PDF - Circulation
... After a minimum ventricular fibrillation of 10 seconds, defibrillation was attempted. The defibrillation threshold was determined as follows. The initial defibrillation setting was at a stored voltage of 300 V, which corresponded to an estimated energy delivery of approximately 3 J. Subsequent shock ...
... After a minimum ventricular fibrillation of 10 seconds, defibrillation was attempted. The defibrillation threshold was determined as follows. The initial defibrillation setting was at a stored voltage of 300 V, which corresponded to an estimated energy delivery of approximately 3 J. Subsequent shock ...
Effects of Ischemia and Hypercarbic Acidosis on Myocyte Calcium
... extravascular space. Indo-1 fluorescence was recorded from the epicardial surface of the left ventricle at an excitation wavelength of 360 nm and emission wavelengths of 400 and 550 nm. BCECF fluorescence was recorded at an excitation wavelength of 490 nm and an emission wavelength of 530 nm. Calibr ...
... extravascular space. Indo-1 fluorescence was recorded from the epicardial surface of the left ventricle at an excitation wavelength of 360 nm and emission wavelengths of 400 and 550 nm. BCECF fluorescence was recorded at an excitation wavelength of 490 nm and an emission wavelength of 530 nm. Calibr ...
ECG by Dr.Sarma for print
... Normal Resting ECG – cannot exclude disease Ischemia may be covert – supply / demand equation Changes of MI take some time to develop in ECG Mild Ventricular hypertrophy - not detectable in ECG Some of the ECG abnormalities are non specific Single ECG cannot give progress – Need serial ECGs ECG chan ...
... Normal Resting ECG – cannot exclude disease Ischemia may be covert – supply / demand equation Changes of MI take some time to develop in ECG Mild Ventricular hypertrophy - not detectable in ECG Some of the ECG abnormalities are non specific Single ECG cannot give progress – Need serial ECGs ECG chan ...
Mechanisms of Activation of Cardiac Glycogen Phosphorylase in
... ischemia induces phosphorylase a formation through a cyclic AMP—dependent transformation of phosphorylase kinase; however, in anoxia phosphorylase a formation depends only on the regulation of the catalytic activity of phosphorylase kinase without conversion of this enzyme to its activated form. An ...
... ischemia induces phosphorylase a formation through a cyclic AMP—dependent transformation of phosphorylase kinase; however, in anoxia phosphorylase a formation depends only on the regulation of the catalytic activity of phosphorylase kinase without conversion of this enzyme to its activated form. An ...
Aortic Dissection - Society of Cardiovascular Anesthesiologists
... functional mitral regurgitation, but evidence and expert opinion is controversial when the severity of ischemic mitral regurgitation is mild to moderate. At present, several randomized controlled trials have been performed to address this question. Even though the existing trials have not been adequ ...
... functional mitral regurgitation, but evidence and expert opinion is controversial when the severity of ischemic mitral regurgitation is mild to moderate. At present, several randomized controlled trials have been performed to address this question. Even though the existing trials have not been adequ ...
Pradyot Saklani, Andrew Krahn and George Klein Syncope doi
... Cardiac syncope is most often arrhythmic. Syncope during tachycardia is related to rate but modulated by the specific arrhythmia (supraventricular/ventricular), preload conditions, posture, left ventricular function, and adequacy of vascular adaptation.19 Sinus node dysfunction or AV block may cause ...
... Cardiac syncope is most often arrhythmic. Syncope during tachycardia is related to rate but modulated by the specific arrhythmia (supraventricular/ventricular), preload conditions, posture, left ventricular function, and adequacy of vascular adaptation.19 Sinus node dysfunction or AV block may cause ...
Infarct Size and Myocardial Function
... The segmented scar sequence ‐ inversion recovery fast gradient echo, IR_FGRE, is a well documented sequence for scar determination, however, the sequence requires regular heart rhythm and breath holding for good imaging. We showed that a single shot scar sequence ‐ steady state ...
... The segmented scar sequence ‐ inversion recovery fast gradient echo, IR_FGRE, is a well documented sequence for scar determination, however, the sequence requires regular heart rhythm and breath holding for good imaging. We showed that a single shot scar sequence ‐ steady state ...
Coronary - Diagnostic and Interventional Radiology
... pulmonary artery originates from this ventricle. This chamber has papillary muscles and a smooth septal wall. The LA empties into the ventricle located on the left (morphologically, the right ventricle [RV]) through the tricuspid valve, and the aorta arises from this ventricle. This ventricle has pr ...
... pulmonary artery originates from this ventricle. This chamber has papillary muscles and a smooth septal wall. The LA empties into the ventricle located on the left (morphologically, the right ventricle [RV]) through the tricuspid valve, and the aorta arises from this ventricle. This ventricle has pr ...
