Curriculum Vitae - The Royal Children`s Hospital
... Augustin SL, Horton S, Thuys C, Bennett M, Claessen C, Brizard CP. Perfusion. 2006 Mar;21(2):121-5 ...
... Augustin SL, Horton S, Thuys C, Bennett M, Claessen C, Brizard CP. Perfusion. 2006 Mar;21(2):121-5 ...
Hypoplastic Left Heart Syndrome: Echocardiographic Assessment
... • Hypoplastic ascending aorta – <5 mm, usually smaller – Main coronary artery – Fills retrograde from ductus arteriosus • Aorta becomes larger at 1st arch vessel, but not normal until distal to PDA • Aortic arch branching pattern • Juxtaductal posterior shelf/coarctation ...
... • Hypoplastic ascending aorta – <5 mm, usually smaller – Main coronary artery – Fills retrograde from ductus arteriosus • Aorta becomes larger at 1st arch vessel, but not normal until distal to PDA • Aortic arch branching pattern • Juxtaductal posterior shelf/coarctation ...
Comparison of estimations versus measured resting oxygen
... Affecting close to 6 million people in the United States, heart failure (HF) represents the final stage of several diseases of the heart and is commonly defined as a reduction in the heart’s ability to circulate blood. Cardiac output during right heart catheterization is an important variable used i ...
... Affecting close to 6 million people in the United States, heart failure (HF) represents the final stage of several diseases of the heart and is commonly defined as a reduction in the heart’s ability to circulate blood. Cardiac output during right heart catheterization is an important variable used i ...
Management of patients with palpitations: a position paper from the
... obtained from general practitioners found no difference in 5-year mortality and morbidity between patients with palpitations and a group of asymptomatic control subjects.4 Also in the abovementioned study by Weber and Kapoor47 on a general population of patients presenting with palpitations at an un ...
... obtained from general practitioners found no difference in 5-year mortality and morbidity between patients with palpitations and a group of asymptomatic control subjects.4 Also in the abovementioned study by Weber and Kapoor47 on a general population of patients presenting with palpitations at an un ...
Computational Modeling of Aortic Heart Valves
... more accurately recreates the multilayered anisotropic leaflet as compared to the simple isotropic model. This fiber-reinforced model greatly reduced peak systolic stresses in the leaflets, compressive and tensile. The fiber-reinforcement also stabilized the leaflets during opening and closing, elim ...
... more accurately recreates the multilayered anisotropic leaflet as compared to the simple isotropic model. This fiber-reinforced model greatly reduced peak systolic stresses in the leaflets, compressive and tensile. The fiber-reinforcement also stabilized the leaflets during opening and closing, elim ...
Chapter 35 - Extras Springer
... echocardiography. Echocardiography is a versatile, low-cost, and portable technique that is available clinically in nearly all medical centers and subsequently is the most widely utilized cardiac testing modality. The diagnosis of CAD by echocardiography is based on the concept that acute myocardial ...
... echocardiography. Echocardiography is a versatile, low-cost, and portable technique that is available clinically in nearly all medical centers and subsequently is the most widely utilized cardiac testing modality. The diagnosis of CAD by echocardiography is based on the concept that acute myocardial ...
Factors influencing the spontaneous closure of ventricular septal
... Ventricular septal defect (VSD) is the most common congenital heart defect, which accounts for 20%-42.86% of all congenital heart diseases (CHD) [1-3]. The incidence of VSD is approximately 1.35 to 17.3 per 1000 live births [4, 5]. Some of these defects can close spontaneously, or diminish without s ...
... Ventricular septal defect (VSD) is the most common congenital heart defect, which accounts for 20%-42.86% of all congenital heart diseases (CHD) [1-3]. The incidence of VSD is approximately 1.35 to 17.3 per 1000 live births [4, 5]. Some of these defects can close spontaneously, or diminish without s ...
Clinical recommendations for cardiopulmonary exercise testing data
... Several CPX statements have been published by well-respected organizations in both the US and Europe.1 – 5 Despite these prominent reports and the plethora of pertinent medical literature which they feature, underutilization of CPX persists. This discrepancy is at least partly attributable to the fa ...
... Several CPX statements have been published by well-respected organizations in both the US and Europe.1 – 5 Despite these prominent reports and the plethora of pertinent medical literature which they feature, underutilization of CPX persists. This discrepancy is at least partly attributable to the fa ...
Assessment of Myocardial Fibrosis With Cardiovascular Magnetic
... and the ejection fraction was significantly related to the transmural extent of LGE (46). During the chronic phase of infarction, when a dense fibrotic scar replaces the infarcted myocardium, Mahrholdt et al. (17) showed the accuracy and the clinical reproducibility of delayed enhancement for infarc ...
