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consensus statement of the uiaa medical commission vol: 21
consensus statement of the uiaa medical commission vol: 21

... Very rapidly, however, for yet unknown reasons, the direct hypoxia-induced vasodilatation decreases and the adrenal medullary response increases causing an increase in systemic vascular resistance and systemic blood pressure [9]. The stimulation of the cardiovascular system reaches its maximum effec ...
Abnormal electrocardiographic findings in athletes
Abnormal electrocardiographic findings in athletes

... root of the shortest RR interval,27 which will grossly overestimate the QTc. Instead, it is more accurate to derive an average QT interval and average RR interval. Fourth, to perform a manual confirmation, the critical issue is identifying the end of the T wave since the onset of the QRS is seen easi ...
ACLS-ECG-Slides - UCSF Department of Anesthesia and
ACLS-ECG-Slides - UCSF Department of Anesthesia and

... sinus node at a rate appropriate to the age and state of activity of the individual, and then the propagation of that signal in an orderly manner through the atria, AV junction, ventricular specialized conducting system and the ventricular myocardium ...


... Studies have found that TTE may overestimate pulmonary artery pressures compared with right heart catheterization (RHC).3 On the other hand, in about one-third of patients, RHC may reveal more severe PH than is estimated from TTE. Thus, both under- and overestimating may occur. However, PH does not ...
Introduction to Echocardiography
Introduction to Echocardiography

... wall of the heart makes this approach ideal for examining several important structures. Second, the ability to position the transducer in the esophagus or stomach for extended periods provides an opportunity to monitor the heart over time, such as during cardiac surgery.Third, although more invasive ...
circ.ahajournals.org
circ.ahajournals.org

... urgical treatment has improved the long-term prognosis of patients with congenital heart disease (CHD), but late ventricular arrhythmias remain a risk for patients who have had ventriculotomies.1,2 After repair of tetralogy of Fallot (TOF), the incidence of ventricular tachycardia (VT) is 11.9%, wit ...
B-type natriuretic peptide levels predict outcome after neonatal
B-type natriuretic peptide levels predict outcome after neonatal

... urgical repair or palliation of congenital cardiac defects is performed routinely in the neonatal period. Neonates, in comparison with infants and children, have adverse events more often and have greater perioperative mortality. Although risk-adjustment scoring systems and various biomarkers have b ...
Application of mechanical circulatory support in
Application of mechanical circulatory support in

... the end of heart surgery; for case 2, the emergency cannulation was given at the bedside through right common carotid artery and right internal jugular venous cannulation to establish ECMO. Provided that the cannula models and size are selected appropriately, ECMO can be established quickly in the t ...
Diagnostic accuracy of myocardial deformation indices for detecting
Diagnostic accuracy of myocardial deformation indices for detecting

... Abstract: Background: The prediction of coronary artery disease (CAD) by conventional echocardiographic measurements is principally based on the estimation of ejection fraction and regional wall motion abnormality (RWMA). This study aimed to determine whether strain echocardiography of left ventricl ...
Closed-loop cardiac pacing vs. conventional dual
Closed-loop cardiac pacing vs. conventional dual

... for faster detection of a significant rate drop and respond by pacing at a high rate, reduces syncope in patients with severe forms of neurocardiogenic syncope8,12,14 – 17 and may be preferable to the DDI pacing mode with rate hysteresis.18 Closed Loop Stimulationw (CLS) function, performed by INOS2 ...
Atrial Septal defect (ASD) Device Closure in Detail
Atrial Septal defect (ASD) Device Closure in Detail

... family members having heart disease etc are high risk factors. STEP II: Now what to do? Visit your child specialist. The pediatrician hears your child’s chest with a stethoscope and can diagnose abnormal sounds called murmurs. He will also check the Blood pressure, pulses and measure the oxygen perc ...
Direct Percutaneous Left Ventricular Access and Port Closure
Direct Percutaneous Left Ventricular Access and Port Closure

