3D Fusion of LV Venous Anatomy on Fluoroscopy Venograms With
... (SPECT) myocardial perfusion imaging (MPI) for guiding cardiac resynchronization therapy (CRT) LV lead placement. BACKGROUND LV lead position is important for CRT response. For LV lead placement into viable regions with late activation, it is important to visualize both LV venous anatomy and myocard ...
... (SPECT) myocardial perfusion imaging (MPI) for guiding cardiac resynchronization therapy (CRT) LV lead placement. BACKGROUND LV lead position is important for CRT response. For LV lead placement into viable regions with late activation, it is important to visualize both LV venous anatomy and myocard ...
Ventriculoarterial Coupling in Normal and Failing Heart in Humans
... however, that the physiological control mechanisms indeed adopt this criterion for optimal coupling between the heart and artery under physiological circumstances in vivo. Another criterion for optimal coupling between an energy source and its load is the principle of economical fuel consumption, or ...
... however, that the physiological control mechanisms indeed adopt this criterion for optimal coupling between the heart and artery under physiological circumstances in vivo. Another criterion for optimal coupling between an energy source and its load is the principle of economical fuel consumption, or ...
Mitochondrial oxidative stress and dysfunction in myocardial
... mitochondrial-encoded gene expression is largely regulated by the copy number of mtDNA.37 Therefore, mitochondrial injury is reflected by mtDNA damage as well as by a decline in the mitochondrial RNA (mtRNA) transcripts, protein synthesis, and mitochondrial function.38,39 We demonstrated that the in ...
... mitochondrial-encoded gene expression is largely regulated by the copy number of mtDNA.37 Therefore, mitochondrial injury is reflected by mtDNA damage as well as by a decline in the mitochondrial RNA (mtRNA) transcripts, protein synthesis, and mitochondrial function.38,39 We demonstrated that the in ...
Left ventricle
... The Pulmonary and Systemic Circuits • Heart is transport system; two side-by-side pumps – Right side receives oxygen-poor blood from tissues • Pumps to lungs to get rid of CO2, pick up O2, via pulmonary circuit ...
... The Pulmonary and Systemic Circuits • Heart is transport system; two side-by-side pumps – Right side receives oxygen-poor blood from tissues • Pumps to lungs to get rid of CO2, pick up O2, via pulmonary circuit ...
Connexin 43 Expression in Human Hypertrophied Heart Due to
... with mild LVH. Five additional patients with mitral regurgitation undergoing mitral valve replacement were enrolled as subjects with LVH due to volume overload. None of the patients had previous ventricular arrhythmic disorders, and none of them had ischemic heart disease. All patients had a normal ...
... with mild LVH. Five additional patients with mitral regurgitation undergoing mitral valve replacement were enrolled as subjects with LVH due to volume overload. None of the patients had previous ventricular arrhythmic disorders, and none of them had ischemic heart disease. All patients had a normal ...
Ventricular Arrhythmias – Approach to Management in Pregnancy
... • Improvement in LVEF, LV dimensions, mitral regurgitation, functional class. • Can take 3-4 months for improvement. • Definitive management is catheter ablation of PVCs • Medical therapy is second-line therapy, with lower chance of success. Long term outcome: • Risk of sudden death remains above ba ...
... • Improvement in LVEF, LV dimensions, mitral regurgitation, functional class. • Can take 3-4 months for improvement. • Definitive management is catheter ablation of PVCs • Medical therapy is second-line therapy, with lower chance of success. Long term outcome: • Risk of sudden death remains above ba ...
Heart Auscultation
... the stethoscope in place. Say, 'Take a big breath in - breathe right out - and hold it'. This will give a few seconds to listen for the murmur. Few people can hold their breath in full expiration for more than a few seconds, especially if unfit. Not all murmurs arise from valves. Some are flow murmu ...
... the stethoscope in place. Say, 'Take a big breath in - breathe right out - and hold it'. This will give a few seconds to listen for the murmur. Few people can hold their breath in full expiration for more than a few seconds, especially if unfit. Not all murmurs arise from valves. Some are flow murmu ...
Cardiogenic shock
... with CS. This device will increase coronary blood flow, decrease left ventricular afterload, and decrease left ventricular end-diastolic pressure without increasing oxygen demand (1, 19, 24). Cardiac output is increased only modestly, and this device does not provide total circulatory support (24). T ...