INCIDENCE, PREDICTORS AND OUTCOMES OF MYOCARDIAL
... the introduction of large catheters through it. Accordingly, nearly all patients undergoing TAVR present some degree of myocardial injury, as defined by any increase in cardiac biomarkers, including creatine kinase-MB (CK-MB), troponin or B-type natriuretic peptides (BNP). Nonetheless, data on the e ...
... the introduction of large catheters through it. Accordingly, nearly all patients undergoing TAVR present some degree of myocardial injury, as defined by any increase in cardiac biomarkers, including creatine kinase-MB (CK-MB), troponin or B-type natriuretic peptides (BNP). Nonetheless, data on the e ...
Task Force Report Guidelines on management (diagnosis and treatment) of syncope*
... A major issue in the use of diagnostic tests is that syncope is a transient symptom and not a disease. Typically patients are asymptomatic at the time of evaluation and the opportunity to capture a spontaneous event during diagnostic testing is rare. As a result, the diagnostic evaluation has focuse ...
... A major issue in the use of diagnostic tests is that syncope is a transient symptom and not a disease. Typically patients are asymptomatic at the time of evaluation and the opportunity to capture a spontaneous event during diagnostic testing is rare. As a result, the diagnostic evaluation has focuse ...
Invasive Hemodynamic Characteristics of Low Gradient
... contents of this paper to disclose. The first 2 authors contributed equally to this work. Manuscript received December 3, 2012; manuscript revised January 29, 2013, accepted February 3, 2013. ...
... contents of this paper to disclose. The first 2 authors contributed equally to this work. Manuscript received December 3, 2012; manuscript revised January 29, 2013, accepted February 3, 2013. ...
Cross-Talk Between Cardiac Muscle and Coronary Vasculature
... and Coronary Vasculature. Physiol Rev 86: 1263–1308, 2006; doi:10.1152/physrev.00029.2005.—The cardiac muscle and the coronary vasculature are in close proximity to each other, and a two-way interaction, called cross-talk, exists. Here we focus on the mechanical aspects of cross-talk including the r ...
... and Coronary Vasculature. Physiol Rev 86: 1263–1308, 2006; doi:10.1152/physrev.00029.2005.—The cardiac muscle and the coronary vasculature are in close proximity to each other, and a two-way interaction, called cross-talk, exists. Here we focus on the mechanical aspects of cross-talk including the r ...
Aortic Stenosis In The Elderly
... wall stress in patients with aortic stenosis. However, increased left ventricular stiffness results, with a subsequent rise in left ventricular filling pressure, and pulmonary congestion develops, especially during exercise. As the left ventricular wall stiffens, the importance of normal sinus rhyth ...
... wall stress in patients with aortic stenosis. However, increased left ventricular stiffness results, with a subsequent rise in left ventricular filling pressure, and pulmonary congestion develops, especially during exercise. As the left ventricular wall stiffens, the importance of normal sinus rhyth ...
Smith, Jr, John A. Spertus and Sankey V. Williams Prager, Joseph F
... Expert peer review of AHA Scientific Statements is conducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit http://my.americanheart.org/statements and select the “Policies and Development” link. Permissions: Multiple copies, modification, altera ...
... Expert peer review of AHA Scientific Statements is conducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit http://my.americanheart.org/statements and select the “Policies and Development” link. Permissions: Multiple copies, modification, altera ...
Atrial Remodeling and Atrial Fibrillation
... circuit path space so that larger reentry circuits can be supported (left) and/or a larger number of circuits can be maintained (right). RP indicates refractory period. ...
... circuit path space so that larger reentry circuits can be supported (left) and/or a larger number of circuits can be maintained (right). RP indicates refractory period. ...
Effect of Ischemia on Calcium-Dependent Fluorescence
... The effects of acute global ischemia on cytosolic calcium transients were studied in perfused rabbit hearts loaded with the fluorescent calcium indicator indo 1. Indo 1-loaded hearts were illuminated at 360 nm, and fluorescence was recorded simultaneously at 400 and 550 nm from the epicardial surfac ...
... The effects of acute global ischemia on cytosolic calcium transients were studied in perfused rabbit hearts loaded with the fluorescent calcium indicator indo 1. Indo 1-loaded hearts were illuminated at 360 nm, and fluorescence was recorded simultaneously at 400 and 550 nm from the epicardial surfac ...
ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction
... is to develop and revise practice guidelines for important cardiovascular diseases and procedures. Experts in the subject under consideration are selected from both organizations to examine subject-specific data and write guidelines. The process includes additional representatives from other medical ...
