Impact of left ventricular volume/mass ratio on diastolic function
... impact of aging on diastolic function, we first randomly sampled healthy controls out of this population (n ¼ 74, average age 41 + 15 years, range 18 – 76 years). This sample size yields a two-sided power (beta) of 80% to detect a correlation of 0.325 or greater at the alpha level of ,0.05. To asses ...
... impact of aging on diastolic function, we first randomly sampled healthy controls out of this population (n ¼ 74, average age 41 + 15 years, range 18 – 76 years). This sample size yields a two-sided power (beta) of 80% to detect a correlation of 0.325 or greater at the alpha level of ,0.05. To asses ...
as a PDF
... passing through the Purkinje fibres before dissipating into the myocardium. The endocardial electrical BO (as observed using noncontact mapping) is shown by the blue circle. (B) Pacing lead locations for the right atrial appendage (RAA-intrins), right ventricular septum (RVS), right ventricular apex ...
... passing through the Purkinje fibres before dissipating into the myocardium. The endocardial electrical BO (as observed using noncontact mapping) is shown by the blue circle. (B) Pacing lead locations for the right atrial appendage (RAA-intrins), right ventricular septum (RVS), right ventricular apex ...
Single-site ventricular and biventricular pacing
... passing through the Purkinje fibres before dissipating into the myocardium. The endocardial electrical BO (as observed using noncontact mapping) is shown by the blue circle. (B) Pacing lead locations for the right atrial appendage (RAA-intrins), right ventricular septum (RVS), right ventricular apex ...
... passing through the Purkinje fibres before dissipating into the myocardium. The endocardial electrical BO (as observed using noncontact mapping) is shown by the blue circle. (B) Pacing lead locations for the right atrial appendage (RAA-intrins), right ventricular septum (RVS), right ventricular apex ...
ASSOCIATE DIRECTOR SCIENTIFIC COORDINATION FDA NATIONAL TOXICOLOGY PROGRAM LIAISON
... of Torsade Proarrhythmia, under conditions of therapeutic use. Acrylamide and Glycidamide The presence of acrylamide in processed starchy foods first came to the attention of the FDA on April 24, 2002, when researchers at the Swedish National Food Administration and Stockholm University reported fin ...
... of Torsade Proarrhythmia, under conditions of therapeutic use. Acrylamide and Glycidamide The presence of acrylamide in processed starchy foods first came to the attention of the FDA on April 24, 2002, when researchers at the Swedish National Food Administration and Stockholm University reported fin ...
Circulation: Heart Failure Topic Review
... cardiomyopathy (PPCM) or joint occurrence of PPCM and idiopathic dilated cardiomyopathy (DCM) within families have been reported. The authors performed the first systematic study of the relation between PPCM and familial DCM. In a substantial number of DCM families (5/90), cases of PPCM were found, ...
... cardiomyopathy (PPCM) or joint occurrence of PPCM and idiopathic dilated cardiomyopathy (DCM) within families have been reported. The authors performed the first systematic study of the relation between PPCM and familial DCM. In a substantial number of DCM families (5/90), cases of PPCM were found, ...
Sudeen Cardiac Arrest Monograph
... system malfunctions, causing arrhythmias. The most common arrhythmia in cardiac arrest is ventricular fibrillation. Cardiac arrest may be reversed if CPR (cardiopulmonary resuscitation) is performed and a defibrillator is used to shock the heart and restore a normal heart rhythm within a few minutes ...
... system malfunctions, causing arrhythmias. The most common arrhythmia in cardiac arrest is ventricular fibrillation. Cardiac arrest may be reversed if CPR (cardiopulmonary resuscitation) is performed and a defibrillator is used to shock the heart and restore a normal heart rhythm within a few minutes ...
PDF
... plateau phase of the human action potential) separates the two.5,6 The mouse ventricular action potential lacks a clear plateau phase.4 Thus, repolarization starts when another part of the heart is not yet activated.2,7 Nevertheless, definitions of electrocardiographic deflections and intervals in t ...
... plateau phase of the human action potential) separates the two.5,6 The mouse ventricular action potential lacks a clear plateau phase.4 Thus, repolarization starts when another part of the heart is not yet activated.2,7 Nevertheless, definitions of electrocardiographic deflections and intervals in t ...
executive summary. - Heart Rhythm Society
... guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death— executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Com ...
... guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death— executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Com ...
Lifestyle management to prevent and treat atrial fibrillation
... impaired fasting glucose, and elevated triglycerides) was associated with an increased risk of AF. Importantly, the presence of each additional cardiovascular risk factor in a patient with metabolic syndrome further compounded their risk of developing AF [10]. Obesity is closely associated with OSA, ...
