The role of Tbx2 in the development of the - UvA-DARE
... cell fate are often set, particularly in the embryo, by geographical or environmental parameters, such as the source and strength of a secreted inductive signal, and these may change with time. Anatomic patterns or landmarks provide vital clues to how we should think about development and indeed dis ...
... cell fate are often set, particularly in the embryo, by geographical or environmental parameters, such as the source and strength of a secreted inductive signal, and these may change with time. Anatomic patterns or landmarks provide vital clues to how we should think about development and indeed dis ...
"Nonspecific" ST Segment and T-Wave Changes
... changes could not be attributed to syrnpatheticotonia and is most probably a sign of coronary involvement. Partial changes are difficult to evaluate and remain doubtful. In our study, in those diagnosed definitely pathologic, the ECG did not return to normal in any patient. Among the 53 in whom we c ...
... changes could not be attributed to syrnpatheticotonia and is most probably a sign of coronary involvement. Partial changes are difficult to evaluate and remain doubtful. In our study, in those diagnosed definitely pathologic, the ECG did not return to normal in any patient. Among the 53 in whom we c ...
Amr Ali Esmail _Isoflurane_preconditioning
... midazolam group compared to levels estimated in isoflurane group. On contrary, plasma cTnT levels estimated in midazolam group at 16, 24, 36 and 48 hours after aortic crossclamping were significantly higher (P6=0.034, 0.01, <0.001 & =0.031, respectively) compared to levels estimated in isoflurane gr ...
... midazolam group compared to levels estimated in isoflurane group. On contrary, plasma cTnT levels estimated in midazolam group at 16, 24, 36 and 48 hours after aortic crossclamping were significantly higher (P6=0.034, 0.01, <0.001 & =0.031, respectively) compared to levels estimated in isoflurane gr ...
Long-term analysis of left ventricular ejection fraction in patients with
... in patients with documented myocardium ischaemia of greater extension and severity, the ongoing ISCHEMIA trial,12 will compare the efficacy of different therapeutic strategies is patients with moderate-to-severe ischaemia. Additionally, the role of revascularization procedures in regard to their pot ...
... in patients with documented myocardium ischaemia of greater extension and severity, the ongoing ISCHEMIA trial,12 will compare the efficacy of different therapeutic strategies is patients with moderate-to-severe ischaemia. Additionally, the role of revascularization procedures in regard to their pot ...
the PROCAMIO study
... well known and have been in conventional clinical use for decades,5 – 10 there is no scientific evidence to base the use of one drug vs. the other in this clinical context. Controlled trials with amiodarone have been performed in other clinical contexts11 – 14 (i.e. hypotensive VT or cardiac arrest) ...
... well known and have been in conventional clinical use for decades,5 – 10 there is no scientific evidence to base the use of one drug vs. the other in this clinical context. Controlled trials with amiodarone have been performed in other clinical contexts11 – 14 (i.e. hypotensive VT or cardiac arrest) ...
Understanding Ventricular Tachycardia: Towards Individualized
... was calculated. Variables with a p-value <0.10 were further evaluated in a multivariate model, using backward stepwise selection. At each step, the least significant variable was discarded from the model, until all variables in the model reached a p-value <0.25. The cumulative incidence of first spo ...
... was calculated. Variables with a p-value <0.10 were further evaluated in a multivariate model, using backward stepwise selection. At each step, the least significant variable was discarded from the model, until all variables in the model reached a p-value <0.25. The cumulative incidence of first spo ...
the velocity of blood flow, venous and arterial
... damage. As is well kiiown, auricular fibrillation itself is not necessarily the cause of the clinical signs and symptoms of circulatory decompensation. The exact degree to which the abnormal rhythm and the myocardial lesion each contributes to the decompensatory state must vary from individual to in ...
... damage. As is well kiiown, auricular fibrillation itself is not necessarily the cause of the clinical signs and symptoms of circulatory decompensation. The exact degree to which the abnormal rhythm and the myocardial lesion each contributes to the decompensatory state must vary from individual to in ...
