B-Type Natriuretic Peptide
... bioactivity in circulation, e.g., hypertension (53, 54 ). Corin thus seems to be involved in the biosynthesis of natriuretic peptides, and one report even suggests that corin is active in the circulation (55 ). Of note, atrial posttranslational processing of proANP and proBNP is likely to differ fro ...
... bioactivity in circulation, e.g., hypertension (53, 54 ). Corin thus seems to be involved in the biosynthesis of natriuretic peptides, and one report even suggests that corin is active in the circulation (55 ). Of note, atrial posttranslational processing of proANP and proBNP is likely to differ fro ...
The Sequence of Normal Recovery of Excitability in the
... side of the interveiitricular septum had longer refractory periods than those of the right side. In each of these instances, the area normally activated earliest had the longer refractory period. A similar organization of recovery properties was suggested by the refractory periods measured in this s ...
... side of the interveiitricular septum had longer refractory periods than those of the right side. In each of these instances, the area normally activated earliest had the longer refractory period. A similar organization of recovery properties was suggested by the refractory periods measured in this s ...
47 an analysis of control of the ventricle of the mollusc mercenaria
... increased when external Ca2+ was raised from 0 to 9mmol l21. Both the amplitude and frequency of beats were maximal at a Ca2+ concentration around 9mmol l21. Concentrations of extracellular Ca2+ greater than 18mmol l21 inhibited beating and caused a slight membrane depolarization. The membrane becam ...
... increased when external Ca2+ was raised from 0 to 9mmol l21. Both the amplitude and frequency of beats were maximal at a Ca2+ concentration around 9mmol l21. Concentrations of extracellular Ca2+ greater than 18mmol l21 inhibited beating and caused a slight membrane depolarization. The membrane becam ...
ACC/AHA Practice Guidelines
... This document was approved by the American College of Cardiology Foundation Board of Trustees on May 7, 2004 and by the American Heart Association Science Advisory and Coordinating Committee on May 5, 2004. The ACC/AHA Task Force on Practice Guidelines makes every effort to avoid any actual or poten ...
... This document was approved by the American College of Cardiology Foundation Board of Trustees on May 7, 2004 and by the American Heart Association Science Advisory and Coordinating Committee on May 5, 2004. The ACC/AHA Task Force on Practice Guidelines makes every effort to avoid any actual or poten ...
Syncope - Brain 101
... Class I indication for pacing using dualchamber system wherever adequate atrial rhythm is available Ventricular pacing in atrial fibrillation with slow ventricular response ...
... Class I indication for pacing using dualchamber system wherever adequate atrial rhythm is available Ventricular pacing in atrial fibrillation with slow ventricular response ...
Relation of Cardiac Surface QRST Distributions to Ventricular
... bipolar stimulating electrodes used for delivering basic driving stimuli were attached to the right atrium and right ventricle near the pulmonary conus. Two additional bipolar electrodes were placed on the anterior right ventricle for delivering VFT test stimuli. The heart was paced at a cycle lengt ...
... bipolar stimulating electrodes used for delivering basic driving stimuli were attached to the right atrium and right ventricle near the pulmonary conus. Two additional bipolar electrodes were placed on the anterior right ventricle for delivering VFT test stimuli. The heart was paced at a cycle lengt ...
Single-Beat Estimation of the Slope of the End
... one needs at least two pressure-volume loops with fairly different end-systolic pressures in a constant inotropic state.9 The complexities of the method may decrease the clinical usefulness of ESPVR and Ees for assessing left ventricular contractility. Accordingly, this study proposes and assesses a ...
... one needs at least two pressure-volume loops with fairly different end-systolic pressures in a constant inotropic state.9 The complexities of the method may decrease the clinical usefulness of ESPVR and Ees for assessing left ventricular contractility. Accordingly, this study proposes and assesses a ...
Left Atrial Enlargement in Young High
... ventricular end-systole, in atrial maximal size. The LA area was measured in a 4-chamber view. LA volume (LAV) was calculated by the Simpson’s method and then indexed to the body surface area as a LA volume index (LAVI). During LA size assessment the LA appendage and pulmonary veins were excluded an ...
... ventricular end-systole, in atrial maximal size. The LA area was measured in a 4-chamber view. LA volume (LAV) was calculated by the Simpson’s method and then indexed to the body surface area as a LA volume index (LAVI). During LA size assessment the LA appendage and pulmonary veins were excluded an ...