... impaired fasting glucose, and elevated triglycerides) was associated with an increased risk of AF. Importantly, the presence of each additional cardiovascular risk factor in a patient with metabolic syndrome further compounded their risk of developing AF [10]. Obesity is closely associated with OSA, ...
ACC/AHA/ESC 2006 Guidelines for Management
... guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death— executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Com ...
... guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death— executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Com ...
1443 Final Protocol - Medical Services Advisory Committee
... cryptogenous stroke and infarcts of unknown, uncertain, or undetermined cause. Embolic stroke of undetermined source (ESUS) is also a related term which describes a subset of CS. What is the underlying mechanism of cryptogenic stroke? Why the underlying mechanism of CS is not determined could be due ...
... cryptogenous stroke and infarcts of unknown, uncertain, or undetermined cause. Embolic stroke of undetermined source (ESUS) is also a related term which describes a subset of CS. What is the underlying mechanism of cryptogenic stroke? Why the underlying mechanism of CS is not determined could be due ...
Diagnostic Value of QRST Isointegral Maps in Detecting
... obvious underlying heart diseases (group RBBBN). The remaining 24 patients with RBBB (19 men, five women; mean age, 66.3 years) had the complication of an old myocardial infarction (group RBBBML). Of the 40 patients with LBBB, 22 (13 men, nine women; mean age 61.2 years) were without gross cardiovas ...
... obvious underlying heart diseases (group RBBBN). The remaining 24 patients with RBBB (19 men, five women; mean age, 66.3 years) had the complication of an old myocardial infarction (group RBBBML). Of the 40 patients with LBBB, 22 (13 men, nine women; mean age 61.2 years) were without gross cardiovas ...
Left Atrial Fibrosis
... patients per se. This includes increased atrial fibrosis seen in patients with advanced CHF,23 valvular heart disease,24,25 and ischemic heart disease.26 Increased atrial scar has also been seen in patients with lone AF,27 suggesting that even in those relatively healthy patients, there are fundamen ...
... patients per se. This includes increased atrial fibrosis seen in patients with advanced CHF,23 valvular heart disease,24,25 and ischemic heart disease.26 Increased atrial scar has also been seen in patients with lone AF,27 suggesting that even in those relatively healthy patients, there are fundamen ...
Disordered Myocardial Ca2+ Homeostasis Results
... involving increased spontaneous ectopic firing of atrial cells and impulse re-entry through the atrial tissue. Triggered activity as well as impairment of Ca2+ handling and cell-to-cell coupling that may lead to altered conduction properties and multiple re-entrant circuits are likely implicated in ...
... involving increased spontaneous ectopic firing of atrial cells and impulse re-entry through the atrial tissue. Triggered activity as well as impairment of Ca2+ handling and cell-to-cell coupling that may lead to altered conduction properties and multiple re-entrant circuits are likely implicated in ...
Left posterior hemiblock in acute myocardial infarction - Heart
... Fifteen cases of left posterior hemiblock associated with acute myocardial infarction were studied. In 5 cases the left posterior hemiblock was the only intraventricular conduction defect, while in the other rO cases it was associated with complete right bundle-branch block. Left posterior hemiblock ...
... Fifteen cases of left posterior hemiblock associated with acute myocardial infarction were studied. In 5 cases the left posterior hemiblock was the only intraventricular conduction defect, while in the other rO cases it was associated with complete right bundle-branch block. Left posterior hemiblock ...
Relations between heart failure, ejection fraction, arrhythmia
... committee classified the following occurrences based on standard prospective definitions developed in the Cardiac Arrhythmia Pilot Study (10) using all available historic and clinical evidence, with blinding to the specific therapy. Death~cardiac arrest. Death or cardiac arrest was defined as sponta ...
... committee classified the following occurrences based on standard prospective definitions developed in the Cardiac Arrhythmia Pilot Study (10) using all available historic and clinical evidence, with blinding to the specific therapy. Death~cardiac arrest. Death or cardiac arrest was defined as sponta ...
Is treating cardiac hypertrophy salutary or
... cardiac hypertrophy is essential hypertension in Western countries, virtually all forms of cardiac diseases, including valvular dysfunction, coronary artery disease, and arrhythmias, can stimulate development of cardiac hypertrophy. Hypertrophy also occurs in several systemic diseases, such as endoc ...
... cardiac hypertrophy is essential hypertension in Western countries, virtually all forms of cardiac diseases, including valvular dysfunction, coronary artery disease, and arrhythmias, can stimulate development of cardiac hypertrophy. Hypertrophy also occurs in several systemic diseases, such as endoc ...
