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Right ventricular failure in patients with the HeartMate
Right ventricular failure in patients with the HeartMate

... attractive therapeutic option for select patients, only 2000 heart transplantations are performed each year in the United States, largely as a result of donor shortages.2 This continued limitation underscores the need for alternative avenues of treatment for this patient cohort. Mechanical circulato ...
Linking left ventricular function and mural architecture: what does
Linking left ventricular function and mural architecture: what does

... mural thickness, the endocardial circumferential shortening strain, and the ratio of mural thickening. By replacing the endocardial diameter with the value for any particular depth within the wall, the same sequence generated an array of circumferential strains. We show such an analysis in figure 2, ...
ACC/AHA Guidelines for Ambulatory - Doctors
ACC/AHA Guidelines for Ambulatory - Doctors

... that time frame. Intermittent recorders may be used for long periods of time (weeks to months) to provide briefer, intermittent recordings to investigate events that occur infrequently. Two basic types of intermittent recorders have slightly different utility. A loop recorder, which is worn continuo ...
Correlation between P Wave Dispersion, QRS Duration and QT
Correlation between P Wave Dispersion, QRS Duration and QT

... admission and continuing until the peak is reached or until 3 sets of results are negative. Biochemical biomarkers are useful for diagnosis and prognostication. Of note, cardiac-specific troponins are not detectable in the blood of healthy individuals; therefore, they provide high specificity for de ...
What Do We Know About the “Malignant€Form”€of Early
What Do We Know About the “Malignant€Form”€of Early

... (6). Only the horizontal form (B) was associated with increased arrhythmic mortality during long-term follow-up. (Middle panel) The 2 electrocardiograms (ECGs) presented in the study by Cappato et al. (18) associating early repolarization with unexplained arrhythmic death in athletes: the ECG on the ...
of End-Diastolic Volume
of End-Diastolic Volume

... a proximal aortic flow probe, central aortic and ventricular micromanometers, and a conductance catheter for ventricular chamber volume. Preload was transiently reduced by left atrial hemorrhage, and afterload was increased by intraortic balloon inflation. Inotropic state was pharmacologically alter ...
the Frank-Starling Mechanism
the Frank-Starling Mechanism

... T o improve myocardial contractility, several compensatory mechanisms can be activated; one of these is the Frank-Starling mechanism, in which an increased preload enhances contractile force. In the nonfailing heart, an increase of the diastolic volume of the heart is associated with an improvement ...
Print this article - Bangladesh Journals Online
Print this article - Bangladesh Journals Online

... had Echo-LVH. This finding is very much consistent with the Copenhagen City Heart Study.12 Sensitivity of ECG in comparison to Echocardiography was calculated to be 87.50% which is consistent with various other studies.9 ...
Spatial gradients in action potential duration created by regional
Spatial gradients in action potential duration created by regional

... Clinical and experimental evidence supports the hypothesis that fibrillation results from the activity of a small number of high-frequency re-entrant sources (rotors) localized in one cardiac chamber (atrium or ventricle), with fibrillatory conduction to the contralateral chamber (Samie et al. 2001; ...
Name of presentation
Name of presentation

... – Unlike RBBB, not usually benign ...
Heart Online First, published on December 30, 2005 as 10.1136/hrt.2005.077164
Heart Online First, published on December 30, 2005 as 10.1136/hrt.2005.077164

... dysfunction plays an important role in reperfusion injury. It is unknown whether this beneficial effect of tirofiban is also partly due to endothelial protection. Methods Area of no-reflow was determined with both myocardial contrast echocardiography and pathological means in forty mini-swines rando ...
Isovolumetric Relaxation?
Isovolumetric Relaxation?

... Inferior vena cava occlusion with simultaneous hemodynamic monitoring was performed at the time of cardiac catheterization in eight patients. One patient developed transient atrial fibrillation, and a second had simultaneous falls in preload and afterload. These two patients were excluded from data ...
Myocardial Infarction Analysis Based on ST
Myocardial Infarction Analysis Based on ST

... tumor compressing the right ventricle outflow, dysplasia or arrhythmogenic right ventricle cardiomyopathy, long QT syndrome, early repolarization syndrome, Brugada syndrome27, arterial pressure reduction and pericarditis15. Nevertheless, ST-segment elevation is an important tool for diagnosing and f ...
Charles Hoopes, MD - American Heart Association
Charles Hoopes, MD - American Heart Association

