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Adenosine-Provoked Atrial Fibrillation Originating From€Non
Adenosine-Provoked Atrial Fibrillation Originating From€Non

... to determine the predictors of recurrent arrhythmias. Variables whose univariable analyses had p values <0.05 were included in the multivariable Cox regression model. A Kaplan-Meier analysis was used to determine the percentage of patients free from recurrence. The difference in the arrhythmia-free ...
THE CARDIAC IMPULSE AND THE MOTION OF THE HEART
THE CARDIAC IMPULSE AND THE MOTION OF THE HEART

... was relatively small, and that its outward movement always terminated well before the second heart sound. The impulse cardiogram showed the length of the impulse in relation to the heart sounds and it was noted that it always ended before the last third of systole (Fig. 5). In analysing the apical i ...
[Type text] RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES
[Type text] RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

... The importance of bystander-initiated cardiopulmonary resuscitation (CPR) has been clearly demonstrated. Bystander CPR followed by advanced cardiac life support has been shown to be effective in the treatment of out-of-hospital sudden cardiac death both in terms of improving the long term survival o ...
ATRIAL FIBRILLATION IN CHILDHOOD WITH FAMILIAL
ATRIAL FIBRILLATION IN CHILDHOOD WITH FAMILIAL

... For the past 180 years, the medical literature has been replete with documented genes e.g. LMNA and SCNRA, and chromosomes, which can be autosomal dominant e.g. 10q22-24, and autosomal recessive e.g. 5p13, and ways that hyperthyroid states may affect the heart. These data point to multifactorial rea ...
Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia and
Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia and

... total cardiac mortality rate of 3%, the annual sudden death mortality reaches 2% or more.19,32 The mechanism of sudden death in ARVC is mostly acceleration of ventricular tachycardia with degeneration into ventricular fibrillation.32 Studies from arrhythmia referral centres have shown that severe ri ...
Impact of Manual CPR on Increasing Coronary Perfusion
Impact of Manual CPR on Increasing Coronary Perfusion

... correctly.11 Furthermore, most rescuers did not perceive any fatigue until after 3 minutes. And 26% of those studied did not perceive any fatigue after 5 minutes, even though a decrease in performance was observed after only 1 minute. Based on this study and a similar study of EMS rescuers by Highto ...
EKG Clues
EKG Clues

... Utter Confusion • Verify lead placement • Repeat EKG • Repeat standardized process of EKG analysisstarting over from the beginning with basics – rate, intervals, axis, rhythm, etc. and proceed through entire stepwise analysis • Consider Cardiology consultation ...
Tetraparesis and Failure of Pacemaker Capture Induced by Severe
Tetraparesis and Failure of Pacemaker Capture Induced by Severe

... The effects of hyperkalemia on the heart are very dangerous and are related to both the absolute value of serum potassium, which modifies the Ke/Ki ratio, and the rapidity of the increase. Hyperkalemia reduces the resting potential and, consequently, restricts the difference between the resting and ...
R P V C
R P V C

... discussed in this Thesis. Associated lesions include atrial septal defect (35%)2, right aortic arch with mirror image branching (20-25%)2, anomalous coronary artery (5-7%)3, and complete atrioventricular septal defect (rare, usually in association with Down ...
Level of Evidence: C - Professional Heart Daily
Level of Evidence: C - Professional Heart Daily

... should be performed during initial evaluation of patients presenting with HF to assess left ventricular ejection fraction (LVEF), LV size, wall thickness, and valve function. Radionuclide ventriculography can be performed to assess LVEF and volumes. (Level of Evidence: C) ...
In Vitro Tools for Quantifying Structure– Function Relationships in
In Vitro Tools for Quantifying Structure– Function Relationships in

... expression remodel through cardiac development and disease, these components together are thought to regulate the phenotype of cardiac myocytes. To investigate this, isolated cardiac myocytes have been cultured on substrates coated with different matrix proteins, revealing that matrix composition re ...
second-messenger systems underlying amine and pepttde actions
second-messenger systems underlying amine and pepttde actions

... using the intact Limulus heart preparation, since amine-induced increases in heart rate decrease their overall inotropic action (Watson etal. 1985). Therefore, to assess the excitatory effect of amines on cardiac muscle contractility, deganglionated myocardial rings were prepared and contractions we ...
2016 IJC-D-16-00650_R1_FINAL_SUBMIT_figs
2016 IJC-D-16-00650_R1_FINAL_SUBMIT_figs

