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MANAGEMENT OF PATIENTS WITH VALVULAR HEART DISEASE
MANAGEMENT OF PATIENTS WITH VALVULAR HEART DISEASE

... pulmonary edema & when contemplating future pregnancy. BMV can be performed safely in pregnancy after 20th week with radiation protection shield. Mitral regurgitation grade 2 or less, unicommissural calcium and LAA thrombus5 are not contraindication for BMV. In some patients MR may reduce after succ ...
BASIC ECG INTERPRETATION
BASIC ECG INTERPRETATION

... in the crowd at a football game.  Pacemaker cells can spontaneously depolarize as a result of spontaneous intracellular mechanisms.  All other muscle cells only depolarize as the result an external mechanism ( motor neuron stimulation) ...
Next Generation INCEPTA ICD and CRT
Next Generation INCEPTA ICD and CRT

... Considerable technical developments in this medical device therapy have been made over the last decade. In the past decades, heart disease has become the number one killer in the US1. Sudden Cardiac Death (SCD) accounts for almost half of all coronary heart disease deaths and affects 450,000 people ...
Prognostic Importance of ST-T Changes in ECG in Acute
Prognostic Importance of ST-T Changes in ECG in Acute

... most common changes.1 In a study of Lindgren et al20 transient ST-T changes were found in 54% of patients with ischemic stroke with no primary heart disease.In our study, as we included stroke patients with only ST-T changes in ECG, so we could not compare the frequency of various ECG changes in str ...
response and systolic wall stress in patients with
response and systolic wall stress in patients with

... 103 dyne/cm2; p < .005). At peak exercise there I or group 11(89 + 20 vs 70 + 18 and 69 ± 17 were no differences among groups in systolic blood pressure. However, end-systolic volume increased from 65 28 to 77 + 36 mI/m2 in group 111 and fell from 50 21 to 28 + 18 ml/i2 in group I during exercise. T ...
Predicting the Likelihood of Heart Failure with a Multi Level Risk
Predicting the Likelihood of Heart Failure with a Multi Level Risk

... multi output classes; and d) evaluate the proposed method by comparison with the results obtained from previous studies. II. STUDY CONTRIBUTION This study holds two principal contributions, which have previously been reported. The first contribution is to improve the early prediction of heart failur ...
Costs of atrial fibrillation in five European countries: results from the
Costs of atrial fibrillation in five European countries: results from the

... The manner in which quantities of resource use were determined depended on the answer options given in the enrolment case report form. A quantity of one resource unit was assumed to be incurred by a patient during the enrolment admission for any given diagnostic procedure [ECG, transthoracic echocar ...
Myocardial scar burden predicts survival benefit with
Myocardial scar burden predicts survival benefit with

... INTRODUCTION Implantable cardioverter defibrillators (ICDs) have been shown to reduce mortality in patients with ischaemic cardiomyopathy (ICM) and significant LV systolic dysfunction (LVD).1–3 Currently, echocardiographically-assessed LVEF and New York Heart Association class are the only established ...
Frog Heart Physiology
Frog Heart Physiology

... terminals. This neurotransmitter binds with muscarinic receptors and initiates many effects, including a cascade that increases the number of K+ channels in the open position; thus keeping the membrane near the equilibrium potential for K+ and making depolarization more difficult. The sympathetic ca ...
The Cardiovascular System: The Heart
The Cardiovascular System: The Heart

... atrium and ventricle with the pulmonary circuit and left atrium and ventricle with the systemic circuit. The left ventricle’s greater workload makes it more massive than the right, but the two pump equal amounts of blood. AV valves prevent backflow from the ventricles into the atria, and semilunar v ...
Rate Control vs Rhythm Control in Patients With
Rate Control vs Rhythm Control in Patients With

... length of hospital stay, 12.3 ⫾ 4.2 days). There were 211 hospitalizations in the group in which sinus rhythm restoration was attempted (mean length of hospital stay, 2.5 ⫾ 1.1 days). Excluding 104 hospitalizations required by protocol for cardioversion, there were 1.03 hospitalizations per person i ...
Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light
Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light

... failure with cardiomyocyte atrophy. We hypothesized that compensation after ablation of cMLCK is dependent on developmental staging and perinatal-onset of cMLCK ablation will result in more evident heart failure than germline ablation, but less profound when compared to adult-onset ablation. Methods ...
Image Quality Recovery in Cardiac CT Angiography
Image Quality Recovery in Cardiac CT Angiography

