Local functions for FMRP in axon growth cone motility and activity
... to be an increase in total spine density in vivo (Irwin et al., 2002); however, this phenotype was only transient during postnatal development in a subsequent study (Nimchinsky et al., 2001). The spine phenotype in FXS may be due to altered translational regulation needed for spine development and m ...
... to be an increase in total spine density in vivo (Irwin et al., 2002); however, this phenotype was only transient during postnatal development in a subsequent study (Nimchinsky et al., 2001). The spine phenotype in FXS may be due to altered translational regulation needed for spine development and m ...
The time course of selective visual attention: theory and experiments
... One can distinguish between standard and triple conjunction search. In the standard conjunction search condition, there are two distractor groups, each having two features, and the target shares one feature with each distractor group. In a triple conjunction search the target may differ from all dist ...
... One can distinguish between standard and triple conjunction search. In the standard conjunction search condition, there are two distractor groups, each having two features, and the target shares one feature with each distractor group. In a triple conjunction search the target may differ from all dist ...
166 - UCSF Physiology - University of California, San Francisco
... with the cell-sparse layer I positioned closest to the pial surface material). Western blot analysis further confirmed the loss of 1 (Fig. 2a,c). In mutant animals, however, no distinct cortical layers integrin protein from the cerebral cortex and hippocampus (Fig. were obvious except for layer I, ...
... with the cell-sparse layer I positioned closest to the pial surface material). Western blot analysis further confirmed the loss of 1 (Fig. 2a,c). In mutant animals, however, no distinct cortical layers integrin protein from the cerebral cortex and hippocampus (Fig. were obvious except for layer I, ...
Clarke`s column neurons as the focus of a corticospinal corollary circuit
... provide anatomical evidence that a subset of Clarke’s column dSC neurons in receipt of proprioceptive sensory input are also contacted by the terminals of corticospinal neurons. To assess the function of these corticospinal inputs, we analyzed the response of fluorogold-labeled Clarke’s column dSC n ...
... provide anatomical evidence that a subset of Clarke’s column dSC neurons in receipt of proprioceptive sensory input are also contacted by the terminals of corticospinal neurons. To assess the function of these corticospinal inputs, we analyzed the response of fluorogold-labeled Clarke’s column dSC n ...
Volumetric Two-photon Imaging of Neurons Using
... Two-photon excitation laser scanning microscopy (TPM) [1] enables high spatial resolution optical imaging in highly scattering tissue such as the mammalian brain. When combined with geneticallyencoded calcium indicators [2, 3], or synthetic indicators that label neural populations [4], intracellular ...
... Two-photon excitation laser scanning microscopy (TPM) [1] enables high spatial resolution optical imaging in highly scattering tissue such as the mammalian brain. When combined with geneticallyencoded calcium indicators [2, 3], or synthetic indicators that label neural populations [4], intracellular ...
Extraction of Sensory Parameters from a Neural Map by Primary
... cricket, Acheta domestica, showing the location of the abdominal nerve cord. The cerci are two abdominal appendages projecting from the rear of the animal’s body. Both cerci are covered with mechanosensory hairs, each of which is innervated with a single sensory neuron. The axons of the sensory neur ...
... cricket, Acheta domestica, showing the location of the abdominal nerve cord. The cerci are two abdominal appendages projecting from the rear of the animal’s body. Both cerci are covered with mechanosensory hairs, each of which is innervated with a single sensory neuron. The axons of the sensory neur ...
The Structure of Pairwise Correlation in Mouse Primary Visual
... Throughout sensory systems, neurons are organized by response preference, so that like-responding neurons are close to each other, creating a functional map [e.g., orientation pinwheels in primary visual cortex (V1)]. Despite the ubiquity of maps, their role is unclear. For example, although rodent ...
... Throughout sensory systems, neurons are organized by response preference, so that like-responding neurons are close to each other, creating a functional map [e.g., orientation pinwheels in primary visual cortex (V1)]. Despite the ubiquity of maps, their role is unclear. For example, although rodent ...
Neuropathological Alterations in Alzheimer Disease
... Dense-core plaques: fibrillar amyloid deposits with compact core that stains with Thioflavin-S and Congo Red. Dense-core plaques are typically surrounded by dystrophic neurites (neuritic plaques), reactive astrocytes and activated microglial cells, and associated with synaptic loss. A semiquantitati ...
... Dense-core plaques: fibrillar amyloid deposits with compact core that stains with Thioflavin-S and Congo Red. Dense-core plaques are typically surrounded by dystrophic neurites (neuritic plaques), reactive astrocytes and activated microglial cells, and associated with synaptic loss. A semiquantitati ...