... undergoing coronary surgery using a high-density array in sinus rhythm (NSR). RA burst pacing at 200/500/1000ms cycle lengths (CL) was performed, recording episodes of AF>30s. Co-localised RA tissue was snap frozen for RNA and protein extraction. Results: Electrograms prolonged during AF (76.64±29.3 ...
quantitative echocardiographic methods for
quantitative echocardiographic methods for

... quantitative measurement of the hearts function and haemodynamics and following ...
Colchicine for Prevention of Post
Colchicine for Prevention of Post

Single Chamber and Dual Chamber Permanent Cardiac Pacemakers
Single Chamber and Dual Chamber Permanent Cardiac Pacemakers

... UnitedHealthcare follows Medicare coverage guidelines and regularly updates its Medicare Advantage Policy Guidelines to comply with changes in CMS policy. UnitedHealthcare encourages physicians and other healthcare professionals to keep current with any CMS policy changes and/or billing requirements ...
Interrelationships of Hepatic Blood Flow
Interrelationships of Hepatic Blood Flow

... than 2.5 liters/min/m2 and those with an index above this value. The average cardiac index for those with a low cardiac output was 1.9 ± 0.3 (sEM ) liters/min/m2, while the group with a normal cardiac index averaged 3.3 + 0.8 (SEM) liters/min/m2. At the same rate of infusion, the steady-state arteri ...
Comprehensive Dobutamine Stress CMR Versus Echocardiography
Comprehensive Dobutamine Stress CMR Versus Echocardiography

... images were acquired. This dose was selected due to our previous clinical experience suggesting that at higher doses of dobutamine, the increase in contractility and heart rate makes it difficult to qualitatively interpret the first-pass perfusion images. Furthermore, there is also some evidence that ...
Symptoms In Atrial Fibrillation: A Contemporary Review And
Symptoms In Atrial Fibrillation: A Contemporary Review And

... functional status and HRQOL are strong predictors of all-cause and cardiovascular hospitalizations in patients with AF.13 Furthermore, symptoms contribute to the increase in invasive cardiovascular procedures, medication use, and health care resources utilization. Therefore, improvement of symptoms ...
Survival after balloon atrial septostomy for complete transposition of
Survival after balloon atrial septostomy for complete transposition of

... This may be attributed to the smaller number of patients and incomplete data for some variables. Other studies have shown that cerebrovascular accidents and cerebral abscesses occur after septostomy,20 21 as was seen in three of our patients. Of note was that prostaglandin E2 infusions did not signi ...
undergoing valve replacement Mitral regurgitation in patients with
undergoing valve replacement Mitral regurgitation in patients with

... AVR provided significantly better event-free survival than double valve replacement.[16] When MR is less severe, and keeping in mind the good results of double valve surgery,[13] some groups have recommended an aggressive approach to operating on the mitral valve, supported by data showing that conc ...
Effects of insulin on the cardiac autonomic nervous system in insulin
Effects of insulin on the cardiac autonomic nervous system in insulin

... such as obese subjects (n ¯ 20) and those with hypertension (n ¯ 15) or type II (non-insulindependent) diabetes (n ¯ 22). Healthy subjects and patients underwent euglycaemic hyperinsulinaemic glucose clamp, and cardiac ANS and haemodynamic changes were investigated by continuous recording of heart r ...
Sudden Cardiac Death
Sudden Cardiac Death

... decreasing platelet adhesiveness and aggregability.22 Furthermore, acute bouts of exercise accentuates the sympathetic nervous system and decreases vagal activity, which can lead to an acute increase in susceptibility to ventricular fibrillation.23 In contrast, regular vigorous exertion increases va ...
Secundum type atrial septal defect with prolonged PR - Heart
Secundum type atrial septal defect with prolonged PR - Heart

... This report describes a family where secundum type atrial septal defect with prolonged atrioventricular conduction time occurred certainly in 6, andprobably in at least I more, members of thefamily in 3 or 4 generations. No skeletal anomalies were found. Because of a certain type of kinship in two a ...
Sports related rehabilitation following myocardial infarction
Sports related rehabilitation following myocardial infarction

... of all ages, in hospital or community settings, who have had myocardial infarction, coronary artery bypass graft or percutaneous transluminal coronary angioplasty, or who have angina pectoris or coronary artery disease defined by angiography. DATA COLLECTION AND ANALYSIS: Studies were selected indep ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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