... is to develop and revise practice guidelines for important cardiovascular diseases and procedures. Experts in the subject under consideration are selected from both organizations to examine subject-specific data and write guidelines. The process includes additional representatives from other medical ...
ACC/AHA 2004 STEMI Guidelines
... is to develop and revise practice guidelines for important cardiovascular diseases and procedures. Experts in the subject under consideration are selected from both organizations to examine subject-specific data and write guidelines. The process includes additional representatives from other medical ...
... is to develop and revise practice guidelines for important cardiovascular diseases and procedures. Experts in the subject under consideration are selected from both organizations to examine subject-specific data and write guidelines. The process includes additional representatives from other medical ...
guideline-for-prevention-of-ais-in-patients-with-stroke-or-tia
... with placebo in high-risk persons and found a 24% risk reduction (95% CI, 5 to 40) for stroke, MI, or vascular death among the 1013 patients with a history of stroke or TIA.14 Although the BP-lowering effect as measured during the study was minimal (average, 3/2 mm Hg), it may have been related to t ...
... with placebo in high-risk persons and found a 24% risk reduction (95% CI, 5 to 40) for stroke, MI, or vascular death among the 1013 patients with a history of stroke or TIA.14 Although the BP-lowering effect as measured during the study was minimal (average, 3/2 mm Hg), it may have been related to t ...
Amiodarone Hydrochloride 150 mg/3 mL Name of the
... therapeutic management. The treatment should be adjusted to each individual case: for example anti-thyroid medicines, corticosteroid therapy, beta-blockers. ...
... therapeutic management. The treatment should be adjusted to each individual case: for example anti-thyroid medicines, corticosteroid therapy, beta-blockers. ...
Contemporary Echocardiography In Non
... Results: Of 55 patients, 76% were male while 20% had diabetes and 56% were current or previous smokers. Patients with diabetes and/or smoking history were more likely to have multiple coronary lesions and nine fold more likely to require coronary artery bypass grafting. 36% of patients had a left ve ...
... Results: Of 55 patients, 76% were male while 20% had diabetes and 56% were current or previous smokers. Patients with diabetes and/or smoking history were more likely to have multiple coronary lesions and nine fold more likely to require coronary artery bypass grafting. 36% of patients had a left ve ...
Atrial natriuretic peptide (ANP)
... regarding the acute and chronic effects of the ANP release reduction and consequently abnormalities in the renal function related to body fluid control arising from cardiac surgeries where removal of the auricles is carried out. Furthermore, a number of clinical trials suggest that application of th ...
... regarding the acute and chronic effects of the ANP release reduction and consequently abnormalities in the renal function related to body fluid control arising from cardiac surgeries where removal of the auricles is carried out. Furthermore, a number of clinical trials suggest that application of th ...
The Mammalian Ste20-like Kinase 2 (Mst2) Modulates Stress
... (Fig. 1A). Because inhibition of Hippo pathway in embryonic hearts resulted in increased cardiomyocyte proliferation (8), we therefore analyzed cardiomyocyte proliferation in Mst2⫺/⫺ neonatal hearts. We examined hearts from 3-day-old WT and Mst2⫺/⫺ neonates and stained them with markers of cell mito ...
... (Fig. 1A). Because inhibition of Hippo pathway in embryonic hearts resulted in increased cardiomyocyte proliferation (8), we therefore analyzed cardiomyocyte proliferation in Mst2⫺/⫺ neonatal hearts. We examined hearts from 3-day-old WT and Mst2⫺/⫺ neonates and stained them with markers of cell mito ...
Thrombus aspiration for treating distal coronary macroemboli during
... coronary artery stenosis and coronary bifurcation macroemboli after insertion of the 0.014 inch floppy guidewire. Black arrows indicate coronary thrombosis of acute marginal branch and distal-RCA; C. Anteroposterior cranial angiographic view clearly demonstrates coronary bifurcation emboli. Black ar ...
... coronary artery stenosis and coronary bifurcation macroemboli after insertion of the 0.014 inch floppy guidewire. Black arrows indicate coronary thrombosis of acute marginal branch and distal-RCA; C. Anteroposterior cranial angiographic view clearly demonstrates coronary bifurcation emboli. Black ar ...
Mortality Study of the Significance of Extrasystoles in an
... persons who had been insured at standard rates for not more than 15 years and whose mortality was observed between 1955 and 1960 for each age and duration of exposure (the Male Intercompany 1955-1960 Basic Select Tables); and (b) persons who had been insured at standard rates at least 15-years prior ...
... persons who had been insured at standard rates for not more than 15 years and whose mortality was observed between 1955 and 1960 for each age and duration of exposure (the Male Intercompany 1955-1960 Basic Select Tables); and (b) persons who had been insured at standard rates at least 15-years prior ...
Cardiac contractility modulation
Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.