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Systematic Review: Comparative Effectiveness of Radiofrequency
Systematic Review: Comparative Effectiveness of Radiofrequency

... 2008 for studies of adults with atrial fibrillation who underwent radiofrequency catheter ablation. We combined keywords and Medical Subject Heading terms for atrial fibrillation, pulmonary vein, radiofrequency ablation, and catheter ablation. We limited the search to Englishlanguage reports of prim ...
Testing for B-type natriuretic peptide in the diagnosis
Testing for B-type natriuretic peptide in the diagnosis

... Adapted, with permission, from: Peacock WF IV. The B-type natriuretic peptide assay: a rapid test for heart failure. Cleve Clin J Med 2002; 69:243–251. ...
Importance of Atrial Flutter Isthmus in Postoperative Intra
Importance of Atrial Flutter Isthmus in Postoperative Intra

... the 6 typical or reverse typical atrial flutters for which bidirectional isthmus block could be demonstrated, only 1 recurred, whereas of the 2 flutters for which bidirectional block could not be demonstrated, both recurred (Table 2). Five patients had attempted repeat ablation that was successful i ...
Intra-aortic balloon pump counterpulsation (IABP) for myocardial
Intra-aortic balloon pump counterpulsation (IABP) for myocardial

... IABP is currently the most commonly used mechanical assist device for patients with cardiogenic shock. Its use is encouraged by a class I recommendation in the American Heart Association (AHA)/American College of Cardiology (ACC) and also the European Society of Cardiology (ESC) guidelines for the m ...
for Cardiopulmonary Resuscitation and Emergency Cardiovascular
for Cardiopulmonary Resuscitation and Emergency Cardiovascular

... There is concern that delivery of chest compressions without assisted ventilation for prolonged periods could be less effective than conventional CPR (compressions plus breaths) because the arterial oxygen content will decrease as CPR duration increases. This concern is especially pertinent in the s ...
Pulmonary Hypertension in the Critically Ill
Pulmonary Hypertension in the Critically Ill

... software that utilizes division into multiple discs and a resultant summation in the overall volume leading to a simple method of calculating CO. This along with the left ventricular outflow tract (LVOT) Doppler method of calculating the cardiac output has been validated in the critically ill popula ...
for Cardiopulmonary Resuscitation and Emergency Cardiovascular
for Cardiopulmonary Resuscitation and Emergency Cardiovascular

... There is concern that delivery of chest compressions without assisted ventilation for prolonged periods could be less effective than conventional CPR (compressions plus breaths) because the arterial oxygen content will decrease as CPR duration increases. This concern is especially pertinent in the s ...
Questions Remaining About the Surgical Correction of Tetralogy of
Questions Remaining About the Surgical Correction of Tetralogy of

... other non-cardiac congenital anomalies in neonates, such as esophageal atresia), the problem of hypoxemia is relieved, allowing a corrective procedure to be carried out at an older age and under much better circumstances. As a consequence, the strategy of neonatal correction in all patients cannot b ...
Catheter Ablation of Supraventricular and Ventricular Arrhythmias
Catheter Ablation of Supraventricular and Ventricular Arrhythmias

... accessory pathways, where the ablation has to be performed from the coronary sinus, there is a risk of damage to the coronary artery or perforation of the venous system leading to cardiac tamponade.13 A Multicentre European Survey25 reported on the complications of radiofrequency catheter ablation i ...
The importance of exercise echocardiography for clinical decision
The importance of exercise echocardiography for clinical decision

... disease, myxomatous degeneration or endocarditis. In secondary mitral regurgitation, the mitral valve is structurally normal but dysfunctional due to ischaemic or non-ischaemic cardiomyopathy. The disease course of primary mitral regurgitation is usually insidious due to progressive atrial and left ...
Oshima 2009
Oshima 2009

... Background—Transforming growth factor-␤ family cytokines have diverse actions in the maintenance of cardiac homeostasis. Activin A is a member of this family whose regulation and function in heart are not well understood at a molecular level. Follistatin-like 3 (Fstl3) is an extracellular regulator ...
Fiber tracking and fiber architecture description in cardiac DT
Fiber tracking and fiber architecture description in cardiac DT

