The thesis
... Mechanical functions of the PF relate to its viscous nature and that it is situated in a subatmospheric pressure condition. PF - due to its viscous characteristics - reduces the friction between the surface of the heart and the pericardium, thereby ensuring the smooth movement of the heart during ev ...
... Mechanical functions of the PF relate to its viscous nature and that it is situated in a subatmospheric pressure condition. PF - due to its viscous characteristics - reduces the friction between the surface of the heart and the pericardium, thereby ensuring the smooth movement of the heart during ev ...
Decreased Nox4 levels in the myocardium of patients with aortic
... Nox4 by pressure overload and no data are available on human myocardial Nox4. In the present study, we evaluated Nox4 expression and its relationship with myocardial remodelling and LV (left ventricular) function in patients with severe AS (aortic valve stenosis). Endomyocardial biopsies from 34 pat ...
... Nox4 by pressure overload and no data are available on human myocardial Nox4. In the present study, we evaluated Nox4 expression and its relationship with myocardial remodelling and LV (left ventricular) function in patients with severe AS (aortic valve stenosis). Endomyocardial biopsies from 34 pat ...
Sodium Ion Transporters as New Therapeutic Targets in Heart Failure
... Abstract: Sodium ion transporters in sarcolemma are involved in numerous vital cell functions, such as excitability, excitationcontraction coupling, energy metabolism, pH and volume regulation, development and growth. In a number of cardiac pathologies, the intracellular sodium concentration ([Na+]i ...
... Abstract: Sodium ion transporters in sarcolemma are involved in numerous vital cell functions, such as excitability, excitationcontraction coupling, energy metabolism, pH and volume regulation, development and growth. In a number of cardiac pathologies, the intracellular sodium concentration ([Na+]i ...
patent ductus arteriosus with pulmonary hypertension - Heart
... cyanosis was so marked as to be discernable by them. The symptoms described above occurred with such frequency in patients with this anomaly as to be considered characteristic of it, but they are not pathognomonic of it since similar symptoms are a feature of other congenital defects such as atrial ...
... cyanosis was so marked as to be discernable by them. The symptoms described above occurred with such frequency in patients with this anomaly as to be considered characteristic of it, but they are not pathognomonic of it since similar symptoms are a feature of other congenital defects such as atrial ...
Cardiac repolarization analysis using the surface - DIEC
... In this section, a review of ECG indices proposed in the literature to assess spatial heterogeneity of ventricular repolarization is presented, together with their value for assessing the risk of suffering from malignant ventricular arrhythmias. (a ) Dispersion of repolarization reflected on ECG inte ...
... In this section, a review of ECG indices proposed in the literature to assess spatial heterogeneity of ventricular repolarization is presented, together with their value for assessing the risk of suffering from malignant ventricular arrhythmias. (a ) Dispersion of repolarization reflected on ECG inte ...
Full Text - Journal of Preventive Cardiology
... short QT syndrome, etc are associated with significant risk of SCD. ...
... short QT syndrome, etc are associated with significant risk of SCD. ...
Arrhythmia Risk and Arterial Stiffness
... atrial fibrillation and heart failure hospitalization, pacemaker implantation, adverse cardiovascular outcomes and all-cause mortality [23-25]. PR interval lenght was independently associated with endothelial dysfunction and increased arterial stiffness, in a study including 88 healthy subjects, wit ...
... atrial fibrillation and heart failure hospitalization, pacemaker implantation, adverse cardiovascular outcomes and all-cause mortality [23-25]. PR interval lenght was independently associated with endothelial dysfunction and increased arterial stiffness, in a study including 88 healthy subjects, wit ...
Fig. 11 - JACC: Cardiovascular Imaging
... valve leaflets, which are attached throughout the length of the aortic root. The aortic valve annulus typically represents the tightest part of the aortic root and is defined as a virtual ring with 3 anatomical anchor points at the base of each of the attachments of the aortic leaflets (Fig. 1). The ...
... valve leaflets, which are attached throughout the length of the aortic root. The aortic valve annulus typically represents the tightest part of the aortic root and is defined as a virtual ring with 3 anatomical anchor points at the base of each of the attachments of the aortic leaflets (Fig. 1). The ...
Neurocardiogenic Syncope
... 1) Patients with unexplained syncope, near syncope, or episodesic dizziness in whom the cause is not obvious 2) Patients with unexplained recurrent palpitation Class IIb 1) Patients with episodic shortness of breath, chest pain hat that is not otherwise explained 2) Patient with neurological events ...
