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ORGANIZATION OF CORTICAL AFFERENTS TO THE FRONTAL
... in the monkey from the point of view of its electrophysiological features. As for other features, the presence of the movement-related neurons was defined (71) as active due to the occurrence of some sensory signals. ...
... in the monkey from the point of view of its electrophysiological features. As for other features, the presence of the movement-related neurons was defined (71) as active due to the occurrence of some sensory signals. ...
The endogenous molecular clock orchestrates the temporal
... use is commonly linked with the fed/fasted and active/inactive behaviors, these changes in storage and use are also aligned with the 24-h (circadian) light/dark cycles attributed to the rising and setting of the sun and feeding/activity behavior [16]. At the core of circadian rhythms is a mechanism ...
... use is commonly linked with the fed/fasted and active/inactive behaviors, these changes in storage and use are also aligned with the 24-h (circadian) light/dark cycles attributed to the rising and setting of the sun and feeding/activity behavior [16]. At the core of circadian rhythms is a mechanism ...
CUCURBIT[7]URIL HOST-GUEST COMPLEXES WITH DRUG MOLECULES CONTAINING ISOQUINOLINE GROUPS Julian Kwok by
... the polymethylene chain length is between six and ten carbons, or is replaced with a pxylyl group, the first CB[7] will bind over the central bridge, resulting in both of the polar portals forming ion-dipole interactions with both positively charged nitrogens. A second CB[7] binds to a terminal isoq ...
... the polymethylene chain length is between six and ten carbons, or is replaced with a pxylyl group, the first CB[7] will bind over the central bridge, resulting in both of the polar portals forming ion-dipole interactions with both positively charged nitrogens. A second CB[7] binds to a terminal isoq ...
PDF - Journal of Neuroscience
... Department of Neurosciences and 2Department of Pathology, University of California–San Diego, La Jolla, California 92093 ...
... Department of Neurosciences and 2Department of Pathology, University of California–San Diego, La Jolla, California 92093 ...
Implication of novel neurotransmitter systems in the regulation of
... results in a rhythmic discharge of the two gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), by the gonadotroph cells of the anterior pituitary. The gonadotrop hormones reach the gonads via the systemic circulation and stimulate their steroid hormone production and game ...
... results in a rhythmic discharge of the two gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), by the gonadotroph cells of the anterior pituitary. The gonadotrop hormones reach the gonads via the systemic circulation and stimulate their steroid hormone production and game ...
lipoprotein metabolism
... What are the lipids carried by CM? Where is CM formed? What is the source for lipids in CM? How does the CM release FFA? What is the fate of the FFA and Glycerol? Where is the LPL found? What are the components of Remnant CM? ...
... What are the lipids carried by CM? Where is CM formed? What is the source for lipids in CM? How does the CM release FFA? What is the fate of the FFA and Glycerol? Where is the LPL found? What are the components of Remnant CM? ...
Differential Temporal Storage Capacity in the Baseline Activity of
... above this line reflect the start and end times of the interval in which a significant difference persisted for ⬎100 ms. C: baseline activity during the selected 100-ms interval (800 –700 ms prior to array presentation) in each trial is shown as a function of the cumulative successful trial count. O ...
... above this line reflect the start and end times of the interval in which a significant difference persisted for ⬎100 ms. C: baseline activity during the selected 100-ms interval (800 –700 ms prior to array presentation) in each trial is shown as a function of the cumulative successful trial count. O ...
Projections of the median raphe nucleus in the rat
... nonillustrated cases. Patterns of labeling were very consistent across cases. The main difference among cases was relative density of labeling; that is, light to moderate with small injections or dense with large injections. ...
... nonillustrated cases. Patterns of labeling were very consistent across cases. The main difference among cases was relative density of labeling; that is, light to moderate with small injections or dense with large injections. ...
A Weighted and Directed Interareal Connectivity
... potentially unidirectional pathways, of which one-third (10% of the total) were shown to originate from corresponding locations within the connected cortical areas. The NFP make an important contribution to the connectivity profile of each area. These findings have important consequences for understan ...
... potentially unidirectional pathways, of which one-third (10% of the total) were shown to originate from corresponding locations within the connected cortical areas. The NFP make an important contribution to the connectivity profile of each area. These findings have important consequences for understan ...
