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research Nerve Cells, Axons, Dendrites, and Synapses: The
research Nerve Cells, Axons, Dendrites, and Synapses: The

... A synapse is a contact point of one neuron to the next neuron. The electrical impulse from one neuron travels down its axon and when it reaches the end, it activates a chemical transmitter that carries the impulse across a small gap to the next nerve cell. The component containing the gap is the syn ...
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... stimulus. In other words, the CS no longer elicits the CR. ◦ To acquire a CR, we repeatedly pair a neutral stimulus with the UCS. But, if we want to reverse this learning, we must weaken the strength of the connection between the two stimuli. For example, once the dogs have been conditioned to saliv ...
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... brainstem through the cerebellar peduncles to the deep cerebellar nuclei and cerebellar cortex. Each climbing fiber enters the molecular layer and makes up to several hundred synaptic contacts on dendrites of a single Purkinje cell. The mossy fibers branch profusely and, through synapses, exert exci ...
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48 0007-4888/05/14010048 © 2005 Springer Science+Business

... increased inhibition (for example, enhanced release of the transmitter [11] or enhanced regulation of postsynaptic GABAergic receptors [6]). The data on the direction of changes in the GABAergic system of patients with epilepsy of the parietal lobe also attest to decreased, retained, or increased GA ...
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Eyeblink conditioning

Eyeblink conditioning (EBC) is a form of classical conditioning that has been used extensively to study neural structures and mechanisms that underlie learning and memory. The procedure is relatively simple and usually consists of pairing an auditory or visual stimulus (the conditioned stimulus (CS)) with an eyeblink-eliciting unconditioned stimulus (US) (e.g. a mild puff of air to the cornea or a mild shock). Naïve organisms initially produce a reflexive, unconditioned response (UR) (e.g. blink or extension of nictitating membrane) that follows US onset. After many CS-US pairings, an association is formed such that a learned blink, or conditioned response (CR), occurs and precedes US onset. The magnitude of learning is generally gauged by the percentage of all paired CS-US trials that result in a CR. Under optimal conditions, well-trained animals produce a high percentage of CRs (> 90%). The conditions necessary for, and the physiological mechanisms that govern, eyeblink CR learning have been studied across many mammalian species, including mice, rats, guinea pigs, rabbits, ferrets, cats, and humans. Historically, rabbits have been the most popular research subjects.
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