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EXPERIMENTS ON FROG CARDIOVASCULAR AND
EXPERIMENTS ON FROG CARDIOVASCULAR AND

... Determination of the excitation threshold, the refractory periods and the extrasystole. Action potentials are triggered when the membrane potential is depolarized up to the threshold of excitation. The minimal current amplitude necessary to reach the threshold can be determined using the ventricle w ...
Fate of Fresh Autologous Pericardium as Cardiovascular implant
Fate of Fresh Autologous Pericardium as Cardiovascular implant

... • Equalization of mean RA, PA wedge, RVED and LVED pressure help differentiate constrictive pericarditis to LV failure on cardiac catheterization ...
Digoxin Toxicity
Digoxin Toxicity

... majority of electrocardiographic changes documented for digoxin toxicity hospitalizations. Toxic digoxin levels may directly affect the sinoatrial node and cause sinus arrest or sinus exit block. Concurrent increased automaticity and vagal tone demonstrated by atrial tachycardia with atrioventricula ...
Document
Document

... Cardiac output is the amount of blood pumped by the left ventricle each minute. It is adjusted moment-to-moment by the ANS, and by circulating hormones, changes in blood volume and in venous return. A healthy person can increase cardiac output by three-fold to five-fold. ...
Acute Atrial Fibrillation as an Unusual Form of Cardiotoxicity
Acute Atrial Fibrillation as an Unusual Form of Cardiotoxicity

... In the majority of LT cases, neurologic and gastrointestinal symptoms predominate including nystagmus, ataxia, tremors, nausea, vomiting,and diarrhea.2 Cardiac toxicity is unusual and generally occurs in individuals with underlying heart disease. Classically, the cardiovascular manifestations of LT ...
Noninvasive reconstruction of cardiac electrical activity: update on
Noninvasive reconstruction of cardiac electrical activity: update on

... the feasibility of this approach [59, 60]. The wave-front formulation utilises different assumptions to model activation and repolarisation wave-fronts, by defining the wave-front (or more recently the complete endocardium and epicardium) as layer of current dipoles. [11, 22, 37, 38]. This approach ...
Ventricular Septal Defect and Ventricular Aneurysm following
Ventricular Septal Defect and Ventricular Aneurysm following

... also noted, together with diffuse cardiac impulse, suggesting left ventricular aneurysm. The enzymatic test showed SCOT 1040, LDH 1930. Rotating tourniquets were applied. On September 29, 1967, right heart catheterization hydrogen inhalation was done via right medial antecubital vein. The findings a ...
Valvular Heart Disease and Postoperative Considerations
Valvular Heart Disease and Postoperative Considerations

... terminated quickly should bradycardia or hypotension occur. If the patient is tachycardiac and hypotensive, phenylephrine is the pressor of choice because of its actions of increasing systemic vascular resistance and coronary perfusion pressure, while also causing a reflex bradycardia. However, phen ...
Interaction between systolic and diastolic time intervals in atrial
Interaction between systolic and diastolic time intervals in atrial

... ends with the onset of the succeeding ventricular systole. Nevertheless, we find considerable beat to beat variation in the exact time that it did so with respect to the onset of the QRS complex of the succeeding beat. When the RR interval was greater than 1000 ms the interval Q2 to mitral valve clo ...
Northwest Community EMS System VENTRICULAR
Northwest Community EMS System VENTRICULAR

... Wide QRS complexes: Impulse originates in an escape pacemaker site in the ventricles that takes longer than the normal time to conduct - so QRS will be wide (0.12 seconds or greater), distorted and ...
4.4. Mitral valve prosthesis vs. plasty and final result of the
4.4. Mitral valve prosthesis vs. plasty and final result of the

... Atrial fibrillation (AF) is one of the most common heart rhythm disturbances. The prevalence of this disorder in general population is 0.4 – 0.9%. AF incidence depends on the age of the patient: the incidence of AF in patients older than 60 years increases twofold every decade and in patients over 6 ...
SYMPOSIUM ON CONGESTIVE HEART FAILURE
SYMPOSIUM ON CONGESTIVE HEART FAILURE

... in cases of congestive heart failure. In general, right (aand indirectly determiiied left) ventricular diastolic pressure falls (reducing coligYestioii) while eardiae o-utput rises and the heart rate (inconstantly) slows. There is, however, no tinaiiiinity amoiig the various observers about the orde ...
cardiogenic shock
cardiogenic shock