Activity in the Lateral Prefrontal Cortex Reflects Multiple Steps of
... monkeys that performed a path-planning task that required multiple stepwise movements of a cursor within a maze to reach a goal. Figures 1A and 1C show the sequence and timing of events for each trial in our behavioral task. As the monkeys placed their wrists in neutral positions, a start display ap ...
... monkeys that performed a path-planning task that required multiple stepwise movements of a cursor within a maze to reach a goal. Figures 1A and 1C show the sequence and timing of events for each trial in our behavioral task. As the monkeys placed their wrists in neutral positions, a start display ap ...
the role of zinc in the pathogenesis and treatment of central nervous
... tions with postsynaptic receptors may occur. The well known process of zinc inhibition of NMDA receptors in synapses occurs through two mechanisms, voltage independent allosteric inhibition, which reduce ion cannel opening frequency, and voltage dependent inhibition by blocking open channels (21, 25 ...
... tions with postsynaptic receptors may occur. The well known process of zinc inhibition of NMDA receptors in synapses occurs through two mechanisms, voltage independent allosteric inhibition, which reduce ion cannel opening frequency, and voltage dependent inhibition by blocking open channels (21, 25 ...
ORGANIZATION OF NEUROPIL
... easily recognized with light microscopy, but are probably more heterogeneous than in plexiform neuropil. There is no good anatomical information concerning the existence of unpolarized synapses or syncytial interneuron bridges. Diffuse neuropil is characteristic of the more posterior central ganglia ...
... easily recognized with light microscopy, but are probably more heterogeneous than in plexiform neuropil. There is no good anatomical information concerning the existence of unpolarized synapses or syncytial interneuron bridges. Diffuse neuropil is characteristic of the more posterior central ganglia ...
Learning to represent reward structure: A key to adapting to complex
... strongly; the value of an input, ei , is given by V (ei ) = ri + ri+1 + 2 ri+2 + . . ., where rj refers to the numeric in transition at input ej and ␥ is the discount factor, where 0 ≤ ␥ ≤ 1. Even if the value function is defined as such, its actual value is unknown, and it is thus learned in the ...
... strongly; the value of an input, ei , is given by V (ei ) = ri + ri+1 + 2 ri+2 + . . ., where rj refers to the numeric in transition at input ej and ␥ is the discount factor, where 0 ≤ ␥ ≤ 1. Even if the value function is defined as such, its actual value is unknown, and it is thus learned in the ...
Structure and Function in the Inferior Olivary Nucleus
... The inferior olivary nucleus is the source of the climbing fibres, one of the two major afferent pathways into the cerebellum. This thesis is concerned with aspects of the cellular anat ...
... The inferior olivary nucleus is the source of the climbing fibres, one of the two major afferent pathways into the cerebellum. This thesis is concerned with aspects of the cellular anat ...
Current Opinion in Neurobiology (2004)
... basis of expectancies of emotionally significant events. Recent human imaging studies support this claim [53]. On the other hand, the anatomical relations among the OFC and sensory regions (discussed later) are consistent with an important role for the OFC’s use of information from a variety of sens ...
... basis of expectancies of emotionally significant events. Recent human imaging studies support this claim [53]. On the other hand, the anatomical relations among the OFC and sensory regions (discussed later) are consistent with an important role for the OFC’s use of information from a variety of sens ...
Saccadic Eye Movements Modulate Visual Responses in the Lateral
... neurons. Some cells were not affected by eye movements, while others showed dramatic changes just after eye movements. We first asked whether this tendency was related to cell type. The LGN contains at least two processing streams: the parvocellular system, whose neurons have small receptive fields ...
... neurons. Some cells were not affected by eye movements, while others showed dramatic changes just after eye movements. We first asked whether this tendency was related to cell type. The LGN contains at least two processing streams: the parvocellular system, whose neurons have small receptive fields ...
Disorders of the Cerebellum and Its Connections
... Although the principal physiologic importance of the cerebellum resides in its contributions to somatic motor control, evidence is accumulating that the cerebellum is also involved in a variety of nonmotor functions (see Chapter 8). If this involvement is functionally significant, one would expect e ...
... Although the principal physiologic importance of the cerebellum resides in its contributions to somatic motor control, evidence is accumulating that the cerebellum is also involved in a variety of nonmotor functions (see Chapter 8). If this involvement is functionally significant, one would expect e ...
1 - BrainMaster
... events are published monthly. Most recent popular textbooks in the neurosciences also provide ample coverage of basic principles of adult neurogenesis, a topic which just 20 or 30 years ago was considered tangential, controversial, or unimportant. The discovery that some populations of neurons conti ...
