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A Confocal Laser Microscopic Study of Enkephalin
A Confocal Laser Microscopic Study of Enkephalin

In LHRH neurons
In LHRH neurons

... More recently, studies of GT-1 cells and LHRH neurons (from mouse olfactory placode) show that GABA actually stimulates LHRH release, as well as increasing intracellular Ca2+ oscillations and membrane ...
Ch. 2 - 서울대 Biointelligence lab
Ch. 2 - 서울대 Biointelligence lab

... ♦ Be synthesized by and localized within the presynaptic neuron, and stored in the presynaptic terminal. ♦ Be released by the presynaptic neuron when action potentials invade and depolarize the terminal. ♦ Contain receptors that are specific for the substance. ♦ When applied to the postsynaptic cell ...
Musings on the Wanderer: What`s New in Our Understanding of
Musings on the Wanderer: What`s New in Our Understanding of

... (46) examined the terminal fields formed by regenerating axons and endings. These investigators reported marked differences in the regenerative capacities of the afferent and efferent arms of the vagus under the same surgical and maintenance conditions. It was demonstrated that, in the rat, vagal af ...
Turtle Dorsal Cortex Pyramidal Neurons Comprise Two Distinct Cell
Turtle Dorsal Cortex Pyramidal Neurons Comprise Two Distinct Cell

... pyramidal neuron subtypes is partly motivated by the hypothesis that a subtype-specific division of labor could create a rich substrate for computation. On the other hand, the extreme integration of individual neurons into the collective cortical circuit promotes the hypothesis that cellular individ ...
Amyloid Precursor Protein in Cortical Neurons: Coexistence of Two
Amyloid Precursor Protein in Cortical Neurons: Coexistence of Two

... Cell surface biotinylation. Cells were washed three times in PBS pH 7.4 and incubated with sulfo-NHS-SS-biotin (Pierce Chemical) at 200 Ma/ml. 30 min at 4°C or 5 min at 37°C. These conditions were determined to give access to membrane constituents without altering the viability of the cells, as dete ...
Clonal analysis of the mushroom bodies
Clonal analysis of the mushroom bodies

... of neurons. Mapping this cellular organization is important in understanding the molecular basis of specific brain functions, such as learning and memory. A variety of techniques have been developed to resolve the neuronal networking at the single cell level. In particular, examining the entire morp ...
Diverse functions of perineuronal nets
Diverse functions of perineuronal nets

... These results indicate that tenascin-R is essential for ECM proteoglycans to form the lattice-like structure (Weber et al. 1999, Haunso et al. 2000). It appears that precise timing of the CS proteoglycans expression seems to be specific for both cortical areas and particular cortical layers. For exa ...
c-Jun Expression in Adult Rat Dorsal Root
c-Jun Expression in Adult Rat Dorsal Root

... prevented from contacting spinal cord tissue by a thin piece of durafilm (Cotman, Inc.). This paradigm insured that the cut DRG process could not contact any other tissue, so any cell body responses observed could be attributed to the central rhizotomy. In other animals, the same three lumbar dorsal ...
[Frontiers in Bioscience 8, s438-451, May 1, 2003] 438 AROUSAL
[Frontiers in Bioscience 8, s438-451, May 1, 2003] 438 AROUSAL

... fibers and thus have the capacity to receive input from those fibers and their multiple sources. From the medulla through the pons and into the midbrain, the reticular neurons acquire converging inputs from different sources including peripheral sensory systems relaying somatic or visceral sensory, ...
Dopamine is produced in the rat spinal cord and regulates
Dopamine is produced in the rat spinal cord and regulates

... neurons and the pontine micturition center. Here we show that DA is produced in the rat spinal cord and modulates the bladder reflex. We observed numerous tyrosine hydroxylase (TH)+ neurons in the autonomic nuclei and superficial dorsal horn in L6–S3 spinal segments. These neurons are dopamine-β-hydro ...
Functional characterization of the synaptic
Functional characterization of the synaptic

... Epilepsy is a neurodevelopmental disorder affecting almost 1 % of the population all over the world (Elger 2002; Fisher et al. 2005). Neurodevelopmental disorders comprise diseases that develop early in brain or as a consequence of head trauma, a tumor or an infection in the adult brain and span thr ...
Neurons, Brain Chemistry, and Neurotransmission
Neurons, Brain Chemistry, and Neurotransmission

... synaptic cleft. An average neuron forms approximately 1,000 synapses with other neurons. It has been estimated that there are more synapses in the human brain than there are stars in our galaxy. Furthermore, synaptic connections are not static. Neurons form new synapses or strengthen synaptic connec ...
- Hayden Lab
- Hayden Lab

