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Evolution of the Actin Gene Family in Testate Lobose Amoebae
Evolution of the Actin Gene Family in Testate Lobose Amoebae

... are the subject of this study. Most knowledge in this group stems from studies in the model slime molds (Dictyostelium and Physarum) and some pathogenic lineages (Entamoeba and Acanthamoeba). The completed genome of D. discoideum (Eichinger et al. 2005) reveals a 41-member set of actin paralogs enco ...
Python Programming: An Introduction to Computer - comp
Python Programming: An Introduction to Computer - comp

Hybridization, polyploidy, and evolutionary transitions between
Hybridization, polyploidy, and evolutionary transitions between

Footnotes to the flowchart
Footnotes to the flowchart

... 12. Has the EQA-organizer registered the correct method and result? NO (E): Ask for a new corrected report from the EQA-organizer. 13. Has the laboratory reported the correct method and result? NO (I): The internal routines have to be reevaluated. 14. Have the samples been sent in a proper way? NO ( ...
Numerical Methods in Engineering with Python 3
Numerical Methods in Engineering with Python 3

... on Python programming. We introduce just enough Python to implement the numerical algorithms. That leaves the vast majority of the language unexplored. Most engineers are not programmers, but problem solvers. They want to know what methods can be applied to a given problem, what their strengths and ...
Use of Taxonomy in Risk Assessment of Micro
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R u t c o r Research Solution of an optimal reservoir
R u t c o r Research Solution of an optimal reservoir

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Chapter Outline

... and protein sequences show the evolutionary and protein sequences show the evolutionary  relationships among organisms. • The rate of molecular evolution can be determined by  calculating the average number of amino acid or  nucleotide changes that have occurred per site in a  molecule since two or  ...
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L10: k-Means Clustering
L10: k-Means Clustering

... k = O(n )) number of possible distinct cluster centers. But it could be exponential in k and d (the dimension when Euclidean distance used). • However, usually R = 10 is fine. • Smoothed analysis: if data perturbed randomly slightly, then R = O(n35 k 34 d8 ). This is “polynomial,” but still ridiculo ...
Graph-based consensus clustering for class discovery from gene
Graph-based consensus clustering for class discovery from gene

... attention to class discovery based on the consensus clustering approaches. • They consist of two major steps: – Generating a cluster ensemble based on a clustering algorithm. – Finding a consensus partition based on this ensemble. ...
Homology modeling workshop
Homology modeling workshop

... of DNA to complex molecular machines like the ribosome. • There are currently 57013 structures deposited in the PDB. However, taking out redundant sequences (e.g. 90%) reduces the number of structures to 19988… • Each structure receives a unique 4 letter ID ...
Evolution of Behavior: Phylogeny and the Origin of Present
Evolution of Behavior: Phylogeny and the Origin of Present

... rat, pigeon, primate) to investigate the neurological or developmental pathways of behavior or to identify universal cognitive processes, such as those involved in learning. As is already becoming evident in this chapter, phylogenetic comparative biologists typically examine phenotypic variation in ...
Lecture 3 — October 16th 3.1 K-means
Lecture 3 — October 16th 3.1 K-means

IOSR Journal of Computer Engineering (IOSR-JCE)
IOSR Journal of Computer Engineering (IOSR-JCE)

... Clustering is the task of partitioning the given unlabeled dataset into a number of groups such that objects in the same group are similar to each other and dissimilar to the objects in the other groups. The dissimilarities are assessed based on the attribute Values representing the objects. Althoug ...
CoevolPaper2 - University of Illinois Archives
CoevolPaper2 - University of Illinois Archives

... Due to the crystallization procedure, a combination of effects such as different conformational states, difference in crystallization conditions, and/or the lower resolution structures, can lead to noise in the structural phylogenetic analysis. As a result, sequence-based phylogenetic methods yield ...
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Intro2007f