Progressive Caloric Restriction Induces Dose
... (1, 10 –13). Using this method, Reingold et al. (14) documented that fasting for 48 h increases plasma FFA levels and myocardial TG content in healthy subjects, whereas myocardial TG content did not change after a single high fat meal. In another, cross-sectional study, Kankaanpää et al. (12) show ...
... (1, 10 –13). Using this method, Reingold et al. (14) documented that fasting for 48 h increases plasma FFA levels and myocardial TG content in healthy subjects, whereas myocardial TG content did not change after a single high fat meal. In another, cross-sectional study, Kankaanpää et al. (12) show ...
Automated Analysis of the 12-lead ECG in the Emergency
... from the JHH ECG MUSE database (GE Healthcare, Wauwatosa, WI) for subsequent analysis. All 12-lead ECGs used in the study were recorded using the GE-Marquette MAC 5000 ECG system (GE Medical Systems, Milwaukee, WI) at the JHH ED in the time period from January 16, 2012 to June 22, 2012. Each 12-lead ...
... from the JHH ECG MUSE database (GE Healthcare, Wauwatosa, WI) for subsequent analysis. All 12-lead ECGs used in the study were recorded using the GE-Marquette MAC 5000 ECG system (GE Medical Systems, Milwaukee, WI) at the JHH ED in the time period from January 16, 2012 to June 22, 2012. Each 12-lead ...
Chapter 28: Pacemakers and Implantable
... myocardium and serves as the ______________________ pole of the pacing circuit. 26. In a bipolar lead, the end of the lead is a metal tip that contacts myocardium and serves as the negative pole, and the _______________________ poles is an exposed metal ring located a few millimeters proximal to the ...
... myocardium and serves as the ______________________ pole of the pacing circuit. 26. In a bipolar lead, the end of the lead is a metal tip that contacts myocardium and serves as the negative pole, and the _______________________ poles is an exposed metal ring located a few millimeters proximal to the ...
The protective effects of a phosphodiesterase 5 inhibitor
... 30 minutes and 1, 2, 4 and 6 hours after ROSC. At the end of each time point, 4°C saline was injected into the right atrium through the Swan-Ganz catheter to determine CO by the transpulmonary thermodilution method as described previously [16]. MAP was determined by the electronic integration of th ...
... 30 minutes and 1, 2, 4 and 6 hours after ROSC. At the end of each time point, 4°C saline was injected into the right atrium through the Swan-Ganz catheter to determine CO by the transpulmonary thermodilution method as described previously [16]. MAP was determined by the electronic integration of th ...
Heart failure with preserved ejection fraction
... contractility are subtly but significantly depressed in HFpEF, compared with hypertensive and healthy controls.30 Importantly, the extent of myocardial contractile dysfunction in HFpEF was associated with increased mortality, suggesting that it may be a mediator or nominally a marker of more severe ...
... contractility are subtly but significantly depressed in HFpEF, compared with hypertensive and healthy controls.30 Importantly, the extent of myocardial contractile dysfunction in HFpEF was associated with increased mortality, suggesting that it may be a mediator or nominally a marker of more severe ...
Executive Summary - European Society of Cardiology
... Priori SG, Quinones MA, Roden DM, Silka MJ, Tracy C. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death—executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European ...
... Priori SG, Quinones MA, Roden DM, Silka MJ, Tracy C. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death—executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European ...
as PDF
... inward current to slowly depolarize the membrane during diastole, which is critical in initiating the pacemaker activity (Figure 1, upper panel). In the ventricular myocytes, due to the presence of a large IK1 and low expression If, there is no diastolic depolarization under physiological conditions ...
... inward current to slowly depolarize the membrane during diastole, which is critical in initiating the pacemaker activity (Figure 1, upper panel). In the ventricular myocytes, due to the presence of a large IK1 and low expression If, there is no diastolic depolarization under physiological conditions ...
Repaired tetralogy of Fallot: the roles of cardiovascular magnetic
... the short term, the impaired contractility may be reversible, and elimination of the volume load can result in recovery of pump function. 4) Irreversible myocardial injury associated with fibrosis and increased interstitial collagen [28]. Although valve replacement may still be tolerated and of clin ...
... the short term, the impaired contractility may be reversible, and elimination of the volume load can result in recovery of pump function. 4) Irreversible myocardial injury associated with fibrosis and increased interstitial collagen [28]. Although valve replacement may still be tolerated and of clin ...
Ventricular fibrillation
Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.