Noninvasive and invasive evaluation of pulmonary arterial pressure in highlanders
... In total, 60 (55 male) patients aged 18–71 yrs were recruited from an ECG screening programme applied to 1,430 inhabitants living at an altitude of 2,500–3,600 m in Kyrgyzstan. Of these, 44 met ECG criteria for right ventricular hypertrophy. All underwent Doppler echocardiography followed by a cardi ...
... In total, 60 (55 male) patients aged 18–71 yrs were recruited from an ECG screening programme applied to 1,430 inhabitants living at an altitude of 2,500–3,600 m in Kyrgyzstan. Of these, 44 met ECG criteria for right ventricular hypertrophy. All underwent Doppler echocardiography followed by a cardi ...
The Impact of ST Elevation on Athletic Screening
... single-lead criteria compared with the adjacent-lead criteria, so the following figures will only show the results for the singlelead criteria. As shown, the prevalence of STE decreases with age, is more prevalent in athletes compared with age-matched outpatients, and is 2 to 10 times more prevalent ...
... single-lead criteria compared with the adjacent-lead criteria, so the following figures will only show the results for the singlelead criteria. As shown, the prevalence of STE decreases with age, is more prevalent in athletes compared with age-matched outpatients, and is 2 to 10 times more prevalent ...
Surgical Ablation of Atrial Fibrillation during Mitral
... 6.8% in the ablation group and 8.7% in the control group (hazard ratio with ablation, 0.76; 95% confidence interval, 0.32 to 1.84; P = 0.55). Ablation was associated with more implantations of a permanent pacemaker than was no ablation (21.5 vs. 8.1 per 100 patient-years, P = 0.01). There were no si ...
... 6.8% in the ablation group and 8.7% in the control group (hazard ratio with ablation, 0.76; 95% confidence interval, 0.32 to 1.84; P = 0.55). Ablation was associated with more implantations of a permanent pacemaker than was no ablation (21.5 vs. 8.1 per 100 patient-years, P = 0.01). There were no si ...
Chapter 3
... • Cardiac muscle relies on aerobic cellular respiration for ATP production. • Cardiac muscle also produces some ATP from creatine phosphate • The presence of creatine kinase (CK) in the blood indicates injury of cardiac muscle usually caused by a myocardial infarction. ...
... • Cardiac muscle relies on aerobic cellular respiration for ATP production. • Cardiac muscle also produces some ATP from creatine phosphate • The presence of creatine kinase (CK) in the blood indicates injury of cardiac muscle usually caused by a myocardial infarction. ...
PREVALENCE OF LEFT VENTRICULAR HYPERTROPHY AND ITS
... who helped me during various phases of this work. Last but not least, I wish to express my utmost gratitude to my wife Amana, my daughters Salha and Samira and my son Imran for their constant tireless encouragement and inspiration during the dark hours of this work. ...
... who helped me during various phases of this work. Last but not least, I wish to express my utmost gratitude to my wife Amana, my daughters Salha and Samira and my son Imran for their constant tireless encouragement and inspiration during the dark hours of this work. ...
Do clinically relevant transthoracic defibrillation energies cause
... defibrillation setting where the patients’ size and shape vary, placement of the defibrillation patches vary, and the etiology of their arrhythmia varies. Unlike internal defibrillators, which are tested at implantation, efficacy of an external defibrillator is determined only once, when it is most ...
... defibrillation setting where the patients’ size and shape vary, placement of the defibrillation patches vary, and the etiology of their arrhythmia varies. Unlike internal defibrillators, which are tested at implantation, efficacy of an external defibrillator is determined only once, when it is most ...
A case with pyopericardium and cardiac tamponade
... perforated the ventricular wall and subsequently migrated into the pericardial cavity. In both of these cases, gradual erosion of the atrial or ventricular wall caused by the distal tip of the VA shunt was one of the main sources of the cardiac tamponade. However, to our knowledge, there are no prev ...
... perforated the ventricular wall and subsequently migrated into the pericardial cavity. In both of these cases, gradual erosion of the atrial or ventricular wall caused by the distal tip of the VA shunt was one of the main sources of the cardiac tamponade. However, to our knowledge, there are no prev ...
Natriuretic Peptides in the Regulation of Cardiovascular Physiology
... system. The discovery of natriuretic peptides (NPs) dates back to 1981, when de Bold et al. found that administration of atrial extracts into intact rats causes diuresis and natriuresis.1 In 1983–1984, ANP was then isolated and purified, and the amino acid sequence was determined in rats and humans. ...
... system. The discovery of natriuretic peptides (NPs) dates back to 1981, when de Bold et al. found that administration of atrial extracts into intact rats causes diuresis and natriuresis.1 In 1983–1984, ANP was then isolated and purified, and the amino acid sequence was determined in rats and humans. ...