... shock provides little or no additional benefit and in the short term may be detrimental by delaying definitive support ECLS is an effective method of early resuscitation of the moribund patients in shock … its effectiveness depends on end organ ischemic time, early ventricular recovery, or use of mo ...
Full Text - Cresco | Online Publication Company
Full Text - Cresco | Online Publication Company

... were located in the central part in bands, which did not contain muscle fibres. Conductive tissue in these moderator bands was represented by clumps of Purkinje cells, surrounded by myocardial fibres. The proportion of conductive cells and muscle fibres was approximately the same. Slight vascularizatio ...
Circulation Research SEPTEMBER
Circulation Research SEPTEMBER

... after electrical pacing of the right ventricle. Left ventricular pressure response to aortic constriction was measured during each of the periods, before isoproterenol and at the peak isoproterenol effect. Electrical pacing of the heart at 430 beats/min in another group of normal animals did not alt ...
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function

... present in virtually all patients with heart failure1– 4 as well as in less severe conditions.5–7 From a mechanistic point of view, it can be traced to abnormalities of left ventricular (LV) distensibility, filling, or relaxation.8 These alterations may coexist and act in synergy to influence LV dia ...
PowerPoint - Electrocardiography
PowerPoint - Electrocardiography

... when a wavefront spreads toward an electrode, the largest possible deflection will occur When a wavefront spreads perpendicular to a lead, the smallest or no deflection occurs ECG shows the sum of all wavefronts relative to the lead being used to measure (MEA) ...
Increased Phosphorylation of Ca2+ Handling Proteins as a - J
Increased Phosphorylation of Ca2+ Handling Proteins as a - J

... yocarditis, and subsequent dilated cardiomyopathy (DCM), is a major cause of heart failure and arrhythmia in young patients.1,2 This condition is characterized by infiltration of inflammatory cells into the myocardium with cellular injury, consequent loss of myocytes and development of fibrosis and ...
Interpreting AV (Heart) Blocks: Breaking Down the Mystery
Interpreting AV (Heart) Blocks: Breaking Down the Mystery

... When the impulse leaves the atria and travels to the AV node it encounters a slight delay. The tissues of the node do not conduct impulses as fast as the other cardiac electrical tissues. This means that the wave of depolarization will take a longer time to get through the AV node. On the ECG this i ...
Cardiac repolarization analysis using the surface - DIEC
Cardiac repolarization analysis using the surface - DIEC

... heart, gives the AP its spike-and-dome morphology. In phase 2, the influx of calcium through the L-type calcium channel (ICaL) compensates the repolarizing currents, delaying repolarization and creating a slow-decaying plateau. During phase 3, potassium currents, mainly the delayed rectifier currents, ...
Calibrated integrated backscatter and
Calibrated integrated backscatter and

... between cIB and fibrosis in patients with less extensive fibrosis. We have shown that left ventricular functional abnormalities of the metabolic syndrome and type 2 diabetes are not associated with increased myocardial fibrosis.8 In addition, factors other than fibrosis may influence cIB.9–16 cIB increas ...
Mortality Study of the Significance of Extrasystoles in an
Mortality Study of the Significance of Extrasystoles in an

... the expected number of deaths. They consist of: (a) persons who had been insured at standard rates for not more than 15 years and whose mortality was observed between 1955 and 1960 for each age and duration of exposure (the Male Intercompany 1955-1960 Basic Select Tables); and (b) persons who had be ...
New Insights into Mechanisms of Atrial Fibrillation
New Insights into Mechanisms of Atrial Fibrillation

... support in the experimental work of Allessie et al. (1985). It appears that all three concepts are non-exclusive and each may be applicable to certain subgroups of AF patients, or that they may even coexist in the same subject during different stages of AF development. The probability of development ...
Molecular and Cellular Basis for Diastolic Dysfunction
Molecular and Cellular Basis for Diastolic Dysfunction

... sarcomere length (SL) range of 1.8–2.2 μm, titin was identified as the dominant determinant of LV passive pressure, contributing approximately 80 % to LV passive stiffness, while the contribution of the ECM appeared more important at an SL higher than 2.2 μm [34]. Cardiomyocyte titin-based elasticit ...
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Ventricular fibrillation



Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.
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