... Cardiovascular disease (CVD) is a class of disease that affects the cardiovascular system, and is a leading cause of death in the world. An estimated 17.3 million people died from CVDs in 2008, representing 30% of all global deaths. Over 80% of CVD deaths take place in low- and middle-income countrie ...
Dreaded Heart Blocks
Dreaded Heart Blocks

... Third degree heart block/ complete heart block 3rd degree heart block indicates complete absence of conduction between atria and ventricles  3rd degree heart block is characterized by a complete dissociation between P waves and ...
Impaired right and left ventricular diastolic
Impaired right and left ventricular diastolic

... Diastolic dysfunction in TOF may stem from impaired myocardial relaxation, decreased recoil attributable to a stiffer ventricle and dyssynchronous ventricular relaxation.3 – 6 However, assessment of RV diastolic dysfunction is difficult using Doppler flow parameters.7 Consequently, RV and LV diastol ...
a sample of the book
a sample of the book

... ulation than others do, such as high -cardiologists. This list includes 2,254 blood pressure and Marfan syndrome, top cardiologists who were selected the number of trusted references identhrough a peer nomination process; tified for each topic varies. 330 of them were also named to a Although heart ...
Mechanical Alternans in Patients With Chronic Heart Failure
Mechanical Alternans in Patients With Chronic Heart Failure

... Mechanical alternans was always accompanied by alternating changes of positive dP/dt, a parameter of contractility during isovolumetric contraction time, but negative dP/dt was occasionally constant. Concordant mechanical alternans between both ventricles was more prevalent than discordant alternans ...
Atrial remodeling due to atrial tachycardia and heart failure
Atrial remodeling due to atrial tachycardia and heart failure

PDF
PDF

... patent ductus arteriosus (PDA) for stent implantation in neonates with duct-dependent pulmonary circulation. Methods: Seven neonates with pulmonary atresia and PDA initially diagnosed with echocardiography who were scheduled for MDCT for evaluation for stent implantation were reviewed. The PDA size ...
SERIES ‘‘PULMONARY HYPERTENSION: BASIC CONCEPTS FOR PRACTICAL MANAGEMENT’’
SERIES ‘‘PULMONARY HYPERTENSION: BASIC CONCEPTS FOR PRACTICAL MANAGEMENT’’

... which the full cardiac cycle can be seen; each movie frame represents 30–40 ms of the cycle. Recent technological advances enable the implementation of SSFP sequences which provide a substantially higher signal-to-noise ratio than can be obtained by conventional gradient–echo techniques. The contras ...
Aneurysms of the Sinuses of Valsalva
Aneurysms of the Sinuses of Valsalva

... Unruptured SVA usually remain asymptomatic and undetected. Previous reports based on necropsy and cardiac surgery findings estimated that 20% of SVA were unruptured [5]. However, with the advent of echocardiography and other noninvasive imaging modalities, unruptured SVA are diagnosed more frequently ...
Secundum atrial septal defect in the adult. Clinical
Secundum atrial septal defect in the adult. Clinical

... but became normal after ASD closure, while left atrial size remained unchanged. The changes that occurred came early and the speed of changes declined with time. From 4 months after closure and on no important changes were observed. The NYHA class improved after ASD closure (p=0.01). 4) ASD closure ...
Sudden Cardiac Arrest During Sports Activity in Middle Age
Sudden Cardiac Arrest During Sports Activity in Middle Age

... a detailed evaluation of the lifetime past medical history is needed, which is particularly challenging to obtain for SCA where the majority will inevitably die in the field, and consequently the information collected by Emergency Medical Services (EMS) is often restricted to data regarding the resu ...
A Comprehensive look At heart structure, function, and health
A Comprehensive look At heart structure, function, and health

... angiotensin II receptor blockers (ARBs) ― group of drugs used to treat high blood pressure ...
Secundum atrial septal defect in the adult. Clinical
Secundum atrial septal defect in the adult. Clinical

... but became normal after ASD closure, while left atrial size remained unchanged. The changes that occurred came early and the speed of changes declined with time. From 4 months after closure and on no important changes were observed. The NYHA class improved after ASD closure (p=0.01). 4) ASD closure ...
Department of Biomedical Engineering
Department of Biomedical Engineering

... forces are applied. Translation and rotation can appear even though the distance remains and thus no deformations occur. The deformations in the cardiac wall are elastic, meaning that once the forces are no longer applied the body returns to its former reference state. Strain describes deformation a ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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