A healthy heart is not a metronome
... vagal innervation of the ventricles, vagal activity minimally affects ventricular contractility. The response time of the sinus node is very short and the effect of a single efferent vagal impulse depends on the phase of the cardiac cycle at which it is received. Thus, vagal stimulation results in a ...
... vagal innervation of the ventricles, vagal activity minimally affects ventricular contractility. The response time of the sinus node is very short and the effect of a single efferent vagal impulse depends on the phase of the cardiac cycle at which it is received. Thus, vagal stimulation results in a ...
Full Text:PDF - The Turkish Journal of Pediatrics
... In conclusion, palpitations or symptoms suggesting tachyarrhythmia in infants need an evaluation of the mechanism of arrhythmia because the course, prognosis and treatment of separate tachyarrhythmias are different. In the absence of structural heart disease, atrial tachyarrhythmias are common arrhy ...
... In conclusion, palpitations or symptoms suggesting tachyarrhythmia in infants need an evaluation of the mechanism of arrhythmia because the course, prognosis and treatment of separate tachyarrhythmias are different. In the absence of structural heart disease, atrial tachyarrhythmias are common arrhy ...
Balloon Pulmonary Valvuloplasty in Adults with Congenital Valvular
... tract and rase its pressure gradient.39 Cases of infundibular spasm after BPV were reported by Al-Kasab et al.18 However, among our patients, we did not find such conditions occurring. In addition, RV infundibular hypertrophy secondary to PS usually regresses gradually after the procedure of BPV, wh ...
... tract and rase its pressure gradient.39 Cases of infundibular spasm after BPV were reported by Al-Kasab et al.18 However, among our patients, we did not find such conditions occurring. In addition, RV infundibular hypertrophy secondary to PS usually regresses gradually after the procedure of BPV, wh ...
Multiple Coronary Artery-Left Ventricular Fistulas Associated With
... ischemia in the long term. However, we have seen prostacyclin aggravate chest pain in patients with PPH and be associated with worsening left ventricular function, the basis of which has never been explored. The management of patients with pulmonary hypertension is difficult and their prognosis is g ...
... ischemia in the long term. However, we have seen prostacyclin aggravate chest pain in patients with PPH and be associated with worsening left ventricular function, the basis of which has never been explored. The management of patients with pulmonary hypertension is difficult and their prognosis is g ...
Introducing a novel mechanism to control heart rate in the ancestral
... adrenergic tonus acting presumably on the primary cardiac pacemaker cells located in the sinoatrial node, which would set the intrinsic cardiac pacemaker rate (Farrell, 2007). To date, the sinoatrial node has not been identified in any hagfish species, but is presumed to be present in Eptatretus cir ...
... adrenergic tonus acting presumably on the primary cardiac pacemaker cells located in the sinoatrial node, which would set the intrinsic cardiac pacemaker rate (Farrell, 2007). To date, the sinoatrial node has not been identified in any hagfish species, but is presumed to be present in Eptatretus cir ...
Survival Benefit of Aortic Valve Replacement in Patients With Severe
... This retrospective cohort study from a large university medical center was approved by our local institutional review board, which waived the need for patient consent because of the retrospective study nature. The echocardiographic database was searched for patients with severe aortic stenosis defin ...
... This retrospective cohort study from a large university medical center was approved by our local institutional review board, which waived the need for patient consent because of the retrospective study nature. The echocardiographic database was searched for patients with severe aortic stenosis defin ...
Causes of sudden death in competitive athletes
... hypertrophy was symmetric (concentric); 2) disorganization of cardiac muscle cells was not present in left ventricular myocardium (15); and 3) there was no clinical or echocar• diographic evidence of genetic transmission of hypertrophic cardiomyopathy in first degree relatives (7). Some athletes wit ...
... hypertrophy was symmetric (concentric); 2) disorganization of cardiac muscle cells was not present in left ventricular myocardium (15); and 3) there was no clinical or echocar• diographic evidence of genetic transmission of hypertrophic cardiomyopathy in first degree relatives (7). Some athletes wit ...
Kavasmaa, Mervi Haapsamo, Luc Mertens and James
... in a model of increased Rua. All experiments were performed in accordance with the guidelines of the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (1986) and in compliance with European Union Directive 86/609/EEC (1997). The research ...
... in a model of increased Rua. All experiments were performed in accordance with the guidelines of the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (1986) and in compliance with European Union Directive 86/609/EEC (1997). The research ...
