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Implantable Cardioverter Defibrillator (ICD)
Implantable Cardioverter Defibrillator (ICD)

... - history of syncope (n=23) - ventricular arrhythmias by the EPS (n=18) During 7.9± 3.6 years of follow-up, 2 patients with prior arrest received appropriate ICD shocks. None of the 30 patients without prior arrest had a sustained arrhythmia detected. ICD-related adverse effects occurred in 11 (33%) ...
pdf Cardiac Device Patient Parent Brochure
pdf Cardiac Device Patient Parent Brochure

... resynchronization therapy (CRT) system relieves symptoms of heart rhythm disturbances. It does this by restoring normal heart rates. A normal heart rate provides your body with the proper amount of blood circulation. The pacemaker system is intended for patients who need rate-adaptive pacing or chro ...
Working Group Report - Besancon.cardio.com
Working Group Report - Besancon.cardio.com

... walking continuously if possible, and performance is quantified by distance walked. This test is less likely to discriminate between NYHA Class II and III than the measurement of peak VO2, but may be well suited for patients with moderate to severe heart failure in whom repeated testing is used for ...
What is cardiomyopathy?
What is cardiomyopathy?

Dispersion of Ventricular Depolarization-Repolarization
Dispersion of Ventricular Depolarization-Repolarization

... noninvasive predictor of recurrent arrhythmic events. However, these ECG markers have never been evaluated in patients who died suddenly with ARVC proven at autopsy. The present study was designed to investigate the value of clinical and ECG findings as well as QT-QRS dispersion in predicting the ri ...
Medical Policy Surgical Ventricular Restoration
Medical Policy Surgical Ventricular Restoration

... An example of a surgical ventricular restoration device for cardiac reconstruction and repair is the CorRestore™ Patch System from Samanetics Corporation. All surgical ventricular restoration is considered investigational regardless of the commercial name, the manufacturer, or FDA approval status. ...
Sudden Cardiac Death Thirty Years Ago and at Present. The Role of
Sudden Cardiac Death Thirty Years Ago and at Present. The Role of

... The predominant type of sinus node activation in animals assigned to Group S in the early phase of ischemia was neurogenic sympathetic activation (HR > IHR 125 beats/min). The same applies to sympathetic ventricular activation (VFT < 2.0 mV). Four of the eight dogs in the group developed spontaneous ...
Response of heart murmur intensity to isometric - Heart
Response of heart murmur intensity to isometric - Heart

... Thirty-six patients were studied, of whom 27 had proven cardiac lesions during previous diagnostic cardiac catheterization. The remaining 9 patients were felt to have unquestionable clinical evidence of specific valvular cardiac lesions. The lesions studied are listed in Table i, and were predominan ...
Long-Term Outcome of the Right Ventricular Outflow Tract Palliation
Long-Term Outcome of the Right Ventricular Outflow Tract Palliation

... serum hemoglobin level remained insignificant. Moreover, more than half of the children needed to intubation and oxygen support; however, this requirement did not lead to increased risk of mortality or life-threatening events. Reviewing the literature confirms our findings with respect to the outcom ...
Applied physiology: Understanding shock
Applied physiology: Understanding shock

... used represents the oxygen consumption. This concept can be applied to the whole body or to an individual organ. In health, whole-body oxygen delivery exceeds consumption by a factor of approximately 4, so it is evident that there is a ‘safety margin’ before a reduction in oxygen delivery will adver ...
Inhaled beta2-agonists and beta-blockers in patients with chronic
Inhaled beta2-agonists and beta-blockers in patients with chronic

Potential role of nutritional factors
Potential role of nutritional factors

... results suggest that PGE1, formed from dihomo-gammalinolenic acid (DGLA) that is the precursor of AA, has markedly beneficial effects of myocardial energetics and on cardiac function in patients with severe ischemic congestive cardiac failure. It is likely that PGI2 (prostacyclin), a product from AA ...
G-protein-coupled receptor kinase activity in human heart failure
G-protein-coupled receptor kinase activity in human heart failure

