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DIABETES MELLITUS INCREASES PLASMA CARDIOTHROPHIN
DIABETES MELLITUS INCREASES PLASMA CARDIOTHROPHIN

... study cohort. We also excluded patients with a left ventricular ejection fraction lower than 50%. Our results are important because they suggest an increase in the serum levels of CT-1 in diabetic patients without systolic dysfunction. To date, many studies have revealed that hypertension and heart ...
4c HOW TO READ AN EKG
4c HOW TO READ AN EKG

... to the beginning of the Q wave or the beginning of the R wave if the Q wave is absent. The PR interval represents the time period encompassing atrial depolarization up to but not including the start of ventricular depolarization. The normal duration of the PR interval is between 3-5 mm or .12 - .20 ...
Cryoablation Lesion with Atrial Arrhythmia after Fontan Operation
Cryoablation Lesion with Atrial Arrhythmia after Fontan Operation

... (mainly K ion) responsible for repolarization. • Medications including amiodarone, bretylium, sotalol prolong the QT interval, useful in treating almost all types of supraventricular & ventricular arrhythmias, but bretylium generally limited to use in ischemic ventricular arrhythmia. • Side effects ...
Happy heart syndrome
Happy heart syndrome

... When eligibility for inclusion was uncertain, cases were reviewed by the core team at the leading centre to reach a consensus.18 The InterTAKRegistry consists of currently 1750 patients, of which 485 presented with an emotional event leading to a TTS episode. The remaining patients had a physical, a ...
Presentation of acute pulmonary oedema Definition
Presentation of acute pulmonary oedema Definition

...  The renin-angiotensin-aldosterone system (RAAS) increases salt and fluid retention, which initially increases preload, end diastolic volume (EDV), SV and therefore CO via the Frank-Starling mechanism, but over time leads to cardiac dilatation and a reduction in contractility and CO, together with ...
Print This Information
Print This Information

... What makes your heart rate speed up or slow down? Your brain and other parts of your body send signals to stimulate your heart to beat either at a faster or a slower rate. Although the way all of the chemical signals interact to affect your heart rate is complex, the net result is that these signals ...
A Case of a Right Atrial and Inferior Vena Caval Thrombus
A Case of a Right Atrial and Inferior Vena Caval Thrombus

... vena cava, and was treated through surgical excision. The following is a detailed report of the case accompanied by a review of previous studies. Case ...
Antiarrhythmic Therapy in Pregnancy
Antiarrhythmic Therapy in Pregnancy

Emergency department diagnosis of pulmonary hypertension in a
Emergency department diagnosis of pulmonary hypertension in a

... portal hypertension, certain toxins, human immunodeficiency virus, and other infectious causes [1]. Primary cardiac tumors, such as that responsible for our patient's PH, are extremely rare often presenting with symptoms that can mimic more common diseases that are regularly encountered in the emerg ...
Paroxysmal Supraventricular Tachycardia in Patients
Paroxysmal Supraventricular Tachycardia in Patients

... only one had electrocardiographic evidence of the WolffParkinson-White syndrome. In two, antegrade pre-excitation was only manifest during atrial pacing and was much more evident when the left atrium (via the coronary sinus) was paced.'2 14, 16 Of great interest was the absence of any evidence of an ...
The Relationship between Tpeak-end Interval
The Relationship between Tpeak-end Interval

... undergoing percutaneous coronary intervention for STelevation myocardial infarction, a longer pre-PCI (but not post- PCI) Tp-e predicted all-cause one-year mortality (12). In patients with left ventricular systolic dysfunction and ICD therapy, Tp-e predicted both appropriate ICD therapy for ventricu ...
Atraumatie Right Ventricular Aneurysm
Atraumatie Right Ventricular Aneurysm

... substantiated. There was no evidence of a cardiac aneurysm in the chest x-ray at that time. Because of the possibility of a collagen disease, the patient was treated empirically with steroids and discharged. He continued to be symptomatic. Infiltrates in the right lower lung field were apparent in t ...
Stroke Update
Stroke Update

... B) The most frequent adverse events after initial stroke are myocardial infarction (MI) and fatal cardiac events C) Strokes result in complete or partial dependence in up to 50% of patients D) Approximately 5% of patients suffer stroke within 48 hr after initial TIA ...
Brittany Woznicki, 2012. Dilated Cardiomyopathy.
Brittany Woznicki, 2012. Dilated Cardiomyopathy.