Heart Rate Recovery After Exercise and Long-term
... predictor of both long-term all-cause and CV mortality in a large CAD cohort. Similarly, in the threshold models, HRR ⬍ 46 Bpm at 3 minutes was independently associated with longterm all-cause mortality, while a statistical trend was noted for CV mortality. The novelty of this study is that it is th ...
... predictor of both long-term all-cause and CV mortality in a large CAD cohort. Similarly, in the threshold models, HRR ⬍ 46 Bpm at 3 minutes was independently associated with longterm all-cause mortality, while a statistical trend was noted for CV mortality. The novelty of this study is that it is th ...
Quantitative Estimation of Left Ventricular Ejection Fraction from
... This study tested the hypothesis that the mitral valve E point-to-septal separation (EPSS) can be used to quantify the left ventricular (LV) ejection fraction (EF) on a continuous scale rather than simply as “normal” or “reduced.” After excluding 5 patients with mitral valve prostheses, asymmetric s ...
... This study tested the hypothesis that the mitral valve E point-to-septal separation (EPSS) can be used to quantify the left ventricular (LV) ejection fraction (EF) on a continuous scale rather than simply as “normal” or “reduced.” After excluding 5 patients with mitral valve prostheses, asymmetric s ...
Effect of temporal resolution on the estimation of left ventricular
... Keywords: Magnetic resonance imaging; Heart; Left ventricular function; Temporal resolution ...
... Keywords: Magnetic resonance imaging; Heart; Left ventricular function; Temporal resolution ...
Myocardial infarction
... Creatine kinase can be further subdivided into three isoenzymes: MM, MB, and BB. The MM fraction is present in both cardiac and skeletal muscle, but the MB fraction is much more specific for cardiac muscle: about 15 to 40% of CK in cardiac muscle is MB, while less than 2% in skeletal muscle is MB. T ...
... Creatine kinase can be further subdivided into three isoenzymes: MM, MB, and BB. The MM fraction is present in both cardiac and skeletal muscle, but the MB fraction is much more specific for cardiac muscle: about 15 to 40% of CK in cardiac muscle is MB, while less than 2% in skeletal muscle is MB. T ...
Cardio-Oncology and stem cell transplant
... (HF), and a 7.0–15.9-fold increased risk of CVD risk factors such as hypertension, diabetes, and dyslipidemia (Baker et al., 2007, 2012; Chow et al., 2011; Tichelli et al., 2008a; Armenian et al., 2012, 2011a,b, 2010; Griffith et al., 2010). This excess CVD risk (Speck et al., 2010; Baker et al., 201 ...
... (HF), and a 7.0–15.9-fold increased risk of CVD risk factors such as hypertension, diabetes, and dyslipidemia (Baker et al., 2007, 2012; Chow et al., 2011; Tichelli et al., 2008a; Armenian et al., 2012, 2011a,b, 2010; Griffith et al., 2010). This excess CVD risk (Speck et al., 2010; Baker et al., 201 ...
Is Epinephrine During Cardiac Arrest Associated With Worse Outcomes in Resuscitated Patients?
... of this drug on recovery during the post–cardiac arrest phase is debatable. OBJECTIVES This study sought to investigate the relationship between pre-hospital use of epinephrine and functional survival among patients with out-of-hospital cardiac arrest (OHCA) who achieved successful ROSC. METHODS We ...
... of this drug on recovery during the post–cardiac arrest phase is debatable. OBJECTIVES This study sought to investigate the relationship between pre-hospital use of epinephrine and functional survival among patients with out-of-hospital cardiac arrest (OHCA) who achieved successful ROSC. METHODS We ...
Magnitude of myocardial dysfunction is greater in painful than in
... had diagnostic coronary arteriography within 3 weeks of exercise echocardiography with demonstration of significant coronary artery disease (>70% diameter narrowing of at least one coronary artery). All antianginal therapy was discontinued at least 24 h before the exercise tests. Exercise electrocar ...
... had diagnostic coronary arteriography within 3 weeks of exercise echocardiography with demonstration of significant coronary artery disease (>70% diameter narrowing of at least one coronary artery). All antianginal therapy was discontinued at least 24 h before the exercise tests. Exercise electrocar ...
Should All Patients With Heart Block Receive Biventricular Pacing?
... entricular pacing can be lifesaving for patients with complete atrioventricular block (AVB). Since the introduction of permanent transvenous cardiac pacing >40 years ago, the right ventricular (RV) apex has been the preferred site for ventricular stimulation. This location provides good fixation and ...
... entricular pacing can be lifesaving for patients with complete atrioventricular block (AVB). Since the introduction of permanent transvenous cardiac pacing >40 years ago, the right ventricular (RV) apex has been the preferred site for ventricular stimulation. This location provides good fixation and ...
Cardiac contractility modulation
.jpg?width=300)
Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.