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Risk stratification after myocardial infarction: a
Risk stratification after myocardial infarction: a

... R–R component) is a more reliable predictor of arrhythmia risk in post-MI patients. Furthermore, peripheral finger pressures (FinapressTM ), used in most BRS methods, are not a precise representation of carotid pressures, especially with advancing age.16–18 In contrast to the conventional BRS measure ...
Anesthesia for Adult Patients With Congenital Heart Disease
Anesthesia for Adult Patients With Congenital Heart Disease

... not had any intervention because the magnitude of their hemodynamic disturbance is insufficient to warrant one, yet others with their native anatomy suffer from such extreme physiologic derangement that they are no longer candidates for reconstructive cardiac repair. “Corrective” interventions, even ...
EISENMENGER SYNDROME
EISENMENGER SYNDROME

... A composite score based on the strongest echocardiographic predictors of outcome, including 1 point for each of the following: – TAPSE<15 mm – Ratio of right ventricular effective systolic to diastolic duration> 1.5 – RA area > 25 cm2, ...
Use of Contrast Echocardiography for Evaluation of
Use of Contrast Echocardiography for Evaluation of

... related with the hemodynamic status observed at cardiac catheterization. This correlation demonstrated that using specific contrast echocardiographic patterns, the intracardiac pressure-flow relationships could be determined accurately. In this manner, conclusions concerning the right ventricular an ...
cardiac output in man by a direct fick method
cardiac output in man by a direct fick method

... FIG. 9.-Collected data of cardiac output plotted against heart rate in normal resting males in the supine posture. The few with higher outputs show faster heart rates. ...
Monitoring cardiac function in intensive care
Monitoring cardiac function in intensive care

... interrelated variables: heart rate, preload, contractility, and afterload.8 Quantification of these individual components of cardiac function in the clinical setting poses two major problems. First, the methods used require either invasive (usually ventricular) pressure and volume measurements, or h ...
A 90-year-old patient presenting with postoperative hypotension and
A 90-year-old patient presenting with postoperative hypotension and

... hypotension is common and can be due to variety of causes. Systolic anterior motion of the mitral valve leading to left ventricular outflow tract obstruction is a rare cause of postoperative hypotension and can occur without prior structural heart disease. A high index of suspicion can lead to early ...
The Artificial Pacemaker . . . . . . A Pure Success Story!?
The Artificial Pacemaker . . . . . . A Pure Success Story!?

... Some of the resulting devices are not only supporting our aging population – they are even saving hundreds of human lives a day. Pacemakers are undoubted one of the most successfull developments of medical embedded systems. Therefore, this document will give a brief overview of the history and funct ...
Aging and the Cardiovascular System
Aging and the Cardiovascular System

... In addition, in aging, the response of the cardiovascular system to adrenergic stimulation is decreased.25 During exercise, the function of an aged heart resembles that of a young adult who is under beta-blocker medication.26 Furthermore, in aging, the inotropic response to digitalis is decreased, a ...
Supraventricular Tachycardia in the Pediatric Trauma
Supraventricular Tachycardia in the Pediatric Trauma

... band of creatine phosphokinase did not with either test. A study evaluating cardiac contusions in adults revealed that cardiac troponin I is a helpful diagnostic indicator of cardiac injury, with increased levels of cardiac troponin I correlating with increased risk of arrhythmia.6 Children were not ...
Dizziness and Syncope
Dizziness and Syncope

Mutations affecting the formation and function of the cardiovascular
Mutations affecting the formation and function of the cardiovascular

... tubes, the inner endocardium and outer myocardium (Fig. 1A,B). cloche (clo) deletes the endocardial cells. In this mutant, the myocardial layer forms in the absence of the endocardial cells but is dysmorphic: the ventricle is reduced in size and the walls of the atrium are distended. The clo heart a ...
EEG - Wayne State University
EEG - Wayne State University

... i. Atrial escape: pause + P’ waves with varying morphology + normal QRS and inherent rate 60-80 ii. Jxn escape: pause + no P wave + normal QRS and inherent rate 40-60 1. Jxn beat MAY produce retrograde atrial depol, seen as inverted P’ wave after the pause iii. Ventricular escape: pause + no P wave ...
Braunwald`s Heart Disease Review and Assessment
Braunwald`s Heart Disease Review and Assessment

... Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured ...
Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2008)
Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2008)

... relative blocking potency: low moderate high A: activated state channel blocker, I: inactivated state channel blocker, : agonist ATP: adenosine triphosphate, LV: left ventricular, ECG: electrocardiogram ...
Cardiopulmonary Exercise Testing: A Review of Techniques and
Cardiopulmonary Exercise Testing: A Review of Techniques and

... Treadmill testing, nuclear cardiology stress studies and debutamine stress echocardiography have been used to ascertain perioperative risk in patients undergoing major noncardiac surgery [6]. However these studies focus on a single organ in contrast to the Cardiopulmonary Exercise Testing (CPET) whi ...
Document
Document

... use blue pens for the structures on the right side of the heart, purple for the capillaries of the lungs, and red for the structures on the left side of the heart. Have them start with the inferior and superior venae cavae and end with the aorta. Then have them then put away their cards and ask them ...
Right ventricular cardiac myxoma. Histopathology diagnosis in
Right ventricular cardiac myxoma. Histopathology diagnosis in

... In search for candidate cells or tissues as precursor cells of cardiac myxoma, in 1951 Prichard [27] described a kind of microscopic endocardial structure of the atrial septum, which was suggested to be related to cardiac myxomas. The confirm the existence of Prichard’s structures and to clarify the ...
Cardiac Assessment in the Operating Room (Part 1)
Cardiac Assessment in the Operating Room (Part 1)

... – Also can be seen by TEE or visualization ...
Current management of patients with ST elevation myocardial
Current management of patients with ST elevation myocardial

... Study15 and 17±13 min in the Vienna STEMI Registry.12 Door-to-balloon-time was 85 min in the BLITZ study,10 111 min in GRACE,9 108 min in NRMI-3,14 93 min in ESC survey,5 81±51 min in the Vienna STEMI Registry,12109 min in the AMIQUEBEC study.15 In TIMI 9 Registry, 20% of patients treated with TT me ...
Relationship of Number of Phases per Cardiac Cycle and Accuracy
Relationship of Number of Phases per Cardiac Cycle and Accuracy

... for a heart rate of 60 beats/min, ranged from 4.0 s (for the 8-phase acquisition) to 9.4 s (for the 20-phase acquisition), and correlated well with the number of phases (R2 =0.99, p <0.0001) (Fig. 1). For a heart rate of 60 beats/min, the various acquisitions would correspond to a temporal resolutio ...
Acute Responses to Intermittent and Continuous Exercise in Heart
Acute Responses to Intermittent and Continuous Exercise in Heart

... Supplementary Material (section B).9,14,16,22-24 MICE isocaloric session This exercise session was performed on the ergocycle (Ergoline 800S) at an intensity of 60% PPO and consistent with current exercise training recommendations in patients with HFREF.1 Exercise duration was 22 minutes and matched ...
Semigran and J. Matthew Toole O`Connell, Francis D. Pagani
Semigran and J. Matthew Toole O`Connell, Francis D. Pagani

... ACCF/AHA 2009 HF guidelines7 Consideration of an LVAD as permanent or destination therapy is reasonable in highly selected patients with refractory end-stage HF and an estimated 1-year mortality ⬎50% with medical therapy (Class II; Level of Evidence B) HFSA comprehensive HF practice guidelines8 Pati ...
Valvular Heart Disease/Myopathy/Aneurysm
Valvular Heart Disease/Myopathy/Aneurysm

... Percutaneous aortic valve replacement (AVR)- new treatment being investigated for select patients with severe symptomatic aortic stenosis… Research at Cleveland Clinic is evaluating a percutaneous technique for implanting a prosthetic valve inside diseased calcific aortic valve. The procedure is per ...
Haemodynamic response to dynamic exercise after heart-lung transplantation
Haemodynamic response to dynamic exercise after heart-lung transplantation

... to left ventricular myocardial stiffness and incoordinate contraction and relaxation [10, 12, 24]. Although the authors did not specifically assess diastolic function in this study, it is tempting to speculate that the altered haemodynamic response to exercise after HLT is also related to a combinat ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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