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Optimization_2016_JS

... What is optimization? • Optimization = Finding the best way of doing something • The overall problem usually consists of a multitude of decisions that are made simultaneously (decision variables) • The “goodness” of a certain set of decisions is measured by a numerical value called the objective fu ...
ICDM07_Jin - Kent State University
ICDM07_Jin - Kent State University

... discretization algorithms: Yang and Webb; Kurgan and Cios (CAIM); Boulle (Khiops). • CAIM attempts to minimize the number of discretization intervals and at the same time to minimize the information loss. • Khiops uses Pearson’s X2 statistic to select merging consecutive intervals that minimize the ...
Data Discretization
Data Discretization

... discretization algorithms: Yang and Webb; Kurgan and Cios (CAIM); Boulle (Khiops). • CAIM attempts to minimize the number of discretization intervals and at the same time to minimize the information loss. • Khiops uses Pearson’s X2 statistic to select merging consecutive intervals that minimize the ...
Cophylogeny and disparate rates of evolution in sympatric lineages
Cophylogeny and disparate rates of evolution in sympatric lineages

... nies for the hosts and their associates, a pattern termed cophylogeny. Testing for cophylogeny is the first step toward understanding codivergence, cospeciation, coadaptation, and general ecological relationships between associated taxa. Whereas some studies have found statistically significant cophyl ...
Technical Article Recent Developments in Discontinuous Galerkin Methods for the Time–
Technical Article Recent Developments in Discontinuous Galerkin Methods for the Time–

... The origins of DG methods can be traced back to the seventies, where they were proposed for the numerical solution of the neutron transport equation, as well as for the weak enforcement of continuity in Galerkin methods for elliptic and parabolic problems; see [1] for a historical review. In the mea ...
Male-Biased Mutation Rate and Divergence in Autosomal, Z
Male-Biased Mutation Rate and Divergence in Autosomal, Z

... 1997), with the Tamura-Nei (Tamura and Nei 1993) model of sequence evolution. Distances were estimated on the assumption that all sites evolve at the same rate (i.e., no among-site rate variation). The estimation of confidence intervals and hypothesis testing was carried out by application of nonpar ...
Mitochondrial genes in the colourless alga Prototheca wickerhamii
Mitochondrial genes in the colourless alga Prototheca wickerhamii

Inference IV: Approximate Inference
Inference IV: Approximate Inference

... practice, EM converges rather quickly at start but converges slowly near the (possibly-local) maximum.  Hence, often EM is used few iterations and then Gradient Ascent steps are applied. ...
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Computational phylogenetics

Computational phylogenetics is the application of computational algorithms, methods, and programs to phylogenetic analyses. The goal is to assemble a phylogenetic tree representing a hypothesis about the evolutionary ancestry of a set of genes, species, or other taxa. For example, these techniques have been used to explore the family tree of hominid species and the relationships between specific genes shared by many types of organisms. Traditional phylogenetics relies on morphological data obtained by measuring and quantifying the phenotypic properties of representative organisms, while the more recent field of molecular phylogenetics uses nucleotide sequences encoding genes or amino acid sequences encoding proteins as the basis for classification. Many forms of molecular phylogenetics are closely related to and make extensive use of sequence alignment in constructing and refining phylogenetic trees, which are used to classify the evolutionary relationships between homologous genes represented in the genomes of divergent species. The phylogenetic trees constructed by computational methods are unlikely to perfectly reproduce the evolutionary tree that represents the historical relationships between the species being analyzed. The historical species tree may also differ from the historical tree of an individual homologous gene shared by those species.Producing a phylogenetic tree requires a measure of homology among the characteristics shared by the taxa being compared. In morphological studies, this requires explicit decisions about which physical characteristics to measure and how to use them to encode distinct states corresponding to the input taxa. In molecular studies, a primary problem is in producing a multiple sequence alignment (MSA) between the genes or amino acid sequences of interest. Progressive sequence alignment methods produce a phylogenetic tree by necessity because they incorporate new sequences into the calculated alignment in order of genetic distance.
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