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Septal Occluder and Delivery System
Septal Occluder and Delivery System

... Patients indicated for ASD closure have echocardiographic evidence of ostium secundum atrial septal defect and clinical evidence of right ventricular volume overload (such as, 1.5:1 degree of left-to-right shunt or RV enlargement). Contraindications The AMPLATZER Septal Occluder is contraindicated f ...
Avian Medicine: Princilpes and Application
Avian Medicine: Princilpes and Application

... metabolic diseases that alter electrolyte balance. When evaluating cardiac enlargement it is best to compare the electrocardiographic findings with those of cardiac imaging techniques. The electrocardiogram may be of help in evaluating and diagnosing some of the diseases that cause vague signs of we ...
Left Atrial Ejection Force (LAEF)
Left Atrial Ejection Force (LAEF)

... It is difficult to evaluate the left atrial systolic function noninvasively. Previously, many techniques were used; posterior aortic echocardiogram to calculate left atrial volume change [7], the left atrial pressure-dimension relation [5], systolic time intervals [8]. Recently, Manning et al. have ...
Outpatient Oral Anticoagulant protocols
Outpatient Oral Anticoagulant protocols

... There is no need to monitor the INR in patients who are at home for the 5 days before surgery. The last dose of warfarin should be taken on the evening of day -6. LMWH is started on the morning of day -3 and is continued until day -1 (i.e. 24 hours before surgery). If the surgery poses a high risk o ...
Thrombolysis in the Era of Intervention
Thrombolysis in the Era of Intervention

... anti-platelets and anti-thrombotics, a routine PCI after 3 hours and before 24 hours is an attractive option.5 In CARESS trial,37 a more conservative strategy (i.e. angiogram only in cases of failed thrombolysis) was associated with a worse clinical outcome than the strategy of angiogram and interve ...
Fig. 1 - JACC: Cardiovascular Imaging
Fig. 1 - JACC: Cardiovascular Imaging

... not administered on post-CTA follow-up. The HeartNavigator system (Philips Healthcare, Best, the Netherlands) was the prototype proprietary software used for CTA-fluoroscopy fusion imaging. Pre-procedural CTA slices during enddiastole were 3D volume-rendered and automatically segmented to identify th ...
VALVULER HEART DISEASE
VALVULER HEART DISEASE

... In the normal heart, left ventricular (LV) contraction during systole forces blood exclusively through the aortic valve into the aorta; the closed mitral valve prevents regurgitation into the left atrium (LA). In mitral regurgitation (MR), a portion of the LV output is forced retrograde into the LA, ...
Management of Atrial Fibrillation
Management of Atrial Fibrillation

... be dimly aware of “something wrong” while another may experience profound discomfort. Occasionally chest pain may be the only presentation. The AF may also be asymptomatic and as much as 25% of patients may have no symptoms.7 Such asymptomatic episodes, however, can still result in adverse atrial re ...
hyper.ahajournals.org - Coordinating Center for Clinical Trials
hyper.ahajournals.org - Coordinating Center for Clinical Trials

... managed care organization, located in the southeastern United States, which offers healthcare benefits to nearly 200 000 persons enrolled in commercial or Medicare risk plans. The mean age of all of the patients taking antihypertensive medications in this organization was 63 years, and 55% were wome ...
Noninvasive Cardiac Imaging - American Academy of Family
Noninvasive Cardiac Imaging - American Academy of Family

... testing and more intensive treatment, whereas those at low risk of cardiac events can be treated with medical therapy and risk factor modification and avoid further testing.2-10,13,14 Figure 17 is an algorithm showing the diagnosis and risk stratification of patients with sus­ pected CAD; it is base ...
Understanding ecgs
Understanding ecgs

... – represents the greater part of ventricular repolarization • T wave – ventricular repolarization – same axis as QRS complex • U wave – uncertain ? negative afterpotential – More obvious when QTc is short ...
Download Pdf Article
Download Pdf Article

... is a synthetic sulfhydryl (thiol) compound that is usually co-administrated ifosfamide in order to reduce its harmfull effect in bladder and kidney. However, synovial sarcoma represents a suitable aspirant for molecular targeting and a phase I study usig STT/SST derived junction peptide vaccine has ...
The Anatomic Basis for High-Frequency Components in
The Anatomic Basis for High-Frequency Components in

