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stabilization of the congestive heart failure patient in the er
stabilization of the congestive heart failure patient in the er

... absence of taurine deficiency as cats with taurine deficiency often respond well, if they can be made to survive for the first 2-3 weeks. Cats with normal taurine concentrations often respond poorly to medical therapy and may only live for a short time (days to months). In addition to oxygen, thorac ...
Amiodarone role in ventricular arrhythmias in aortic Stenosis
Amiodarone role in ventricular arrhythmias in aortic Stenosis

... wall stress. As consequence of the hemodynamic abnormality, myocardial hypertrophy is thought to be a compensatory process that leads to normalization in wall stress. Structural remodeling of the main myocardial components (myocytes, collagen, and microvessels) is initially adaptive, but may have de ...
Quantitative study of infarcted myocardium in - Heart
Quantitative study of infarcted myocardium in - Heart

CT and MR Imaging of Cardiac Tumors
CT and MR Imaging of Cardiac Tumors

... or severe LV Dysfunction) It can also be found in the right side of the heart ...
Nandrolone- induced myocardial infarction in a professional soccer
Nandrolone- induced myocardial infarction in a professional soccer

... as AAS. Anabolism is the metabolic process that builds larger molecules from smaller ones. Anabolic steroids were first discovered in the early 1930s and have since been used for numerous medical purposes including stimulation of bone growth, appetite, puberty, and muscle growth. The most widespread ...
Acute Ventricular Rate Control in Atrial Fibrillation
Acute Ventricular Rate Control in Atrial Fibrillation

... arm had episodes of loss of ventricular rate control. The loss of rate control in the combination-treatment arm was significantly less than that in the diltiazemalone arm (14 vs 39 episodes; 0.5 ⫾ 1.0 vs 1.5 ⫾ 2.1 episodes per patient; p ⫽ 0.05). The loss of rate control among the patients with epis ...
Acute Ventricular Rate Control in Atrial Fibrillation
Acute Ventricular Rate Control in Atrial Fibrillation

... arm had episodes of loss of ventricular rate control. The loss of rate control in the combination-treatment arm was significantly less than that in the diltiazemalone arm (14 vs 39 episodes; 0.5 ⫾ 1.0 vs 1.5 ⫾ 2.1 episodes per patient; p ⫽ 0.05). The loss of rate control among the patients with epis ...
chapter 3 - ART
chapter 3 - ART

... smaller than A, and the E : A ratio increases during pregnancy toward 1, to be inversed after birth. Fetal cardiac blood flow patterns differ from those in the neonate and the adult. Flow in the fetus results from simultaneous ejection from both right and left ventricles into the systemic circulatio ...
cardiac arrhythmias and left ventricular hypertrophy in systemic
cardiac arrhythmias and left ventricular hypertrophy in systemic

... Increased QT dispersion has been associated with ventricular arrhythmia and sudden death in a variety of cardiac disorders.5,6 The most consistently observed abnormality is prolongation of the action potential duration and refractoriness which sets the stage for arrhythmias based on early or delayed ...
Maximal Exercise Tolerance in Chronic
Maximal Exercise Tolerance in Chronic

... Maximal exercise testing was performed in all patients who were in the postprandial state using either an incremental multistage treadmill protocol (Modified Naughton Protocol) with 2-min stages'3 or an electronic bicycle ergometer protocol (Wasserman Ramp protocol) starting at a workload of 10 W an ...
Disfungsi Diastolik Ventrikel Kiri pada Pasien Diabetes Melitus Tipe 2 :
Disfungsi Diastolik Ventrikel Kiri pada Pasien Diabetes Melitus Tipe 2 :

... Faculty of Medicine, University of Indonesia/Cipto-Mangunkusumo Hospital, Jakarta, since October 2003 until February 2004, were examined for echocardiography ( 2-D, M-mode, Doppler imaging ).Diastolic dysfunction was found in 58.1 % of chronic renal failure patients on hemodialysis. There was no sig ...
Labetalol acls
Labetalol acls

... Here are the Primary ACLS drugs broken down by ACLS Algorithm. Each is a link to its respective page which covers, in detail, all aspects of the medication and it use. The goal for the acute management of patients with stroke is to stabilize the patient and to complete initial evaluation and assessm ...
NOREPINEPHRINE INDUCED PULMONARY CONGESTION IN
NOREPINEPHRINE INDUCED PULMONARY CONGESTION IN