... the lung parenchyma, which is best seen using the lung window setting. Some pericardial motion blurring is common. Diaphragmatic motion, however, can cause generalized motion of the lungs and heart that results in blurring of the mid and peripheral lung tissue and displacement artifacts in the heart ...
PATHOPHYSIOLOGY OF CONGENITAL HEART DISEASE
PATHOPHYSIOLOGY OF CONGENITAL HEART DISEASE

... increases-RV enlargement. If PDA is large Eissenmenger syndrome can develop  Clinical features: depend on size & direction of flow, slow growth  Diagnosis: bounding pulse, continous murmur, loud S2 ...
Figure 12-9(b) - Cloudfront.net
Figure 12-9(b) - Cloudfront.net

... atrium and ventricle with the pulmonary circuit and left atrium and ventricle with the systemic circuit. The left ventricle’s greater workload makes it more massive than the right, but the two pump equal amounts of blood. AV valves prevent backflow from the ventricles into the atria, and semilunar v ...
Cardiac magnetic resonance imaging in pulmonary arterial
Cardiac magnetic resonance imaging in pulmonary arterial

... thromboembolic pulmonary hypertension (CTEPH). However, although computed tomography can be used to evaluate parameters such as cardiac function and myocardial perfusion, which are relevant to PAH, its use as a monitoring tool is limited by its relatively high radiation exposure. As noninvasive tech ...
Caring For Patients With Cardiomyopathy
Caring For Patients With Cardiomyopathy

...  In ...
Continuous Positive Airway Pressure for Central Sleep Apnea and
Continuous Positive Airway Pressure for Central Sleep Apnea and

... nervous system, and it independently increases the risk of death.1,5,6 In short-term, single-center randomized trials lasting one to three months involving small numbers of patients who had central sleep apnea and chronic heart failure, continuous positive airway pressure (CPAP) attenuated the centr ...
Vascular Anesthesia Seminars in Cardiothoracic and
Vascular Anesthesia Seminars in Cardiothoracic and

... using a catheter the left ventricular performance was optimized and “there were no 30-day operative deaths among the [110] patients in this series and only one inhospital mortality (0.9%), four months following surgery. The five-year cumulative survival rate for patients in the present series was 84 ...
CRT - Venice Arrhythmias
CRT - Venice Arrhythmias

... newGonset!HF!in!26%!of!pa>ents!(3.3%!per!yr)! ?  Predictors!for!HF:!Elderly!age!at!the!>me!of!implant,!a!wider!paced!QRS! dura>on!and!the!presence!of!CAD!independently!predicted!newGonset!HF! ?  HF!a`er!RV!apical!pacing!was!associated!with!a!higher!cardiovascular! mortality Zhang&XH,&…..Tse&HF,&et&a ...
A noninvasive algorithm to exclude pre-capillary pulmonary hypertension
A noninvasive algorithm to exclude pre-capillary pulmonary hypertension

... a paper speed of 25 mm?s-1. ECGs were analysed by two cardiologists who were blinded to the clinical and echocardiographic data. ECG rulers and callipers were used. In case of disagreement, consensus was achieved between the two observers in a second reading. The following parameters were obtained: ...
Mechanisms linking red blood cell disorders and cardiovascular diseases
Mechanisms linking red blood cell disorders and cardiovascular diseases

... [3]. Several epidemiological studies investigated possible associations between hemorheological profile and cardiovascular disease; hemorheological alterations may be the cause of the disorder, but they may also result from poor tissue perfusion [4].Hemorheology is the ability of blood to deform, an ...
Patients` drawings illustrate psychological and functional status in
Patients` drawings illustrate psychological and functional status in

... myocardial infarction used patients’ drawings of their heart as an alternative measure of illness perceptions [20,21]. These studies have shown that damage illustrated on heart drawings predicts poorer functional status and negative illness beliefs 3 months after the heart attack and that increases ...
Septal Occluder and Delivery System
Septal Occluder and Delivery System

... Patients indicated for ASD closure have echocardiographic evidence of ostium secundum atrial septal defect and clinical evidence of right ventricular volume overload (such as, 1.5:1 degree of left-to-right shunt or RV enlargement). Contraindications The AMPLATZER Septal Occluder is contraindicated f ...
Depression in Patients Recovering From a Myocardial Infarction
Depression in Patients Recovering From a Myocardial Infarction

... medications as prescribed less often than those without major depression and/or dysthymia. Patients with major depression and/or dysthymia who had diabetes mellitus indicated that they followed a diet for patients with diabetes less often than those without depression. The potential effect of these ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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