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Metagenomic Analysis Using MEGAN4
Metagenomic Analysis Using MEGAN4

Types of variation in DNA-A among isolates of East African cassava
Types of variation in DNA-A among isolates of East African cassava

Notes
Notes

... There is a famous theorem of Cayley that says that the number of trees on a set with n elements is nn−2 for each n ≥ 1. This theorem has many proofs; one is given below. Sometimes it is useful to consider a graph with a particular vertex that may be used as a starting point. A rooted graph is a pair ...
An Empirical Test for Branch-Specific Positive Selection
An Empirical Test for Branch-Specific Positive Selection

Molecular evidence for the existence of additional members of the
Molecular evidence for the existence of additional members of the

Origin of the eukaryotic cell
Origin of the eukaryotic cell

Genetic Inversion: Relationships Among Species
Genetic Inversion: Relationships Among Species

Aggregating Multiple Instances in Relational Database Using Semi-Supervised Genetic Algorithm-based Clustering Technique
Aggregating Multiple Instances in Relational Database Using Semi-Supervised Genetic Algorithm-based Clustering Technique

...  Step 3) For each encoded term, add this term to the bag of terms that describes the characteristics of a record associated with them. The encoding processes transform relational datasets into data represented in a vectorspace model [9], had been implemented in DARA [7,8]. Given this data represent ...
pdf
pdf

Applied and Environmental Microbiology
Applied and Environmental Microbiology

Clustering Using Objective Functions and Stochastic
Clustering Using Objective Functions and Stochastic

... correlated, which allows for parsimonious representation of the cluster means through the use of penalized splines. One might argue that the methods proposed in this paper are computationally burdensome relative to more conventional clustering algorithms because of the requirement of a stochastic se ...
pdf
pdf

... sequences unrelated to most known species. Indeed, matches for these particular regions were only present amongst the magical taxa themselves, establishing this group as a new clade. But as we were using an abundantly widespread taxon-rich analyses, we discovered that this new clade is part of a mon ...
Optimal Conditioning of Quasi-Newton Methods
Optimal Conditioning of Quasi-Newton Methods

... IV. Computational Results. The five methods for selecting t discussed in Section III were tested on the four test problems documented in [6]. As previous testing included the straight Fletcher-Powell and Barnes-Rosen [1], [5] techniques, they are not included here. Previous tests have shown both to ...
Application of rpoB sequence similarity analysis, REP‐PCR and
Application of rpoB sequence similarity analysis, REP‐PCR and

... gene. The same difference was designated by Zeigler (2005) during comparison of 16S rRNA and recN deriving phylogenies because of the mutational saturation of the later gene. Although bootstrap values were lower for the rpoB tree, both phylogenetic analyses shared satisfactory bootstrap support. In ...
Chapter 4 Methods
Chapter 4 Methods

pdf
pdf

Fault Tolerant Reachability for Directed Graphs
Fault Tolerant Reachability for Directed Graphs

The Problem of Missing Values in Decision Tree Grafting
The Problem of Missing Values in Decision Tree Grafting

Gentile, Margaret: Computational Methods for the Design of PCR Primers for the Amplification of functional Markers from Environmental Samples
Gentile, Margaret: Computational Methods for the Design of PCR Primers for the Amplification of functional Markers from Environmental Samples

... is often used as an input for a primer design program, because the researcher requires a primer that will work under specified reaction conditions. The melting temperature is also important for applications with greater than one primer, because primers with different melting temperatures will have d ...
ppt
ppt

2. Estimating θ - UNC Computational Genetics
2. Estimating θ - UNC Computational Genetics

... 3. Estimating ρ • Estimating ρ is hard, both statistically and computationally. – Using infinite side model, all mutation events can be listed whereas all recombination events cannot. A recombination can only be inferred with certainty if all four gametes are present. – The number of possible genea ...
The influence of geological events on the
The influence of geological events on the

... the second, we hypothesized more recent diversification of the two species as a result of the repeated isolation of populations in various glacial refugia during the Pleistocene (Appendix S2, H1 and H2). The two models were tested using diyabc, and summary statistics were calculated for mtDNA and nD ...
Document
Document

q-gram Based Database Searching Using a Suffix Array (QUASAR)
q-gram Based Database Searching Using a Suffix Array (QUASAR)

... Only few attempts have been made to adapt these techniques to the similarity searches needed for biological purposes. Martinez Mar83], for example, gave the rst application of a position tree in molecular biology. This data structure requires about 16 times the space needed to store the original d ...
Hidden Markov Models
Hidden Markov Models

... Decoding problem is now reduced to finding a longest path in the directed acyclic graph ( DAG)  The length of path is defined as product of its edges weights instead of caluculating sum of weights in dynamic programming algorithms.  Application of logarithms to the solution makes the same as to p ...
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Computational phylogenetics

Computational phylogenetics is the application of computational algorithms, methods, and programs to phylogenetic analyses. The goal is to assemble a phylogenetic tree representing a hypothesis about the evolutionary ancestry of a set of genes, species, or other taxa. For example, these techniques have been used to explore the family tree of hominid species and the relationships between specific genes shared by many types of organisms. Traditional phylogenetics relies on morphological data obtained by measuring and quantifying the phenotypic properties of representative organisms, while the more recent field of molecular phylogenetics uses nucleotide sequences encoding genes or amino acid sequences encoding proteins as the basis for classification. Many forms of molecular phylogenetics are closely related to and make extensive use of sequence alignment in constructing and refining phylogenetic trees, which are used to classify the evolutionary relationships between homologous genes represented in the genomes of divergent species. The phylogenetic trees constructed by computational methods are unlikely to perfectly reproduce the evolutionary tree that represents the historical relationships between the species being analyzed. The historical species tree may also differ from the historical tree of an individual homologous gene shared by those species.Producing a phylogenetic tree requires a measure of homology among the characteristics shared by the taxa being compared. In morphological studies, this requires explicit decisions about which physical characteristics to measure and how to use them to encode distinct states corresponding to the input taxa. In molecular studies, a primary problem is in producing a multiple sequence alignment (MSA) between the genes or amino acid sequences of interest. Progressive sequence alignment methods produce a phylogenetic tree by necessity because they incorporate new sequences into the calculated alignment in order of genetic distance.
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