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Stable angina pectoris
Stable angina pectoris

... Risk factors and prevention of atherosclerosis CHD is due to the imbalance between myocardial oxygen supply and demand Two large groups of CHD: chronic(stable angina pectoris) and ACS ACS composed of UAP/NSTEMI and STEMI, resulting from the plaque rupture or erosion, with differing degree of thr ...
The european infarction study experience
The european infarction study experience

... with slow release oxprenolol and 378 with placebo. In the oxprenolol group, 22 patients (6.1 %) died during the 1 year follow-up period as compared with 17 patients (4.5%) in the placebo group. Because these patients were recruited on the basis of willingness of the hospital to participate in this p ...
The Heart of the Matter: Cardiac Imaging of Sarcoidosis
The Heart of the Matter: Cardiac Imaging of Sarcoidosis

... 5. Greulich S, Deluigi CC, Gloekler S, et al. CMR imaging predicts death and other adverse events in suspected cardiac sarcoidosis. JACC Cardiovasc Imaging. 2013;6:501–511. 6. Blankstein R, Osborne M, Naya M, et al. Cardiac positron emission tomography enhances prognostic assessments of patients wit ...
EUROPACE P 500 I P 501 P 502
EUROPACE P 500 I P 501 P 502

... Background: For curative treatment of atria1 fibrillation (AF) the Maze-III procedure is considered a gold standard for restoration of sinus rhythm (SR) and atrial contraction. It is unknown whether the different type of operation has similar efficacy in patients with lone AF, as compared to AF asso ...
4.2.3.A EKGF
4.2.3.A EKGF

... messages. Electrical energy is what directs and choreographs the rhythmic beating of your heart. Each beat is initiated by an electrical signal. This electrical activity can be monitored and recorded in the form of a graph. The graph made in this process is called an electrocardiogram and is abbrevi ...
4.2.3.A EKGF
4.2.3.A EKGF

... messages. Electrical energy is what directs and choreographs the rhythmic beating of your heart. Each beat is initiated by an electrical signal. This electrical activity can be monitored and recorded in the form of a graph. The graph made in this process is called an electrocardiogram and is abbrevi ...
Acute Myocardial Infarction Complicated With Ventricular
Acute Myocardial Infarction Complicated With Ventricular

... non-invasive way of reducing the reperfusion injury. In 2002 a hypothesis was tested in studies on dogs that multiple repeated episodes of ischemia, produced in the beginning of reperfusion, would attenuate the reperfusion injury. This technique, called post-conditioning, was first used in patients ...
Long-Term Effects of Benidipine Hydrochloride on Severe Left
Long-Term Effects of Benidipine Hydrochloride on Severe Left

... rate(Table 1). Percentage changes of the LVMI and free TIMP-1 to MMP-1 ratio were significantly larger in patients with severe LVH(−27% and −54%)than in patients with mild LVH(−12% and −25%)and no LVH(−4% and −11%), respectively(p < 0.05 ; Tables 2, 3). Changes of the systolic blood pressure, but no ...
Delayed Presentation of Ventricular Septal Rupture – A Case Report Case Reports
Delayed Presentation of Ventricular Septal Rupture – A Case Report Case Reports

... ventricular septal rupture, as compared with 18 percent of those without ventricular septal rupture.6 Collaterals are less often evident in patients with ventricular septal rupture,2, 11, 18 supporting the hypothesis that collateral circulation reduces the risk of rupture of the cardiac free wall as ...
Ct Of The Heart
Ct Of The Heart

... heart and coronary arteries - basic ct anatomy of the heart and coronary arteries skip navigation sign in search loading coronary circulation of the heart duration 15 29, cardiac ct scans beacon hospital - minutes a 64 slice ct scan takes an image of the heart and arteries so detailed that followin ...
The emerging role of cardiovascular magnetic resonance imaging
The emerging role of cardiovascular magnetic resonance imaging

... Neither the age of onset nor the severity of cardiomyopathy is correlated with the type of mutation (26). It was recently documented that in DMD with preserved ejection fraction, the addition of eplerenone to background angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers att ...
Sequence timing optimization in multi-slice diffusion tensor
Sequence timing optimization in multi-slice diffusion tensor

