PowerPoint-Präsentation
... data was performed using Genome-Studio (Illumina). Gene expression data were collected from Affymetrix HG-U133Plus 2.0 transcriptomes analysed in the BioRetis database. Mapping of CpG sites with genes was performed using the ensemble genome assembly GRCh37 genomic location map. ...
... data was performed using Genome-Studio (Illumina). Gene expression data were collected from Affymetrix HG-U133Plus 2.0 transcriptomes analysed in the BioRetis database. Mapping of CpG sites with genes was performed using the ensemble genome assembly GRCh37 genomic location map. ...
ap: chapter 16: the molecular basis of inheritance
... 1. After Morgan and fellow scientists developed the Chromosomal Theory of Inheritance, the search was on for the chemical mechanism of inheritance. What are the two components of the chromosome? __________________________________________________________________________ 2. From initial logic, which c ...
... 1. After Morgan and fellow scientists developed the Chromosomal Theory of Inheritance, the search was on for the chemical mechanism of inheritance. What are the two components of the chromosome? __________________________________________________________________________ 2. From initial logic, which c ...
High resolution melting for methylation analysis
... introducing functional inequality between two parental alleles of a gene ...
... introducing functional inequality between two parental alleles of a gene ...
DrMoran
... Long stretches of DNA make up genes. Genes make different things for our body. They are packaged up into chromosomes Chromosomes are like a big recipe box for our bodies and DNA is the recipe! ...
... Long stretches of DNA make up genes. Genes make different things for our body. They are packaged up into chromosomes Chromosomes are like a big recipe box for our bodies and DNA is the recipe! ...
RNA-Seq Analysis Practicals
... – Individual calls for single cytosines – Useful for looking at methylation patterns ...
... – Individual calls for single cytosines – Useful for looking at methylation patterns ...
DNA to Protein - Duplin County Schools
... http://www.classzone.com/cz/books/bio_07/resources/htmls/interactive_review/bio_intrev.html ...
... http://www.classzone.com/cz/books/bio_07/resources/htmls/interactive_review/bio_intrev.html ...
3-10
... Subject: The structure and replication of DNA. Reading in ‘An introduction to genetic analysis’ (Griffiths et al., 7th edition) Chapter 8: The structure and replication of DNA. ________________________________________________________________________ Key concepts and keywords: DNA: the genetic materi ...
... Subject: The structure and replication of DNA. Reading in ‘An introduction to genetic analysis’ (Griffiths et al., 7th edition) Chapter 8: The structure and replication of DNA. ________________________________________________________________________ Key concepts and keywords: DNA: the genetic materi ...
Introduction Aim TE presence/absence variant discovery Abundant
... Transposable element (TE) activity is silenced through DNA methylation A large fraction of genetic differences between individuals is due to TE presence/absence variants It is challenging to identify TE presence/absence variants from short read DNA sequencing data ...
... Transposable element (TE) activity is silenced through DNA methylation A large fraction of genetic differences between individuals is due to TE presence/absence variants It is challenging to identify TE presence/absence variants from short read DNA sequencing data ...
12.2 DNA Replication ppt
... All somatic cells that undergo mitosis get a new strand of DNA and an “old” one This occurs in the S phase of interphase Cannot be accomplished without the aid of enzymes. ...
... All somatic cells that undergo mitosis get a new strand of DNA and an “old” one This occurs in the S phase of interphase Cannot be accomplished without the aid of enzymes. ...
Klinisches Fehler- und Risikomanagement
... [1] Kucharski R et al.: Nutritional control of reproductive status in honeybees via DNA methylation. Science 319:1827-1830 (2008) ...
... [1] Kucharski R et al.: Nutritional control of reproductive status in honeybees via DNA methylation. Science 319:1827-1830 (2008) ...