New-Onset Complete Heart Block in the PACU
... pacing in patients with complete right bundle-branch block with axis deviation when surgical procedures are performed: 10year experience from a single Japanese university hospital. J Anesth (2009) 23:616–619 8. Gauss A, Hubner C, Meierhenrich R, Rohm HJ, Georgieff M, Schutz W. Perioperative transcut ...
... pacing in patients with complete right bundle-branch block with axis deviation when surgical procedures are performed: 10year experience from a single Japanese university hospital. J Anesth (2009) 23:616–619 8. Gauss A, Hubner C, Meierhenrich R, Rohm HJ, Georgieff M, Schutz W. Perioperative transcut ...
Ch18B
... (Slide 9) ________________________________________ coupling occurs as Ca2+ binds to troponin and sliding of the filaments begins. Duration of the Action Potential and the Contractile Phase is much ____________in __________________muscle than in ______________ muscle. _______________________ results ...
... (Slide 9) ________________________________________ coupling occurs as Ca2+ binds to troponin and sliding of the filaments begins. Duration of the Action Potential and the Contractile Phase is much ____________in __________________muscle than in ______________ muscle. _______________________ results ...
Evaluation of Right Ventricular Systolic Function by
... led to increase in pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR) and inverted shunt. Pre-tricuspid lesions (ASD) produce an increased flow in the pulmonary vascular bed and will show a lower and delayed occurrence of PAH than post tricuspid shunts (VSD or PDA) which produce a ...
... led to increase in pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR) and inverted shunt. Pre-tricuspid lesions (ASD) produce an increased flow in the pulmonary vascular bed and will show a lower and delayed occurrence of PAH than post tricuspid shunts (VSD or PDA) which produce a ...
CVS_Part1
... pain that occurs with progressively increasing frequency, is precipitated with progressively less effort, often occurs at rest, and tends to be of more prolonged duration. It is induced by disruption of an atherosclerotic plaque with superimposed partia) thrombosis and possibly embolization or vasos ...
... pain that occurs with progressively increasing frequency, is precipitated with progressively less effort, often occurs at rest, and tends to be of more prolonged duration. It is induced by disruption of an atherosclerotic plaque with superimposed partia) thrombosis and possibly embolization or vasos ...
Q21 Define preload and describe the determinants
... § Heart rate à the slower the heart rate the greater the filling time of diastole and the greater the preload § Atrial contraction à a change in atrial contraction due to sympathetic stimulation ...
... § Heart rate à the slower the heart rate the greater the filling time of diastole and the greater the preload § Atrial contraction à a change in atrial contraction due to sympathetic stimulation ...
the cardiovascular system: the heart
... and causing the cells to contract. Describe the timing of events that occur in the conduction system as depolarization sweeps across the heart muscle. At the beginning of a cardiac cycle, the SA node generates an action potential (0.00 sec). This action potential moves across the atrial muscle like ...
... and causing the cells to contract. Describe the timing of events that occur in the conduction system as depolarization sweeps across the heart muscle. At the beginning of a cardiac cycle, the SA node generates an action potential (0.00 sec). This action potential moves across the atrial muscle like ...
Dynamic Cardiology Station for Paramedic National Registry
... Defibrillator While CPR in progress ...
... Defibrillator While CPR in progress ...
Heart muscle engineering: An update on cardiac muscle
... Akt-kinase pathway [66,67]. An important task for cardiac tissue engineers in the future is certainly to identify more and ultimately all factors including optimal concentrations and time windows in which specific factors have to be present during culture. So far, growth factors are mostly applied b ...
... Akt-kinase pathway [66,67]. An important task for cardiac tissue engineers in the future is certainly to identify more and ultimately all factors including optimal concentrations and time windows in which specific factors have to be present during culture. So far, growth factors are mostly applied b ...
Double-Chambered Right Ventricle and Situs Inversus With
... from the body of the septal band (septomarginal trabeculation) and pass through the chamber of the right ventricle to the anterior free wall. DCRV is exceptionally rare as an isolated anomaly. Most commonly (in approximately 90% of affected individuals) it is associated with a membranous-type ventri ...