Screening for undiagnosed atrial fibrillation in the community
... time point in unselected patients in the community. Thirty studies, representing 122 571 patients, were included and the overall prevalence of atrial fibrillation in the total population was 2.3% (95% CI 2.2–2.4). If only patients aged at least 65 years were considered, the prevalence was 4.4% (95% ...
... time point in unselected patients in the community. Thirty studies, representing 122 571 patients, were included and the overall prevalence of atrial fibrillation in the total population was 2.3% (95% CI 2.2–2.4). If only patients aged at least 65 years were considered, the prevalence was 4.4% (95% ...
When Cardiac Ablation Should Be First Line Therapy
... Sinus Tachycardia Note the classic S1Q3T3 seen with ...
... Sinus Tachycardia Note the classic S1Q3T3 seen with ...
Pulmonary Valve
... Need to maintain adequate preload for non-compliant RV, avoid hypovolemia Avoid tachycardia to improve preload to RV, time to empty May require inotropic/vasoactive support for short period of time following procedure (Both balloon and surgical intervention) Persistent cyanosis due to RV non ...
... Need to maintain adequate preload for non-compliant RV, avoid hypovolemia Avoid tachycardia to improve preload to RV, time to empty May require inotropic/vasoactive support for short period of time following procedure (Both balloon and surgical intervention) Persistent cyanosis due to RV non ...
A Direct Examination of Papillary Muscle Function in the Canine Left
... suggested that the wrinkled nature of the ventricular cavity allowed greater ventricular emptying, since the trabeculae carneae and papillary muscles by occupying a progressively greater volume of the cavity during systole, displaced a proportionally greater volume of blood into the systemic circuit ...
... suggested that the wrinkled nature of the ventricular cavity allowed greater ventricular emptying, since the trabeculae carneae and papillary muscles by occupying a progressively greater volume of the cavity during systole, displaced a proportionally greater volume of blood into the systemic circuit ...
Comparison of ThreeDimensional Speckle Tracking
... Limitation Section: However, some important limitations should be taken into consideration analyzing our results: (1) Left atrial appendage for calculation of LA volume and function was not included due to its variability in shape and lack of standard figures (3). (2) As mentioned previously, current ...
... Limitation Section: However, some important limitations should be taken into consideration analyzing our results: (1) Left atrial appendage for calculation of LA volume and function was not included due to its variability in shape and lack of standard figures (3). (2) As mentioned previously, current ...
Anterior and posterior left ventricular sarcomere lengths behave
... approximately four o’clock. If we were to rotate the left ventricle around its long axis, we would then have altered the differential offset of the gravitational field at the two sites. As seen in Fig. 2, such rotation did indeed affect that portion of the trajectories relating SL to volume during d ...
... approximately four o’clock. If we were to rotate the left ventricle around its long axis, we would then have altered the differential offset of the gravitational field at the two sites. As seen in Fig. 2, such rotation did indeed affect that portion of the trajectories relating SL to volume during d ...
(1-7)对腹主动脉缩窄大鼠心肌肥厚和纤维化的影响
... Twenty-four hours after the operation, an osmotic minipump with a pumping rate of 0.25 μl/h lasting for 28 days was implanted subcutaneously for drug delivery via a catheter in the jugular vein. The rats with aortic coarctation received Ang-(1-7) (25 μg·kg-1·h-1) or saline (0.25 μl/h) and the sham- ...
... Twenty-four hours after the operation, an osmotic minipump with a pumping rate of 0.25 μl/h lasting for 28 days was implanted subcutaneously for drug delivery via a catheter in the jugular vein. The rats with aortic coarctation received Ang-(1-7) (25 μg·kg-1·h-1) or saline (0.25 μl/h) and the sham- ...
Gallop Rhythm of the Heart
... cardiogram (B). The ventricular gallop (vG) occurs in early diastole. The presystolic atrial gallop (aG) follows the P wave hut precedes the QRS complex. The first andl second heart sounds are indicated by 1 and respectively. Each gallop sound (vG and aG) occurs simultaneously with a gallop bulge (G ...
... cardiogram (B). The ventricular gallop (vG) occurs in early diastole. The presystolic atrial gallop (aG) follows the P wave hut precedes the QRS complex. The first andl second heart sounds are indicated by 1 and respectively. Each gallop sound (vG and aG) occurs simultaneously with a gallop bulge (G ...