DOC
... 6. What is the specific role of exonuclease-1 in this type of DNA repair? That is, which step does it accomplish? After a mismatch is identified and a nick introduced, EXO1 cuts out a section of the DNA strand containing the mismatched base. 7. How do E. coli distinguish between parental and newly r ...
... 6. What is the specific role of exonuclease-1 in this type of DNA repair? That is, which step does it accomplish? After a mismatch is identified and a nick introduced, EXO1 cuts out a section of the DNA strand containing the mismatched base. 7. How do E. coli distinguish between parental and newly r ...
Establishment of Cell Identity in Drosophila Embryos
... from Cedar and Bergman, Nature Rev.Genet. 10, 295 (2009) Repressive histone methylation marks must be removed, followed by removal of DNA methylation which activates the gene ...
... from Cedar and Bergman, Nature Rev.Genet. 10, 295 (2009) Repressive histone methylation marks must be removed, followed by removal of DNA methylation which activates the gene ...
Laboratory of Insect Genetics and Biosciences (IGB) Dept. Biology
... the DNA of mammalian somatic cells”. A recent paper showed the existence of non-CG methylation in mammalian somatic cells (PMID:26030523). In fact, non-CG methylation in mammals seems to be more informative of gene expression than CG methylation. R: It is true that DNA methylation has been detected ...
... the DNA of mammalian somatic cells”. A recent paper showed the existence of non-CG methylation in mammalian somatic cells (PMID:26030523). In fact, non-CG methylation in mammals seems to be more informative of gene expression than CG methylation. R: It is true that DNA methylation has been detected ...
DNA methylation
... histone variants – Facultative – repressive histone modifications, high DNA methylation ...
... histone variants – Facultative – repressive histone modifications, high DNA methylation ...
Use the diagram to match the letter (A-C) to the correct term(1
... Use the diagram to match the letter (W-Z) to the correct term(4-7). 4. ______ Complementary base pair. 5. ______ Hydrogen bond. 6. ______ Individual nitrogen base. 7. ______ Sugar-phosphate backbone. 8. In DNA, which of the following determines the traits of an organism? a. Amount of adenine b. Numb ...
... Use the diagram to match the letter (W-Z) to the correct term(4-7). 4. ______ Complementary base pair. 5. ______ Hydrogen bond. 6. ______ Individual nitrogen base. 7. ______ Sugar-phosphate backbone. 8. In DNA, which of the following determines the traits of an organism? a. Amount of adenine b. Numb ...
13 4 (a) Genetic modification of organisms uses a
... A vector to introduce foreign DNA into animal cells ............... ...
... A vector to introduce foreign DNA into animal cells ............... ...
Drs. Xiangqin Cui and Rui Feng Awarded Faculty Development Grant
... Drs. Xiangqin Cui and Rui Feng Awarded Faculty Development Grant July 22, 2008 Kudos go to Drs. Xiangqin Cui and Rui Feng who have been awarded a $30,000 Faculty Development Grant for the 2008-09 academic year for their proposal, entitled “Toward the Integration of Genomics and Epigenomics – a Pilot ...
... Drs. Xiangqin Cui and Rui Feng Awarded Faculty Development Grant July 22, 2008 Kudos go to Drs. Xiangqin Cui and Rui Feng who have been awarded a $30,000 Faculty Development Grant for the 2008-09 academic year for their proposal, entitled “Toward the Integration of Genomics and Epigenomics – a Pilot ...
Epigenetics-2015
... DNA Methylation Dynamics During Epigenetic Reprogramming Epigenetic memory must be erased for cells to achieve pleuripotency ...
... DNA Methylation Dynamics During Epigenetic Reprogramming Epigenetic memory must be erased for cells to achieve pleuripotency ...
Aslibekyan and team identify novel loci associated with BMI and
... assistant professor Degui Zhi, PhD, and professor Hemant K. Tiwari, PhD, in the Department of Biostatistics, Section on Statistical Genetics. The study measured DNA methylation patterns in CD4+ T-cells using the Illumina Infinium HumanMethylation450 array in a total of 991 participants of the Geneti ...