... ence of valvular incompetence produces a decrease in the gradient of this downslope which is used as a measure of regurgitant flow. Minor variations of this gradient have been observed between normal subjects with the same forward flow and central volume and place a limit on the accuracy of backflow ...
Novel Techniques for Characterizing Myocardial Structure and
Novel Techniques for Characterizing Myocardial Structure and

... 2D echocardiography. Its superiority to 2D echocardiographic imaging is largely due to the fact that no geometrical assumptions and no extrapolation of the endocardial border for the regions in between scanning planes are necessary. Assessment of regional ventricular function: The volume enclosed in ...
Document
Document

... .intracerebral pressure and sometimes in headache -3.The nitrates dilate vessels in the skin resulting in flushing )2( They relax bronchial and biliary tract smooth muscle with the latter action )3( .resulting in a reduction of biliary pressure Route of administration a. Nitroglycerin is usually giv ...
Relationships Between Right Ventricular Function, Body
Relationships Between Right Ventricular Function, Body

... the predictors of cachexia. The impact on survival was tested by using the Cox proportional hazards model. Results A total of 408 predominantly male subjects with chronic HF (median duration 6.3 years; interquartile range 2.4 to 12 years) were enrolled (Table 1). Optimal medical and device therapies ...
Prognostic impact of restored sinus rhythm in patients
Prognostic impact of restored sinus rhythm in patients

... circulation, or hepatic failure; renal dysfunction; dopamine use; and norepinephrine use. The logistic regression models were constructed to analyze the singificant predictors of NeOAF and NeOAF to AF in patients with sepsis. For all patients with NeOAF, these predictors included age, heart failure, ...
Valvular Heart Disease in Pregnancy
Valvular Heart Disease in Pregnancy

... increase in heart rate, which contributes to an increase in cardiac output. However, the placental circulation offers a decrease in systemic vascular resistance, which can be favorable for certain cardiac lesions.1,2 Hemodynamic changes during labor and delivery At the time of labor and delivery, th ...
Non-cardiac Surgery in the Adult Congenital Heart Patient
Non-cardiac Surgery in the Adult Congenital Heart Patient

... fenestration  is  made  between  the  right  atrium  and  the  conduit  to  decrease  the   likelihood  of  developing  a  pleural  effusion  by  serving  as  a  “pop-­‐off”  when  the   pulmonary  vascular  resistance  becomes  significant ...
Helium ventilation for treatment of post
Helium ventilation for treatment of post

... These results might open the door to a new treatment of brain injury following cardiac arrest. Helium might reduce the reperfusion injury, but our study was not designed to demonstrate this and subsequent studies on the potential therapeutic value of helium in organ protection following ischaemia re ...
Changes in left ventricular filling dynamics with treadmill exercise in
Changes in left ventricular filling dynamics with treadmill exercise in

... R. M. Peters, T. Silberstein In patients with resting left ventricular diastolic abnormalities, it is not known if their transmitral diastolic flow velocity patterns in response to exercise are different from the response seen in normal subjects. Treadmill stress echocardiography was performed on 31 ...
The Evaluation of Applied Anaesthetic Techniques
The Evaluation of Applied Anaesthetic Techniques

... valvular lesion rates were higher (75.7%). The relationship between existing cardiac disease and anaesthetic management was not significant (p=0.28). However, we determined that parturients with higher NYHA (New York Heart Association) classifications had higher general anaesthesia rates. (p=0.001). ...
Syncope and The Older Patient
Syncope and The Older Patient

... Association with young and healthy men from southeast asia who present with sudden cardiac death Brugada sign may be asymptomatic High risk of sudden cardiac death in those who have syncope or family history of sudden death (Indication for AICD based upon observational data) ...
Implantable Cardioverter Defibrillator (ICD)
Implantable Cardioverter Defibrillator (ICD)

... - history of syncope (n=23) - ventricular arrhythmias by the EPS (n=18) During 7.9± 3.6 years of follow-up, 2 patients with prior arrest received appropriate ICD shocks. None of the 30 patients without prior arrest had a sustained arrhythmia detected. ICD-related adverse effects occurred in 11 (33%) ...
Model 5391 - KentuckyOne Health
Model 5391 - KentuckyOne Health

... especially suited for stimulation of the heart in the following cases: • treatment of patients before an operation, whereby an implantable pacemaker is being inserted. • treatment of tachyarrhythmia. • treatment of special cases of acute myocardial infarction. • treatment of patients after heart sur ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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