... Except for Reynolds and co-workers14 in a recent study of patients with primary myocardial disease, most of the emphasis previously has been placed on a relationship between coronary artery disease and the appearance of notches and slurs of frequencies higher than that of the basic QRS complex.' 15 ...
Diabetic cardiomyopathy: mechanisms, diagnosis
Diabetic cardiomyopathy: mechanisms, diagnosis

... Brutsaert et al. [39] is that diastole is the time period where the myocardium is no longer generating force and subsequently returns to an unstressed length and force. Diastolic dysfunction occurs when there is prolongation and slowing of this process. Diastolic function can be assessed using cardi ...
Application of first-pass contrast bolus tracking sequence for the
Application of first-pass contrast bolus tracking sequence for the

... for the evaluation of congenital heart disease. However, this technique has limitations regarding the visualization of the pulmonary and great vessels and their connection sites (1). Catheter angiography is the gold standard imaging method for the evaluation of congenital vascular disorders, but it ...
The Potential Impact of Primary Percutaneous
The Potential Impact of Primary Percutaneous

... Background: Recent data suggest that the risk of acquired ventricular septal defect (VSD), a complication of acute myocardial infarction (AMI), could be reduced using thrombolytic therapy. There are, however, still no available data regarding the potential impact of primary percutaneous coronary int ...
The Potential Impact of Primary Percutaneous Coronary Intervention
The Potential Impact of Primary Percutaneous Coronary Intervention

... Background: Recent data suggest that the risk of acquired ventricular septal defect (VSD), a complication of acute myocardial infarction (AMI), could be reduced using thrombolytic therapy. There are, however, still no available data regarding the potential impact of primary percutaneous coronary int ...
Beneficial Effects of Physical Training and Methodology of Exercise
Beneficial Effects of Physical Training and Methodology of Exercise

Advanced (Stage D) Heart Failure - Heart Failure Society of America
Advanced (Stage D) Heart Failure - Heart Failure Society of America

... advanced progression of the heart failure syndrome characterized by structural abnormalities of the heart and severe resting symptoms despite optimal medical, surgical, and device therapy. The terms ‘‘stage D’’ and ‘‘advanced’’ are used interchangeably in the present document. Although a discussion ...
Full Text
Full Text

... At baseline, FRs were higher in patients with CHF than in control subjects (p ⬍ 0.01), TBARS were greater (p ⬍ 0.005), neutrophil O2⫺-generating capacity was enhanced (p ⬍ 0.005) and FMD was lower (p ⬍ 0.0001). Compared with placebo, short-term vitamin C therapy reduced FR levels (p ⬍ 0.05), tended ...
Conduction System in Man
Conduction System in Man

... lacked a continuous connective tissue sheath to delimit them from adjacent muscle. In fact, this sheath is so well developed in the ungulates, that it has been studied extensively by the injection of various dyes.5' 8, 37-41 However, with higher magnification the larger Purkinje fibers in man were r ...
Aging-related Changes in Cardiac Extracellular Matrix: Implications
Aging-related Changes in Cardiac Extracellular Matrix: Implications

... evaluated in the different age groups in randomized clinical trials ...
Left ventricular wall mechanics in hypertension
Left ventricular wall mechanics in hypertension

... the extent of left ventricular hypertrophy and left ventricular systolic performance in hypertensive patients. Left ventricular cavity measurements and wall thickness at the end diastole and end systole and shortening fraction were obtained with the precision by M - mode echocardiography. Fractional ...
Is Cardiac Magnetic Resonance Imaging Underutilized in the
Is Cardiac Magnetic Resonance Imaging Underutilized in the

... stiffness.6,7 This technique may provide a means to detect pulmonary vascular remodeling at an earlier stage of development, and may also ultimately be considered a target for PH-specific therapies. One potential role of CMR is detection in those patients who are “at risk” (ie, scleroderma patients) ...
Cardiology - New England EMS Institute
Cardiology - New England EMS Institute

... Dysrhythmias are the most common complication within the first few hours of chest pain ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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