... and the ejection fraction was significantly related to the transmural extent of LGE (46). During the chronic phase of infarction, when a dense fibrotic scar replaces the infarcted myocardium, Mahrholdt et al. (17) showed the accuracy and the clinical reproducibility of delayed enhancement for infarc ...
Repolarization Changes Underlying Long
... conclusions, both regarding the spatial pattern of repolarization changes in cardiac memory and the underlying mechanisms. The present study was undertaken to produce 3-dimensional images of the repolarization changes underlying long-term cardiac memory in humans. Methods and Results—Nine adult subj ...
... conclusions, both regarding the spatial pattern of repolarization changes in cardiac memory and the underlying mechanisms. The present study was undertaken to produce 3-dimensional images of the repolarization changes underlying long-term cardiac memory in humans. Methods and Results—Nine adult subj ...
Association between collagen cross
... with furazolidone induced dilated cardiomyopathy (DCM). Methods and results: Forty 2-week-old Sprague-Dawlay (SD) rats were used, 30 rats were treated with furazolidone (0.15 mg/body weight (g)/day per gavage for 8 weeks, FZ group), 10 rats were treated by equal volume water daily per gavage for 8 w ...
... with furazolidone induced dilated cardiomyopathy (DCM). Methods and results: Forty 2-week-old Sprague-Dawlay (SD) rats were used, 30 rats were treated with furazolidone (0.15 mg/body weight (g)/day per gavage for 8 weeks, FZ group), 10 rats were treated by equal volume water daily per gavage for 8 w ...
Nonsurgical closure of secundum atrial septal defect and patent
... increase of the right atrial pressure such as in chronic obstructive lung disease and after pulmonary embolism. The shunt volume depends on PFO size, duration of atrial systole and the pressure difference between the two atria. Left-to-right shunting is usually prevented by complete closure of the P ...
... increase of the right atrial pressure such as in chronic obstructive lung disease and after pulmonary embolism. The shunt volume depends on PFO size, duration of atrial systole and the pressure difference between the two atria. Left-to-right shunting is usually prevented by complete closure of the P ...
anomalous pulmonary venous drainage - Heart
... into which they drain, and the secondary effects that this re-circulation of blood in the pulmonary circuit has upon the size and shape of the heart. Whether or not there is an associated atrial septal defect there is a continuous left-to-right shunt of blood, the effect of this being to cause right ...
... into which they drain, and the secondary effects that this re-circulation of blood in the pulmonary circuit has upon the size and shape of the heart. Whether or not there is an associated atrial septal defect there is a continuous left-to-right shunt of blood, the effect of this being to cause right ...
Right Ventricular Dilatation on Bedside Echocardiography
... (moderate to high pretest probability) or confirmed pulmonary embolism. Participants had bedside echocardiography evaluating for right ventricular dilatation (defined as right ventricular to left ventricular ratio greater than 1:1) and right ventricular dysfunction (right ventricular hypokinesis, para ...
... (moderate to high pretest probability) or confirmed pulmonary embolism. Participants had bedside echocardiography evaluating for right ventricular dilatation (defined as right ventricular to left ventricular ratio greater than 1:1) and right ventricular dysfunction (right ventricular hypokinesis, para ...
Noninvasive Evaluation of Myocardial Ischemia and Left
... deaths reported had circulatory disease as the underlying cause of death [1] despite advances in medical, interventional and surgical treatments. A century ago the same figure was around 10 %, infectious diseases and malnutrition at that time being the most common causes of death. Although still the ...
... deaths reported had circulatory disease as the underlying cause of death [1] despite advances in medical, interventional and surgical treatments. A century ago the same figure was around 10 %, infectious diseases and malnutrition at that time being the most common causes of death. Although still the ...
Diastolic Heart Failure and Critical Illness
... are not yet widely used in the cardiologic literature [8]. They separated three sequential steps for the diagnosis: (1) diagnosis of CHF, (2) preserved systolic LV function (LVEF > 50%), (3) documentation of LV diastolic dysfunction if feasible. Accordingly, the authors proposed to classify subjects ...
... are not yet widely used in the cardiologic literature [8]. They separated three sequential steps for the diagnosis: (1) diagnosis of CHF, (2) preserved systolic LV function (LVEF > 50%), (3) documentation of LV diastolic dysfunction if feasible. Accordingly, the authors proposed to classify subjects ...
Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in
... the left ventricular outflow tract (Video SV1 in the online-only Data Supplement; legend for SV1 is included in the onlineonly Data Supplement). The prevalence of moderate or severe AR, assessed using color Doppler echocardiography, was 70%, 81%, and 73% in Wave mice at 1.5, 6, and 12 months of age, ...
... the left ventricular outflow tract (Video SV1 in the online-only Data Supplement; legend for SV1 is included in the onlineonly Data Supplement). The prevalence of moderate or severe AR, assessed using color Doppler echocardiography, was 70%, 81%, and 73% in Wave mice at 1.5, 6, and 12 months of age, ...