... It has been well recognised that serum PSA corelated with advancing patient age. Oesterling et al. (6) and Dalkin et al. (7) have recommended adjustment of the upper normal limit of serum PSA for advancing age. Tumor markers play an important role in the assessment of patients with some types of mal ...
Swallow syncope associated with complete atrioventricular
Swallow syncope associated with complete atrioventricular

... uncommon anomaly and usually drains into the right atrium through the coronary sinus which is dilated, measuring about 1 to 2 cm in diameter. In the rare setting of an absent right superior vena cava, this anomaly produces a truly giant coronary sinus because of the severely increased flow into the ...
break
break

... How to interpret genetic screening results in inherited cardiac diseases?(General talk) Risk stratification in hypertrophic cardiomyopathy: phenotype, genotype or both Dilated cardiomyopathy in children: diagnostic work-up and treatment The role of MRI in diagnosis and risk stratification in inherit ...
State of the Art Heart - 2012 - UK HealthCare
State of the Art Heart - 2012 - UK HealthCare

... The Linda and Jack Gill Heart Institute is at the forefront in the battle against heart disease and stroke in Kentucky and is nationally recognized as a leader in advancing the treatment and prevention of cardiovascular disease. Our mission is to improve heart health by providing clinical services b ...
Heart Failure and Transplantation
Heart Failure and Transplantation

... subspecialty. It does not replace the didactic dimensions of textbooks, other specific educational materials. It represents the basis for actual learning activities. A variety of formats are offered at the ISHLT Academy days and the ISHLT Annual Meetings. In addition, individual professional study m ...
Cardiac Mean Electrical Axis in Thoroughbreds—Standardization by
Cardiac Mean Electrical Axis in Thoroughbreds—Standardization by

... just to check for the presence and characterization of arrhythmias, not taking advantage of all the ECG potential for cardiovascular information [19,20]. The conclusion of the present study (MEA evaluation) is that Dubois is currently the most reliable method for the correct acquisition, interpretat ...
STICH M19.RV dysfunction.Kukulski-JTCVS
STICH M19.RV dysfunction.Kukulski-JTCVS

... Objective: Whether right ventricular dysfunction affects clinical outcome after coronary artery bypass grafting with or without surgical ventricular reconstruction is still unknown. The aim of the study was to assess the impact of right ventricular dysfunction on clinical outcome in patients with is ...
Mortality after partial left ventriculectomy in relation to
Mortality after partial left ventriculectomy in relation to

... 45.7% in three years. The mean survival time was 3.2 months (CI 95% = 0 to 7.4) for the patients with this contraindication and of eight months for patients who did not present with this contraindication. The accumulated survival probability for those with contraindications was 9.7 ± 2.5 months (CI ...
Questions and Answers About AEDs and Defibrillation
Questions and Answers About AEDs and Defibrillation

... defibrillated) and 95 percent specific (able to recommend not shocking when defibrillation is not indicated). Because of the wide variety of situations in which they will typically be used, AEDs are designed with multiple safeguards and warnings before any energy is released. AEDs are programmed to ...
Immediate recovery of the left atrial and left ventricular diastolic
Immediate recovery of the left atrial and left ventricular diastolic

... In long-standing severe AS, a time-related structural and histologic remodeling occurs both in the LV, LA, and thereafter in the LAA. LV diastolic dysfunction caused by AS is well established [18, 19] and is related with LA dilatation which is assumed an indicator of severity and chronicity of diast ...
Implication of right ventricular dysfunction on long
Implication of right ventricular dysfunction on long

... Objective: Whether right ventricular dysfunction affects clinical outcome after coronary artery bypass grafting with or without surgical ventricular reconstruction is still unknown. The aim of the study was to assess the impact of right ventricular dysfunction on clinical outcome in patients with is ...
Brain natriuretic peptide and optimal management of heart
Brain natriuretic peptide and optimal management of heart

... and cardiac transplantation. All these therapeutic interventions promote a return to a more normal ventricular size and shape. The correlation between BNP and the new heart failure classification remains to be clarified. BNP might not be a superior screening test to diagnose heart failure patient at ...
Strangulation of the heart following intrapericardial
Strangulation of the heart following intrapericardial

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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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