... with CS. This device will increase coronary blood flow, decrease left ventricular afterload, and decrease left ventricular end-diastolic pressure without increasing oxygen demand (1, 19, 24). Cardiac output is increased only modestly, and this device does not provide total circulatory support (24). T ...
Optimizing Survival from Out-of
... delivery of EMS care (CPR or defibrillation) should be used as the preferred measure of EMS system performance. Both the time of call receipt and the time of the first shock or initiation of CPR can be reliably captured. In our system, we routinely calculate call-to-shock time and call-to-on time by s ...
... delivery of EMS care (CPR or defibrillation) should be used as the preferred measure of EMS system performance. Both the time of call receipt and the time of the first shock or initiation of CPR can be reliably captured. In our system, we routinely calculate call-to-shock time and call-to-on time by s ...
Intermediate Signal Intensity Late Gadolinium Enhancement
... arrhythmia evident.6 Patients included in the analysis were those with visual evid (145/288 or 50% of the cohort) on contrast-enhanced CMR imaging (see below CMR Analysis). Selected patients in this study cohort (n=72) have been part of other analyses.15 Exclusion criteria. During the same time peri ...
... arrhythmia evident.6 Patients included in the analysis were those with visual evid (145/288 or 50% of the cohort) on contrast-enhanced CMR imaging (see below CMR Analysis). Selected patients in this study cohort (n=72) have been part of other analyses.15 Exclusion criteria. During the same time peri ...
2.02.26 Percutaneous LeftAtrial Appendage Closure
... AF leads to blood stasis in the left atrium, and this low flow state increases the risk for thrombosis. The area of the left atrium with the lowest blood flow in AF, and, therefore, the highest risk of thrombosis, is the left atrial appendage (LAA). It has been estimated that 90% of leftatrial throm ...
... AF leads to blood stasis in the left atrium, and this low flow state increases the risk for thrombosis. The area of the left atrium with the lowest blood flow in AF, and, therefore, the highest risk of thrombosis, is the left atrial appendage (LAA). It has been estimated that 90% of leftatrial throm ...
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function
... chelates accumulate in such regions, leading to hyperenhancement on imaging that takes advantage of gadolinium’s T1-shortening effects. ...
... chelates accumulate in such regions, leading to hyperenhancement on imaging that takes advantage of gadolinium’s T1-shortening effects. ...
Therapeutic Hypothermia
... Rewarming begins 12 to 24 hours after the initiation of cooling. Rewarm slowly at a rate of 0.3-0.5 degrees C every hour Remove cooling blankets (and all ice ) One method is to set the water temperature in the cooling device to 35°C, then increase the water temperature by 0.5°C every 1-2 hours until ...
... Rewarming begins 12 to 24 hours after the initiation of cooling. Rewarm slowly at a rate of 0.3-0.5 degrees C every hour Remove cooling blankets (and all ice ) One method is to set the water temperature in the cooling device to 35°C, then increase the water temperature by 0.5°C every 1-2 hours until ...
Baroreceptor stimulation for resistant hypertension
... antihypertensive drugs) enrolled in a European multicentre study [9]. These preliminary data suggested that the procedure had an acceptable safety level, with a low rate of adverse events: one hypoglossal nerve injury (symptoms of hoarseness and eating disturbances), which improved during follow-up, ...
... antihypertensive drugs) enrolled in a European multicentre study [9]. These preliminary data suggested that the procedure had an acceptable safety level, with a low rate of adverse events: one hypoglossal nerve injury (symptoms of hoarseness and eating disturbances), which improved during follow-up, ...
Assessment of clients with CVS conditions
... After administering 0.4 mg of nitroglycerin sublingually to the patient, you and your partner attach the remaining ECG leads and obtain a 12-lead tracing of the patient's cardiac rhythm. As your partner stands up to retrieve the stretcher from the ambulance, you tell him that it looks as though the ...
... After administering 0.4 mg of nitroglycerin sublingually to the patient, you and your partner attach the remaining ECG leads and obtain a 12-lead tracing of the patient's cardiac rhythm. As your partner stands up to retrieve the stretcher from the ambulance, you tell him that it looks as though the ...
Pdf version
... CABG, cardiac 1.5T MRI and 16‑slice CT were performed within 48 hours before surgery. All MRI scans were analyzable; 5 CT exams were excluded due to poor quality. Between‑method agreement was assessed using the analysis of correlation and the Bland‑Altman plots. Results The end‑systolic volume (ES ...