This article was originally published in the
... read the word and the instructed task of naming the color in which the word is printed (Figure 2(a)). When the word and the color are incongruent, these two responses conflict with each other. Conflict signals may trigger an executive control function that initiates increased effort to improve perfo ...
... read the word and the instructed task of naming the color in which the word is printed (Figure 2(a)). When the word and the color are incongruent, these two responses conflict with each other. Conflict signals may trigger an executive control function that initiates increased effort to improve perfo ...
Inhibitory Plasticity Balances Excitation and Inhibition in Sensory
... in response to natural stimuli and fits well with a recently observed interaction of excitatory and inhibitory receptive field plasticity. The introduction of inhibitory plasticity in suitable recurrent networks provides a homeostatic mechanism that leads to asynchronous irregular network states. Fu ...
... in response to natural stimuli and fits well with a recently observed interaction of excitatory and inhibitory receptive field plasticity. The introduction of inhibitory plasticity in suitable recurrent networks provides a homeostatic mechanism that leads to asynchronous irregular network states. Fu ...
Regions of the Brain
... Types of Reflexes and Regulation Patellar, or knee-jerk, reflex is an example of a two-neuron reflex arc ...
... Types of Reflexes and Regulation Patellar, or knee-jerk, reflex is an example of a two-neuron reflex arc ...
Vagal Input to Lateral Area 3a in Cat Cortex
... in rats receives input from vagal afferents (Ito 2002). This provided the first anatomically identified demonstration of this putative visceral region in experimental animals. The results suggested that this region is continuous with the intraoral trigeminal representation in S1. However, these resu ...
... in rats receives input from vagal afferents (Ito 2002). This provided the first anatomically identified demonstration of this putative visceral region in experimental animals. The results suggested that this region is continuous with the intraoral trigeminal representation in S1. However, these resu ...
Effect of PACAP in Central and Peripheral Nerve Injuries
... presence of PACAP and PAC1 receptor mRNA are well described, suggesting important function of this peptide in these brain regions [31,32]. PACAP mRNA is expressed in alternating layers (I, III, and V layer) of the cerebral cortex, and it is localized to the CA1 and CA4 subregions of the hippocampus ...
... presence of PACAP and PAC1 receptor mRNA are well described, suggesting important function of this peptide in these brain regions [31,32]. PACAP mRNA is expressed in alternating layers (I, III, and V layer) of the cerebral cortex, and it is localized to the CA1 and CA4 subregions of the hippocampus ...
Hemispheric asymmetries of cortical volume in the human brain
... 0010-9452/$ e see front matter ª 2011 Elsevier Ltd. All rights reserved. doi:10.1016/j.cortex.2011.11.002 ...
... 0010-9452/$ e see front matter ª 2011 Elsevier Ltd. All rights reserved. doi:10.1016/j.cortex.2011.11.002 ...
521 THE CHOLINERGIC LIMBIC SYSTEM: PROJECTIONS TO
... is aggregated at the base of the pyramidal cell layer, i.e. in the region of the basal pyramidal dendrites, and extends between the bodies of the pyramidal cells. The staining is far heavier in area CA3 than in other hippocampal areas. Enzyme is also found in the stratum radiatum in the region of th ...
... is aggregated at the base of the pyramidal cell layer, i.e. in the region of the basal pyramidal dendrites, and extends between the bodies of the pyramidal cells. The staining is far heavier in area CA3 than in other hippocampal areas. Enzyme is also found in the stratum radiatum in the region of th ...
Three-dimensional auditory localization in the
... paradigm. (b) Behavioral performances of big brown bats in the distance discrimination task. Bats show very similar behavioral performances when tested with real objects placed at difference distances and with virtual targets simulating the time-delay differences between the real objects. (c) Behavi ...
... paradigm. (b) Behavioral performances of big brown bats in the distance discrimination task. Bats show very similar behavioral performances when tested with real objects placed at difference distances and with virtual targets simulating the time-delay differences between the real objects. (c) Behavi ...
Document
... BIN1 antibodies (pAb BSH3, mAb 2F11, and mAb 99D) and markers of AD pathology. Figures A and B show the distribution and density of senile plaques and neurofibrillary tangles in the entorhinal cortex of a patient with AD [immunostained using antibodies against Aβ (mAb 4G8) and Tau (Tau-2)], in relat ...
... BIN1 antibodies (pAb BSH3, mAb 2F11, and mAb 99D) and markers of AD pathology. Figures A and B show the distribution and density of senile plaques and neurofibrillary tangles in the entorhinal cortex of a patient with AD [immunostained using antibodies against Aβ (mAb 4G8) and Tau (Tau-2)], in relat ...
