
Guidelines

... 4) Patient is planning pregnancy via in vitro fertilization 5) Patient has already had a trial of an ovulation induction medication in the last ...
Copyright of the University of East Anglia
Copyright of the University of East Anglia

... Pharmacists play an important role in identifying and managing drug interactions. With respect to drug interactions: (a) Define pharmacokinetic and pharmacodynamics interactions, giving examples of each type. ...
GENERAL PRINCIPLES OF PHARMACOLOGY
GENERAL PRINCIPLES OF PHARMACOLOGY

... effect, two drugs with the same effect are given together — similar to 1+1=2.  Synergism—two drugs with the same effect are given together and produce a response greater than the sum of their individual responses — similar to 1+2=3. ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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