... CABG, cardiac 1.5T MRI and 16‑slice CT were performed within 48 hours before surgery. All MRI scans were analyzable; 5 CT exams were excluded due to poor quality. Between‑method agreement was assessed using the analysis of correlation and the Bland‑Altman plots. Results The end‑systolic volume (ES ...
THE EFFECT OF EXERCISE ON MEAN LEFT VENTRICULAR
... of the systolic ejection period were made, and the average value over at least two respiratory cycles was derived. In those cases with atrial fibrillation the average was derived from a minimum of 12 complexes. Those cases in which the systolic ejection period was not clearly defined on the arterial ...
... of the systolic ejection period were made, and the average value over at least two respiratory cycles was derived. In those cases with atrial fibrillation the average was derived from a minimum of 12 complexes. Those cases in which the systolic ejection period was not clearly defined on the arterial ...
Theme 9. Management of the patients with stable angina
... Angina is also associated with major social and economic burdens. Because of poor symptom control and hemodynamic, as well as other drug side effects, angina is commonly associated with a poor quality of life (QOL). No new class of drug has been available for angina treatment in more than two decade ...
... Angina is also associated with major social and economic burdens. Because of poor symptom control and hemodynamic, as well as other drug side effects, angina is commonly associated with a poor quality of life (QOL). No new class of drug has been available for angina treatment in more than two decade ...
Dobutamine stress for evaluation of right ventricular reserve in pulmonary arterial hypertension
... chosen for safety reasons to ensure that very high heart rates were not induced in patients with PAH, which could precipitate RV ischaemia. Side-effects requiring cessation of infusion were defined as: 1) hypotension (systolic blood pressure <85 mmHg); 2) chest pain; 3) new onset arrhythmias; or 4) ...
... chosen for safety reasons to ensure that very high heart rates were not induced in patients with PAH, which could precipitate RV ischaemia. Side-effects requiring cessation of infusion were defined as: 1) hypotension (systolic blood pressure <85 mmHg); 2) chest pain; 3) new onset arrhythmias; or 4) ...
Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?
... study performed by Rosengren et al. showed that 3% of type 1 diabetic patients were admitted to a hospital over a mean follow-up of 7.9 years with a diagnosis of heart failure compared to 1% of matched controls. The incidence rates for any heart failure diagnosis were 4.0 per 1000 person-years in di ...
... study performed by Rosengren et al. showed that 3% of type 1 diabetic patients were admitted to a hospital over a mean follow-up of 7.9 years with a diagnosis of heart failure compared to 1% of matched controls. The incidence rates for any heart failure diagnosis were 4.0 per 1000 person-years in di ...
Surgical treatment of congenital coronary artery
... Possible therapy for the management of CCAF includes prophylaxis of endocarditis, transcatheter embolization, and surgical ligation of fistula, but most surgeons also suggest that surgical ligation should be considered as the gold standard.[11] Surgical closure by vessel ligation has been the most c ...
... Possible therapy for the management of CCAF includes prophylaxis of endocarditis, transcatheter embolization, and surgical ligation of fistula, but most surgeons also suggest that surgical ligation should be considered as the gold standard.[11] Surgical closure by vessel ligation has been the most c ...
Thoracic Radiology
... measured along the length of the thoracic vertebrae commencing at the cranial aspect of T4. The vertebral length is noted. At right angles to the first measurement and at the maximal heart width a second measurement is made and again laid against the thoracic vertebra commencing at T4. The two verte ...
... measured along the length of the thoracic vertebrae commencing at the cranial aspect of T4. The vertebral length is noted. At right angles to the first measurement and at the maximal heart width a second measurement is made and again laid against the thoracic vertebra commencing at T4. The two verte ...
narrow-qrs tachycardias
... demand for oxygen increases as the heart rate increases. As the heart rate increases, there is less time for the ventricles to fill and less blood for the ventricles to pump out with each contraction. This can lead to decreased cardiac output. Because the coronary arteries fill when the ventricles a ...
... demand for oxygen increases as the heart rate increases. As the heart rate increases, there is less time for the ventricles to fill and less blood for the ventricles to pump out with each contraction. This can lead to decreased cardiac output. Because the coronary arteries fill when the ventricles a ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.