... be used if patient has adequate blood pressure and adequate kidney function. Goal: Decrease preload and pulmonary congestion Mechanical-assist device placed in aorta that increases coronary artery and end organ perfusion and decreases afterload, which improves CO and decreases myocardial oxygen dema ...
S0735109714023572_mmc1
S0735109714023572_mmc1

... LV cardiomyocyte contractile dysfunction in PAH – data supplement Supplement - Materials and Method Cardiac MRI Retrospectively, 14 end-stage PH-patients were selected based on cardiac MRI availability. Cardiac MRI was measured within 3- 17 months before transplant or death (median, 10 months). For ...
annales 1-2_2010 bez Iwanickiego.indd
annales 1-2_2010 bez Iwanickiego.indd

... Fifty patients out of the 176-patient group who suffered from symptoms suggesting recurrent ischemia (history of effort angina symptoms, presenting positive exercise test, MACE) were enrolled during the period from May 2006 to September 2006 and referred to MSCT. Six patients were not examined because ...
Management of Chronic Heart Failure
Management of Chronic Heart Failure

... in patients with recent myocardial infarction and left ventricular systolic dysfunction. This combination does not confer additional benefits and can contribute to higher risk of adverse events such as hypotension, hyperkalaemia and reduced renal function.17 (Class III, Level B) ...
3. ECG ANALYSIS 3.1. Heartbeat
3. ECG ANALYSIS 3.1. Heartbeat

... The cause of respiratory arrhythmia is a tone fluctuation of vagus nerve nuclei (the decrease in tone during inspiration and the increase in tone during expiration). These nuclei are located close to a respiratory center in brainstem. Respiratory arrhythmia probably positively influences a gas excha ...
Determinants of Hemodynamic Compromise
Determinants of Hemodynamic Compromise

... included only patients with predominant severe RV infarction, caution must be used in extrapolating these results to patients with less severe RV infarction or with associated severe LV infarction. Results ...
Effect of Respiratory Therapy on the Prognosis of Chronic Heart
Effect of Respiratory Therapy on the Prognosis of Chronic Heart

... Background:  Sleep-disordered breathing (SDB) has been reported to influence mortality and occurrence of ventricular tachyarrhythmia in patients with chronic heart failure (CHF). It remains to be elucidated, however, whether respiratory therapy (RT) can affect the occurrence of fatal ventricular tac ...
Clinical and research issues regarding chronic advanced coronary
Clinical and research issues regarding chronic advanced coronary

... The following report is based on a working group meeting about advanced coronary artery disease for patients with refractory ischemia who cannot receive revascularization. The aims were to review currently available treatment strategies, define unmet clinical needs, explore clinical trial design iss ...
We Got the Beat Lesson Plan PDF
We Got the Beat Lesson Plan PDF

... (Slide 6) Show pictures of valves. Demonstrate how a valve works using a beach ball. (Slide 7) Visit the Science Museum of Minnesota’s website: “Habits of the Heart.” http://www.smm.org/heart/heart/pumping.htm This website shows an animation of how the blood flows through the heart (“Your Heart Valv ...
Thallium-201 myocardial SPECT in a patient with mirror
Thallium-201 myocardial SPECT in a patient with mirror

... Fig. 1 12 lead ECG which was obtained on right hemithorax. ...
New-onset atrial fibrillation as first clinical manifestation
New-onset atrial fibrillation as first clinical manifestation

... hypertrophy (141 patients). Many patients (448 patients) had other reasons to be excluded (AADs, cardioversions, psychotropic drugs, alcohol intoxication, thyroid dysfunction, etc.). No patient had prior ECG abnormalities consistent with Brugada ECG pattern and all of them had a normal ejection frac ...
Cardiac and Skeletal Muscle Insulin Resistance in
Cardiac and Skeletal Muscle Insulin Resistance in

... view of 10.5 cm, thus allowing the whole heart to be imaged. The spatial resolution was of 8.4 mm full width at half maximum (FWHM) for the emission, and 7.7 mm FWHM for the transmission data at the center of the field of view, with a slice thickness of 6.6 mm FWHM (17). Subjects lay supine on the s ...
Joseph Winaver, Aaron Hoffman and Zaid Abassi Tony
Joseph Winaver, Aaron Hoffman and Zaid Abassi Tony

... Hochberg, Joseph Winaver, Aaron Hoffman, and Zaid Abassi. Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure. Am J Physiol Heart Circ Physiol 289: H1351–H1358, 2005. First published May 13, 2005; doi:10.11 ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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