... 1) Patients with unexplained syncope, near syncope, or episodesic dizziness in whom the cause is not obvious 2) Patients with unexplained recurrent palpitation Class IIb 1) Patients with episodic shortness of breath, chest pain hat that is not otherwise explained 2) Patient with neurological events ...
Inherited heart conditions Dilated cardiomyopathy In association with
... Other conditions – such as coronary heart disease, high blood pressure (hypertension), or heart valve disease – can also cause the heart to become dilated and these conditions can also lead to the symptoms of heart failure. So, if you have symptoms of heart failure, your doctor will need to do tests ...
... Other conditions – such as coronary heart disease, high blood pressure (hypertension), or heart valve disease – can also cause the heart to become dilated and these conditions can also lead to the symptoms of heart failure. So, if you have symptoms of heart failure, your doctor will need to do tests ...
and Absence of Coronary Sinus
... 7) uncertainty still exists as to whether an atrial septal defect is present. In this case, the atrial aspect of the heart was not explored at the time of operation. In the condition under consideration, an intracardiac right-to-left shunt forms part of the functional abnormality. It is of interest ...
... 7) uncertainty still exists as to whether an atrial septal defect is present. In this case, the atrial aspect of the heart was not explored at the time of operation. In the condition under consideration, an intracardiac right-to-left shunt forms part of the functional abnormality. It is of interest ...
Echocardiographic Investigation of Canine Myxomatous Mitral
... they insert and the location of insertion on the leaflet.9 The total number of chordae tendineae in dogs2 is approximately twice the number reported in humans.9 It has also been shown that there are a significantly higher number of chordae tendineae attaching to the anterior mitral valve leaflet ver ...
... they insert and the location of insertion on the leaflet.9 The total number of chordae tendineae in dogs2 is approximately twice the number reported in humans.9 It has also been shown that there are a significantly higher number of chordae tendineae attaching to the anterior mitral valve leaflet ver ...
Stress-dependent cardiac remodeling occurs in the absence of
... n = 6 for sham conditions and n = 12 for TAC conditions. (C) Northern blot analysis for miR-21 in cardiac tissue of animals treated as indicated. The upshift reflects a heteroduplex between miR-21 and antimiR-21. RNU6B was a loading control. (D) Real-time RT-PCR analysis of miR-21 expression in card ...
... n = 6 for sham conditions and n = 12 for TAC conditions. (C) Northern blot analysis for miR-21 in cardiac tissue of animals treated as indicated. The upshift reflects a heteroduplex between miR-21 and antimiR-21. RNU6B was a loading control. (D) Real-time RT-PCR analysis of miR-21 expression in card ...
Cardiogenesis in the bovine to 35 somites - K-REx
... form the left chambers of the heart from the left primordium and the right chambers from the right heart tube. ...
... form the left chambers of the heart from the left primordium and the right chambers from the right heart tube. ...
Characterization and Modeling of the Purkinje System for Biophysical Simulations
... Because of the challenges for identifying conductive tissue, there has been considerable wheel spinning over the last century, often leading to contradictory results, thus controversy abounded. This is partly due to the lack of markers for this specific tissue. The understanding of the PK pattern wa ...
... Because of the challenges for identifying conductive tissue, there has been considerable wheel spinning over the last century, often leading to contradictory results, thus controversy abounded. This is partly due to the lack of markers for this specific tissue. The understanding of the PK pattern wa ...
Disordered Myocardial Ca2+ Homeostasis Results
... channel function (e.g. drugs, oxidative stress). Despite progressive current therapies both VF and AF remains a major health problem. Further understanding of the mechanisms and factors responsible for the onset and maintenance of these arrhythmias is essential. We have previously shown (Tribulova e ...
... channel function (e.g. drugs, oxidative stress). Despite progressive current therapies both VF and AF remains a major health problem. Further understanding of the mechanisms and factors responsible for the onset and maintenance of these arrhythmias is essential. We have previously shown (Tribulova e ...
Here - The Egyptian Cardiac Rhythm Association
... electrophysiologic study. Recurrent ventricular tachycardia was defined as well tolerated to allow adequate mapping when systolic pressure was ⬎70 mm Hg with no signs of low cerebral flow or cardiac output. These patients were selected to undergo radiofrequency energy (RF) ablation. The VT was inces ...
... electrophysiologic study. Recurrent ventricular tachycardia was defined as well tolerated to allow adequate mapping when systolic pressure was ⬎70 mm Hg with no signs of low cerebral flow or cardiac output. These patients were selected to undergo radiofrequency energy (RF) ablation. The VT was inces ...