... peak circumferential strain, which is considered 100% systole. In Figure 3 normalized myocardial diffusion gradient’s center (three orthogonal directions). The SNR as a function of the trigger delay normalized to end-systole is plotted for different heart rates. myocardial rotation is plotted in red ...
view a sample chapter
view a sample chapter

... these are silent periods. When you do detect an extra heart sound, listen carefully to note its timing and characteristics. ...
Chest X-ray
Chest X-ray

... • It is composed of fibrous tissue and although it will permit moderate changes in cardiac size, it cannot stretch rapidly enough to accommodate rapid dilation of the heart or accumulation of fluid without increasing intrapericardial (and, therefore, intracardiac) pressure. • The pericardium is ofte ...
Automated Heart Wall Motion Abnormality Detection From
Automated Heart Wall Motion Abnormality Detection From

... Coronary Heart Disease can be diagnosed by measuring and scoring regional motion of the heart wall in ultrasound images of the left ventricle (LV) of the heart. We describe a completely automated and robust technique that detects diseased hearts based on detection and automatic tracking of the endoc ...
Hypertrophic Cardiomyopathy in Children, Teenagers and Young
Hypertrophic Cardiomyopathy in Children, Teenagers and Young

1 Sudden cardiac death in young athletes Causes, athlete`s heart
1 Sudden cardiac death in young athletes Causes, athlete`s heart

... are no longer required for the diagnosis. Unfortunately, most athletes with hypertrophic cardiomyopathy remain asymptomatic until the time of death and are difficult to identify on the basis of history or physical examination. In one study (2), only 21% of athletes who died from this condition had s ...
Slide 1
Slide 1

... of the dropsy. I was told that it had long been kept a secret by an old woman of Shropshire, who had sometimes made cures after the more regular practitioners had failed… The medicine was composed of some twenty or more herbs; but it was not very difficult for one conversant with these subjects to p ...
Effect of Surgery for Atrial Fibrillation Associated With Mitral Valve
Effect of Surgery for Atrial Fibrillation Associated With Mitral Valve

... ADULT CARDIAC Fig 1. Actuarial survival curves for sinus and AF rhythm. (AF ⫽ atrial afibrillation; — ⫽ sinus; · · · ⫽ AF.) ...
The Cardiovascular System: The Heart Heart`s Place in the
The Cardiovascular System: The Heart Heart`s Place in the

... The heart rate is established by the SA node, as modified by autonomic activity, hormones, ions, etc. From there, the stimulus is conducted through the atrium to the AV node, the AV bundle, the bundle branches, and Purkinje fibers to the ventricular myocardium. The ECG shows the electrical events as ...
Increased plasma levels of adrenomedullin in patients with
Increased plasma levels of adrenomedullin in patients with

... failure were enrolled in the study (45 men, 19 women; range 28 to 86 years old, mean [+SD] 62 + 13) (Table 1) and classified into four groups according to cardiac symptoms by New York Heart Association functional class: class I = 15 patients (12 men, 3 women) mean age 58 _+ 11 years; class//= 25 pat ...
A Surgical Case of Combined Valvular Disease Complicated by
A Surgical Case of Combined Valvular Disease Complicated by

... belonging to Sherman’s type 3, is very rare,3) and this condition accounts for only 1% of PLSVC cases, 0.09% of autopsied cases of congenital heart disease, and 0.07% of intravenous pacemaker implantation cases.4-6) The hemodynamics of patients with PLSVC connected to the right atrium is the same as ...
ijst_160401
ijst_160401

... patient-adaptive cardiac profiling system, where a wavelet-based beat-detection mechanism first extracts fiducial ECG points following which a new local ECG beat classifier profiles patients normal cardiac behavior. Beat detection is a hybrid of Pan and Tompkins algorithm and wavelet analysis approa ...
ACC/AHA/NASPE Practice Guidelines
ACC/AHA/NASPE Practice Guidelines

... second-degree AV block” as a class I indication. This recommendation is based on several observational studies and is supported by a wealth of clinical experience. The narrative portion of this section also emphasizes that the site of origin of the escape rhythm in cases of advanced AV block is as i ...
BASIC ECG INTERPRETATION
BASIC ECG INTERPRETATION

... in the crowd at a football game.  Pacemaker cells can spontaneously depolarize as a result of spontaneous intracellular mechanisms.  All other muscle cells only depolarize as the result an external mechanism ( motor neuron stimulation) ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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