Parasympathetic control of the heart. I. An interventriculo
... Subsequent to multiple microinjections of diamidino yellow into the anterior apical surface of the left ventricle (Fig. 2), there was a statistically significant difference in the percentage of the total number of neurons that were retrogradely labeled within individual intracardiac ganglia [F(7,22) ...
... Subsequent to multiple microinjections of diamidino yellow into the anterior apical surface of the left ventricle (Fig. 2), there was a statistically significant difference in the percentage of the total number of neurons that were retrogradely labeled within individual intracardiac ganglia [F(7,22) ...
NIH Public Access - IUPUI ScholarWorks
... shortening of CaiTD kept ΔCaiTD50–APD50 small (11 ± 4 ms, Figure 7A). In contrast, responses to nifedipine varied when nifedipine was administered after ES developed (posttreatment group, n=5). Nifedipine suppressed VT/SVF in one heart that had a long period of VT prior to SVF recurrence (Figure 7B) ...
... shortening of CaiTD kept ΔCaiTD50–APD50 small (11 ± 4 ms, Figure 7A). In contrast, responses to nifedipine varied when nifedipine was administered after ES developed (posttreatment group, n=5). Nifedipine suppressed VT/SVF in one heart that had a long period of VT prior to SVF recurrence (Figure 7B) ...
Print - Circulation
... for optimal matching of regions before and after contraction, especially when analyzing regional function in the presence of significant local pathology. The reason for this (illustrated in Figure 3) was that the normal slice centroid, and hence the long axis, may move significantly during contracti ...
... for optimal matching of regions before and after contraction, especially when analyzing regional function in the presence of significant local pathology. The reason for this (illustrated in Figure 3) was that the normal slice centroid, and hence the long axis, may move significantly during contracti ...
Prior exercise improves survival, infarct healing, and left ventricular
... Prior exercise improves survival, infarct healing, and left ventricular function after myocardial infarction Monique C. de Waard and Dirk J. Duncker Experimental Cardiology, Dept. of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands Submitted 24 Se ...
... Prior exercise improves survival, infarct healing, and left ventricular function after myocardial infarction Monique C. de Waard and Dirk J. Duncker Experimental Cardiology, Dept. of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands Submitted 24 Se ...
A Modest Proposal - We are Overdue for an International Fontan
... Clinical perspective: 1. The impact of treatment strategies targeted toward those with important laboratory abnormalities in the pathological range may influence FHS to an unknown degree but should be an important component of future studies. 2. Strategies targeting FHS and its non-cardiac determina ...
... Clinical perspective: 1. The impact of treatment strategies targeted toward those with important laboratory abnormalities in the pathological range may influence FHS to an unknown degree but should be an important component of future studies. 2. Strategies targeting FHS and its non-cardiac determina ...
Prior exercise improves survival, infarct healing, and left ventricular
... Prior exercise improves survival, infarct healing, and left ventricular function after myocardial infarction Monique C. de Waard and Dirk J. Duncker Experimental Cardiology, Dept. of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands Submitted 24 Se ...
... Prior exercise improves survival, infarct healing, and left ventricular function after myocardial infarction Monique C. de Waard and Dirk J. Duncker Experimental Cardiology, Dept. of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands Submitted 24 Se ...
syncope evaluation and management
... • Guidelines recommend EKG in the evaluation of all patients with syncope. • Exception: young healthy patients with an obvious cause of syncope • Abnormal EKG in 90% of patient with cardiac syncope • Only 6% of patients with reflex mediated syncope have abnormal EKG. • Syncopal patient with negative ...
... • Guidelines recommend EKG in the evaluation of all patients with syncope. • Exception: young healthy patients with an obvious cause of syncope • Abnormal EKG in 90% of patient with cardiac syncope • Only 6% of patients with reflex mediated syncope have abnormal EKG. • Syncopal patient with negative ...
Functional mitral regurgitation in patients with heart failure and
... Mitral regurgitation is a commonly encountered valvular lesion in modern clinical practice [1]. Mitral regurgitation can be further classified into organic (or primary) and functional (or secondary). Organic mitral regurgitation refers to regurgitant lesions resulting from disorders of the mitral va ...
... Mitral regurgitation is a commonly encountered valvular lesion in modern clinical practice [1]. Mitral regurgitation can be further classified into organic (or primary) and functional (or secondary). Organic mitral regurgitation refers to regurgitant lesions resulting from disorders of the mitral va ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.