... (Fig. 4C). As expected during myocardial traversal, cardiac troponin I levels increased from 0 (interquartile range [IQR]: 0 to 0.04) at baseline to 0.39 (IQR: 0.2 to 0.9) ng/ml at 3 h (p ⫽ 0.004). All animals had early (day 5 ⫾ 1) pericardial fluid accumulation. Because it was not feasible to leave ...
The endurance athletes heart: acute stress and chronic adaptation
The endurance athletes heart: acute stress and chronic adaptation

... area of diagnostic uncertainty. Approximately 80% of nontraumatic sudden deaths in young athletes are caused by inherited or congenital cardiac defects of which HCM is the most common pathology associated with sudden cardiac death.29 Superior athletic performance can co-exist with a hereditary cardi ...
Reduce Infarct Size
Reduce Infarct Size

... • Myocardial reperfusion injury first postulated by Jennings and co-workers in 1960 • Injury that occurs to the heart during reperfusion causes four types of dysfunction – Myocardial stunning- dysfunction post reperfusion despite absence of irreversible damage – No-reflow phenomenon – impedence of m ...
Diagnostic and Therapeutic Cardiovascular Procedures
Diagnostic and Therapeutic Cardiovascular Procedures

... cava saturation⫹inferior vena cava saturation)/4. This is most accurate in low-output states and is considered the “gold standard.” In the thermodilution technique, a known amount of solution (usually saline) is injected into the proximal port (right atrium), where it mixes and cools the blood, whic ...
Circulation Research
Circulation Research

... In three experiments, afferent pathways between the pericoronary nerve and stellate ganglion or sympathetic trunk were investigated. Pressor response to pericoronary nerve stimulation was demonstrated after bilateral cervical vagotomy and right stellectomy. Sequential sectioning of the left inferior ...
Arrhythmia/Electrophysiology
Arrhythmia/Electrophysiology

... urgical treatment has improved the long-term prognosis of patients with congenital heart disease (CHD), but late ventricular arrhythmias remain a risk for patients who have had ventriculotomies.1,2 After repair of tetralogy of Fallot (TOF), the incidence of ventricular tachycardia (VT) is 11.9%, wit ...
ECG
ECG

...  Characterized by irregular ventricular rhythm and absence of P wave  Difficult to get adequate pacing trigger for gated studies ...
Ventricular Tachycardia during Treatment with Modafinil
Ventricular Tachycardia during Treatment with Modafinil

... The ECG revealed normal sinus rhythm of 68 beats/min with intermediate axis, a normal PR-interval (140 ms), and normal QRS-duration (80 ms) and QTinterval (360 ms), and nonspecific ST-segment abnormalities (Figure 1). Shortly after admission, telemetric monitoring showed two short-lasting episodes o ...
Mitral Valve Repair
Mitral Valve Repair

... severe mitral regurgitation especially in the younger age groups. It is possible that younger patients have a greater compensatory mechanism, and the older patients simply adjust their daily activities based on their exertion tolerance. Therefore, it is not uncommon to find patients with severe mitr ...
and George F. Van Hare Krucoff, Michael M. Laks, Peter W
and George F. Van Hare Krucoff, Michael M. Laks, Peter W

Global Bi-ventricular endocardial distribution of activation rate
Global Bi-ventricular endocardial distribution of activation rate

... detectable difference in the AR between them. When analyzing the distribution of the AR within the bi-ventricles at 3 min of LDVF, the posterior LV was activated fastest, while the anterior was slowest. In the HF group, a detectable AR gradient existed between the two ventricles within 3 min of VF, ...
Heart rate variability in patients with stable angina
Heart rate variability in patients with stable angina

... reduces heart rate. Furthermore, as described already long ago, the two divisions of the autonomic system interact both at centers in the central nervous system and within the heart itself.4, 5 These interactions between the sympathetic and parasympathetic limbs determine their respective effects on ...
Gross Anatomy of the Heart
Gross Anatomy of the Heart

... and, consequently, is a more likely site for ventricular septal ...
Understanding your child`s heart Large ventricular septal defect
Understanding your child`s heart Large ventricular septal defect

... successful and carries a very low risk of death. There are small risks of complications such as brain damage, kidney damage, damage to the heart’s electrical system (which may need treatment with a pacemaker), or serious lung infections such as pneumonia. It is not unusual for there to be still a sm ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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