... assistant professor Degui Zhi, PhD, and professor Hemant K. Tiwari, PhD, in the Department of Biostatistics, Section on Statistical Genetics. The study measured DNA methylation patterns in CD4+ T-cells using the Illumina Infinium HumanMethylation450 array in a total of 991 participants of the Geneti ...
Cytosine – ______ Sugar
... 6. If 31.5% of a cell’s DNA is composed of adenine nucleotides, what are the percentages of the other three types of ...
... 6. If 31.5% of a cell’s DNA is composed of adenine nucleotides, what are the percentages of the other three types of ...
Genomic Organization in Eukaryotes
... • Addition of methyl groups (-CH3) to bases of DNA… • Many plants and animals do this, and it seems to be long-term control of gene expression. • In eukaryotes, genes that are not expressed (like Barr bodies) are more heavily methylated • Methylation ensures that once gene is turned off, it stays of ...
... • Addition of methyl groups (-CH3) to bases of DNA… • Many plants and animals do this, and it seems to be long-term control of gene expression. • In eukaryotes, genes that are not expressed (like Barr bodies) are more heavily methylated • Methylation ensures that once gene is turned off, it stays of ...
File
... 7. Nucleic Acids (AHL) – 7.2 Transcription & Gene Expression Name: 7.2.A1 The promoter as an example of non-coding DNA with a function. 1. Coding regions are used as a guide for the production of polypeptides, but non-coding regions are not. Non-coding regions do however have important functions, fo ...
... 7. Nucleic Acids (AHL) – 7.2 Transcription & Gene Expression Name: 7.2.A1 The promoter as an example of non-coding DNA with a function. 1. Coding regions are used as a guide for the production of polypeptides, but non-coding regions are not. Non-coding regions do however have important functions, fo ...
DNA methylation
DNA methylation is a process by which methyl groups are added to DNA. Methylation modifies the function of the DNA, typically acting to suppress gene transcription. DNA methylation is essential for normal development and is associated with a number of key processes including genomic imprinting, X-chromosome inactivation, suppression of repetitive elements, and carcinogenesis.Two of DNA's four nucleotides, cytosine and adenine, can be methylated. Adenine methylation is restricted to prokaryotes.The rate of cytosine DNA methylation differs strongly between species: 14% of cytosines are methylated in Arabidopsis thaliana, 4% in Mus musculus, 2.3% in Escherichia coli, 0.03% in Drosophila, and virtually none (< 0.0002%) in yeast species.DNA methylation can stably alter the expression of genes in cells as cells divide and differentiate from embryonic stem cells into specific tissues. The resulting change is normally permanent and unidirectional, preventing a cell from reverting to a stem cell or converting into a different cell type. However, DNA methylation can be removed either passively, by dilution as cells divide, or by a faster, active, process. The latter process occurs via hydroxylation of the methyl groups that are to be removed, rather than by complete removal of methyl groups. DNA methylation is typically removed during zygote formation and re-established through successive cell divisions during development. Methylation modifications that regulate gene expression are usually heritable through mitotic cell division; some methylation is also heritable through the specialized meiotic cell division that creates egg and sperm cells, resulting in genomic imprinting. DNA methylation suppresses the expression of endogenous retroviral genes and other harmful stretches of DNA that have been incorporated into the host genome over time. DNA methylation also forms the basis of chromatin structure, which enables a single cell to grow into multiple organs or perform multiple functions. DNA methylation also plays a crucial role in the development of nearly all types of cancer.DNA methylation at the 5 position of cytosine has the specific effect of reducing gene expression and has been found in every vertebrate examined. In adult somatic cells (cells in the body, not used for reproduction), DNA methylation typically occurs in a CpG dinucleotide context; non-CpG methylation is prevalent in embryonic stem cells, and has also been indicated in neural development.