... (r = 0.218, p = 0.006) (Figure 4B). We confirmed the significance of this correlation using a bootstrap correlation test (p = 0.0061; see Experimental Procedures). To match the criteria used above, these analyses do not include trials with safe options; however, if we repeat the analysis but include ...
Patterning and axon guidance of cranial motor neurons
Patterning and axon guidance of cranial motor neurons

... are involved in elaborating axon projections have also been characterized. However, many important questions remain. The unique features of the differentiation programmes of each of the cranial nerves are only partly characterized. In particular, we know little about how patterning genes dictate the ...
Gao JCN 2000 - Georgia State University
Gao JCN 2000 - Georgia State University

... cortex matured. However, this maturational pattern was interrupted by an unexpected surge in the proportion of GABA-ir neurons at postnatal day (P) 60. This occurred long after the cortical layers were in place, and near the close of the critical period for ocular dominance plasticity (Chapman et al ...
Surround suppression explained by long-range
Surround suppression explained by long-range

... excitatory activity14, 15 , while inhibitory activity becomes stronger and less selective15 . How does this reduction in response correlation come about, given the prevalence of strong spatial and temporal correlations present in natural visual scenes7, 8 , and given that neurons in a column share c ...
I Know What You Are Doing: A - Università degli Studi di Parma
I Know What You Are Doing: A - Università degli Studi di Parma

... observation of one action only, while the remainders responded to the observation of two actions. Neurons responding to grasping and holding and to grasping and manipulating typically started to discharge at the end of the hand transport phase, while grasping neurons started to discharge either at t ...
Neurons in Anterior Cingulate Cortex Multiplex
Neurons in Anterior Cingulate Cortex Multiplex

... cosine curve fit to the randomized points using the procedure described Duke University Medical Center, on a 3 T MR Imaging Instrument using above. (For neurons that were found to be bimodal by the fitting proce1 mm slices. We confirmed that electrodes were in ACC using stereotacdure, we generated r ...
Linking Neural Activity to Visual Perception: Separating Sensory and
Linking Neural Activity to Visual Perception: Separating Sensory and

... ‘fast’, ‘far’ or ‘near’, are some of the simplest features that we can assign to a visual stimulus and are some of the basic attributes that we can perceive. But the transition from neural activity to perception is not simple and remains largely unknown. This process is not intractable, however, and ...
Central mechanisms of osmosensation and systemic osmoregulation
Central mechanisms of osmosensation and systemic osmoregulation

... information into electrical signals that can persist even during prolonged perturbations50. Studies involving electro­physiological recording (FIG. 4c,d), functional imaging (FIG. 4a,b) or the expression of activity-dependent immediate-early genes such as Fos91 have shown that many subsets of neuron ...
Altered Patterns of Dynorphin lmmunoreactivity Suggest
Altered Patterns of Dynorphin lmmunoreactivity Suggest

... junction of CA3 and CA2 (arrow). No specific staining is evident in the granule cell (G) layer or supragranular region of the molecular (M) layer. Scale bar, 500 pm. B, Within the polymorph layer, reaction product is concentrated in clumps (arrowheads) of punctate structures near the proximal portio ...
Limitations of Neural Map Topography for Decoding Spatial
Limitations of Neural Map Topography for Decoding Spatial

... show in the developing zebrafish that topographic decoding performs very poorly compared with methods that do not rely on topography. This suggests that, although wiring topography could provide a starting point for decoding at a very early stage in development, it may be replaced by more accurate m ...
PDF+Links
PDF+Links

... area (morphometric parameter), as well as intensity of their staining (ROD — relative optical density, semiquantitative densitometric parameter developed by the software) was done at 400 ´ magnification. All consecutive sections of each series were analyzed. The neuronal counts were summarized using ...
Title - HAL
Title - HAL

... structures. In this perspective, we present a model derived from the experimental data one of the authors obtained in a detailed quantitative study of the main primate striatal and pallidal neurons (Yelnik et al.,1984; Yelnik et al.1991). The striatal cells were medium spiny neurons (MSNs), which re ...
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Multielectrode array

Multielectrode arrays (MEAs) or microelectrode arrays are devices that contain multiple plates or shanks through which neural signals are obtained or delivered, essentially serving as neural interfaces that connect neurons to electronic circuitry. There are two general classes of MEAs: implantable MEAs, used in vivo, and non-implantable MEAs, used in vitro.
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