... Pathophysiology of the Heart (Terms and Definitions) • Two main parts to the cardiac cycle: • Diastolic • Systolic • In order to determine how hard the heart is working you must understand the two terms: • Preload: the volume of blood the heart pumps out • Afterload: the pressure required for the h ...
Structural Heart Defects and Stroke Structural Heart Defects and
Structural Heart Defects and Stroke Structural Heart Defects and

... • Lambl’s excrescences (filliform ...
Pre-hospital thrombolysis is associated with mortality reduction and
Pre-hospital thrombolysis is associated with mortality reduction and

... volume of blood remaining in the ventricle at the end of systole), ventricular fibrillation rates, and killip class on admission values. The secondary endpoint evaluated was if pre-hospital thrombolysis performed by non medical teams increases complication rates. The outcomes of interest were mortal ...
Detecting left ventricular impaired relaxation in cardiac MRI using
Detecting left ventricular impaired relaxation in cardiac MRI using

... Most of the existing left ventricle (LV) assessment algorithms using cine cardiac magnetic resonance (CMR) focus on the systolic function, and are often limited to the analysis of regional wall motion abnormalities or the estimation of the ejection fraction [1–3]. However, the diastolic function is ...
Prognostic Importance of Elevated Jugular Venous Pressure and S3
Prognostic Importance of Elevated Jugular Venous Pressure and S3

... trial has been described in detail previously.8,9 A total of 2569 patients with symptomatic congestive heart failure or a history of it and a left ventricular ejection fraction of 0.35 or less were randomly assigned to receive enalapril or placebo. Patients were enrolled from June 1986 to March 1989 ...
Assessment of the pressure–volume relationship of the single
Assessment of the pressure–volume relationship of the single

... sought to generate PV and PA loops from the single ventricle myocardial O2 consumption. There are four distinct phases that of a decapod crustacean. These loops would allow for a detailed include (1) isovolumic contraction as pressure is generated by assessment of stroke work and cardiac dynamics in ...
noţiuni de sănătate publică, epidemiologie şi informatică
noţiuni de sănătate publică, epidemiologie şi informatică

... Identification of viable myocardium in patients with left ventricular (LV) dysfunction secondary to coronary artery disease has an outstanding importance in establishing the optimal treatment strategy. In these patients, coronary revascularisation has been demonstrated to lead to an improvement of s ...
QT interval dispersion in obstructive sleep apnoea syndrome patients without hypertension
QT interval dispersion in obstructive sleep apnoea syndrome patients without hypertension

... hypertension. The aim of this study was to assess QTd in OSAS patients without hypertension. A total of 49 subjects without hypertension, diabetes mellitus, any cardiac or pulmonary diseases, or any hormonal, hepatic, renal or electrolyte disorders were referred for evaluation of OSAS. An overnight ...
Application of Lower Sternal Incision with On
Application of Lower Sternal Incision with On

... underwent incision surgery in the middle sternum with arresting heart. The diagnosis of all cases was confirmed by cardiac echocardiography, chest x-ray, and electrocardiography (ECG). The patients’ basic information is shown in Table 1. The patient was in supine position during the surgery. A small ...
Sudden cardiac death in chronic kidney disease: epidemiology and prevention
Sudden cardiac death in chronic kidney disease: epidemiology and prevention

... population.1,2 sudden cardiac death might be responsible for 60% of these cardiac deaths in patients undergoing dialysis.4 in those who also have diabetes mellitus, sudden cardiac death has been reported to be the most frequent cause cardiovascular death.4 even in the intermediate stages of chronic ...
TEE in Adult Congenital Heart Disease: Indication and Guideline
TEE in Adult Congenital Heart Disease: Indication and Guideline

... • Coarctation of aorta • ToF • Miscellaneous - Ebstein’s anomaly, corrected TGA, - Congenital coronary anomalies ...
Document
Document

... Cardiac output is the amount of blood pumped by the left ventricle each minute. It is adjusted moment-to-moment by the ANS, and by circulating hormones, changes in blood volume and in venous return. A healthy person can increase cardiac output by three-fold to five-fold. ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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