Aberrant Resting-State Functional Connectivity in the
... autonomic, endocrine, and immune adjustments, and its initiation depends upon higher brain functions for the interpretation of sensory information and situations that threaten homeostasis [20]. Resting-state functional brain magnetic resonance imaging (rfMRI) is a powerful tool to characterize brain ...
... autonomic, endocrine, and immune adjustments, and its initiation depends upon higher brain functions for the interpretation of sensory information and situations that threaten homeostasis [20]. Resting-state functional brain magnetic resonance imaging (rfMRI) is a powerful tool to characterize brain ...
Feedforward and feedback inhibition in neostriatal GABAergic spiny
... presynaptic convergence and divergence and the net effect of the activation of each circuit on the postsynaptic activity of the spiny neuron. These data have revealed that the feedforward inhibition is powerful and widespread, with spiking in a single interneuron being capable of significantly delay ...
... presynaptic convergence and divergence and the net effect of the activation of each circuit on the postsynaptic activity of the spiny neuron. These data have revealed that the feedforward inhibition is powerful and widespread, with spiking in a single interneuron being capable of significantly delay ...
The Wick in the Candle of Learning
... finding led to a behavioral study, which showed that subjects spent more scarce resources (either limited tokens or waiting time) to find out answers when they were more curious. The functional imaging also showed that curiosity increased activity in memory areas when subjects guessed incorrectly, w ...
... finding led to a behavioral study, which showed that subjects spent more scarce resources (either limited tokens or waiting time) to find out answers when they were more curious. The functional imaging also showed that curiosity increased activity in memory areas when subjects guessed incorrectly, w ...
gross_neuroanatomy-1
... surface of the brain. Unlike other sulci that delineate lobes, TO is much more variable between individuals and it is not easy to identify • The functional overlap between posterior temporal and occipital cortices is also reflected by the lack of one or more sulci that divide the temporal from the ...
... surface of the brain. Unlike other sulci that delineate lobes, TO is much more variable between individuals and it is not easy to identify • The functional overlap between posterior temporal and occipital cortices is also reflected by the lack of one or more sulci that divide the temporal from the ...
Evolutionarily conserved prefrontal-amygdalar dysfunction in early
... MJ Slattery2, RJ Davidson2,3,5,10,11, AS Fox2,3,4,5,10,11 and NH Kalin2,3,4,5,10 Some individuals are endowed with a biology that renders them more reactive to novelty and potential threat. When extreme, this anxious temperament (AT) confers elevated risk for the development of anxiety, depression a ...
... MJ Slattery2, RJ Davidson2,3,5,10,11, AS Fox2,3,4,5,10,11 and NH Kalin2,3,4,5,10 Some individuals are endowed with a biology that renders them more reactive to novelty and potential threat. When extreme, this anxious temperament (AT) confers elevated risk for the development of anxiety, depression a ...
BMC Neuroscience
... The second analysis addressed this question by considering the relationship of the structural type of pairs of connected cortices. This analysis was motivated by our previous findings that cortical type is highly correlated with the laminar pattern of ipsilateral corticocortical connections [15]. St ...
... The second analysis addressed this question by considering the relationship of the structural type of pairs of connected cortices. This analysis was motivated by our previous findings that cortical type is highly correlated with the laminar pattern of ipsilateral corticocortical connections [15]. St ...
Estrogenic influences in pain processing Linköping University Post Print
... thereby avoiding the need for high estrogen concentrations systemically, concentrations that could cause severe adverse effects on non-neural tissue (Cornil et al., 2006). The regulation of lordosis behavior (Micevych and Mermelstein, 2008) and signaling in the dorsal root ganglion (Chaban and Micev ...
... thereby avoiding the need for high estrogen concentrations systemically, concentrations that could cause severe adverse effects on non-neural tissue (Cornil et al., 2006). The regulation of lordosis behavior (Micevych and Mermelstein, 2008) and signaling in the dorsal root ganglion (Chaban and Micev ...
A Circuit for Detection of Interaural Time Differences in the Brain
... This both allowed measurement of spikes within the nucleus laminaris and obviated the difficulties of extracellular recordings in the nucleus laminaris. Action potentials from single neurons in the nucleus laminaris are masked by the overwhelming field potential termed the neurophonic (Sullivan and ...
... This both allowed measurement of spikes within the nucleus laminaris and obviated the difficulties of extracellular recordings in the nucleus laminaris. Action potentials from single neurons in the nucleus laminaris are masked by the overwhelming field potential termed the neurophonic (Sullivan and ...