Point mutations in murine Nkx2-5 phenocopy human
... and Supplemental Figure 2), presented as right ventricle and right atrial dilation and misalignment in relation to the left ventricle. Furthermore, Nkx2-5183P/+ mice also displayed increased trabecular layers on the left ventricular wall, indicative of left ventricular noncompaction, commonly observ ...
... and Supplemental Figure 2), presented as right ventricle and right atrial dilation and misalignment in relation to the left ventricle. Furthermore, Nkx2-5183P/+ mice also displayed increased trabecular layers on the left ventricular wall, indicative of left ventricular noncompaction, commonly observ ...
The Sequence of Normal Recovery of Excitability in the
... an inverse relation to the order of normal ventricular excitation.'2 Endocardial refractory periods exceeded those at epicardial sites. Apical refractory periods were longer than those at the ventricular base and the left side of the interveiitricular septum had longer refractory periods than those ...
... an inverse relation to the order of normal ventricular excitation.'2 Endocardial refractory periods exceeded those at epicardial sites. Apical refractory periods were longer than those at the ventricular base and the left side of the interveiitricular septum had longer refractory periods than those ...
Usefulness of the 12-lead electrocardiogram in the follow
... coronary vein, biventricular (BIV) pacing with LV from a posterior or posterolateral coronary vein + RV from the apex or BIV pacing with LV from a posterior or posterolateral coronary vein + RV from the septal/outflow tract. (1) Monochamber RV pacing. During septal or RV outflow tract (RVOT) pacing ...
... coronary vein, biventricular (BIV) pacing with LV from a posterior or posterolateral coronary vein + RV from the apex or BIV pacing with LV from a posterior or posterolateral coronary vein + RV from the septal/outflow tract. (1) Monochamber RV pacing. During septal or RV outflow tract (RVOT) pacing ...
THE UTILITY OF PULSE PRESSURE MEASURED BY RADIAL
... this must be considered when we compare the two measures. PPb is associated with increased left ventricular mass18. This may be due to the fact that higher pulse pressures in the proximal arterial tree places increased workload on the heart. The heart muscle hypertrophies to compensate for this incr ...
... this must be considered when we compare the two measures. PPb is associated with increased left ventricular mass18. This may be due to the fact that higher pulse pressures in the proximal arterial tree places increased workload on the heart. The heart muscle hypertrophies to compensate for this incr ...
Sleep, dreams, and sudden death: the case for
... induced arrhythmias. Stimulation of this structure increased ten-fold the incidence of ventricular fibrillation elicited experimentally by occlusion of the coronary artery [17]. This enhanced vulnerability was linked to increased sympathetic activity, because beta-adrenergic receptor blockade but no ...
... induced arrhythmias. Stimulation of this structure increased ten-fold the incidence of ventricular fibrillation elicited experimentally by occlusion of the coronary artery [17]. This enhanced vulnerability was linked to increased sympathetic activity, because beta-adrenergic receptor blockade but no ...
Evaluation of the CO2 Rebreathing Cardiac Output
... cardiography, echocardiography, and ballistocardiography.-1 Methods such as these have first had to establish the soundness of the principles involved in measuring cardiac output, and then to demonstrate that results obtained from the given technique are comparable to those of standard invasive meth ...
... cardiography, echocardiography, and ballistocardiography.-1 Methods such as these have first had to establish the soundness of the principles involved in measuring cardiac output, and then to demonstrate that results obtained from the given technique are comparable to those of standard invasive meth ...
Contemporary Pacemakers - CCM, University of Pittsburgh
... bradycardia, often after termination of an atrial tachyarrhythmia. In some cases, sinus node disease manifests as inadequate change in heart rate in response to physiologic stress, such as exercise. Although most commonly caused by idiopathic degeneration and fibrosis of the sinoatrial node, sinus n ...
... bradycardia, often after termination of an atrial tachyarrhythmia. In some cases, sinus node disease manifests as inadequate change in heart rate in response to physiologic stress, such as exercise. Although most commonly caused by idiopathic degeneration and fibrosis of the sinoatrial node, sinus n ...
chronic congestive heart failure.
... Physiological studies of experimental animals. left ventricles of normal dogs. Myosin from sepaThe results are presented in Table I. The 11 dogs rate right and left ventricles of dogs with right with tricuspid insufficiency and pulmonic stenosis heart failure secondary to tricuspid insufficiency sho ...
... Physiological studies of experimental animals. left ventricles of normal dogs. Myosin from sepaThe results are presented in Table I. The 11 dogs rate right and left ventricles of dogs with right with tricuspid insufficiency and pulmonic stenosis heart failure secondary to tricuspid insufficiency sho ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.