Brugada Syndrome (2015)
... The most typical presentation is syncope or resuscitated sudden death in the third or fourth decade of life due to polymorphic ventricular tachycardia (VT) or ventricular fibrillation (VF). Symptoms typically occur at night, or at rest during the day but also uncommonly during exer ...
... The most typical presentation is syncope or resuscitated sudden death in the third or fourth decade of life due to polymorphic ventricular tachycardia (VT) or ventricular fibrillation (VF). Symptoms typically occur at night, or at rest during the day but also uncommonly during exer ...
Intercapillary Distance and Capillary Reserve in Hypertrophied Rat
... WEARN et al.1-2 were the first to report that myocardial capillary circulation is compromised by the hypertrophy of disease. They concluded that neither the fibers nor the capillaries proliferate, and that the distance between capillaries increases because fiber diameter increases. This view has bee ...
... WEARN et al.1-2 were the first to report that myocardial capillary circulation is compromised by the hypertrophy of disease. They concluded that neither the fibers nor the capillaries proliferate, and that the distance between capillaries increases because fiber diameter increases. This view has bee ...
Intercapillary Distance and Capillary Reserve in
... WEARN et al.1-2 were the first to report that myocardial capillary circulation is compromised by the hypertrophy of disease. They concluded that neither the fibers nor the capillaries proliferate, and that the distance between capillaries increases because fiber diameter increases. This view has bee ...
... WEARN et al.1-2 were the first to report that myocardial capillary circulation is compromised by the hypertrophy of disease. They concluded that neither the fibers nor the capillaries proliferate, and that the distance between capillaries increases because fiber diameter increases. This view has bee ...
Print - Circulation
... and IV patients.12 Nearly half of these deaths occur suddenly,3 primarily from ventricular tachycardia (VT) degenerating to ventricular fibrillation (VF).4 Current antiarrhythmic therapy is nonspecific, ineffective,5 and potentially proarrhythmic6,7 and can cause hemodynamic and clinical deteriorati ...
... and IV patients.12 Nearly half of these deaths occur suddenly,3 primarily from ventricular tachycardia (VT) degenerating to ventricular fibrillation (VF).4 Current antiarrhythmic therapy is nonspecific, ineffective,5 and potentially proarrhythmic6,7 and can cause hemodynamic and clinical deteriorati ...
UTILISATION OF CARDIAC MAGNETIC RESONANCE
... ever-growing scientific medical knowledge. Cardiac magnetic resonance (CMR) being the latest addition to the clinical armamentarium of cardiovascular imaging is certainly no different. The importance of CMR is such that today it has already become the gold standard clinical test in some cardiac dise ...
... ever-growing scientific medical knowledge. Cardiac magnetic resonance (CMR) being the latest addition to the clinical armamentarium of cardiovascular imaging is certainly no different. The importance of CMR is such that today it has already become the gold standard clinical test in some cardiac dise ...
PDF
... with the animals standing on the treadmill. Meanwhile, the six exercise data-points were recorded during the last 30s of each stage in the submaximal stress protocol (i.e., L1—L6). In addition, exercise-induced changes in the ECG morphology as well as on ECG-derived indices of the duration and heter ...
... with the animals standing on the treadmill. Meanwhile, the six exercise data-points were recorded during the last 30s of each stage in the submaximal stress protocol (i.e., L1—L6). In addition, exercise-induced changes in the ECG morphology as well as on ECG-derived indices of the duration and heter ...
Left Ventricular Diastolic Mechanical Dyssynchrony and Associated
... systolic and diastolic heart failure and may be associated with ventricular dysfunction and poor outcome.4 –10 However, diastolic wall motion has not been well delineated in children in general, and diastolic mechanical dyssynchrony has not been studied in children with DCM. Therefore, the objective ...
... systolic and diastolic heart failure and may be associated with ventricular dysfunction and poor outcome.4 –10 However, diastolic wall motion has not been well delineated in children in general, and diastolic mechanical dyssynchrony has not been studied in children with DCM. Therefore, the objective ...
Congenital pericardial defects
... radiograph (Fig. 4) showed all the features of an absent left pericardium. The electrocardiogram showed sinus rhythm with a mean frontal QRS vector of approximately + 60'. Some of the leads showed total electrical alternans which involved the frontal QRS vector and possibly the P vector, and was mos ...
... radiograph (Fig. 4) showed all the features of an absent left pericardium. The electrocardiogram showed sinus rhythm with a mean frontal QRS vector of approximately + 60'. Some of the leads showed total electrical alternans which involved the frontal QRS vector and possibly the P vector, and was mos ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.