... events are published monthly. Most recent popular textbooks in the neurosciences also provide ample coverage of basic principles of adult neurogenesis, a topic which just 20 or 30 years ago was considered tangential, controversial, or unimportant. The discovery that some populations of neurons conti ...
Topographically Specific Hippocampal Projections Target Functionally Distinct Prefrontal Areas in the
... orbital areas. In addition, there were differences in the topography of afferent neurons projecting to medial when compared with orbital cortices. Labeled neurons innervating medial cortices were found mainly i n the CA1’ and CA1 fields rostrally, but originated in the subicular fields caudally. In ...
... orbital areas. In addition, there were differences in the topography of afferent neurons projecting to medial when compared with orbital cortices. Labeled neurons innervating medial cortices were found mainly i n the CA1’ and CA1 fields rostrally, but originated in the subicular fields caudally. In ...
Red cell pyruvate kinase deficiency: molecular and clinical aspects
... Red cell PK is allosterically activated by FBP and inhibited by ATP (Kahn & Marie, 1982; Wang et al, 2001). The allosteric regulation can be described according to the sequential model of Monod et al (1965) with Vmax unchanged either in T- or R-state (350 U/mg). Thus, either in the presence or in th ...
... Red cell PK is allosterically activated by FBP and inhibited by ATP (Kahn & Marie, 1982; Wang et al, 2001). The allosteric regulation can be described according to the sequential model of Monod et al (1965) with Vmax unchanged either in T- or R-state (350 U/mg). Thus, either in the presence or in th ...
Structure of Receptive Fields in Area 3b of Primary Somatosensory
... hemispheres using standard techniques (Phillips et al., 1988; Mountcastle et al., 1991). On each recording day, a multielectrode microdrive (Mountcastle et al., 1991) was loaded with seven quartz-coated platinum /tungsten (90/10) electrodes (diameter, 80 mm; tip diameter, 4 mm; and impedance, 1–5 MV ...
... hemispheres using standard techniques (Phillips et al., 1988; Mountcastle et al., 1991). On each recording day, a multielectrode microdrive (Mountcastle et al., 1991) was loaded with seven quartz-coated platinum /tungsten (90/10) electrodes (diameter, 80 mm; tip diameter, 4 mm; and impedance, 1–5 MV ...
Chapter 33 Nervous System
... A. It forms a visual image. B. It controls the muscles of the iris. C. It interprets light intensity and colors. D. It sends action potentials to the brain. ...
... A. It forms a visual image. B. It controls the muscles of the iris. C. It interprets light intensity and colors. D. It sends action potentials to the brain. ...
Dynamics and Synchronization of Motifs of Neuronal Populations in the Presence
... Along the history, a multitude of clinical studies involving brain damage show that some brain functions depend on the integrity of specific brain areas (Kolb and Whishaw, 1990; Sporns, 2010). This represents another rich field supporting the principle of segregation in the brain. Altogether, these ...
... Along the history, a multitude of clinical studies involving brain damage show that some brain functions depend on the integrity of specific brain areas (Kolb and Whishaw, 1990; Sporns, 2010). This represents another rich field supporting the principle of segregation in the brain. Altogether, these ...
The central nervous system.
... a few receptor types.168 Furthermore, olfactory receptor cells characterized by such a limited set of receptor types are distributed evenly all over the mucosa.169 Thus, if each set of evenly distributed sensory cells characterized by few receptor types were to be identical to one set of sensory cel ...
... a few receptor types.168 Furthermore, olfactory receptor cells characterized by such a limited set of receptor types are distributed evenly all over the mucosa.169 Thus, if each set of evenly distributed sensory cells characterized by few receptor types were to be identical to one set of sensory cel ...
Spontaneous activity in developing sensory circuits
... These data suggest that some important property of sensory networks forms in utero, while the development of associational networks is likely part of the rapid synaptogenesis and maturation of cortical activity patterns observed postnatally. Thus a close examination of activity in primary sensory co ...
... These data suggest that some important property of sensory networks forms in utero, while the development of associational networks is likely part of the rapid synaptogenesis and maturation of cortical activity patterns observed postnatally. Thus a close examination of activity in primary sensory co ...
Clinical neurochemistry
![](https://commons.wikimedia.org/wiki/Special:FilePath/Neuron_with_mHtt_inclusion.jpg?width=300)
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.