... from the body of the septal band (septomarginal trabeculation) and pass through the chamber of the right ventricle to the anterior free wall. DCRV is exceptionally rare as an isolated anomaly. Most commonly (in approximately 90% of affected individuals) it is associated with a membranous-type ventri ...
Introductory Program
... Blood flow is greatest early in systole and diastole. Approximately two-thirds of the blood ejected (stroke volume) leaves the ventricle in the first one-third of systole, and two-thirds of the blood filling the ventricle enters during the first one-third of diastole. This information is useful whe ...
... Blood flow is greatest early in systole and diastole. Approximately two-thirds of the blood ejected (stroke volume) leaves the ventricle in the first one-third of systole, and two-thirds of the blood filling the ventricle enters during the first one-third of diastole. This information is useful whe ...
Chapter 6
... prognosis in a number of different clinical conditions (2,9,10). Particularly in patients with coronary artery disease, LVEF is the strongest predictor of long-term survival (11-13). In patients with stable angina, the annual mortality rate exceeds 3% for those patients with LVEF <35% (10,14). In ad ...
... prognosis in a number of different clinical conditions (2,9,10). Particularly in patients with coronary artery disease, LVEF is the strongest predictor of long-term survival (11-13). In patients with stable angina, the annual mortality rate exceeds 3% for those patients with LVEF <35% (10,14). In ad ...
Intelligent Modeling To Predict Ejection Fraction From
... ventricles become less compliant and are routinely echocardiographically proven to have an EF from 55-85% with the help of good genetics and a healthy lifestyle. The EF is one of the most important predictors of prognosis; those with significantly reduced ejection fractions typically have poorer pro ...
... ventricles become less compliant and are routinely echocardiographically proven to have an EF from 55-85% with the help of good genetics and a healthy lifestyle. The EF is one of the most important predictors of prognosis; those with significantly reduced ejection fractions typically have poorer pro ...
HEART MURMURS
... The scenario is quite different, however, if the pediatrician detects a murmur that may not be normal. Abnormal murmurs usually indicate potentially serious heart problems, although they are usually not immediately life threatening. An abnormal murmur may be caused by a structural problem such as a ...
... The scenario is quite different, however, if the pediatrician detects a murmur that may not be normal. Abnormal murmurs usually indicate potentially serious heart problems, although they are usually not immediately life threatening. An abnormal murmur may be caused by a structural problem such as a ...
2009 HF Guidelines: Diagnosis and management of right
... hypertension while on optimal therapy may be considered for therapy with sildenafil for symptom improvement and exercise tolerance ...
... hypertension while on optimal therapy may be considered for therapy with sildenafil for symptom improvement and exercise tolerance ...
Syncope 1.CS.Name the type of syncope ,that is most frequently met
... E. Arrhythmic syncope with vital risk ...
... E. Arrhythmic syncope with vital risk ...
Temporal Trends in Hospitalisations for Heart Failure
... days, a relative increase of 3.2% over the 8-year period. Although not statically significant it did show a general trend (p=0.08). Interestingly, our study also showed that the LOS had minimal change over the 8 year period when analysed by age group. However trying to account for the lack of declin ...
... days, a relative increase of 3.2% over the 8-year period. Although not statically significant it did show a general trend (p=0.08). Interestingly, our study also showed that the LOS had minimal change over the 8 year period when analysed by age group. However trying to account for the lack of declin ...
Regular
... originating from the sinus node). The atrial rate is usually above 350 beats per minute Atrial activity is chaotic (resulting in an ...
... originating from the sinus node). The atrial rate is usually above 350 beats per minute Atrial activity is chaotic (resulting in an ...
BACK TO GAME
... 1 – Impulse travels along interventricular septum within AV bundle and bundle branches to Purkinje fibers. 2 – Impulse distributed and relayed throughout ventricular myocardium; ventricular contraction begins. 3 – 100-msec delay at AV node; atrial contraction begins. 4 – SA node activity and atrial ...
... 1 – Impulse travels along interventricular septum within AV bundle and bundle branches to Purkinje fibers. 2 – Impulse distributed and relayed throughout ventricular myocardium; ventricular contraction begins. 3 – 100-msec delay at AV node; atrial contraction begins. 4 – SA node activity and atrial ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.